Infect Dis Obstet GynecolinfectdisobgynInfectious Diseases in Obstetrics and Gynecology1064-74491098-0997Hindawi Publishing Corporation157639111784599UWK71FLU6UQ3MJFE10.1080/10647440400020711Research ArticleVaginal flora morphotypic profiles and assessment of bacterial vaginosis in women at risk for HIV infection.TohillBeth C.btohill@cdc.govHeiligCharles M.KleinRobert S.RompaloAnneCu-UvinSusanBrownWilliamDuerrAnnCenters for Disease Control and Prevention, National Center for Chronic Disease and Public Health Prevention, Division of Nutrition and Physical Activity, Atlanta, GA 30341, USA.Sep-Dec2004123-4121126

Specific morphotypic profiles of normal and abnormal vaginal flora, including bacterial vaginosis (BV), were characterized. A prospective study of 350 women yielded concurrent Gram-stain data and clinical assessment (n = 3455 visits). Microbiological profiles were constructed by Gram stain. Eight profile definitions were based on dichotomizing the levels of Lactobacillus, Gardnerella, and curved, Gram-negative bacillus (Mobiluncus) morphotypes. Of these, two were rare, and the other six demonstrated a graded association with the clinical components of BV. The proposed profiles from the Gram stain reflect the morphotypic categories describing vaginal flora that may enable clearer elucidation of gynecologic and obstetric outcomes in various populations.