Details:

Alternative Title:
Int J Infect Dis
Personal Author:
Haque, Farhana ; Husain, M. Mushtuq ; Ameen, Kazi Mohammad Hassan ; Rahima, Refat ; Hossain, M. Jahangir ; ... More +
Haque, Farhana ; Husain, M. Mushtuq ; Ameen, Kazi Mohammad Hassan ; Rahima, Refat ; Hossain, M. Jahangir ; Alamgir, A.S.M. ; Rahman, Mustafizur ; Rahman, Mahmudur ; Luby, Stephen P. Less -
Description:
Background

During July 2010, newspapers reported a respiratory disease outbreak in southwestern Bangladesh resulting in the admission of children to a secondary care hospital. We investigated this outbreak to determine the etiology and explore possible risk factors.

Methods

The hospital’s physician diagnosed children aged <2 years with cough, tachypnea or dyspnea, and expiratory wheeze as having acute bronchiolitis. We reviewed the hospital records and listed case patients admitted between 26 June and 26 July 2010. We surveyed the case patients and collected nasal and throat swabs to test for respiratory viruses.

Results

We identified 101 admitted acute bronchiolitis case patients. Fifty-nine (58%) of these were admitted between 16 and 20 July. Among the 29 case patients surveyed, the median age was 4 months and 65% were males. We identified respiratory syncytial virus (RSV) in 91% (21/23) of the samples, 43% of which had a dual viral infection. Most case patients (90%) were treated with broad-spectrum antibiotics. There were no reported deaths.

Conclusions

The sudden increase in admitted acute bronchiolitis case patients, their median age, and identification of RSV in the majority of samples suggest an outbreak of RSV bronchiolitis. Research to identify strategies to prevent respiratory infections including RSV in low-income settings should be prioritized. Factors that perpetuate antibiotic use in managing this viral syndrome should also be explored.


Subject:
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Acute Disease Anti-Bacterial Agents Article Child Child, Preschool Disease Outbreaks Female Hospitalization Humans Infant Male Respiratory Syncytial Viruses Respiratory Syncytial Virus Infections Risk Factors Socioeconomic Factors
Source:
Int J Infect Dis. 16(12):e866-e871.
Pubmed ID:
22938872
Pubmed Central ID:
PMC4629474
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
Singapore
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:feebe19c5ee6ed019d778d5dba89fec0d0a3678b42a8f317a14171f603b25f8c
Download URL:
https://stacks.cdc.gov/view/cdc/36364/cdc_36364_DS1.pdf
File Type:

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