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Antibodies to toluene diisocyanate in an environmentally exposed population.

Published Date:

Oct 1998

Source:

Environ Health Perspect. 106(10):665-666.

[PDF-639.99 KB]

Details:

Alternative Title:

Environ Health Perspect

Personal Author:

Orloff, K G ; Batts-Osborne, D ; Kilgus, T ; Metcalf, S ; Cooper, M ;

Description:

Residents living near a polyurethane foam manufacturing facility expressed concern to health officials over chemical emissions from the plant. Environmental monitoring of ambient air near the plant indicated the presence of toluene diisocyanate (TDI), which was used in foam production. Health officials collected blood samples from 113 residents and analyzed the blood sera for antibodies to TDI and related diisocyanates. Ten of the 113 residents (9%) had elevated levels of IgG or IgE antibodies specific for one or more diisocyanates. Exposure histories were taken from antibody-positive individuals to identify possible occupational exposure to TDI or the use of diisocyanate-containing consumer products. Exposure to TDI in ambient air may be responsible for the positive antibody responses detected in some residents of the community.

Subject:

[+]

Document Type:

Journal Article

Place as Subject:

North Carolina

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

File Type:

Supporting Files:

	license.txt	text/plain
	envhper00533-0083.gif	image/gif
	envhper00533-0083.nxml	text/plain
	envhper00533-0083.tif	image/tiff
	envhper00533-0083.txt	text/plain
	envhper00533-0084.gif	image/gif
	envhper00533-0084.tif	image/tiff

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