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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article"><?properties manuscript?><front><journal-meta><journal-id journal-id-type="nlm-journal-id">8802265</journal-id><journal-id journal-id-type="pubmed-jr-id">21671</journal-id><journal-id journal-id-type="nlm-ta">J Fam Psychol</journal-id><journal-id journal-id-type="iso-abbrev">J Fam Psychol</journal-id><journal-title-group><journal-title>Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)</journal-title></journal-title-group><issn pub-type="ppub">0893-3200</issn><issn pub-type="epub">1939-1293</issn></journal-meta><article-meta><article-id pub-id-type="pmid">26751757</article-id><article-id pub-id-type="pmc">4767617</article-id><article-id pub-id-type="doi">10.1037/fam0000167</article-id><article-id pub-id-type="manuscript">NIHMS742106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Daily Parental Knowledge of Youth Activities Is Linked to Youth Physical Symptoms and HPA functioning</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Lippold</surname><given-names>Melissa A.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Davis</surname><given-names>Kelly D.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>McHale</surname><given-names>Susan M.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">c</xref></contrib><contrib contrib-type="author"><name><surname>Almeida</surname><given-names>David M.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">c</xref></contrib></contrib-group><aff id="A1"><label>a</label>The University of North Carolina at Chapel Hill</aff><aff id="A2"><label>b</label>Oregon State University</aff><aff id="A3"><label>c</label>The Pennsylvania State University</aff><author-notes><corresp id="CR1"><bold>Please direct correspondence to:</bold> Melissa Lippold, Ph.D., The University of North Carolina at Chapel Hill, School of Social Work, Tate-Turner Kurlat Bldg, 325 Pittsboro St. CB #3550, Chapel Hill, NC 27599-3550, Phone: 814-933-8454; Fax: 919-843-8715; <email>mlippold@unc.edu</email></corresp><corresp id="CR2"><bold>Other author contact information:</bold> Susan M. McHale, Ph.D., 114 Henderson (North), The Pennsylvania State University, University Park PA 16802, 814-865-2663, <email>x2u@psu.edu</email>, Kelly D. Davis, Ph.D., College of Public Health and Human Sciences, 418 Waldo Hall, Corvallis, OR 97331, 541-737-7243, <email>Kelly.Davis@oregonstate.edu</email>, David Almeida, Ph.D., 403 BBH Building, The Pennsylvania State University, University Park PA 16802, 814-865-2656, <email>dalmeida@psu.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>14</day><month>12</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>11</day><month>1</month><year>2016</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2016</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>3</month><year>2017</year></pub-date><volume>30</volume><issue>2</issue><fpage>245</fpage><lpage>253</lpage><!--elocation-id from pubmed: 10.1037/fam0000167--><abstract><p id="P1">Considerable evidence documents linkages between parental knowledge of youth activities and youth risky behavior. We extended this research to determine whether parental knowledge was associated with youth physical health, including reports of physical symptoms (e.g., headaches, stomachaches) and a biomarker of hypothalamic pituitary adrenocortical (HPA) axis functioning (i.e., salivary cortisol levels). Participants were children of employees in the Information Technology division of a Fortune 500 company (<italic>N</italic> = 132, Mean Age Youth = 13.39 years, 55% female) who participated in a daily diary study. Data were collected via telephone calls on eight consecutive evenings. On four study days, cortisol samples were collected at 4 time points (waking, 30 min after waking, before dinner, bedtime). Multi-level models revealed that, at the between-person level, youth whose parents had higher average knowledge about their activities, exhibited lower bedtime cortisol levels. Furthermore, at the within-person level, on days when parents displayed more knowledge than usual (relative to their own eight-day average), youth had lower before-dinner cortisol than usual. Linkages between average parental knowledge and physical health symptoms were moderated by youth age: Younger but not older adolescents whose parents were more knowledgeable had fewer physical health symptoms, on average. A next step is to identify the processes that underlie these associations.</p></abstract><kwd-group><kwd>parental knowledge</kwd><kwd>daily diary</kwd><kwd>physical health</kwd><kwd>HPA system</kwd><kwd>cortisol</kwd></kwd-group></article-meta></front><body><p id="P2">Parental knowledge about youth experiences, activities, whereabouts, and companions, has been linked to lower levels of youth risky behaviors (<xref rid="R11" ref-type="bibr">Crouter &#x00026; Head, 2002</xref>; <xref rid="R27" ref-type="bibr">Lippold, Coffman &#x00026; Greenberg, 2014</xref>; <xref rid="R27" ref-type="bibr">Lippold, Greenberg, Graham, &#x00026; Feinberg, 2014</xref>; <xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>). Parents&#x02019; knowledge emerges from youth's self-disclosures to them as well as through parents&#x02019; own efforts to solicit information or exert behavioral control (<xref rid="R20" ref-type="bibr">Kerr, Stattin, &#x00026; Burk, 2010</xref>; <xref rid="R29" ref-type="bibr">Lippold, Greenberg, &#x00026; Collins, 2013</xref>), with a recent study showing that knowledge was associated with positive youth outcomes regardless of how parents obtained their knowledge (<xref rid="R27" ref-type="bibr">Lippold et al., 2014</xref>). Importantly, the larger literature on parental knowledge documents that it is one important means through which parents influence their children's well-being: Knowledge serves as a mediator that links both parental solicitation and child disclosure to youth outcomes (<xref rid="R29" ref-type="bibr">Lippold et al., 2013</xref>; <xref rid="R49" ref-type="bibr">Vieno, Nation, Pastore, &#x00026; Santaniello, 2009</xref>). In the face of its significance as a dimension of parenting, however, research on parental knowledge has focused on youth risky behavior outcomes, and we know little about whether parental knowledge has implications for other domains of youth well-being. Accordingly, this study built on prior research to test the relations between parental knowledge and youth's physical health outcomes, including youth's health symptoms and stress-related physiology. The latter was assessed by a biomarker of hypothalamic pituitary adrenocortical (HPA) axis functioning -- salivary cortisol levels. Our second goal was to test whether the links between knowledge and youth health were moderated by youth age and/or gender. These findings may illuminate possible intervention targets, such as strategies that may increase parent-child communication and knowledge, for family-based interventions aimed to promote physical health during adolescence.</p><sec id="S1"><title>A Daily Diary Approach</title><p id="P3">We used a daily diary approach to test the linkages between knowledge and youth physical symptoms and HPA functioning. Most studies of parental knowledge rely on global reports, whereby parents and/or youth rate parents&#x02019; average level of knowledge, usually over the past month (<xref rid="R27" ref-type="bibr">Lippold et al., 2014</xref>; <xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>). Although such global reports have been linked to youth outcomes, they can be limited by response biases and memory demands. Further, both knowledge and youth health may fluctuate on a day-to-day basis (<xref rid="R4" ref-type="bibr">Almeida, 2005</xref>). That is, parents may be more knowledgeable and youth may experience more health symptoms on some days than on others. Diary data can be used to investigate two types of associations. Between-person associations test whether or not average levels of knowledge are linked to better youth health outcomes. Within-person associations test whether, on days parents are more knowledgeable than usual (i.e., relative to their own cross-day average), youth have more positive health outcomes than usual that same day. Such within-person analyses control for stable between-person differences, or selection effects, and thereby allow for stronger inferences about the links between knowledge and health. Thus, in this study we used multi-level modeling (MLM) to analyze links between average levels of parental knowledge (between-person associations) and youth health, as well as to assess whether day-to-day variations in parents&#x02019; knowledge were linked to same day variations in youth health (within-person associations).</p><p id="P4">As noted, we assessed youth's physical health in terms of both health symptoms and HPA functioning. We used salivary cortisol as a biomarker of youth's stress-related physiology. Healthful patterns of cortisol&#x02014;the hormonal byproduct of the HPA system&#x02014;are marked by a diurnal rhythm wherein cortisol levels peak shortly after waking and then decline over the course of the day (<xref rid="R33" ref-type="bibr">McEwen, 1998</xref>). To the extent that parental knowledge is linked to better HPA functioning, the cortisol levels of youth with more knowledgeable parents should exhibit a healthful pattern of rising sharply in the morning, and then declining across the course of the day, resulting in low levels of cortisol before dinner and at bedtime. Dysregulated HPA functioning has been linked to disrupted immune processes and an increased risk of disease (<xref rid="R35" ref-type="bibr">Miller, Chen, &#x00026; Parker, 2011</xref>; <xref rid="R36" ref-type="bibr">Neeck, Federlin, Graef., Rusch Schmidt, 1990</xref>; <xref rid="R41" ref-type="bibr">Repetti, Robles, &#x00026; Reynolds, 2011</xref>). However, the causal process that may link HPA functioning and illness and disease are not yet clear (<xref rid="R35" ref-type="bibr">Miller et al., 2011</xref>). Thus, we assessed both physical health symptoms and salivary cortisol in this study.</p></sec><sec id="S2"><title>Parental Knowledge and Youth Physical Health and HPA Functioning</title><p id="P5">Our study is grounded in prior research and theory suggesting that parental knowledge may have important linkages to health behaviors and youth stress, with positive implications for their HPA functioning and fewer physical health symptoms. In this study, we assessed the direct associations between parental knowledge and indices of HPA functioning and youth physical health.</p><p id="P6">Parental knowledge may be linked to youth stress-related physiology and physical health symptoms and at both daily and average levels. If parents are knowledgeable about their youth experiences on a particular day, they may be more likely to be aware of and promote behaviors and routines that improve physical health and reduce youth stress-- such as exercising, sleeping, and eating well (<xref rid="R8" ref-type="bibr">Buckley &#x00026; Schatzberg, 2005</xref>; <xref rid="R9" ref-type="bibr">Cohen, 2004</xref>; <xref rid="R34" ref-type="bibr">Meerlo, Koehl, van der Borght, &#x00026; Turek, 2002</xref>; <xref rid="R37" ref-type="bibr">Pedersen &#x00026; Hoffman-Goetz, 2000</xref>; <xref rid="R45" ref-type="bibr">Traustad&#x000f3;ttir, Bosch, &#x00026; Matt, 2005</xref>). In addition, knowledgeable parents may be more aware of their children's physical well-being and thus more likely to intervene in ways that prevent illness and promote more rapid recovery when their children do become ill. For example, parents may limit their children's exposure to friends who are ill or provide medication and arrange doctors&#x02019; visits. Some of the linkages between knowledge and youth health may occur on the same day: For example, parents who know that a child is not feeling well may encourage more restful activities, resulting in fewer physical symptoms and healthier HPA functioning on that same day. Yet, some of the associations between parental knowledge and youth health may be cumulative, and it may be that average parental knowledge, rather than knowledge on particular day, is most closely linked to physical health and HPA functioning. For example, the effects of parenting practices such as enforcing curfews and bedtimes, encouraging a balanced diet, and promoting physical activity may not be immediate, but build up over time (<xref rid="R9" ref-type="bibr">Cohen, 2004</xref>; <xref rid="R48" ref-type="bibr">Umberson, Crosnoe, &#x00026; Reczek, 2010</xref>; <xref rid="R22" ref-type="bibr">Kitzman-Ulrich et al., 2010</xref>). Therefore, average levels of knowledge may also be important for promoting healthy HPA functioning and physical health.</p><p id="P7">Furthermore, when their parents are more knowledgeable about their activities, whereabouts and companions, youth may develop a sense of safety and security, which in turn, buffers youth against the effects of stressors (<xref rid="R12" ref-type="bibr">Cummings &#x00026; Davies, 1996</xref>). Youth with knowledgeable parents may feel more comfortable communicating with their parents and therefore may experience greater parental support and advice. Social support has been linked to improved physical health and HPA functioning among adults (<xref rid="R31" ref-type="bibr">Lutgendorf et al., 2005</xref>; <xref rid="R46" ref-type="bibr">Turner-Cobb, Sephton, Koopman, Blake-Mortimer, &#x00026; Spiegel, 2000</xref>), as well as fewer physiological responses when faced with a stressor (<xref rid="R47" ref-type="bibr">Uchino, 2006</xref>). Similarly, because of improved communication and problem solving support, youth with knowledgeable parents may experience fewer stressors and may appraise stressors are less threatening with weaker physiological responses to those stressors (<xref rid="R6" ref-type="bibr">Bai &#x00026; Repetti, 2015</xref>; <xref rid="R39" ref-type="bibr">Power, 2004</xref>). Therefore, on a particular day, youth with parents who are knowledgeable may experience fewer physical symptoms and healthier cortisol patterns that same day. However, the effects of parental knowledge on youth health may also be cumulative. It may be that only when parents have high knowledge across many days that youth may develop a strong sense of safety and support. Thus, average levels of knowledge may also have associations with youth physical symptoms and HPA functioning.</p><p id="P8">The linkages between parental knowledge and health may also be due to child effects: Children's health may influence the level of knowledge that their parents obtain. Parental knowledge is a transactional process, with parents providing support and seeking information and youth making decisions about what information to share with parents (<xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>). Thus, youth with better health and HPA functioning may be more likely to share information with their parents, resulting in more knowledge (<xref rid="R44" ref-type="bibr">Stattin &#x00026; Kerr, 2000</xref>). In contrast, those who experience stressors and physical symptoms may withdraw and fail to disclose information to their parents. Parents may also track the activities of their children who are ill more than children who are healthy. Perceptions also may matter: Youth with better health may perceive their parents as more engaged and helpful, leading to greater disclosure.</p><p id="P9">For these and other reasons, higher levels of both daily and average parental knowledge may be linked to fewer youth physical health symptoms such as headaches and stomachaches as well as more healthful HPA functioning. As such, an important step is to examine the links between parental knowledge and indices of youth's physical health. Establishing linkages between knowledge and youth health is an important first step that may lay the groundwork for future studies that unpack the mechanisms through which knowledge exerts its effects on youth health.</p></sec><sec id="S3"><title>Variations in Knowledge-Health Linkages by Youth Gender and Age</title><p id="P10">The associations between parental knowledge and youth health may vary as a function of youth characteristics, in particular, gender and age. Moderation analysis may shed light on subgroups to target in family-based interventions aimed to improve child health. First, theory and research suggest that parents monitor girls more than boys and that girls disclose more information to their parents (<xref rid="R50" ref-type="bibr">Waizenhofer, Buchanan, &#x00026; Jackson-Newsom, 2004</xref>). Further, girls tend to be more relationship-oriented than boys (<xref rid="R26" ref-type="bibr">Leaper, 2002</xref>), with the result that they may be more strongly affected by parental knowledge, and knowledge may be more predictive of health for girls than boys.</p><p id="P11">Parental knowledge may also have a stronger impact on the health of younger as compared to older adolescents. With age, youth spend less time with their parents and more unsupervised time with their peers, making it more difficult for parents to obtain knowledge about their activities (<xref rid="R25" ref-type="bibr">Larson, Richards, Moneta, Holmbeck, &#x00026; Duckett, 1996</xref>), and several studies documented declines in parental knowledge across adolescence (<xref rid="R23" ref-type="bibr">Laird, Pettit, Bates, &#x00026; Dodge, 2003</xref>; <xref rid="R32" ref-type="bibr">Masche, 2010</xref>). Further, youth become more self-directed around health behaviors with age. Food choices, decisions to engage in physical activities and bedtimes are increasingly viewed by adolescents as their own, rather than their parents&#x02019;, jurisdiction (<xref rid="R43" ref-type="bibr">Smetana, 2011</xref>). Thus, as children become older, knowledgeable parents may be less likely to promote specific health behaviors due to youth's increasing autonomy (<xref rid="R51" ref-type="bibr">Wray-Lake, Crouter, &#x00026; McHale, 2010</xref>). Further, as youth become older, they may share less information with their parents (<xref rid="R19" ref-type="bibr">Keijsers &#x00026; Poulin, 2013</xref>). Parents may be less aware of stressors that youth experience and therefore have fewer opportunities to provide support and guidance. Further, older adolescents may be more likely to spend time with and seek support from peers rather than parents in dealing with stressors (<xref rid="R25" ref-type="bibr">Larson et al., 1996</xref>). As such, the relation between parental knowledge and health may be stronger for younger than older adolescents.</p></sec><sec id="S4"><title>Current Study</title><p id="P12">In sum, we addressed two goals. First, we assessed the links between youth reports of parental knowledge and HPA functioning and physical health symptoms, testing two kinds of hypotheses: (a) At the between-person level, youth who reported lower levels of parental knowledge, on average, will also report more physical health symptoms and exhibit less healthful levels of cortisol (e.g., high levels of cortisol before dinner and at bedtime, flatter evening slopes, and blunter next-day morning rise); and (b) at the within-person level, controlling for average knowledge, on days when youth reported lower parental knowledge than usual, they also will report more physical health symptoms and exhibit less healthful cortisol patterns. Our second goal was to test whether the associations between parental knowledge and youth health were moderated by youth gender or age. We expected to find stronger associations between knowledge and youth health outcomes in girls and younger adolescents.</p></sec><sec sec-type="methods" id="S5"><title>Method</title><sec id="S6"><title>Participants and Procedure</title><p id="P13">We used data from families who participated in the daily diary component of the Work, Family Health Network Study (WFHS) conducted in a U.S. Fortune 500 company (<xref rid="R7" ref-type="bibr">Bray et al., 2013</xref>; <xref rid="R21" ref-type="bibr">King et al., 2012</xref>). Employees from the information technology (IT) division were recruited to participate in a workplace interview. Of the 823 employees who completed a workplace interview, 222 (26.7%), were eligible for home interviews because they were a parent of a child aged 9-17 who lived at home for at least four days a week. Families in which both employee and child completed the home interview (<italic>n</italic> = 147) were eligible to participate in a daily diary study involving telephone calls and saliva collection. Recruitment for the daily diary occurred after the workplace interview. One hundred thirty-two families (89.8% of those eligible) participated in the daily diary study. The employee-parent signed separate consent forms for his/her own and child's participation, and youth assent for the diary was obtained during the home interview. Parents and their children provided information on their daily activities, emotions, and experiences via telephone calls on eight consecutive evenings (<italic>Median</italic> child interview start time = 8:01 PM, <italic>SD</italic> = 1.62 hrs). Of those who agreed to participate, 84% of parents and 88% of youth completed all eight days of interviews.</p><p id="P14">The current analyses included 132 youth (55% female; mean age = 13.39, <italic>SD</italic> = 2.40). The majority of youth were White (59%); 3% were African American, 15% were Hispanic, 11% were Indian Asian, 7% were other Asian, less than 1% were American Indian/Alaska Native or Pacific Islander; 3% chose more than one race. Most parents graduated from college (78%), were married or cohabitating with a partner (87%), and annual income averaged between $110,000 and $119,999.</p><p id="P15">On four diary study days (days 2, 3, 4, and 5), saliva samples were collected from youth at four time points: upon awakening, 30 minutes after waking, before dinner, and before going to bed. During the home interviews, saliva collection kits with instructions were distributed. Each kit contained 16 salivettes for collecting youth cortisol (4 salivettes/day X 4 days) along with a DVD that demonstrated saliva collection procedures. Youth were instructed to roll a cotton swab across their tongue for two minutes and then return the swab to the tube without touching it and were told not to eat, drink, or brush their teeth within 30 minutes pre-collection. Instructions for saliva collection and data collection sheet completion were reviewed with parents and youth during the first phone interview, and youth were reminded about the saliva collection on the evenings prior to scheduled collections. Youth recorded the time of each saliva sample and any medications they were taking on a separate data collection sheet. Participants refrigerated saliva samples after collection and, at the end of the saliva collection period, mailed the samples to the laboratory using prepaid overnight delivery. Upon receipt at the laboratory, saliva samples were weighed and frozen at &#x02212;80 &#x000b0;C until later assay of cortisol in the Biomarker Core Laboratory at The Pennsylvania State University lab using commercially available EIA kits (Salimetrics, LLC, State College, PA). Assays were run on a rolling basis throughout the entire study period. The assay had a lower limit of sensitivity of 0.003 ug/dL, with average inter- and intra-assay covariances of less than 7% and 4%, respectively. Cortisol values below 0.003 ug/dL were designated as off-the-curve low and were set to the lowest level of sensitivity to the assay. Of the youth who participated in the diary calls, 96% (<italic>N</italic> = 126) also provided saliva samples.</p></sec><sec id="S7"><title>Measures</title><p id="P16"><italic>Parental knowledge</italic> was assessed in the youth phone interviews using a four-item, 4-point (1 = <italic>almost nothing,</italic> 4 = <italic>a lot</italic>) scale (<xref rid="R44" ref-type="bibr">Stattin &#x00026; Kerr, 2000</xref>). Youth were asked, &#x0201c;Since this time yesterday, how much did your parent really know about: &#x0201c;how you spent your free time?&#x0201d; &#x0201c;which friends you hung out with?&#x0201d; &#x0201c;where you went?&#x0201d; and &#x0201c;how well you behaved?&#x0201d; The average alpha across days was .86</p><p id="P17">Youth reported on their <italic>daily physical health symptoms</italic> during the telephone interviews using a five-item measure adapted from <xref rid="R24" ref-type="bibr">Larsen and Kasimatis (1991)</xref> which has been used across a variety of studies (<xref rid="R5" ref-type="bibr">Almeida &#x00026; Davis, 2011</xref>; <xref rid="R10" ref-type="bibr">Charles &#x00026; Almeida, 2006</xref>; <xref rid="R18" ref-type="bibr">Horn-Mallers, Almeida, &#x00026; Neupert, 2005</xref>; <xref rid="R42" ref-type="bibr">Seltzer et al., 2009</xref>). For each item (e.g., headache, very tired, allergies, stomachache, other physical problems or discomforts [not diseases]) youth reported whether they had or had not experienced the symptom that day (0 = <italic>no</italic>; 1 = <italic>yes</italic>). Responses were summed.</p><p id="P18"><italic>HPA functioning</italic> was assessed using four indicators of youth salivary cortisol: level of cortisol before dinner and at bedtime, dinner to bedtime slope, and the Cortisol Awakening Response (CAR). We focused on these end-of-day measures, reasoning that they would best reflect the effects of parental knowledge obtained during that day. Because the effects of knowledge may spill over to the next day (<xref rid="R13" ref-type="bibr">Flook, 2011</xref>), we also assessed the Cortisol Awakening Response on the following day. The Cortisol Awakening Response (CAR) was calculated as the difference between level of cortisol at wake and 30 minutes post-waking. Cortisol values expressed in nmol/l (ug/dL X 27.59) and were log transformed before analyses to adjust for skewness (<xref rid="R1" ref-type="bibr">Adam &#x00026; Kumari, 2009</xref>).</p><p id="P19"><italic>Moderators</italic> were youth gender (0 = <italic>male,</italic> 1 = <italic>female</italic>) and youth age centered at the grand mean. Given their links with parental knowledge and/or youth health in prior research (<xref rid="R1" ref-type="bibr">Adam &#x00026; Kumari, 2009</xref>; <xref rid="R11" ref-type="bibr">Crouter &#x00026; Head, 2002</xref>), we also included additional controls for race/ethnicity (0 = <italic>White;</italic> 1= <italic>Non-white</italic>), parent education (0 = <italic>Not a college graduate,</italic> 1= <italic>College graduate</italic>) and daily stressors (measured by the Daily Inventory of Stressful Events which summed 5 items that asked if youth had experienced a particular stressor in a given day (0 = <italic>no</italic>; 1 = <italic>yes</italic>). Consistent with prior research, cortisol models included time of cortisol sample collection and whether or not the child was taking medications that might impact cortisol levels (0 = <italic>no medication</italic>, 1= <italic>1 or more medications</italic>) as covariates (<xref rid="R1" ref-type="bibr">Adam &#x00026; Kumari, 2009</xref>).</p></sec><sec id="S8"><title>Plan of Analysis</title><p id="P20">We used multi-level models to account for the non-independence of the data (i.e., days clustered within individuals; <xref rid="R40" ref-type="bibr">Raudenbush &#x00026; Bryk, 2002</xref>). Two level models were estimated in SAS 9.3 using Proc Mixed, with days (level 1, within-person) clustered within individuals (level 2, between-person). At level 1, we included person-centered measures of the time varying knowledge measures. At level 2, we entered the between-person variables, which were grand mean centered, including the across time averages of daily stressors (person-mean). Models also controlled for parent education, youth age, and gender. Cortisol models also included time of sample collection, race-ethnicity, and medication use as control variables. <disp-formula id="FD1"><label>(1a)</label><mml:math display="block" id="M1" overflow="scroll"><mml:mrow><mml:mi>L</mml:mi><mml:mi>e</mml:mi><mml:mi>v</mml:mi><mml:mi>e</mml:mi><mml:mi>l</mml:mi><mml:mspace width="thickmathspace"/><mml:mn>1</mml:mn><mml:mo>:</mml:mo><mml:mi>Y</mml:mi><mml:mi>o</mml:mi><mml:mi>u</mml:mi><mml:mi>t</mml:mi><mml:mi>h</mml:mi><mml:mi>O</mml:mi><mml:mi>u</mml:mi><mml:mi>t</mml:mi><mml:mi>c</mml:mi><mml:mi>o</mml:mi><mml:mi>m</mml:mi><mml:mi>e</mml:mi><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>t</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mn>0</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>+</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mn>1</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mrow><mml:mo>(</mml:mo><mml:mi>P</mml:mi><mml:mi>a</mml:mi><mml:mi>r</mml:mi><mml:mi>e</mml:mi><mml:mi>n</mml:mi><mml:mi>t</mml:mi><mml:mi>a</mml:mi><mml:mi>l</mml:mi><mml:mspace width="thickmathspace"/><mml:mi>K</mml:mi><mml:mi>n</mml:mi><mml:mi>o</mml:mi><mml:mi>w</mml:mi><mml:mi>l</mml:mi><mml:mi>e</mml:mi><mml:mi>d</mml:mi><mml:mi>g</mml:mi><mml:msub><mml:mi>e</mml:mi><mml:mrow><mml:mi>t</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>)</mml:mo></mml:mrow><mml:mo>]</mml:mo></mml:mrow><mml:mo>+</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:msub><mml:mi>e</mml:mi><mml:mrow><mml:mi>t</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>]</mml:mo></mml:mrow></mml:mrow></mml:math></disp-formula><disp-formula id="FD2"><label>(1b)</label><mml:math display="block" id="M2" overflow="scroll"><mml:mrow><mml:mi>L</mml:mi><mml:mi>e</mml:mi><mml:mi>v</mml:mi><mml:mi>e</mml:mi><mml:mi>l</mml:mi><mml:mspace width="thickmathspace"/><mml:mn>2</mml:mn><mml:mo>:</mml:mo><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mn>0</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:msub><mml:mi>&#x003c0;</mml:mi><mml:mn>00</mml:mn></mml:msub><mml:mo>+</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:msub><mml:mi>&#x003c0;</mml:mi><mml:mn>01</mml:mn></mml:msub><mml:mrow><mml:mo>(</mml:mo><mml:mi>P</mml:mi><mml:mi>a</mml:mi><mml:mi>r</mml:mi><mml:mi>e</mml:mi><mml:mi>n</mml:mi><mml:mi>t</mml:mi><mml:mi>a</mml:mi><mml:mi>l</mml:mi><mml:mspace width="thickmathspace"/><mml:mi>K</mml:mi><mml:mi>n</mml:mi><mml:mi>o</mml:mi><mml:mi>w</mml:mi><mml:mi>l</mml:mi><mml:mi>e</mml:mi><mml:mi>d</mml:mi><mml:mi>g</mml:mi><mml:mi>e</mml:mi><mml:mo>)</mml:mo></mml:mrow><mml:mo>]</mml:mo></mml:mrow><mml:mo>+</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:msub><mml:mi>u</mml:mi><mml:mrow><mml:mn>0</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>]</mml:mo></mml:mrow></mml:mrow></mml:math></disp-formula><disp-formula id="FD3"><label>(1c)</label><mml:math display="block" id="M3" overflow="scroll"><mml:mrow><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mn>1</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:msub><mml:mi>&#x003c0;</mml:mi><mml:mn>10</mml:mn></mml:msub><mml:mo>+</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:msub><mml:mi>u</mml:mi><mml:mrow><mml:mn>1</mml:mn><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>]</mml:mo></mml:mrow></mml:mrow></mml:math></disp-formula></p><p id="P21">At Level 1 (daily level, <xref ref-type="disp-formula" rid="FD1">equation 1a</xref>), youth <italic>i</italic>'s health outcomes on day <italic>t</italic> were modeled as a function of their daily intercept (B<sub>0</sub><italic><sub>i</sub></italic>), daily slope (B<sub>1</sub><italic><sub>i</sub></italic>), and residual variance (<italic>e<sub>ti</sub></italic><sub>.</sub>). The daily slope reflects changes in youth outcomes on days when parents have more knowledge than usual (within-person). At Level 2 (between person-level), the level 1 intercept (<xref ref-type="disp-formula" rid="FD2">equation 1b</xref>) was modeled as a function of the sample mean intercept (&#x003c0;<sub>00</sub>), and the effect of parental knowledge averaged across the days (&#x003c0;<sub>01</sub>), as well as random effects (<italic>u<sub>0i</sub></italic>). The level 1 slope (<xref ref-type="disp-formula" rid="FD3">equation 1c</xref>) was modeled as the sample average daily within-person effect (&#x003c0;<sub>10</sub>) and random effects (<italic>u<sub>1i</sub></italic>).<sup><xref ref-type="fn" rid="FN1">1</xref></sup></p><p id="P22">Lagged models were run to test the linkages between daily knowledge and the cortisol awaking response (CAR) on the following day. Lagged models were similar to the same-day models, however, the lagged models also included parental knowledge from the prior day as a predictor of CAR. Thus, lagged models test the effects of prior-day knowledge on the CAR, while controlling for same-day knowledge. Whereas same-day models allowed us to investigate the same-day linkages between knowledge and cortisol, lagged models allowed us to investigate the linkages between knowledge and next-day morning cortisol patterns.</p><p id="P23">We estimated two models for each of the health outcome variables. First, we tested the main effects of parental knowledge on youth's physical symptoms and HPA functioning. Second, we tested whether the links between knowledge and youth health outcomes were moderated by youth gender or age at both the between and within-person levels. Follow-up tests of the simple slopes were conducted when interaction terms were significant at <italic>p</italic> &#x0003c; .05 (<xref rid="R3" ref-type="bibr">Aiken &#x00026; West, 1991</xref>).</p><p id="P24">For significant effects, we calculated the percent change in the outcome variable as a result of a one unit increase in the predictor variable using the following equation: <disp-formula id="FD4"><mml:math display="block" id="M4" overflow="scroll"><mml:mrow><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mo>%</mml:mo><mml:mspace width="thickmathspace"/><mml:mi>c</mml:mi><mml:mi>h</mml:mi><mml:mi>a</mml:mi><mml:mi>n</mml:mi><mml:mi>g</mml:mi><mml:mi>e</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:mrow><mml:mo>[</mml:mo><mml:mi>exp</mml:mi><mml:mrow><mml:mo>(</mml:mo><mml:msub><mml:mi mathvariant="normal">B</mml:mi><mml:mrow><mml:mi>r</mml:mi><mml:mi>a</mml:mi><mml:mi>w</mml:mi></mml:mrow></mml:msub><mml:mo>)</mml:mo></mml:mrow><mml:mo>]</mml:mo></mml:mrow><mml:mo>&#x02212;</mml:mo><mml:mn>1</mml:mn><mml:mo>.</mml:mo></mml:mrow></mml:math></disp-formula></p><p id="P25">Similar to calculating effect sizes, calculating the percent change enabled us to ascertain the strength of these associations with the outcome variables (see <xref rid="R2" ref-type="bibr">Adam, Hawkley, Kudielka &#x00026; Caciaoppo, 2006</xref>).</p></sec></sec><sec sec-type="results" id="S9"><title>Results</title><sec id="S10"><title>Descriptive Statistics</title><p id="P26">Average parental knowledge was high (<italic>M</italic> = 3.35 on a 4-point scale), suggesting that parents were generally very knowledgeable about youth activities (<xref ref-type="table" rid="T1">Table 1</xref>). The intra-class correlation (ICC) for parental knowledge was .54, suggesting that a substantial amount of variance (46%) occurred within individuals across days. ICCs for cortisol levels and physical health symptoms ranged from .07 to .34, also indicating substantial day-to-day variation. There were no significant correlations between youth gender and either knowledge or the health measures, except for the CAR, which indicated that girls had a steeper rise in cortisol in the morning hours. Age was significantly negatively correlated with knowledge and positively linked to before dinner cortisol levels and the CAR.</p></sec><sec id="S11"><title>Parental Knowledge and Youth Health</title><p id="P27">As predicted, at the between-person level, when parents had higher average knowledge, youth reported lower bedtime cortisol levels (<xref ref-type="table" rid="T2">Table 2</xref> and <xref ref-type="fig" rid="F1">Figure 1</xref>). This coefficient, <italic>B</italic> = &#x02212;.12, is equivalent to an 11.3% percent change: For every one unit increase in parental knowledge (e.g., a change in one point on the knowledge scale) , there is a 11.3% decrease in bedtime cortisol levels (<xref rid="R2" ref-type="bibr">Adam et al., 2006</xref>). At the within-person level, controlling for average knowledge, on days when parents were more knowledgeable than usual, youth had lower before dinner cortisol than usual, <italic>B</italic> = &#x02212;.10. For every one unit increase in daily parental knowledge, there was a 9.5% decrease in before dinner cortisol levels. There were no other significant within-person associations.</p></sec><sec id="S12"><title>Moderation by Youth Age and Gender</title><p id="P28">A significant parental knowledge by youth age interaction predicted physical symptoms at the between-person level. Tests of the simple slopes (+ / &#x02212; 1 <italic>SD</italic>) confirmed that the links between average knowledge and youth physical health symptoms were significant for younger, <italic>B</italic> = &#x02212;.26, <italic>SE</italic> = .09, <italic>p</italic> &#x0003c; .01 but not older adolescents, <italic>B</italic> = &#x02212;.002, <italic>SE</italic> = .08, <italic>ns</italic> (<xref ref-type="table" rid="T3">Table 3</xref> and <xref ref-type="fig" rid="F2">Figure 2</xref>). For every one unit increase in average parental knowledge, there was a 23% decrease in physical symptoms for younger children. Contrary to our hypotheses, no other significant interactions involving youth age emerged, nor was there evidence of gender moderation (not shown).</p></sec></sec><sec sec-type="discussion" id="S13"><title>Discussion</title><p id="P29">High parental knowledge has been linked to a lower levels of a host of youth risky behaviors, ranging from delinquency and substance use to risky sexual behavior (<xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>). We built on this literature to document that parental knowledge may also be linked to youth's physical health and HPA functioning. Youth who reported that their parents were more knowledgeable about their experiences, on average, exhibited lower (more healthful) bedtime cortisol levels, and younger adolescents reported fewer physical health symptoms. Further, on days when parents were more knowledgeable than usual, youth also had lower levels of cortisol before dinner. The results contributed to the literature that links parental knowledge to youth risky behavior (<xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>) by extending analyses to youth physical health outcomes, including physical symptoms and HPA functioning. Our findings suggests that interventions aimed to improve parental knowledge may have benefits not only for behavioral health, but for physical health as well. We found no prior studies that tested links between parental knowledge and youth physical health. As such, although the results require replication, this study breaks new ground and suggests directions for future research and application.</p><p id="P30">Although it was beyond the scope of this study to identify underlying processes, there are several reasons why parental knowledge may be linked to healthful HPA functioning and fewer physical health symptoms. Parents who know about youth activities may be more aware of whether or not youth engage in healthful behaviors such as physical activity, eating well, and getting adequate rest (<xref rid="R9" ref-type="bibr">Cohen, 2004</xref>). In turn, they may be more likely to promote healthful behaviors in their children, with positive implications for youth's physical health and stress-related physiology (<xref rid="R8" ref-type="bibr">Buckley&#x00026; Schatzberg, 2005</xref>; <xref rid="R34" ref-type="bibr">Meerlo et al., 2002</xref>; <xref rid="R37" ref-type="bibr">Pederson &#x00026; Hoffman-Goetz, 2000</xref>; <xref rid="R45" ref-type="bibr">Traustad&#x000f3;ttir et al., 2005</xref>). Parents who are more knowledgeable also may know more about youth stresses and anxieties and thus can offer advice and support (<xref rid="R44" ref-type="bibr">Stattin &#x00026; Kerr, 2000</xref>; <xref rid="R29" ref-type="bibr">Lippold et al., 2013</xref>). As such, youth with knowledgeable parents may experience fewer stressors and their reactions to stressors may be tempered, resulting in more healthful HPA axis functioning as indexed by lower levels of salivary cortisol at the end of the day. As noted, future studies are needed to identity the processes underlying these associations, such as how parents&#x02019; knowledge may be linked to orchestration of their children's healthful behaviors and routines and the role of knowledge as a protective factor in youth's stress and coping. Such studies would further illuminate targets for interventions aimed to improve youth health.</p><p id="P31">Our study also built on prior work by assessing the implications of daily knowledge for youth's <italic>daily</italic> health. Analyses revealed a significant link at the within-individual level: On days when parents have more knowledge than usual, youth exhibited lower than usual cortisol levels before dinner. Such within-person effects are notable given that they rule out stable third variable explanations, whether measured or not (<xref rid="R4" ref-type="bibr">Almeida, 2005</xref>). Perhaps the period before dinner, when parents and youth have recently returned home from work or school, is a time when youth are especially inclined to process the day's stressful experiences and look to parents for support and advice. Thus, interventions may need to focus on ways to encourage parent-youth communication at the end of the school day. Consistent with this possibility, there was more variance at the within-person level for cortisol before dinner than at bedtime, which may help to account for the pattern of findings. The lack of within-person associations with physical health, bedtime cortisol, and next day CAR was surprising, given that there were substantial day-to-day fluctuations in parental knowledge and most of the youth health measures. It may be that average levels of knowledge reflect parental practices, such as promoting positive health behaviors, whose effects accumulate over days (<xref rid="R9" ref-type="bibr">Cohen, 2004</xref>; Umberson et al., 2014; <xref rid="R22" ref-type="bibr">Kitzman-Ulrich et al., 2010</xref>). Because the effects of promoting healthful behavior, such as eating a balanced diet, adequate physical activity, regular bedtimes, and adequate sleep accumulate over time, average, rather than daily levels of knowledge may be more closely linked to health symptoms. Average knowledge may also reflect a family climate of connectedness, such that youth feel a sense of security--that their parents will be available when they need them-- even if parents are less knowledgeable on a particular day.</p><p id="P32">Interestingly, although we found linkages between knowledge and evening and bedtime levels of cortisol, there were no significant linkages between knowledge and the CAR. Daily parental knowledge may have stronger effects on same-day cortisol levels because they are more proximal in time; next day effects may be too distal to detect effects given our measurement approach. Further, there is some evidence that the CAR is more endogenous and less likely to be affected by contextual factors than evening levels (<xref rid="R14" ref-type="bibr">Fries, Dettenborn, &#x00026; Kirschbaum, 2009</xref>). Therefore, even average levels of parental knowledge may have fewer linkages to morning rise than to other indicators of HPA functioning.</p><p id="P33">As predicted, the link between knowledge and physical health symptoms was moderated by age and was significant for younger but not older adolescents. These findings may reflect increased self-direction, including around health behaviors, as youth become older and issues of bedtime, food choice, and activity involvement become part of the personal domain of decision-making (<xref rid="R43" ref-type="bibr">Smetana, 2011</xref>). Thus, interventions aimed to increase parental knowledge may have stronger impacts on younger adolescents&#x02019; health. As noted research is needed to illuminate the processes underlying the links between parental knowledge and youth health, including the role of youth autonomy. In contrast, age moderation was not evident for salivary cortisol outcomes, however, suggesting that parental knowledge may be linked to HPA functioning across adolescence. There also was no evidence of gender moderation in face of mixed findings of gender differences in parental knowledge and cortisol (<xref rid="R15" ref-type="bibr">Hankin &#x00026; Abramson, 2001</xref>; <xref rid="R16" ref-type="bibr">Hardie, Moss, Vanyukov, Yao, &#x00026; Kirillovac, 2002</xref>). This may be due to our small sample size and findings must be replicated, but they are suggestive that parental knowledge is significant for the physical health of both girls and boys.</p><p id="P34">Our findings should be interpreted in light of this study's limitations. First, our correlational design does not allow for conclusions about direction of effects: parental knowledge may promote youth health, but it also may be that youth with better health are more likely to see their parents as more knowledgeable. Experimental studies that, for example, test the effects of interventions designed to promote parental knowledge, would provide evidence of its causal role in youth health. Further, the sample included youth with generally well-educated parents who were employed in one industry; thus, the findings require replication on other groups of youth. We also did not measure potential processes underlying parental knowledge&#x02014;health outcome linkages, a next important step in this line of research. Parental knowledge may reflect parents&#x02019; solicitation or behavioral control or youth disclosure (<xref rid="R38" ref-type="bibr">Racz &#x00026; McMahon, 2011</xref>) and its influence may be moderated by contextual factors such as the affective quality of the parent-child relationship, parental support of youth autonomy, or parenting style (<xref rid="R27" ref-type="bibr">Lippold et al, 2014</xref>), additional directions for future research. Further, traditional estimates of effect sizes do not apply to multi-level models (<xref rid="R17" ref-type="bibr">Holden, Kelley, &#x00026; Agarwal, 2008</xref>). Our estimates of the percent change in our outcome variables associated with a one-unit increase in knowledge were modest, especially for our cortisol models (ranging from 9.5 to 11 percent). Clearly other factors not measured here also influence youth cortisol levels. Finally, we relied on youth self-reports of parental knowledge. Parental reports of knowledge might yield a different pattern of effects (<xref rid="R30" ref-type="bibr">Lippold et al., 2011</xref>).</p><p id="P35">In the face of its limitations, this study provided several important contributions to our understanding of the role of parental knowledge in youth health. We focused on physical health, assessing the linkages between knowledge and youth physical health symptoms and cortisol. The consistency of results across indicators of physical health and cortisol is noteworthy and suggests that, beyond its documented links with youth behavioral adjustment, parental knowledge also has implications for youth's HPA functioning and physical health symptoms. We used a daily diary approach, asking youth to report on parental knowledge and health symptoms across eight days. Such approaches minimize recall bias and allow us to understand how both average and daily knowledge may be linked to youth physical health. We also moved beyond self-reports of health by including a biomarker of HPA axis functioning. We know little about parental behaviors that are linked to children's physical health, but our findings suggest parental knowledge may be one means by which parents impact youth physical well-being. At the most general level, they imply that interventions aimed to improve parental knowledge may have positive implications for adolescent physical health.</p></sec></body><back><ack id="S14"><title>Acknowledgements</title><p>This research was conducted as part of the Work, Family and Health Network (<ext-link ext-link-type="uri" xlink:href="http://www.WorkFamilyHealthNetwork.org">www.WorkFamilyHealthNetwork.org</ext-link>), which is funded by a cooperative agreement through the National Institutes of Health and the Centers for Disease Control and Prevention: <italic>Eunice Kennedy Shriver</italic> National Institute of Child Health and Human Development (Grant # U01HD051217, U01HD051218, U01HD051256, U01HD051276), National Institute on Aging (Grant # U01AG027669), Office of Behavioral and Science Sciences Research, and National Institute for Occupational Safety and Health (Grant # U01OH008788, U01HD059773). Grants from the William T. Grant Foundation, Alfred P Sloan Foundation, and the Administration for Children and Families have provided additional funding. The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official views of these institutes and offices. Special acknowledgement goes to Extramural Staff Science Collaborator, Rosalind Berkowitz King, Ph.D. and Lynne Casper, Ph.D. for design of the original Workplace, Family, Health and Well-Being Network Initiative. We also wish to express our gratitude to the worksites, employers, and employees who participated in this research and to Lauren Camuso for her assistance with this paper. Full acknowledgements: <ext-link ext-link-type="uri" xlink:href="http://www.kpchr.org/wfhn">http://www.kpchr.org/wfhn</ext-link></p></ack><fn-group><fn id="FN1"><label>1</label><p id="P36">Given the distribution of our physical symptoms variable, we also ran our physical symptoms model using a Poisson distribution in PROC GLIMMIX. We obtained the same results. 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Youth with higher average parental knowledge have lower levels of bedtime cortisol levels (1b). WP = within-person, daily level, BP = between-person, average level. Figures are based on +/&#x02212; 1 SD of knowledge. Cortisol values are presented in nmol/1.</p></caption><graphic xlink:href="nihms-742106-f0001"/></fig><fig id="F2" orientation="portrait" position="float"><label>Figure 2</label><caption><title>Youth age moderates the between-person (BP) associations of parental knowledge and youth physical health symptoms</title><p>These linkages were significant for younger (&#x02212;1 SD, approximately age 11) but not older youth(+ 1 SD, age 15.8). *p &#x0003c; .05.</p></caption><graphic xlink:href="nihms-742106-f0002"/></fig><table-wrap id="T1" position="float" orientation="landscape"><label>Table 1</label><caption><p>Means, Standard Deviations, Pearson Correlations and Intra-Class Correlations of Study Variables</p></caption><table frame="below" rules="none"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th align="left" valign="top" rowspan="1" colspan="1"/><th align="center" valign="top" rowspan="1" colspan="1">BP Mean</th><th align="center" valign="top" rowspan="1" colspan="1">BP SD</th><th align="center" valign="top" rowspan="1" colspan="1">WP SD</th><th align="center" valign="top" rowspan="1" colspan="1">1.</th><th align="center" valign="top" rowspan="1" colspan="1">2.</th><th align="left" valign="top" rowspan="1" colspan="1">3.</th><th align="center" valign="top" rowspan="1" colspan="1">4.</th><th align="left" valign="top" rowspan="1" colspan="1">5.</th><th align="center" valign="top" rowspan="1" colspan="1">6.</th><th align="right" valign="top" rowspan="1" colspan="1">7.</th><th align="left" valign="top" rowspan="1" colspan="1">8.</th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th align="left" valign="top" rowspan="1" colspan="1"/><th colspan="11" align="center" valign="top" rowspan="1"><hr/></th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">1.</td><td align="left" valign="top" rowspan="1" colspan="1">Parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">3.35</td><td align="center" valign="top" rowspan="1" colspan="1">.62</td><td align="center" valign="top" rowspan="1" colspan="1">.77</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">2.</td><td align="left" valign="top" rowspan="1" colspan="1">Before dinner cortisol levels</td><td align="center" valign="top" rowspan="1" colspan="1">2.34</td><td align="center" valign="top" rowspan="1" colspan="1">2.29</td><td align="center" valign="top" rowspan="1" colspan="1">2.92</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.11</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">3.</td><td align="left" valign="top" rowspan="1" colspan="1">Bedtime cortisol levels</td><td align="center" valign="top" rowspan="1" colspan="1">1.55</td><td align="center" valign="top" rowspan="1" colspan="1">1.54</td><td align="center" valign="top" rowspan="1" colspan="1">1.94</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.29**</td><td align="center" valign="top" rowspan="1" colspan="1">.60***</td><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">4.</td><td align="left" valign="top" rowspan="1" colspan="1">Dinner to bedtime slope</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.39</td><td align="center" valign="top" rowspan="1" colspan="1">1.80</td><td align="center" valign="top" rowspan="1" colspan="1">3.06</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.23**</td><td align="left" valign="top" rowspan="1" colspan="1">.31*</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">5.</td><td align="left" valign="top" rowspan="1" colspan="1">Cortisol awakening response</td><td align="center" valign="top" rowspan="1" colspan="1">.28</td><td align="center" valign="top" rowspan="1" colspan="1">.42</td><td align="center" valign="top" rowspan="1" colspan="1">.65</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.14</td><td align="center" valign="top" rowspan="1" colspan="1">.25*</td><td align="left" valign="top" rowspan="1" colspan="1">.11</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;0.08</td><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">6.</td><td align="left" valign="top" rowspan="1" colspan="1">Physical symptoms</td><td align="center" valign="top" rowspan="1" colspan="1">.47</td><td align="center" valign="top" rowspan="1" colspan="1">.47</td><td align="center" valign="top" rowspan="1" colspan="1">.78</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.20*</td><td align="center" valign="top" rowspan="1" colspan="1">.00</td><td align="left" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02212;.07</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">7.</td><td align="left" valign="top" rowspan="1" colspan="1">Youth age</td><td align="center" valign="top" rowspan="1" colspan="1">13.39</td><td align="center" valign="top" rowspan="1" colspan="1">2.4</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.21*</td><td align="center" valign="top" rowspan="1" colspan="1">.18*</td><td align="left" valign="top" rowspan="1" colspan="1">.15</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07</td><td align="left" valign="top" rowspan="1" colspan="1">.36**</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="right" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">8.</td><td align="left" valign="top" rowspan="1" colspan="1">Youth gender</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">.04</td><td align="center" valign="top" rowspan="1" colspan="1">.06</td><td align="left" valign="top" rowspan="1" colspan="1">.07</td><td align="center" valign="top" rowspan="1" colspan="1">.02</td><td align="left" valign="top" rowspan="1" colspan="1">.27**</td><td align="center" valign="top" rowspan="1" colspan="1">.16</td><td align="right" valign="top" rowspan="1" colspan="1">.16</td><td align="left" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1">ICC</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">.54</td><td align="center" valign="top" rowspan="1" colspan="1">.34</td><td align="left" valign="top" rowspan="1" colspan="1">.29</td><td align="center" valign="top" rowspan="1" colspan="1">.07</td><td align="left" valign="top" rowspan="1" colspan="1">.18</td><td align="center" valign="top" rowspan="1" colspan="1">.25</td><td align="right" valign="top" rowspan="1" colspan="1">-----</td><td align="left" valign="top" rowspan="1" colspan="1">-----</td></tr></tbody></table><table-wrap-foot><fn id="TFN1"><label>*</label><p id="P37"><italic>p</italic> &#x0003c; .05.</p></fn><fn id="TFN2"><label>**</label><p id="P38"><italic>p</italic> &#x0003c; .01.</p></fn><fn id="TFN3"><label>***</label><p id="P39"><italic>p</italic> &#x0003c; .001</p></fn><p><italic>Note.</italic> BP indicates between-person, average level. WP indicates within-person, daily level. Correlations are based on cross-day indices of daily measures. ICC indicates intra-class correlations of study variables.</p></table-wrap-foot></table-wrap><table-wrap id="T2" position="float" orientation="landscape"><label>Table 2</label><caption><p>Estimates (and Standard Errors) for Links between Parental Knowledge and Youth Physical Health Symptoms and HPA Functioning</p></caption><table frame="below" rules="none"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th colspan="2" align="center" valign="top" rowspan="1">Physical Health Symptoms</th><th colspan="2" align="center" valign="top" rowspan="1">Before Dinner Level of Cortisol</th><th colspan="2" align="center" valign="top" rowspan="1">Bedtime Level of Cortisol</th><th colspan="2" align="center" valign="top" rowspan="1">Dinner to Bedtime Slope</th><th colspan="2" align="center" valign="top" rowspan="1">Cortisol Awakening Response</th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="center" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="center" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th colspan="10" align="center" valign="top" rowspan="1"><hr/></th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Fixed effects</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">BP parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.10</td><td align="left" valign="top" rowspan="1" colspan="1">(0.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.12*</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="center" valign="top" rowspan="1" colspan="1">(.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">WP parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="left" valign="top" rowspan="1" colspan="1">(0.04)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.10*</td><td align="left" valign="top" rowspan="1" colspan="1">(.05)</td><td align="center" valign="top" rowspan="1" colspan="1">.06</td><td align="left" valign="top" rowspan="1" colspan="1">(.05)</td><td align="center" valign="top" rowspan="1" colspan="1">.13</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07</td><td align="center" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Prior-day parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">---</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Youth age</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.03*</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.01)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Youth gender</td><td align="center" valign="top" rowspan="1" colspan="1">.14*</td><td align="left" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">.11*</td><td align="center" valign="top" rowspan="1" colspan="1">(.07)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Parent education</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07</td><td align="left" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="center" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Race</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.10</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.07)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Daily stressors</td><td align="center" valign="top" rowspan="1" colspan="1">.51</td><td align="left" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">.16</td><td align="left" valign="top" rowspan="1" colspan="1">(.10)</td><td align="center" valign="top" rowspan="1" colspan="1">.11</td><td align="left" valign="top" rowspan="1" colspan="1">(.10)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="center" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">.09</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">BP time of sample collection</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.03*</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.03</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07*</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">WP time of sample collection</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.13*</td><td align="center" valign="top" rowspan="1" colspan="1">(.02)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Medication use</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.14</td><td align="left" valign="top" rowspan="1" colspan="1">(.14)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.10)</td><td align="center" valign="top" rowspan="1" colspan="1">.16</td><td align="center" valign="top" rowspan="1" colspan="1">(.12)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.08</td><td align="center" valign="top" rowspan="1" colspan="1">(.11)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Random effects</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="left" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Intercept</td><td align="center" valign="top" rowspan="1" colspan="1">.20**</td><td align="left" valign="top" rowspan="1" colspan="1">(.04)</td><td align="center" valign="top" rowspan="1" colspan="1">.09**</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.06**</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.00</td><td align="center" valign="top" rowspan="1" colspan="1">.03***</td><td align="center" valign="top" rowspan="1" colspan="1">.04</td><td align="center" valign="top" rowspan="1" colspan="1">(.02)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Residual</td><td align="center" valign="top" rowspan="1" colspan="1">.63**</td><td align="left" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">.20**</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.19**</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.45**</td><td align="center" valign="top" rowspan="1" colspan="1">.05***</td><td align="center" valign="top" rowspan="1" colspan="1">.30</td><td align="center" valign="top" rowspan="1" colspan="1">(.02)</td></tr></tbody></table><table-wrap-foot><p><italic>p</italic> &#x02264; .05</p><fn id="TFN4"><label>**</label><p id="P40"><italic>p</italic> &#x0003c; .01</p></fn><fn id="TFN5"><label>***</label><p id="P41"><italic>p</italic> &#x0003c; .001</p></fn><p><italic>Note</italic> : BP= average, between-person effects; WP= daily, within-person effects.</p></table-wrap-foot></table-wrap><table-wrap id="T3" position="float" orientation="landscape"><label>Table 3</label><caption><p>Linkages Between Parental Knowledge and Youth Health: Moderation by Youth Age</p></caption><table frame="below" rules="none"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th colspan="2" align="center" valign="top" rowspan="1">Physical Health Symptoms</th><th colspan="2" align="center" valign="top" rowspan="1">Before Dinner Level of Cortisol</th><th colspan="2" align="center" valign="top" rowspan="1">Bedtime Level of Cortisol</th><th colspan="2" align="center" valign="top" rowspan="1">Dinner to Bedtime Slope</th><th colspan="2" align="center" valign="top" rowspan="1">Cortisol Awakening Response</th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="center" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th><th align="center" valign="top" rowspan="1" colspan="1">Est</th><th align="left" valign="top" rowspan="1" colspan="1">(<italic>SE</italic>)</th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th colspan="10" align="center" valign="top" rowspan="1"><hr/></th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">BP parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.13</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.10)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.10</td><td align="center" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.06</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">WP parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.05)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.05)</td><td align="center" valign="top" rowspan="1" colspan="1">.06</td><td align="left" valign="top" rowspan="1" colspan="1">(.04)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.21</td><td align="center" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Prior-day parental knowledge</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="left" valign="top" rowspan="1" colspan="1">(.06)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Youth age</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.03*</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.05*</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Youth gender</td><td align="center" valign="top" rowspan="1" colspan="1">.14*</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">.12</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Parent education</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.10</td><td align="left" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.08</td><td align="left" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.06</td><td align="left" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="center" valign="top" rowspan="1" colspan="1">(.09)</td><td align="center" valign="top" rowspan="1" colspan="1">.00</td><td align="left" valign="top" rowspan="1" colspan="1">.08</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Race</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.11</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.08)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Daily stressors</td><td align="center" valign="top" rowspan="1" colspan="1">.51</td><td align="left" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">.18</td><td align="left" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.07)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="center" valign="top" rowspan="1" colspan="1">(.11)</td><td align="center" valign="top" rowspan="1" colspan="1">.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.09)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">BP time of sample collection</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.03</td><td align="center" valign="top" rowspan="1" colspan="1">(.04)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.07*</td><td align="left" valign="top" rowspan="1" colspan="1">(.03)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">WP time of sample collection</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.02</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.01)</td><td align="center" valign="top" rowspan="1" colspan="1">.05</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.13*</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Medication use</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.16</td><td align="left" valign="top" rowspan="1" colspan="1">(.12)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.09</td><td align="left" valign="top" rowspan="1" colspan="1">(.10)</td><td align="center" valign="top" rowspan="1" colspan="1">.16</td><td align="center" valign="top" rowspan="1" colspan="1">(.12)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.08</td><td align="left" valign="top" rowspan="1" colspan="1">(.11)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">BP knowledge &#x000d7; age</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.06*</td><td align="left" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.03</td><td align="left" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.04</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">WP knowledge &#x000d7; age</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td><td align="center" valign="top" rowspan="1" colspan="1">.01</td><td align="center" valign="top" rowspan="1" colspan="1">(.03)</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Prior-day knowledge &#x000d7; age</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="left" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02212;.01</td><td align="left" valign="top" rowspan="1" colspan="1">(.02)</td></tr></tbody></table><table-wrap-foot><p><italic>p</italic> &#x02264; .05.</p><p>** <italic>p</italic> &#x0003c; .01.</p><p>*** <italic>p</italic> &#x0003c; .001</p><p>Note: BP= average, between-person effects; WP= daily, within-person effects. Models also include random effects for the intercept (not shown).</p></table-wrap-foot></table-wrap></floats-group></article>