Details:

Alternative Title:
Int J Obes (Lond)
Personal Author:
Hinkle, SN ; Sharma, AJ ; Kim, SY ; Schieve, LA
Hinkle, SN ; Sharma, AJ ; Kim, SY ; Schieve, LA Less -
Description:
OBJECTIVE

Obesity is prevalent among women of reproductive age, and developmental disabilities in children continue to increase. We examined associations between mother's prepregnancy body mass index (BMI) and physical and developmental disabilities, and objective measures of reading and math skills and fine and gross motor function in children.

METHODS

We used the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B; n = 5200), a cohort of children born in 2001 and followed until kindergarten. Children were classified according to maternal prepregnancy BMI (in kg per m2): underweight (BMI <18.5), normal weight (BMI 18.5–24.9), overweight (BMI 25.0–29.9), obese class I (BMI 30.0–34.9) and obese class II/III (BMI ≥35.0). Parent reports of doctor-diagnosed disabilities were collected up to kindergarten and classified as learning and behavioral or physical. Children's reading and math and fine and gross motor function were assessed at kindergarten according to standardized tests. Linear and modified logistic regression models were adjusted for maternal sociodemographic variables, family enrichment variables, and children's sex, age and year of kindergarten entry. Additional adjustment for current child BMI was performed in separate models. All data are weighted to be nationally representative of the children born in 2001.

RESULTS

Compared with children of normal-weight mothers, children born to obese class II/III mothers had an increased risk of learning or behavioral (risk ratio 1.67; 95% confidence interval 1.27, 2.21)), but not physical disabilities (risk ratio 0.57; 95% confidence interval 0.27, 1.22). Gross (P<0.001), but not fine (P = 0.06) motor function was significantly associated with maternal BMI, but gross motor function was attenuated after adjustment for current child BMI (P = 0.05). Children's reading scores (P = 0.01) but not math scores (P = 0.11) were significantly associated with maternal BMI.

CONCLUSIONS

In this nationally representative US cohort, children born to severely obese mothers had an increased risk for diagnosed learning and behavioral but not physical disabilities by kindergarten.


Subjects:
[+]
Adult Body Mass Index Child, Preschool Child Behavior Disorders Child Development Developmental Disabilities Female Follow-Up Studies Humans Learning Disorders Longitudinal Studies Male Mothers Obesity Odds Ratio Pregnancy Pregnancy Complications Risk Factors Thinness Time Factors
Source:
Int J Obes (Lond). 2013; 37(10):1344-1351
Pubmed ID:
23860335
Pubmed Central ID:
PMC4407562
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:7670e611b29ca092d252ab60e33bf05d8e0b974896085c2ef104a11ac7f495ab
Download URL:
https://stacks.cdc.gov/view/cdc/30640/cdc_30640_DS1.pdf
File Type:

Supporting Files

• 	nihms-676604-f0001.gif	gif
  	nihms-676604-f0001.jpg	jpeg
  	nihms-676604.nxml	xml
  	NIHMS676604-supplement-Supplemental.pdf	pdf

More +