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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article"><?properties manuscript?><front><journal-meta><journal-id journal-id-type="nlm-journal-id">7603486</journal-id><journal-id journal-id-type="pubmed-jr-id">244</journal-id><journal-id journal-id-type="nlm-ta">Addict Behav</journal-id><journal-id journal-id-type="iso-abbrev">Addict Behav</journal-id><journal-title-group><journal-title>Addictive behaviors</journal-title></journal-title-group><issn pub-type="ppub">0306-4603</issn><issn pub-type="epub">1873-6327</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25658771</article-id><article-id pub-id-type="pmc">4700509</article-id><article-id pub-id-type="doi">10.1016/j.addbeh.2015.01.023</article-id><article-id pub-id-type="manuscript">HHSPA745633</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The relation between tobacco taxes and youth and young adult smoking: What happened following the 2009 U.S. federal tax increase on cigarettes?</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>van Hasselt</surname><given-names>Martijn</given-names></name><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Kruger</surname><given-names>Judy</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Han</surname><given-names>Beth</given-names></name><xref ref-type="aff" rid="A3">c</xref></contrib><contrib contrib-type="author"><name><surname>Caraballo</surname><given-names>Ralph S.</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Penne</surname><given-names>Michael A.</given-names></name><xref ref-type="aff" rid="A4">d</xref></contrib><contrib contrib-type="author"><name><surname>Loomis</surname><given-names>Brett</given-names></name><xref ref-type="aff" rid="A4">d</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Gfroerer</surname><given-names>Joseph C.</given-names></name><xref ref-type="aff" rid="A3">c</xref></contrib></contrib-group><aff id="A1"><label>a</label>Department of Economics, The University of North Carolina at Greensboro, PO Box 26170, Greensboro, NC 27402, United States</aff><aff id="A2"><label>b</label>Office on Smoking and Health, National Center for Chronic Disease Prevention &#x00026; Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, M/SK-50, Atlanta, GA 30341, United States</aff><aff id="A3"><label>c</label>Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration, 1 Choke Cherry Road, Rockville, MD 20857, United States</aff><aff id="A4"><label>d</label>RTI International, 3040 E. Cornwallis Road, Research Triangle Park, NC 27709, United States</aff><author-notes><corresp id="cor1"><label>*</label>Corresponding author. <email>loomis@rti.org</email> (B. Loomis)</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>18</day><month>12</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>19</day><month>1</month><year>2015</year></pub-date><pub-date pub-type="ppub"><month>6</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>6</month><year>2016</year></pub-date><volume>45</volume><fpage>104</fpage><lpage>109</lpage><!--elocation-id from pubmed: 10.1016/j.addbeh.2015.01.023--><abstract><sec id="S1"><title>Background</title><p id="P1">On April 1, 2009, the federal government raised cigarette taxes from $0.39 to $1.01 per pack. This study examines the impact of this increase on a range of smoking behaviors among youth aged 12 to 17 and young adults aged 18 to 25.</p></sec><sec id="S2"><title>Methods</title><p id="P2">Data from the 2002&#x02013;2011 National Survey on Drug Use and Health (NSDUH) were used to estimate the impact of the tax increase on five smoking outcomes: (1) past year smoking initiation, (2) past-month smoking, (3) past year smoking cessation, (4) number of days cigarettes were smoked during the past month, and (5) average number of cigarettes smoked per day. Each model included individual and state-level covariates and other tobacco control policies that coincided with the tax increase. We examined the impact overall and by race and gender.</p></sec><sec id="S3"><title>Results</title><p id="P3">The odds of smoking initiation decreased for youth after the tax increase (odds ratio (OR) = 0.83, p &#x0003c; 0.0001). The odds of past-month smoking also decreased (youth: OR = 0.83, p &#x0003c; 0.0001; young adults: OR = 0.92, p &#x0003c; 0.0001), but the odds of smoking cessation remained unchanged. Current smokers smoked on fewer days (youth: coefficient = &#x02212;0.97, p = 0.0001; young adults: coefficient = &#x02212;0.84, p &#x0003c; 0.0001) and smoked fewer cigarettes per day after the tax increase (youth: coefficient = &#x02212;1.02, p = 0.0011; young adults: coefficient = &#x02212;0.92, p &#x0003c; 0.0001).</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">The 2009 federal cigarette tax increase was associated with a substantial reduction in smoking among youths and young adults. The impact of the tax increase varied across male, female, white and black subpopulations.</p></sec></abstract><kwd-group><kwd>Tobacco</kwd><kwd>Youth smoking</kwd><kwd>Young adult smoking</kwd><kwd>Tax</kwd></kwd-group></article-meta></front><body><sec sec-type="intro" id="S5"><title>1. Introduction</title><p id="P5">Tobacco use remains the leading preventable cause of death and disease in the United States (<xref rid="R35" ref-type="bibr">US DHHS, 2014</xref>). Data from the National Survey on Drug Use and Health (NSDUH) show that among youths aged 12 to 17 who had not smoked cigarettes prior to the past year (i.e., youths at risk for initiation), the incidence rate in 2012 was 4.8%. The prevalence of current cigarette smoking was 31.8% among young adults aged 18 to 25 (<xref rid="R26" ref-type="bibr">SAMHSA, 2013a</xref>). Both the rate of youth initiation to cigarette smoking and the prevalence of current smoking among young adults are well above the goals set by the U.S. Department of Health and Human Services in its Healthy People 2020 objectives (<xref rid="R33" ref-type="bibr">US DHHS, 2012a</xref>).</p><p id="P6">One of the most effective policies for reducing tobacco use is to increase the price of tobacco products, which is most commonly achieved by increasing state and federal excise taxes (<xref rid="R14" ref-type="bibr">Guide to Community Preventive Services, 2012</xref>). Several recent systematic reviews have found that higher cigarette prices lead to a reduction in smoking prevalence and intensity among youth and young adults (<xref rid="R2" ref-type="bibr">Bader, Boisclair, &#x00026; Ferrence, 2011</xref>; <xref rid="R5" ref-type="bibr">Chaloupka, Straif, &#x00026; Leon, 2011</xref>; <xref rid="R17" ref-type="bibr">IARC, 2011</xref>; <xref rid="R21" ref-type="bibr">Rice, Godfrey, Slack, Sowden, &#x00026; Worthy, 2009</xref>). <xref rid="R29" ref-type="bibr">Tauras (2005)</xref> found that, among young adults, an increase in the price of cigarettes led to transitions from daily smoking to no smoking, from moderate daily to light daily smoking, and from heavy daily smoking to moderate daily smoking. Several studies also conclude that higher prices resulting from higher taxes increased the number of quit attempts and the probability of successful cessation among youth and young adults (<xref rid="R8" ref-type="bibr">DeCicca, Kenkel, &#x00026; Mathios, 2008</xref>; <xref rid="R28" ref-type="bibr">Tauras, 2004</xref>; <xref rid="R30" ref-type="bibr">Tauras &#x00026; Chaloupka, 2001</xref>; <xref rid="R34" ref-type="bibr">US DHHS, 2012b</xref>; <xref rid="R38" ref-type="bibr">Zhang, Cohen, Ferrence, &#x00026; Rehm, 2006</xref>). Evidence suggests that youth and young adults are more sensitive to cigarette price and tax increases than adults (<xref rid="R5" ref-type="bibr">Chaloupka, 2001</xref>; <xref rid="R6" ref-type="bibr">Chaloupka et al., 2011</xref>; <xref rid="R7" ref-type="bibr">Chaloupka &#x00026; Wechsler, 1997</xref>; <xref rid="R10" ref-type="bibr">Farrelly &#x00026; Bray, 1998</xref>; <xref rid="R34" ref-type="bibr">US DHHS, 2012b</xref>). While higher taxes and prices may not altogether prevent young adolescents from experimenting with cigarettes, regular uptake of smoking typically also occurs at younger ages. Higher taxes therefore do have the potential to reduce smoking rates in the longer term (<xref rid="R22" ref-type="bibr">Ross &#x00026; Chaloupka, 2003</xref>).</p><p id="P7">This is the first study to examine changes in youth and young adult smoking behavior before and after the passage of the Children's Health Insurance Program Reauthorization Act of 2009, which raised the federal excise tax on a pack of cigarettes from $0.39 to $1.01 per pack, an increase of 158% (<xref rid="R13" ref-type="bibr">GPO, 2009</xref>). This represented the largest increase in U.S. federal excise taxes to date. As a result, cigarette prices jumped by 9.4% between March and April of 2009 (<xref rid="R36" ref-type="bibr">U.S. Department of Labor, 2009</xref>). The federal tax increase was also the only major tobacco control policy that affected smokers across the U.S. between 2008 and 2009. During this period, average state-level excise taxes on cigarettes remained more or less the same (<xref rid="R3" ref-type="bibr">CDC, 2009</xref>), and no other tobacco control policies were implemented uniformly across states.</p><p id="P8">The objective of our study was to estimate the effect of the federal cigarette tax increase on a wide range of smoking behaviors, including: (1) cigarette smoking initiation, (2) the prevalence of current cigarette use, (3) the number of days cigarettes were smoked among current smokers, (4) the average number of cigarettes smoked per day among current smokers, and (5) smoking cessation. We estimated the effect of the tax on youths aged 12&#x02013;17 and young adults aged 18&#x02013;25, by sex and race/ethnicity.</p></sec><sec sec-type="methods" id="S6"><title>2. Methods</title><sec id="S7"><title>2.1. Sample</title><p id="P9">The National Survey on Drug Use and Health (NSDUH) was used to examine the smoking behavior of youth and young adults from 2002 to 2011. NSDUH is an annual cross-sectional, national- and state-based survey on the use of tobacco products, alcohol, illicit drugs, and mental health status among the U.S. civilian, non-institutionalized population aged 12 or older (<xref rid="R26" ref-type="bibr">SAMHSA, 2013a</xref>). The survey has been conducted since 1971 and collects data quarterly through face-to-face interviews. NSDUH employs a state-based design with an independent probability sample within each state and the District of Columbia. This study used data from the 2002&#x02013;2011 NSDUH. Data prior to 2002 were not used because of the methodological changes introduced to the survey design in 2002, which affected respondent reporting of substance use (<xref rid="R18" ref-type="bibr">Kennet &#x00026; Gfroerer, 2005</xref>). Annual sample sizes are around 3600 for each of the eight states with the largest populations and around 900 for each of the remaining states and the District of Columbia. Youth and young adults were oversampled to achieve roughly equal numbers of respondents aged 12 to 17, 18 to 25, and 26 or older each year. This corresponds to annual sample sizes of about 1200 for each age group in large states and 300 per age group in small states. The percentage of eligible households that completed the initial screening was 90.7% in 2002 and declined to 87.0% in 2011. Interview response rates among youth and young adults were 90.0% and 85.2%, respectively, in 2002, and declined somewhat to 85.0% and 80.5%, respectively, in 2011. The 2002&#x02013;2011 study sample contained data on 226,315 youths and 226,228 young adults.</p></sec><sec id="S8"><title>2.2. Smoking measures</title><p id="P10">Cigarette smoking was assessed using five NSDUH indicators. The first indicator was <italic>initiation of cigarette smoking</italic> which is defined as having smoked the first lifetime cigarette during the 12 months before the survey interview. The measure is not defined for those who had a first lifetime cigarette more than 12 months before the survey interview. The second indicator was <italic>past-month cigarette smoking</italic> which is defined as having smoked all or part of a cigarette during the 30 days before the interview. This measure is defined for all respondents. The third indicator was <italic>smoking cessation</italic> which is defined as ever having smoked daily and smoked during the period 13 to 24 months ago, but not having smoked during the past 12 months. This measure is defined only for those who reported having been a daily smoker (i.e., having smoked 30 consecutive days) at some point in their lifetime and who reported smoking during the 13 to 24 months before the survey interview. The fourth indicator was a quantity measure among past-month smokers, in terms of the <italic>number of days smoked during the past month</italic>. The fifth indicator was the <italic>number of cigarettes</italic> smoked among past-month smokers on a typical day during the past month.</p></sec><sec id="S9"><title>2.3. Individual and state-level characteristics</title><p id="P11">In the statistical models for youth and young adults we controlled for the following set of respondent characteristics: sex, race/ethnicity, age, presence of parents in the household, birthplace (U.S. or not), household income, county type (e.g., metropolitan), religious service attendance, importance of religion, school enrollment, privacy during the survey interview, attitudes toward risky behavior, frequency of seatbelt use, and having moved 2 or more times during the past 5 years. In the models for youth, we also included two control variables measuring the perception of parents' attitude toward smoking one or more packs of cigarettes per day and perceived risk of smoking. In the models for young adults we included control variables for pregnancy, education, employment status, and health insurance status.</p><p id="P12">Several state-level covariates were used to account for differences in tobacco control policies and antismoking sentiment across states. State excise taxes on a pack of 20 cigarettes were obtained from the Tax Burden on Tobacco (<xref rid="R19" ref-type="bibr">Orzechowski &#x00026; Walker, 2012</xref>), which contains annual averages that were converted to quarterly numbers through linear interpolation. Quarterly indices for the presence of a smoke-free law in bars, restaurants, and private workplaces as covariates were also included. These were collected from the ImpacTeen project (<xref rid="R16" ref-type="bibr">ImpacTeen, 2013</xref>) and CDC's State Tobacco Activities Tracking and Evaluation (STATE) system (<xref rid="R4" ref-type="bibr">CDC, 2013</xref>). The values that each index assumed were &#x0201c;no restrictions,&#x0201d; &#x0201c;some restrictions,&#x0201d; and &#x0201c;complete smoking ban.&#x0201d;</p><p id="P13">An annual measure of the lack of compliance with laws prohibiting the sale of tobacco products to individuals younger than 18 was also included. Following the Synar Amendment of 1992, states were required to enact and enforce such laws and conduct annual, unannounced inspections of tobacco sales outlets (<xref rid="R24" ref-type="bibr">SAMHSA, 2011a</xref>; <xref rid="R34" ref-type="bibr">US DHHS, 2012b</xref>). The variable used in the analysis is the percentage of retailers that violate youth tobacco access laws, as reported by each state (<xref rid="R27" ref-type="bibr">SAMHSA, 2013b</xref>). The violation rate is expected to have limited explanatory power, because sale restrictions do not apply to young adults, and youth also rely on social sources (e.g., friends and family) to obtain cigarettes (<xref rid="R1" ref-type="bibr">Altman, Wheelis, McFarlane, Lee, &#x00026; Fortmann, 1999</xref>; <xref rid="R9" ref-type="bibr">DiFranza &#x00026; Coleman, 2001</xref>; <xref rid="R12" ref-type="bibr">Forster et al., 1998</xref>). However, we included the variable as a proxy for antismoking sentiment in a state.</p><p id="P14">We included quarterly per capita tobacco control funding, obtained from CDC's STATE system. To account for potential delayed effects of this funding, we calculated a discounted cumulative amount of funding for each quarter, which included the current quarter and the previous seven quarters, where past funding amounts were discounted at a quarterly rate of 25% (<xref rid="R11" ref-type="bibr">Farrelly, Pechacek, Thomas, &#x00026; Nelson, 2008</xref>). The final state-level covariate used in the model is a NSDUH estimate of smoking prevalence by quarter. This allowed us to control for the general downward trend in smoking that may have affected smoking among youth and young adults independently of the tax change. Additionally, this variable helped account for differences between states in general attitudes toward smoking. We used the smoking prevalence among 18- to 25-year-olds in the models for youth and the smoking prevalence among 26- to 49-year-olds in the models for young adults.</p><p id="P15">Before the analysis could proceed, appropriate values of the state-level variables had to be assigned to or linked with each individual record in NSDUH. Because the smoking measures relate to different time periods (e.g., past month, past 12 months), the assignment mechanism varied across the different outcome analyses. For the initiation indicator, we distinguished between those who initiated and those who did not. For those who initiated smoking, the month and year of initiation were known, so that we could assign values of the state-level covariates from the corresponding quarter. For individuals who did not initiate smoking, we calculated a &#x0201c;look-back date&#x0201d; of 45 days prior to the survey interview and assigned values of state-level variables from the quarter that contained the look-back date. Thus, for those not initiating, values were chosen from either the interview quarter or one quarter prior.</p><p id="P16">A similar approach was followed for the cessation outcome. For respondents who quit smoking 13 to 24 months before the interview date, the month and quarter of quitting were known and we assigned values of the state-level variables from the corresponding quarter. For respondents who did not quit smoking, we calculated a look-back date of 410 days (=365 + 45) before the survey interview and assigned values of the state-level variables from the quarter that contained the look-back date. Finally, the past-month smoking indicator and smoking intensity outcomes (days and cigarettes per day) refer to the 30 days before the survey interview. For these outcomes, we assigned to these individuals the values of the state-level covariates from the quarter that contained the majority of that 30-day period. Thus, in these analyses we assigned values of state-level covariates from either the interview quarter or one quarter prior (if the interview date fell within 15 days of the start of a quarter).</p></sec><sec id="S10"><title>2.4. Statistical analysis</title><p id="P17">Data were analyzed using SAS-Callable SUDAAN&#x000ae;(<xref rid="R23" ref-type="bibr">RTI International, 2012</xref>) to account for NSDUH's complex survey design and sampling weights. Smoking behavior was analyzed separately for youth and young adults, and the male, female, black and white populations within those age groups to examine potential differences in the response to the increase in the federal excise tax. Before estimation, all explanatory variables measured in dollars were adjusted for inflation using the Bureau of Labor Statistics' Consumer Price Index (<xref rid="R37" ref-type="bibr">U.S. Department of Labor, 2013</xref>). To adjust for missing data, an &#x02018;unknown&#x02019; category was added for unordered, categorical variables. Missing values of ordered or continuous variables were imputed (<xref rid="R25" ref-type="bibr">SAMHSA, 2011b</xref>). Regression coefficients and odds ratios (ORs) were estimated using Generalized Estimating Equations with Taylor linearization to calculate standard errors and confidence intervals (CIs).</p><p id="P18">The statistical models used to estimate the impact of the April 1, 2009, federal tax increase on each of the examined outcomes were pre-post regression models. They included as covariates the individual and state-level characteristics discussed before, as well as a post-period indicator (equal to 0 before April 1, 2009, and equal to 1 thereafter). The value of the indicator, corresponding to the reference period of the smoking outcome, was linked to the NSDUH record following the same procedure described above. For the binary outcomes (smoking initiation, current smoking, and cessation), we used a logistic regression model. For the smoking intensity outcomes (smoking days and cigarettes per day) of current smokers, we used a linear regression model. The analysis for smoking days was based on the sample of all current smokers, whereas the analysis for cigarettes per day was conducted separately for daily and nondaily smokers.</p></sec></sec><sec sec-type="results" id="S11"><title>3. Results</title><sec id="S12"><title>3.1. Descriptive statistics</title><p id="P19"><xref ref-type="table" rid="T1">Table 1</xref> contains the average rates of smoking initiation, past-month smoking and smoking cessation before and after the April 1, 2009 federal tax increase. Rates are shown separately for youth aged 12&#x02013;17, young adults aged 18&#x02013;25, and four subgroups. <xref ref-type="table" rid="T1">Table 1</xref> also shows, for current smokers, the number of days smoked during the past month and the number of cigarettes consumed per day of smoking.</p><p id="P20">Smoking initiation rates among youth and young adults were lower after the April 1 2009 tax increase compared to before the federal tax increase. The same was true for past-month cigarette use. The cessation rate among youth was lower after the tax increase, compared to before, whereas for young adults the rate was slightly higher. Among youth and young adult current smokers, the number of days smoked (during the past month) and the number of cigarettes smoked per day were lower after the tax increase, but compared to the averages before the tax increase, the reductions were marginal.</p></sec><sec id="S13"><title>3.2. Initiation, past-month use and cessation</title><p id="P21"><xref ref-type="table" rid="T2">Table 2</xref> shows the odds ratios (ORs) for the post-period indicator, estimated from the logistic regression models for smoking initiation, past-month cigarette use and smoking cessation. The OR represents the odds of the outcome occurring after April 1, 2009 relative to the odds of it occurring before April 1, 2009. ORs less than one indicate that, the outcome was less likely after compared to before the federal tax increase, controlling for individual and state-level characteristics.</p><p id="P22">For youth, the tax increase was associated with a reduction in the odds of smoking initiation (OR = 0.83, p &#x0003c; 0.0001). A similar result was found for the male, female, and white youth populations, but not for black youth. Initiation among young adults overall was not affected (OR = 0.91, p = 0.0532), but the odds of initiating were lower for white young adults after the tax increase (OR = 0.88, p = 0.0268).</p><p id="P23">The odds of past-month cigarette use were lower after the tax increase for the youth population overall (OR = 0.83, p &#x0003c; 0.0001) and three out of four subpopulations (male, female, and white, ORs = 0.75&#x02013;0.92, p &#x0003c; 0.05). For young adults, the odds of past-month cigarette use were also lower after the tax increase (OR=0.92, p &#x0003c; 0.0001). The same was true for two out of four subpopulations of young adults (female and white, ORs = 0.87&#x02013;0.89, p &#x0003c; 0.0001). For smoking cessation, none of the estimated ORs were statistically significant.</p></sec><sec id="S14"><title>3.3. Smoking intensity</title><p id="P24"><xref ref-type="table" rid="T3">Table 3</xref> shows the coefficients of the post-period indicator, estimated from the linear regression models for the number of days smoked during the past 30 days and the average number of cigarettes consumed per day of smoking, among current daily and nondaily smokers. Negative estimates indicate a reduction in the outcome following the April 1, 2009 tax increase.</p><p id="P25">Among the overall population of youth smokers, the average number of days smoked during the past month fell by 0.97 days (p = 0.0001) after the tax increase. Statistically significant reductions were also found for male, female and white youth. Among the overall population of young adults, the average number of days smoked during the past month fell by 0.84 days (p &#x0003c; 0.0001). The reductions were statistically significant for all subpopulations, ranging from 0.78 days for female young adults (p = 0.0002) to 0.95 for black young adults (p = 0.0164).</p><p id="P26">Youth daily smokers smoked on average 1.02 cigarettes per day less after the federal tax increase (p = 0.0011). Statistically significant reductions were also found for male, female and white youth daily smokers. In the overall population of youth nondaily smokers, 0.25 fewer cigarettes (p = 0.0114) were smoked per day after the tax increase. Similar results were found for female and white youth who were nondaily smokers.</p><p id="P27">Among young adult daily smokers, the average number of cigarettes smoked per day decreased by 0.92 (p &#x0003c; 0.0001) after the federal tax increase. Statistically significant reductions were also found for daily smokers in the male, female and white youth populations. Young adult nondaily smokers also smoked fewer cigarettes per day (&#x02212;0.45, p &#x0003c; 0.0001), with similar reductions for young adult nondaily smokers in the male, female and white subpopulations.</p></sec></sec><sec sec-type="discussion" id="S15"><title>4. Discussion</title><p id="P28">This study found that the April 1, 2009 federal cigarette excise tax increase of $0.62 per pack was associated with a decrease in smoking initiation among youth and decreases in past-month smoking, days smoked per month, and cigarettes per day among youths and young adults. There was no evidence that the tax increase was associated with a significant change in the likelihood of smoking cessation among youth and young adults.</p><p id="P29">Interestingly, the likelihood of smoking initiation among young adults did not change significantly after the tax increase. A possible explanation for this finding is that our measure of initiation not only captures regular smoking uptake but also occasional experimentation with cigarettes, which may be driven by peer effects and other noneconomic factors and therefore less sensitive to tax and price changes (<xref rid="R32" ref-type="bibr">Tyas &#x00026; Pederson, 1998</xref>). The null findings for smoking cessation may be related to the fact that the cessation indicator in the NSDUH requires the respondent to be smoke-free for an entire year. As such, it sets the bar for quitting quite high. Other studies have shown that short-term, more immediate cessation outcomes such as past 30-day cessation and the number of quit attempts are more sensitive to price and tax changes (<xref rid="R28" ref-type="bibr">Tauras, 2004</xref>; <xref rid="R31" ref-type="bibr">Tworek et al., 2010</xref>). Among current youth and young adult smokers, the number of days smoked during the past month declined after the tax increase, suggesting that some daily smokers may have become nondaily smokers. Also, fewer cigarettes were smoked per day after the tax increase, with the (absolute) reductions in the number of cigarettes being larger for daily smokers compared to nondaily smokers.</p><p id="P30">Another major finding of this study is that the strength of the association between the smoking outcomes and the April 1, 2009 federal tax increase varied by age, sex and race. In particular, among black youths, there were no significant associations between the tax increase and any smoking outcome. Among black young adults, the only statistically significant association was with days smoked per month. The likelihood of smoking initiation did not change significantly among black youth after the tax increase, whereas it did change for male, female and white youth. Smoking initiation decreased significantly among white young adults after the tax increase, but not among male, female or black young adults. Also, the odds of past-month cigarette use declined more among female and white youth and young adults, as opposed to the male and black subgroups. These findings are consistent with existing literature that has found that certain subpopulations are more responsive to tax changes than others (<xref rid="R34" ref-type="bibr">US DHHS, 2012b</xref>).</p><p id="P31">This study has two major strengths. First, it is the first to use multiple years of data from a large, nationally representative survey to specifically examine the impact of the April 1, 2009, federal tax increase on tobacco products on smoking among youth and young adults and a number of subpopulations (male, female, white, black). Second, we used a rich set of variables to control for differences in individual characteristics, changes in state tobacco control policies and changes in (proxies for) antismoking sentiment that coincided with the tax increase. Specifically, we controlled for demographic and socioeconomic characteristics, the increasing presence and restrictiveness of smoke-free laws, and the decreasing trend in smoking prevalence between 2002 and 2011.</p><p id="P32">A limitation of this study is that our models could not account for price movements that may have occurred before the tax increase. If, in anticipation of the federal tax increase, prices rose before April 1, 2009, smoking among youth and young adults could have started to decline before that date. This could, for example, explain our null finding for smoking initiation among young adults. Our estimates do not capture anticipatory effects and may, in fact, provide a lower bound for the full effect of the federal tax increase. A second limitation is that we were unable to use data on tobacco industry discounts and price reducing promotions (e.g., 2-for-1 deals, coupons), which have been shown to counter the depressing effect of price increases on smoking (<xref rid="R15" ref-type="bibr">Hyland et al., 2005</xref>; <xref rid="R20" ref-type="bibr">Pierce et al., 2005</xref>). A final limitation is because the NSDUH cessation variable is defined only for those who were daily smokers at some point in their lifetime, and because this applies to relatively few youth, sample sizes for the youth cessation analysis were relatively small.</p><p id="P33">This study has provided a detailed investigation of the relation between the April 1, 2009, federal tax increase on tobacco products and multiple smoking outcomes among youth and young adults. While for the overall populations of youth and young adults the tax increase was associated with reductions in the likelihood of past-month cigarette use, the number of days smoked and the number of cigarettes smoked per day, the reductions were not seen across all subgroups. Moreover, it appears that smoking initiation among young adults did not significantly change after the tax increase. The U.S. Healthy People 2020 objectives call for action to reduce tobacco use to the point where it is no longer a public health problem (<xref rid="R33" ref-type="bibr">US DHHS, 2012a</xref>). To achieve this goal, additional policy efforts are needed to substantially reduce tobacco initiation and use among youth and young adults. Such efforts will have to be informed by additional research. One topic for future study is an investigation into variables that moderate the impact of tax policy. While our study found differences across race and sex, it is also possible that other characteristics of tobacco control policy, such as smoke-free air laws in various settings, impacted the ability of the tax increase to change smoking behavior. Future research addressing such questions is critical, because it will support the development of effective, targeted tobacco control policies.</p></sec></body><back><fn-group><fn id="FN1"><p id="P34"><bold>Disclaimer</bold></p><p id="P35">The findings and conclusions of this study are those of the authors and do not necessarily reflect the views of the Substance Abuse and Mental Health Services Administration, the Centers for Diseases Control and Prevention, and the U.S. Department of Health and Human Services.</p></fn><fn id="FN2" fn-type="con"><p id="P36"><bold>Contributors</bold></p><p id="P37">MVH, MP, and BRL designed the study, conducted the data analysis, interpreted the results, and wrote the manuscript. JK, BH, RSC, and JCG interpreted the results and provided comments on manuscript drafts. All authors have approved the final manuscript.</p></fn><fn id="FN3" fn-type="conflict"><p id="P38"><bold>Conflict of interest statement</bold></p><p id="P39">None to declare.</p></fn></fn-group><ack id="S16"><title>Acknowledgments</title><p id="P40">We thank Lance Couzens, Vincent Keyes and Susan Murchie at RTI International, Jeremy Bray at the University of North Carolina at Greensboro, and Frank Chaloupka at the University of Illinois at Chicago for their assistance with various aspects of this study.</p><p id="P41"><bold>Role of funding sources</bold></p><p id="P42">This study was funded by a contract from the Substance Abuse and Mental Health Services Administration and the Centers for Disease Control and Prevention to RTI International. 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Non-U.S. Gov't]. <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1016/j.amepre.2006.02.001">http://dx.doi.org/10.1016/j.amepre.2006.02.001</ext-link>.</comment><pub-id pub-id-type="pmid">16704940</pub-id></element-citation></ref></ref-list></back><floats-group><table-wrap id="T1" position="float" orientation="landscape"><label>Table 1</label><caption><p id="P43">Rates of smoking initiation, past-month smoking, smoking cessation, and (for current smokers only) the average number of days smoked and the number of cigarettes per day, before and after the April 1, 2009 federal tax increase; 2002&#x02013;2011 NSDUH.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="1" colspan="1">Age</th><th align="left" rowspan="1" colspan="1">Outcome</th><th align="left" rowspan="1" colspan="1">Period</th><th align="left" rowspan="1" colspan="1">All</th><th align="left" rowspan="1" colspan="1">Male</th><th align="left" rowspan="1" colspan="1">Female</th><th align="left" rowspan="1" colspan="1">White</th><th align="left" rowspan="1" colspan="1">Black</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">12&#x02013;17</td><td align="left" rowspan="1" colspan="1">Initiation (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">6.7</td><td align="right" rowspan="1" colspan="1">6.2</td><td align="right" rowspan="1" colspan="1">7.2</td><td align="right" rowspan="1" colspan="1">7.5</td><td align="left" rowspan="1" colspan="1">4.4</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">5.1</td><td align="right" rowspan="1" colspan="1">5.0</td><td align="right" rowspan="1" colspan="1">5.3</td><td align="right" rowspan="1" colspan="1">5.5</td><td align="left" rowspan="1" colspan="1">3.5</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Past-month use (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">10.9</td><td align="right" rowspan="1" colspan="1">10.7</td><td align="right" rowspan="1" colspan="1">11.2</td><td align="right" rowspan="1" colspan="1">13.2</td><td align="left" rowspan="1" colspan="1">6.1</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">8.3</td><td align="right" rowspan="1" colspan="1">8.7</td><td align="right" rowspan="1" colspan="1">8.0</td><td align="right" rowspan="1" colspan="1">9.9</td><td align="left" rowspan="1" colspan="1">4.8</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Cessation (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">3.6</td><td align="right" rowspan="1" colspan="1">4.1</td><td align="right" rowspan="1" colspan="1">3.1</td><td align="right" rowspan="1" colspan="1">3.3</td><td align="left" rowspan="1" colspan="1">4.8</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">2.8</td><td align="right" rowspan="1" colspan="1">2.9</td><td align="right" rowspan="1" colspan="1">2.8</td><td align="right" rowspan="1" colspan="1">2.5</td><td align="left" rowspan="1" colspan="1">N/A</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Days smoked</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">14.6</td><td align="right" rowspan="1" colspan="1">14.9</td><td align="right" rowspan="1" colspan="1">14.3</td><td align="right" rowspan="1" colspan="1">15.7</td><td align="left" rowspan="1" colspan="1">11.6</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">13.4</td><td align="right" rowspan="1" colspan="1">13.3</td><td align="right" rowspan="1" colspan="1">13.5</td><td align="right" rowspan="1" colspan="1">14.6</td><td align="left" rowspan="1" colspan="1">N/A</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Cigarettes per day</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">4.8</td><td align="right" rowspan="1" colspan="1">5.1</td><td align="right" rowspan="1" colspan="1">4.4</td><td align="right" rowspan="1" colspan="1">5.3</td><td align="left" rowspan="1" colspan="1">3.0</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">3.9</td><td align="right" rowspan="1" colspan="1">4.0</td><td align="right" rowspan="1" colspan="1">3.9</td><td align="right" rowspan="1" colspan="1">4.5</td><td align="left" rowspan="1" colspan="1">N/A</td></tr><tr><td align="left" rowspan="1" colspan="1">18&#x02013; 25</td><td align="left" rowspan="1" colspan="1">Initiation (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">8.1</td><td align="right" rowspan="1" colspan="1">9.2</td><td align="right" rowspan="1" colspan="1">7.2</td><td align="right" rowspan="1" colspan="1">9.6</td><td align="left" rowspan="1" colspan="1">5.2</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">7.0</td><td align="right" rowspan="1" colspan="1">7.8</td><td align="right" rowspan="1" colspan="1">6.4</td><td align="right" rowspan="1" colspan="1">8.0</td><td align="left" rowspan="1" colspan="1">4.7</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Past-month use (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">38.5</td><td align="right" rowspan="1" colspan="1">42.5</td><td align="right" rowspan="1" colspan="1">34.5</td><td align="right" rowspan="1" colspan="1">43.9</td><td align="left" rowspan="1" colspan="1">27.7</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="left" rowspan="1" colspan="1">34.2</td><td align="right" rowspan="1" colspan="1">38.3</td><td align="right" rowspan="1" colspan="1">30.0</td><td align="right" rowspan="1" colspan="1">38.8</td><td align="left" rowspan="1" colspan="1">26.0</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Cessation (%)</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">3.6</td><td align="right" rowspan="1" colspan="1">3.0</td><td align="right" rowspan="1" colspan="1">4.3</td><td align="right" rowspan="1" colspan="1">3.6</td><td align="left" rowspan="1" colspan="1">3.2</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">3.8</td><td align="right" rowspan="1" colspan="1">3.7</td><td align="right" rowspan="1" colspan="1">4.0</td><td align="right" rowspan="1" colspan="1">3.4</td><td align="left" rowspan="1" colspan="1">4.4</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Days smoked</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">20.4</td><td align="right" rowspan="1" colspan="1">20.2</td><td align="right" rowspan="1" colspan="1">20.8</td><td align="right" rowspan="1" colspan="1">21.6</td><td align="left" rowspan="1" colspan="1">19.3</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">19.2</td><td align="right" rowspan="1" colspan="1">18.8</td><td align="right" rowspan="1" colspan="1">19.6</td><td align="right" rowspan="1" colspan="1">20.5</td><td align="left" rowspan="1" colspan="1">18.4</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">Cigarettes per day</td><td align="left" rowspan="1" colspan="1">Before</td><td align="right" rowspan="1" colspan="1">8.5</td><td align="right" rowspan="1" colspan="1">9.0</td><td align="right" rowspan="1" colspan="1">7.9</td><td align="right" rowspan="1" colspan="1">9.7</td><td align="left" rowspan="1" colspan="1">6.0</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">After</td><td align="right" rowspan="1" colspan="1">7.1</td><td align="right" rowspan="1" colspan="1">7.4</td><td align="right" rowspan="1" colspan="1">6.7</td><td align="right" rowspan="1" colspan="1">8.2</td><td align="left" rowspan="1" colspan="1">5.2</td></tr></tbody></table><table-wrap-foot><fn id="TFN1"><p id="P44">Notes: entries labeled &#x0201c;N/A&#x0201d; were suppressed because (unweighted) sample sizes were less than 500.</p></fn></table-wrap-foot></table-wrap><table-wrap id="T2" position="float" orientation="portrait"><label>Table 2</label><caption><p id="P45">Odds ratio estimates from the logistic regression models for smoking initiation, past-month cigarette use and cessation, comparing the odds of the outcome after and before the April 1, 2009 tax increase.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1">Age</th><th align="left" valign="top" rowspan="1" colspan="1">Population</th><th align="left" rowspan="1" colspan="1">Smoking initiation<break/>OR (p-value)</th><th align="left" rowspan="1" colspan="1">Past-month use<break/>OR (p-value)</th><th align="center" rowspan="1" colspan="1">Smoking cessation<break/>OR (p-value)</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">12&#x02013;17</td><td align="left" rowspan="1" colspan="1">All</td><td align="left" rowspan="1" colspan="1">0.83 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">0.83 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">0.84 (0.4684)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Male</td><td align="left" rowspan="1" colspan="1">0.87 (0.0140)</td><td align="left" rowspan="1" colspan="1">0.92 (0.0253)</td><td align="center" rowspan="1" colspan="1">0.87 (0.6849)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Female</td><td align="left" rowspan="1" colspan="1">0.79 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">0.75 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">0.86 (0.6355)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;White</td><td align="left" rowspan="1" colspan="1">0.79 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">0.80 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">0.90 (0.6857)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Black</td><td align="left" rowspan="1" colspan="1">0.88 (0.2364)</td><td align="left" rowspan="1" colspan="1">0.86 (0.0778)</td><td align="center" rowspan="1" colspan="1">N/A</td></tr><tr><td align="left" rowspan="1" colspan="1">18&#x02013;25</td><td align="left" rowspan="1" colspan="1">All</td><td align="left" rowspan="1" colspan="1">0.91 (0.0532)</td><td align="left" rowspan="1" colspan="1">0.92 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">1.00 (0.9949)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Male</td><td align="left" rowspan="1" colspan="1">0.92 (0.2143)</td><td align="left" rowspan="1" colspan="1">0.96 (0.0651)</td><td align="center" rowspan="1" colspan="1">1.12 (0.4198)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Female</td><td align="left" rowspan="1" colspan="1">0.91 (0.1601)</td><td align="left" rowspan="1" colspan="1">0.87 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">0.91 (0.4560)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;White</td><td align="left" rowspan="1" colspan="1">0.88 (0.0268)</td><td align="left" rowspan="1" colspan="1">0.89 (&#x0003c;0.0001)</td><td align="center" rowspan="1" colspan="1">0.85 (0.1670)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Black</td><td align="left" rowspan="1" colspan="1">0.92 (0.5253)</td><td align="left" rowspan="1" colspan="1">1.03 (0.6184)</td><td align="center" rowspan="1" colspan="1">1.41 (0.3216)</td></tr></tbody></table><table-wrap-foot><fn id="TFN2"><p id="P46">Notes: OR=odds ratio. The odds ratio is the odds of a given smoking outcome after April 1, 2009, divided by the odds before April 1, 2009. Two-sided p-values are given in parentheses.</p></fn><fn id="TFN3"><p id="P47">N/A: Due to the small sample size, the odds ratio could not be calculated.</p></fn></table-wrap-foot></table-wrap><table-wrap id="T3" position="float" orientation="portrait"><label>Table 3</label><caption><p id="P48">Linear regression estimates of the change in the average number of days smoked and the average number of cigarettes smoked per day (for current smokers), following the April 1, 2009 tax increase.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="3" valign="top" colspan="1">Age</th><th align="left" rowspan="3" valign="top" colspan="1">Population</th><th align="left" rowspan="3" valign="top" colspan="1">Days smoked during<break/>the past 30 days<break/>Coefficient (p-value)</th><th align="left" colspan="2" rowspan="1">Cigarettes per day of smoking</th></tr><tr><th align="center" colspan="2" valign="bottom" rowspan="1"><hr/></th></tr><tr><th align="left" valign="top" rowspan="1" colspan="1">Daily smokers<break/>Coefficient<break/>(p-value)</th><th align="left" valign="top" rowspan="1" colspan="1">Nondaily<break/>smokers<break/>Coefficient<break/>(p-value)</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">12&#x02013;17</td><td align="left" rowspan="1" colspan="1">All</td><td align="left" rowspan="1" colspan="1">&#x02212;0.97 (0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;1.02 (0.0011)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.25 (0.0114)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Male</td><td align="left" rowspan="1" colspan="1">&#x02212;0.83 (0.0109)</td><td align="left" rowspan="1" colspan="1">&#x02212;1.22 (0.0065)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.24 (0.1166)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Female</td><td align="left" rowspan="1" colspan="1">&#x02212;1.25 (0.0002)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.85 (0.0439)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.27 (0.0308)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;White</td><td align="left" rowspan="1" colspan="1">&#x02212;1.12 (0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.90 (0.0102)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.34 (0.0084)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Black</td><td align="left" rowspan="1" colspan="1">&#x02212;0.41 (0.5676)</td><td align="left" rowspan="1" colspan="1">&#x02212;2.43 (0.1266)</td><td align="left" rowspan="1" colspan="1">0.32 (0.2244)</td></tr><tr><td align="left" rowspan="1" colspan="1">18&#x02013;25</td><td align="left" rowspan="1" colspan="1">All</td><td align="left" rowspan="1" colspan="1">&#x02212;0.84 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.92 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.45 (&#x0003c;0.0001)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Male</td><td align="left" rowspan="1" colspan="1">&#x02212;0.88 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;1.04 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.51 (&#x0003c;0.0001)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Female</td><td align="left" rowspan="1" colspan="1">&#x02212;0.78 (0.0002)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.84 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.36 (0.0002)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;White</td><td align="left" rowspan="1" colspan="1">&#x02212;0.82 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;1.09 (&#x0003c;0.0001)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.57 (&#x0003c;0.0001)</td></tr><tr><td align="left" rowspan="1" colspan="1"/><td align="left" rowspan="1" colspan="1">&#x000a0;&#x000a0;Black</td><td align="left" rowspan="1" colspan="1">&#x02212;0.95 (0.0164)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.59 (0.1196)</td><td align="left" rowspan="1" colspan="1">&#x02212;0.29 (0.1796)</td></tr></tbody></table><table-wrap-foot><fn id="TFN4"><p id="P49">Notes: The coefficients indicate the amount by which smoking intensity (number of days smoked, cigarettes per day) changed after April 1, 2009. Two-sided p-values are given in parentheses.</p></fn></table-wrap-foot></table-wrap><boxed-text id="BX1" position="float" orientation="portrait"><caption><title>HIGHLIGHTS</title></caption><list list-type="bullet" id="L1"><list-item><p id="P50">The U.S. federal cigarette tax increased by $0.62 (159%) on April 1, 2009.</p></list-item><list-item><p id="P51">We model the impact of this increase on adult smoking outcomes.</p></list-item><list-item><p id="P52">We used state-level data from the 2002&#x02013;2011 National Survey on Drug Use and Health.</p></list-item><list-item><p id="P53">The tax increase reduced initiation and prevalence of youth and young adult smoking.</p></list-item><list-item><p id="P54">The impact varied by subpopulation.</p></list-item></list></boxed-text></floats-group></article>