Emerg Infect DiseidEmerging Infectious Diseases1080-60401080-6059Centers for Disease Control112663072631691Research ArticlePathologic studies of fatal cases in outbreak of hand, foot, and mouth disease, Taiwan.ShiehW. J.wshieh@cdc.govJungS. M.HsuehC.KuoT. T.MountsA.ParasharU.YangC. F.GuarnerJ.KsiazekT. G.DawsonJ.GoldsmithC.ChangG. J.ObersteS. M.PallanschM. A.AndersonL. J.ZakiS. R.Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop G32, Atlanta, GA 30333, USA.Jan-Feb200171146148

In 1998, an outbreak of enterovirus 71-associated hand, foot, and mouth disease occurred in Taiwan. Pathologic studies of two fatal cases with similar clinical features revealed two different causative agents, emphasizing the need for postmortem examinations and modern pathologic techniques in an outbreak investigation.