Details:

Alternative Title:
Open Forum Infect Dis
Personal Author:
Grant, Robert M. ; Smith, Dawn K.
Grant, Robert M. ; Smith, Dawn K. Less -
Description:
Best practices for integrating human immunodeficiency virus (HIV) testing and antiretroviral interventions for prevention and treatment are suggested based on research evidence and existing normative guidance. The goal is to provide high-impact prevention services during periods of substantial risk. Antiretroviral medications are recommended for postexposure prophylaxis (PEP), pre-exposure prophylaxis (PrEP), and treatment of HIV infection. We reviewed research evidence and current normative guidelines to identify best practices for integrating these high-impact prevention strategies. More sensitive HIV tests used for screening enable earlier diagnosis and treatment of HIV infection, more appropriate counseling, and help limit drug resistance. A fully suppressive PEP regimen should be initiated based on exposure history or physical findings when sensitive diagnostic testing is delayed or not available and antibody tests are negative. Transitions from PEP to PrEP are often warranted because HIV exposure events may continue to occur. This algorithmic approach to integrating PEP, PrEP, and early treatment decisions may increase the uptake of these interventions by a greater number and diversity of knowledgeable healthcare providers.
Subjects:
[+]
Anti-Retroviral Agents Female HIV Infections Prevention & Control Humans Male Post-Exposure Prophylaxis Pre-Exposure Prophylaxis
Source:
Open Forum Infect Dis. 2015; 2(4).
Pubmed ID:
26512356
Pubmed Central ID:
PMC4621406
Document Type:
Journal Article
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:4bb4dc52811992fa045fda9e3750e29382543882fe089d9e3829f99d4c080071
Download URL:
https://stacks.cdc.gov/view/cdc/35509/cdc_35509_DS1.pdf
File Type:

Supporting Files

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