Emerg Infect DiseidEmerging Infectious Diseases1080-60401080-6059Centers for Disease Control115855402631764Research ArticleExposure of domestic mammals to West Nile virus during an outbreak of human encephalitis, New York City, 1999.KomarN.nck6@cdc.govPanellaN. A.BoyceE.Centers for Disease Control and Prevention, P.O. Box 2087, Fort Collins, CO 80522, USA.Jul-Aug200174736738

We evaluated West Nile (WN) virus seroprevalence in healthy horses, dogs, and cats in New York City after an outbreak of human WN virus encephalitis in 1999. Two (3%) of 73 horses, 10 (5%) of 189 dogs, and none of 12 cats tested positive for WN virus-neutralizing antibodies. Domestic mammals should be evaluated as sentinels for local WN virus activity and predictors of the infection in humans.