Examination of Sex Differences in a Large Sample of Young Children with Autism Spectrum Disorder and Typical Development

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  Reinhardt, Vanessa P. ; Wetherby, Amy M. ; Schatschneider, Christopher
• Description:
  Despite consistent and substantive research documenting a large male to female ratio in Autism Spectrum Disorder (ASD), only a modest body of research exists examining sex differences in characteristics. This study examined sex differences in developmental functioning and early social communication in children with ASD as compared to children with typical development. Sex differences in adaptive behavior and autism symptoms were also examined in children with ASD. Participants (n = 511) were recruited from the Florida State University FIRST WORDS® Project and University of Michigan Autism and Communication Disorders Center. Analyses did not reveal significant effects of sex or a diagnostic group by sex interaction, suggesting a similar phenotype in males and females early in development. Further research is needed to examine sex differences across development.
• Subjects:
  Adaptation, Psychological Case-Control Studies Child, Preschool Child Development Child Development Disorders, Pervasive Communication Female Florida Humans Male Michigan Phenotype Sex Characteristics

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• Source:
  J Autism Dev Disord. 45(3):697-706
• Pubmed ID:
  25189824
• Pubmed Central ID:
  PMC4342305
• Document Type:
  Journal Article
• Funding:
  R01 HD065272/HD/NICHD NIH HHSUnited States/ ; R01HD065272/HD/NICHD NIH HHSUnited States/ ; UA3 MC 11055/PHS HHSUnited States/ ; U01DD000304/DD/NCBDD CDC HHSUnited States/ ; R01DC007462/DC/NIDCD NIH HHSUnited States/ ; U01 DD000304/DD/NCBDD CDC HHSUnited States/ ; R01 DC007462/DC/NIDCD NIH HHSUnited States/
• Volume:
  45
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:083f07ba82783dbe8cf303a5a05246ad45d95c2a0a646cd485dcc5e375a605cb
• Download URL:
  https://stacks.cdc.gov/view/cdc/30307/cdc_30307_DS1.pdf
• File Type:
  [PDF - 275.07 KB ]