Big racial/ethnic differences exist in menthol cigarette use. Very high proportions of black/African American adolescent smokers smoke menthol cigarettes [13,25-27]. Recent national data shows that about seven of ten African American smokers in this age group reported smoking menthol cigarettes, followed by about more than half of multi-race and Asian adolescent smokers (Figure 2). Data from the NSDUH survey shows that among adolescent smokers aged 12-17 years, 51.5% of Asians, 47.0% of Hispanics, and 41.4% of Native Hawaiians/Pacific Islanders reported smoking a menthol brand in the past 30 days. Similarly, a study conducted by Appleyard [13] and colleagues using 2000 NYTS data showed that 58.0% of Asians reported using a menthol cigarette brand. However, in another study conducted by Moolchan [19] in Baltimore, MD he found no difference in menthol cigarette use between blacks/African Americans (99.3% and 97.6% for males and females, respectively) and whites (92.3% and 87.5%, respectively). This study, however, used a convenience sample. Appleyard and colleagues also found that high school black/African American, Asian, and Native Hawaiian and Pacific Islander smokers were more likely to report smoking menthol cigarettes than their counterparts in middle school; while white and Hispanic high school smokers were less likely to report smoking menthol cigarettes than their counterparts in middle school [13]. A similar finding for whites and Hispanics (less smoking of menthol cigarettes among high school students) was found by Hersey and colleagues [14].

No consistent gender difference in menthol cigarette use is observed among adolescents. The scientific literature provided found no gender difference in menthol cigarette use between male and female adolescent smokers. Giovino [9], Hersey [14], Kaufman [15], Cummings [18], Johnston [21] found no gender difference between males and females who smoked the menthol brand Newport™*or reported smoking menthol cigarettes in general. The use of trade names is for informational purposes only and in no way implies endorsement by the US Government, the US Department of Health and Human Services, or the US Centers for Disease Control and Prevention. Additional analyses were performed using data from the NSDUH, NYTS, and MTFS. NSDUH data showed that girls aged 12-17 years were more likely to smoke menthol cigarettes than boys the same age in years 2004, 2005, and 2006, but no gender difference was observed in 2007 and 2008 (Table 1). When gender difference for this age group was assessed looking at the youth menthol leading cigarette brand Newport™, no differences were observed in any of these years (data not shown). Using NYTS data for years 2004, 2006, and 2009 combined, no gender difference in menthol cigarette use was observed in middle school (47.9% for females, 50.9% for males), however, a gender difference was observed in high school students, with females more likely to smoke menthol cigarettes than males (p-value= 0.0001) (Table 2). When data for all 3 years were combined, 49.2% of high school girls reported smoking menthol cigarettes compared to 41.0% of high school boys (results not shown). However, no differences were observed in using Newport™ between males and females when using 2004, 2006, and 2009 combined NYTS data (results not shown). MTFS for years 2004-2009 found no gender difference in smoking Newport™ among 8^th, 10^th, or 12^th graders (data not shown).

Research has shown that cigarette brand use varies by age, gender, and race/ethnicity [23,24,29,30]. Since efforts were initiated in specific studies in the late 1980’s [15,16] and the early 1990’s [18] to assess cigarette brand preference among adolescent smokers, Marlboro™, Newport™, and Camel™ were the top three cigarette brands smoked by adolescent smokers. Kaufman and colleagues [15] stated that even though market shares for the cigarette brands Marlboro™ and Camel ™changed little between 1989 and 1996, the prevalence of smoking Newport™ cigarettes doubled among white and Hispanic adolescents who usually bought their cigarettes during that period. Barker and colleagues [16] also found that the prevalence of smoking Newport™ cigarettes increased among adolescents from 1989 to 1993, and also for Camel™, while the prevalence of smoking Marlboro™ cigarettes decreased during this period. Consistent with results from earlier years, the 1999 MTFS report [21] showed that Marlboro™ was the predominant brand for 8^th, 10^th, and 12^th graders, ranging from 53.7%, 61.1%, to 65.2%; followed by the menthol brand Newport™ (22.5%, 17.7%, and 13.3%, respectively). The third-ranked brand was Camel™ (5.4%, 7.3%, and 9.6%, respectively). Also consistent with earlier studies [15,18] big racial/ethnic differences were found. While the great majority of white (61-70%) and Hispanic (57-65%) smokers smoked Marlboro™, the vast majority of blacks/African Americans smoked Newport™ (71-82%). Similar results were observed by Appleyard and colleagues [13] using 2000 NYTS data for middle and high school students. Appleyard found that the vast majority of white, Hispanic, Asian, and Native Hawaiian/Pacific Islander adolescent smokers smoked Marlboro™, and the vast majority of black/African American adolescent smokers smoked Newport™. The predominance of these three cigarette brands still persist [24]. Figures 3 to 5 using 1998 to 2008 MTFS surveys show that the three leading cigarette brands smoked by adolescents are Marlboro™, Newport™, and Camel™, in that order. A 2005 NSDUH report on cigarette brand preference showed that 81.3% of smokers aged 12-17 years and 82.4% of smokers aged 18 to 25 years smoked one of the top 3 brands [24]. Those 26 years or older reported to smoke a somewhat more diversified selection of cigarette brands, only 54.1% of smokers smoked one of the top 3 brands.

Data on use of menthol cigarettes by region they live in the U.S. is scarce. Compared to the East region of the United States, Kaufman and colleagues [15] found in the 1990’s that adolescents living in the Midwest, South, and West were less likely to smoke Newport™ and more likely to smoke Marlboro™.

It has been hypothesized that menthol cigarette brands play an important role in smoking initiation. When looking at three age groups (12-17 years, 18-25 years, 26 years or older), the younger the age group, the more likely it is to report smoking menthol cigarettes [10]. Unfortunately, data on this topic is scarce and data from cohort studies are lacking. It is important to clarify that the age of a smoker and smoking initiation is not equivalent. A person that is younger may have been smoking longer than an older person. For example, an adolescent aged 14 years may have been smoking for 3 years, while a young adult aged 19 years may have started smoking less than 1 year ago. Thus, age or age group (12-17 years, 18-25 years, 26 years or older) of the smoker is not equivalent to smoking initiation. The best study design to assess if adolescents and young adults are starting to smoke with a menthol cigarette brand is a prospective/cohort study. However, no cohort study we are aware of collects this type of information for persons younger than age 18 years, when most smoking initiation happens.

Due to lack of information on smoking initiation with menthol cigarettes from prospective studies, and in an attempt to determine if smoking initiation is correlated with menthol cigarette use, we conducted an analysis using cross-sectional data to determine the prevalence of self-reported menthol cigarette use at different “stages” or trajectories of cigarette smoking among adolescents in grades 6^th – 12.^th This type of analysis has been used to determine the prevalence of nicotine dependence at different stages/trajectories of cigarette smoking among adolescents [31]. Although this approach is inferior to collecting data from prospective studies, it is also true that patterns of cigarette smoking develop over months or years within individuals. In fact, most new smokers take an average of 2-3 years from the time they smoked their first cigarette to the time they become daily smokers [32]. Thus, the analysis presented here for respondents who started smoking less than 2 years ago may give us an insight on the relation of smoking initiation (earliest stages/trajectories of smoking) and the use of menthol cigarettes. We combined data from the 2004, 2006, and 2009 National Youth Tobacco Survey (NYTS). When looking at potential “stages” or trajectories of cigarette smoking and the use of menthol cigarettes, no significant differences were observed between “stages” or trajectories and the prevalence of smoking menthol cigarettes (Table 3). Among adolescents who smoked <1 cigarette per day (CPD) on 1-5 days of the past 30 days, 39.9 percent reported smoking menthol cigarettes. For those who smoked 1-5 CPD on 1-5 days, 6-9 days, 10-19 days, 20-29 days, and all 30 days, the self-reported prevalence of smoking menthol cigarettes among all smokers was 45.3%, 47.5%, 44.2%, 49.7%, and 46.6%, respectively. Among those smoking all 30 days, 42.7% of those who smoked 6-10 CPD, 43.3% of those who reported smoking 11-20 CPD, and 64.9% of those who smoked 20 or more CPD said they smoked a menthol brand. Thus, if smoking a menthol cigarette is a factor associated with smoking initiation, it would be expected to see a higher proportion of menthol cigarette smokers at the earlier stages/trajectories of cigarette smoking. In fact, we found the prevalence of menthol use to be lower among those who smoked <1 CPD on 1-5 days than those who smoked 1-5 CPD on 1-5 days or 1-5 CPD on 20-29 days and to be similar to those in other stages/trajectories of cigarette smoking. Also, those at the highest level of cigarette smoking (20+ CPD on all 30 days) were more likely to report smoking menthol cigarettes than all other smoking stages/trajectories. Thus, we found no indication that adolescent smokers are more likely to initiate smoking by smoking menthol cigarettes.

In general, the prevalence of cigarette smoking in the U.S. has been declining for adolescents over the past 10 years. The Youth Risk Behavior Survey (YRBS) shows that cigarette smoking among 9^th-12^th grade students fell by 44% from 1997 to 2007, from 36.4% to 20.0%, a percentage point decline in smoking prevalence of 16% [32], while the proportion of adolescent cigarette smokers reporting to smoke menthol cigarettes has increased significantly from 2004 to 2008 (Figure 6). Among all past-month smokers aged 12-17 years, the proportion of smokers reporting smoking menthol cigarettes increased significantly from 43.4% in 2004 to 48.3% in 2008, for an 11% increase over 4 years. This increase in the proportion of adolescent cigarette smokers who smoked menthol cigarettes reflects an increase in menthol cigarette use among white adolescents (40.3% to 46.0%), who were the only racial/ethnic group to show a significant increase over this period (results not shown). Looking at trends of some specific cigarette brands using MTFS data from 1998 to 2008, no consistent or significant change was observed during this period for Newport™, a predominantly menthol brand, among 8^th, 10^th, and 12^th graders, however, a significant increase was observed for Kool™, another menthol brand, for 10^th and 12^th graders (Figures 3, 4, 5). Similarly, using data from the 2004, 2006, and 2009 NYTS survey, a slight nonsignificant decrease in smoking Newport™ was observed among middle school smokers and no change among high school smokers (Figures 7 and 8). The lack of significant changes for specific cigarette brands over time may be due, at least in part, to less precision of the estimates due to smaller sample size numbers.

Camel™ and Marlboro™ cigarette brands come both in menthol and nonmenthol. The MTFS survey does not distinguish however between these two types of cigarettes. The MTFS data from 1998 to 2008 showed a significant increase in Camel™ use for boys and girls in 10^th and 12^th grade and declines in Marlboro™ use among smokers in 8^th, 10^th, and 12^th grade (Figures 3 to 5). A decline in Marlboro™ use was also observed among middle and high school boys and girls in the 2009 NYTS compared to previous years (data not shown). However, because most of the cigarette market share is driven by adult smokers, this decline may not be reflected in the overall Marlboro™ market share. Finally, Kreslake and colleagues reported that expenditures in advertising for nonmenthol brands declined from $309.3 million in 1998 to $39.8 million in 2005 while expenditures in advertising for menthol brands increased from $36.5 million to $43.8 million during that period [8]. It is known that adolescents are highly susceptible to advertising influences. Tobacco advertising, marketing, and promotion play an important role in increasing smoking initiation and tobacco use among youth [34]. Youth have been purposely targeted through advertising, marketing, and promotion [34]. The total weight of evidence presented by the 2008 NCI’s Monograph #19, which was assessed from multiple study types including experimental, cross-sectional, and longitudinal studies, and conducted by investigators from different disciplines using data from several countries, demonstrated a causal relationship between tobacco advertising, marketing, and promotion that ultimately increased smoking initiation and tobacco use [34]. It is possible that increases in expenditures in advertising for menthol brands resulted in increases in youth exposure to such advertising, which then resulted in increase prevalence of use of menthol cigarette brands.

Among adult smokers, the vast majority of black/African American adults reported smoking a menthol cigarette brand [18,22,35-39]. Other ethnic groups that may have a high proportion of menthol cigarette smokers are Puerto Ricans [37], Asians [39], and Native Hawaiians/Other Pacific Islanders (Figure 2). More recent information using data from the NSDUH survey shows that about eight of ten black/African American adult smokers reported smoking menthol cigarettes, followed by about half of Native Hawaiian and Other Pacific Island adult smokers (Figure 2). In fact, almost half of adult menthol cigarette smokers are from minority racial/ethnic groups. Analyses with this NHANES data confirm the NSDUH result that most black/African American smokers smoke a menthol brand (results not shown). Thus, one consistent finding is that black/African American smokers are far more likely to smoke a menthol cigarette brand than smokers of other U.S. racial/ethnic groups, however, some other racial/ethnic groups of smokers such as Hawaiians and Other Pacific Islanders and probably Puerto Ricans also smoke menthol cigarettes in high proportion [37,39].

Several studies [18,22,35-39] and further data analyses performed using recent NSDUH (2004-2008) and NHANES (2003-2008) data confirm that female adult smokers are more likely to smoke menthol cigarettes than male adult smokers (Table 4). The scientific literature is consistent in this finding for adult smokers but not for adolescent smokers. NSDUH (2004-2008) data shows that a higher proportion of adult female smokers than adult male smokers reported smoking menthol cigarettes. This was observed for both 18-25 years and 26 years or older. The gender difference was also observed among African Americans, whites, and Hispanics (Figure 9). The lack of a significant gender difference for the other racial/ethnic groups probably resulted from the lack of precision of the estimates for these populations due to small sample size. However, no gender difference was observed for the menthol brand Newport™ when using 2004-2008 NSDUH data (data not shown). Further analysis using NHANES 2003-2008 data in which smokers showed their pack of cigarettes to the interviewer also showed a gender difference where female adult smokers aged 26 years or older were more likely to smoke a menthol brand than their male counterpart, but not so among the age group 20-25 years old, probably due to smaller sample size number of smokers in the survey in this age group (results not shown). No gender difference in Newport™ use was observed between males and females in the age groups 20-25 years or 26 years or older in NHANES (results not shown).

We mentioned earlier that cigarette brand use varies by age and that cigarette brands selection is more diversified for adults aged 26 years or older than those aged 12-17 years and 18-25 years old. The 2005 NSDUH report showed that 54.1% of smokers’ aged 26 years or older smoked one of the top 3 brands (Marlboro™, Newport™, Camel™) compared to 81.3% of smokers aged 12-17 years and 82.4% of smokers aged 18 to 25 years (24). Table 5 and Figure 10 show the distribution of specific menthol and nonmenthol brand use by smokers aged 20 years or older verified by the UPC code. The percent of menthol smokers among all smokers for 2003-2008 was 27.4%. This is similar to reported market share data for years 2003-2005 [1], where menthol brands represented about 26% to 27% of the market share of cigarettes; except for 2006, when it was reported to be 20%. Both Table 5 and Figure show that among specific menthol brands, Newport™ is the leading menthol brand smoked by adult smokers (7.8% - 11.6%), followed by Marlboro Menthol™ (3.9% - 5.9%), Kool ™ (2.4% - 3.2%), and Salem™ (1.2% - 3.2%). When menthol brands other than the ones mentioned above were combined, they represented about 7.0% - 8.7% of the brands smoked by all adult smokers. Marlboro™ nonmenthol brands (33.3% - 39.8%) and nonmenthol brands (27.2% - 33.0%) other than Camel™ represented the vast majority of brands smoked by adult smokers.

Data on use of menthol cigarettes by region they live in the U.S. is also scarce for adults. A table using 2000 NSDUH data showed that smokers living in the Northeast of the United States were more likely to report smoking menthol cigarettes [9] than those living in the South, North Central, and West of the United States. Similarly, a 2005 NSDUH report on brand preferences confirmed that 18.2% of smokers aged 12 years or older, the vast majority of them adult smokers, and living in the Northeast reported smoking Newport™ compared to 10.7%, 12.4%, and 3.3% in the Midwest, South, and West of the United States, respectively [24].

Data on income and the use of menthol cigarettes is almost nonexistent in the scientific literature. A data analysis using 2004-2008 NSDUH showed that adult smokers with family incomes of less than $50,000 were more likely to smoke menthol cigarettes than adult smokers with higher family incomes (Figure 11).

From 2004 to 2008, the proportion of menthol cigarette smokers among all cigarette smokers increased among adults aged 18-25 years and 26 years or older (Figure 6). The proportion of cigarette smokers who reported smoking menthol cigarettes increased significantly from 2004 to 2008 among white and Hispanic men (Figure 12). No changes were observed for white, black/African American, and Hispanic women (results not shown). The lack of significant changes for black African American men and women may be explained, at least in part, to a ceiling effect, where about 80% of men and 90% of women who smoked already smoked a menthol brand. Looking at trends in cigarette brand use from 2002 to 2008 using NSDUH data, no significant changes of Marlboro™, Newport™, or Camel™ use were observed for young adults aged 18-25 years (Figure 13), nor for smokers aged 26 years or older (Figure 14). The lack of significant changes for specific cigarette brands over time may be due, at least in part, to less precision of the estimates due to smaller sample size numbers. Kreslake and colleagues reported an increase for Marlboro Menthol™ sales data [8]. They found that although cigarette sales in the U.S. declined 22% from 2000 to 2005, that the sales of menthol cigarettes remained stable and that Marlboro Menthol™ had a consistent market share growth that started in the early 1990’s up to 2006, most recent data available when they published their article. In 2006, the authors reported, Newport™ was the leading menthol brand, followed by Marlboro Menthol™, which they stated was particularly popular among young adult smokers. Using 2004-2008 NSDUH data, we found that for adult smokers, even though the prevalence of cigarette smoking remained the same in 2008 (20.6%) compared to 2004 (20.9%), the self-reported use of menthol cigarettes increased during those years for adults, more so for those aged 18-25 years than those aged 26 years or older.

As previously stated, self-reports of types of cigarettes smoked are subject to bias. For example, Hersey [14], Giovino and colleagues [9] as well as Kreslake and colleagues [8] found that menthol cigarette use self-reports are subject to misclassification, probably more so on certain subgroups such as adolescents. Kreslake and colleagues found that 83% of adolescents aged 12-17 years who smoked Newport™, a menthol brand, also reported they were smokers of menthol cigarettes when asked in a separate question, thus 17% of them reported to be smokers of nonmenthol cigarettes which is inconsistent with the menthol brand Newport. When a similar assessment was made for participants aged 35 years or older, they found that only 5% of Newport™ smokers reported in a separate question to be smokers of a nonmenthol brand [8].

Compared to most adult smokers, most adolescent smokers can be considered to be novice smokers. The fact that a substantial proportion of current (smoking at least 1 day of past 30 days, even a puff) adolescent smokers (e.g., first triers, experimenters, <weekly smokers) will not be considered to be an established adult smoker (100 cigarettes smoked or more in lifetime) is likely related to the differential misreporting of the use of menthol cigarettes between the two age groups. For example, a paper published recently by Caraballo and colleagues [31] shows that 26.8% of current adolescent smokers aged 12-18 years started smoking <1 year prior to the time of the interview. In contrast, the vast majority of adult smokers are established smokers, smoke every day (80%), buy their own cigarettes, and most of them smoke at least half-a-pack a day. Learning specific brand characteristics (e.g., full flavor, light or ultra-light; Marlboro Mild™, Marlboro Menthol™, Newport; ™ menthol or nonmenthol) develops over time. It is likely that many adolescent smokers are less knowledgeable than adult smokers of the specific characteristics of the cigarettes they smoke, especially those who are early in the stage/trajectory of cigarette smoking or those who do not (usually) buy their cigarettes. Thus, adolescent smokers are probably more prone to misreport the type of cigarettes they smoke, including a menthol brand, than adult smokers do.

As previously mentioned, collecting information on the type of cigarettes smoked using the 8 or 12 digit UPC bar code information on the side of the cigarette pack may be seen as a solution to the problem of obtaining accurate information on whether the brand smoked by an adolescent is menthol or non-menthol. However, most of the national youth surveys (MTFS, NYTS, YRBS) that collect this type of information are conducted in a school-setting, a place where adolescents who smoke may not bring their cigarettes and where most schools will not allow it. In household surveys (e.g., NSDUH), some of the novice or even experienced smokers may not want their parents/caregivers to know they smoke. Also, they may be less likely than an adult smoker to have a pack of cigarettes with them. There is ample evidence that a degree of self-report bias exists in reporting the use of mentholated cigarettes, especially among adolescents. Assuming that this type of bias is fairly constant over time, the increase over time in menthol cigarette use among adolescents and adults is a real one.