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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.3" xml:lang="en" article-type="research-article"><?properties manuscript?><processing-meta base-tagset="archiving" mathml-version="3.0" table-model="xhtml" tagset-family="jats"><restricted-by>pmc</restricted-by></processing-meta><front><journal-meta><journal-id journal-id-type="nlm-journal-id">9918750589006676</journal-id><journal-id journal-id-type="pubmed-jr-id">53093</journal-id><journal-id journal-id-type="nlm-ta">Subst Use Addctn J</journal-id><journal-id journal-id-type="iso-abbrev">Subst Use Addctn J</journal-id><journal-title-group><journal-title>Substance use &#x00026; addiction journal</journal-title></journal-title-group><issn pub-type="ppub">2976-7342</issn><issn pub-type="epub">2976-7350</issn></journal-meta><article-meta><article-id pub-id-type="pmid">39138912</article-id><article-id pub-id-type="pmc">11823082</article-id><article-id pub-id-type="doi">10.1177/29767342241267074</article-id><article-id pub-id-type="manuscript">HHSPA2025665</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Cross-site evaluation of alcohol screening and brief intervention
implementation programs in healthcare systems serving individuals of
reproductive age</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Vendetti</surname><given-names>Janice</given-names></name><degrees>MPH</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Bangham</surname><given-names>Candice</given-names></name><degrees>MPH</degrees><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Riba</surname><given-names>Melissa</given-names></name><degrees>MA</degrees><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>Whitmore</surname><given-names>Corrie</given-names></name><degrees>PhD</degrees><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Gallucci</surname><given-names>Karen Steinberg</given-names></name><degrees>PhD</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Hanson</surname><given-names>Bridget L.</given-names></name><degrees>PhD</degrees><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0003-2044-9270</contrib-id><name><surname>Greece</surname><given-names>Jacey A.</given-names></name><degrees>DSc, MPH</degrees><xref rid="A2" ref-type="aff">2</xref></contrib></contrib-group><aff id="A1"><label>1</label>University of Connecticut School of Medicine, Farmington,
CT</aff><aff id="A2"><label>2</label>Boston University School of Public Health, Boston, MA</aff><aff id="A3"><label>3</label>Center for Health and Research Transformation, University
of Michigan, Ann Arbor, MI</aff><aff id="A4"><label>4</label>Center for Behavioral Health Research and Services,
University of Alaska Anchorage, Anchorage, AK</aff><author-notes><corresp id="CR1"><bold>Corresponding Author:</bold> Jacey A. Greece, DSc, MPH,
Clinical Associate Professor, Department of Community Health Sciences, Boston
University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118,
<email>jabloom@bu.edu</email></corresp><fn fn-type="con" id="FN1"><p id="P1"><bold><italic toggle="yes">Author Contributions.</italic></bold> JV and JAG
prepared the manuscript. All authors contributed to the conceptualization,
methodology and review of the manuscript. JV, CB, CW, JAG extracted the
data. JV, CB, MR, CW, JAG conducted the statistical analysis. JV, CB, MR,
KS, JAG contributed to the writing and CW, BLH edited the manuscript, with
final edits conducted by JV, MR, JAG.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>30</day><month>10</month><year>2024</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>8</month><year>2024</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>4</month><year>2025</year></pub-date><volume>46</volume><issue>2</issue><fpage>461</fpage><lpage>475</lpage><abstract id="ABS1"><sec id="S1"><title>Background.</title><p id="P2">With U.S. Centers for Disease Control and Prevention funding, from
2018&#x02013;2022, four large healthcare systems (n=53 health centers across
seven states) serving people of reproductive age trained staff and provided
implementation support for alcohol screening and brief intervention (SBI).
This cross-site evaluation explores each healthcare system&#x02019;s
implementation approach to implement SBI, reduce excessive alcohol use, and
prevent prenatal alcohol exposure (PAE) and fetal alcohol spectrum
disorders.</p></sec><sec id="S2"><title>Methods.</title><p id="P3">The SBIRT (Screening, Brief Intervention, and Referral to Treatment)
Program Matrix framed the multi-level strategies to implement alcohol SBI
programs from 2018&#x02013;2022. Qualitative and quantitative data sources
examined outcomes, guided by one logic model, through systems-level process
data and provider-level performance metrics. Data analyses utilized
frequencies and means for quantitative data and themes for qualitative data
according to an established framework.</p></sec><sec id="S3"><title>Results.</title><p id="P4">Successful approaches within systems included using electronic health
records, flexible implementation and workflow protocols, customized training
and technical assistance programs, quality assurance feedback loops, and
stakeholder buy-in. Centralized management structures were efficient in
standardizing implementation across health centers. Decentralized management
structures used tailored approaches, enhancing provider/staff SBI
acceptance. Across systems, 1,259 staff (e.g., clinicians, medical
assistants) were trained to provide alcohol SBI services and reported
pre-post training increases in self-efficacy in performing brief
intervention; skills in PAE counseling; and confidence in screening.
Fifty-three (48 providing data) health centers implemented alcohol SBI,
screening 106,826 patients over the study period with most of the 10,087
patients who screened positive for excessive alcohol use receiving a BI.</p></sec><sec id="S4"><title>Conclusions:</title><p id="P5">Maximizing the use of technology, employing flexibility in program
delivery, and institutionalizing processes and protocols improved workflow,
efficiency, and program reach. Ongoing partnership and stakeholder
communication identify areas for ongoing improvement, engagement, and best
practices for sustainability around substance use screening, which are
essential with increases in substance use since the pandemic.</p></sec></abstract><kwd-group><kwd>Cross-site evaluation</kwd><kwd>alcohol screening and brief intervention</kwd><kwd>substance use screening and brief intervention</kwd><kwd>SBIRT Program Matrix</kwd><kwd>screening</kwd><kwd>brief intervention and referral to treatment</kwd><kwd>SBI</kwd><kwd>SBIRT</kwd><kwd>FASD</kwd><kwd>fetal alcohol spectrum disorders</kwd></kwd-group></article-meta></front><body><sec disp-level="2" id="S6"><title>Background</title><p id="P6">Alcohol use among women continues to increase,<sup><xref rid="R1" ref-type="bibr">1</xref></sup> and those who may become pregnant are at
additional risk for alcohol-exposed pregnancies (AEPs) resulting in miscarriage,
stillbirth, and a range of lifelong physical, behavioral, and intellectual
disabilities known as fetal alcohol spectrum disorders (FASDs).<sup><xref rid="R2" ref-type="bibr">2</xref></sup> It is estimated that up to 1 in
20 U.S. school-aged children might have an FASD.<sup><xref rid="R3" ref-type="bibr">3</xref></sup> Four healthcare systems implemented and
systematically evaluated alcohol screening and brief intervention (SBI) in
primary and reproductive care settings that provided health services for females
and women of reproductive age. Funded by the Centers for Disease Control and
Prevention (CDC) with cooperative agreements between the healthcare systems and
academic institutions, the four-year implementation projects began in
2018.<sup><xref rid="R4" ref-type="bibr">4</xref></sup> While SBI has
been established as effective in reducing drinking and associated
harm,<sup><xref rid="R5" ref-type="bibr">5</xref>&#x02013;<xref rid="R8" ref-type="bibr">8</xref></sup> including the risk of AEP,<sup><xref rid="R9" ref-type="bibr">9</xref></sup> alcohol SBI has not been widely
implemented and even fewer healthcare settings have evaluated systems-level
strategies to support implementation.<sup><xref rid="R10" ref-type="bibr">10</xref></sup></p><p id="P7">Despite strategies and guidelines for delivering alcohol SBI, adoption in
practice can be challenging. Accordingly, variations in operationalizing alcohol
SBI within settings results in numerous implementation and evaluation
frameworks.<sup><xref rid="R11" ref-type="bibr">11</xref>&#x02013;<xref rid="R13" ref-type="bibr">13</xref></sup> One framework, the Screening,
Brief Intervention and Referral to Treatment (SBIRT) Program Matrix was designed
to understand how program variations are associated with alcohol SBI-specific
implementation success.<sup><xref rid="R10" ref-type="bibr">10</xref></sup></p><p id="P8">A previous cross-site evaluation found implementation challenges can be
addressed by adequate start-up and planning periods, comprehensive education and
training, development of intra-and inter-organizational communication, and
emphasis on collaboration for buy-in from practitioners and opinion
leaders.<sup><xref rid="R14" ref-type="bibr">14</xref></sup>
Additionally, a recent scoping review on SBIRT program implementation
research<sup><xref rid="R15" ref-type="bibr">15</xref></sup> found that
most studies identified efforts to involve stakeholders rather than engage
consumers of healthcare in efforts to promote implementation, and that the
strongest implementation efforts were on impacts on screening levels instead of
brief intervention rates.</p><p id="P9">There are limited evaluations on cross-site approaches to screening,
brief intervention, and referral to treatment. While keeping resources and
activities constant, this rigorous evaluation provides important opportunities
for context-specific recommendations for implementation. This is timely given
the pandemic-related increases in alcohol consumption and alcohol-related
deaths<sup><xref rid="R16" ref-type="bibr">16</xref></sup> and the need
for enhanced screening and prevention efforts.</p><p id="P10">This paper focuses on gaps in current research and implementation of
alcohol SBI during the COVID-19 pandemic, which necessitated significant shifts
in SBI training formats (in-person to virtual), program delivery (telehealth),
and data collection strategies (virtual assessments and online observations). We
describe the cross-site evaluation of alcohol SBI implementation across four
healthcare systems within the framework of the SBIRT Program Matrix to guide
future considerations for application, particularly in the pandemic context.</p></sec><sec id="S7"><title>Methods</title><sec id="S8"><title>Aim.</title><p id="P11">This mixed methods cross-site evaluation aimed to describe
implementation of alcohol SBI programs in different healthcare settings, the
impact of those activities on systems-level and provider-level outcomes, and
inform best-practice recommendations.</p></sec><sec id="S9"><title>Sample.</title><p id="P12">The four academic-healthcare system partnerships provided women&#x02019;s
health care through Planned Parenthood regional affiliates (University of Alaska
Anchorage Center for Behavioral Health Research Services with Planned Parenthood
Great Northwest, Hawai&#x02019;i, Alaska, Indiana, Kentucky [PPGNHAIK] and
University of Connecticut, School of Medicine with Planned Parenthood of
Southern New England [PPSNE]) and through large medical systems (Boston
University School of Public Health with Boston HealthNet, Boston Medical Center
[BMC] and Center for Health and Research Transformation and Henry Ford Health
[HFH]).</p></sec><sec id="S10"><title>Cross-Site Evaluation Design.</title><p id="P13">The CDC Logic Model for Implementing Alcohol Screening and Brief
Intervention Programs in Primary Healthcare Settings (<xref rid="F1" ref-type="fig">Figure 1</xref>) guided each healthcare system&#x02019;s
implementation efforts while allowing flexibility in approach to accomplish the
required outcomes. The logic model specified the overarching performance
measures and provided common metrics for assessing outcomes.</p><p id="P14">The SBIRT Program Matrix provided a template to identify, classify, and
organize commonalities and variations in implementation factors within and
across programs, as well as specifying systems-level and provider-level
outcomes.<sup><xref rid="R10" ref-type="bibr">10</xref></sup> Long-term
patient outcomes were not evaluated. Emphasis was on examining implementation
factors across programs to understand factors that fostered success of
intermediate outcomes, which serve as proxies for longer-term goals, including
patient outcomes such as reduction in excessive alcohol use and prevention of
AEPs and FASDs.</p></sec><sec id="S11"><title>Data Sources and Analysis.</title><p id="P15">Quantitative and qualitative data sources were used to examine systems-
and provider-level outcomes in a way that reduced burden on respondents, aligned
with current systems and protocols, and utilized existing data and evaluation
infrastructure (<xref rid="T1" ref-type="table">Table 1</xref>, <xref rid="SD1" ref-type="supplementary-material">Online Supplemental Material 1</xref>).
Because data collection used existing, site-specific evaluation methods, there
was variation in outcome data provided across sites. Human subjects review and
exemption or approval were obtained from each academic institution and/or
healthcare system.</p><sec id="S12"><title>Systems-Level Implementation Data Sources.</title><p id="P16">Programs obtained site-specific workflow documentation for
screening, brief intervention and referral procedures (e.g., when each
service is conducted and by whom) using observation data and meeting notes
to record SBI implementation processes; training attendance records to
quantify number and roles of individuals trained; and de-identified
electronic health record (EHR) data to measure documentation of SBI service
delivery. Descriptive quantitative analyses were conducted using
administrative and EHR data, provider surveys, and administrative reports to
describe the population and outcomes.</p><p id="P17">Programs also provided supplemental data including: secondary data
to contextualize findings across sites (n=2); environmental scans to
describe SBI protocols prior to implementation (n=2); key informant
interviews and focus groups of leadership and staff to contextualize data,
describe SBI workflows and processes, and identify supports to promote
efforts (n=3); site visits to document program fidelity (n=1); training
observations to track process measures, provide quality improvement
recommendations, and measure program fidelity (n=1); and, podcast metrics
and Continuing Medical Education (CME) data to measure knowledge after
listening to a project-developed podcast.</p></sec><sec id="S13"><title>Provider-Level Data.</title><p id="P18">Provider-level data were collected via anonymous online staff
surveys before and after SBI training (PPGNHAIK, PPSNE, BMC). Questions
included skills, attitudes, and self-efficacy about SBI activities; training
satisfaction; readiness to change practice behavior; facilitators and
barriers to integration of SBI protocols and workflows; and FASD knowledge.
Each site utilized questions tailored from validated SBIRT-focused surveys
and/or developed custom items to correspond to the site activities. For
example, PPSNE used questions derived from the Cutting Back SBI
Program.<sup><xref rid="R17" ref-type="bibr">17</xref></sup> A
sample of questions for each site and topic area (including statistical
findings) can be found in <xref rid="SD1" ref-type="supplementary-material">Online Supplemental Material 1</xref>. Unmatched survey data reflect
participants who completed the pre- and post-training surveys. The
Mann-Whitney U test (unmatched ordinal data) or the Wilcoxon Rank Sum test
(matched data) were used with alpha set at 0.05.</p><p id="P19">Surveys for PPSNE and BMC were distributed via Qualtrics or paper
surveys (pre-pandemic); PPGNHAIK&#x02019;s surveys were distributed via the
health center&#x02019;s online learning management system. Pre- and
post-training surveys were administered; unmatched samples measured changes
in these factors and reported practice behaviors in participating providers.
At BMC, 262 pre-training surveys were completed representing all 12
participating sites and 49 post-training surveys were completed 3&#x02013;6
months post-training, representing five participating sites. At PPSNE, 140
pre-training surveys were completed representing all 15 health centers and
56 post-training surveys representing 12 centers were completed
approximately 6 months after training. Data from PPGNHAIK comprised 198
pre-training surveys and 139 post-training surveys.</p><p id="P20">Qualitative data analysis allowed for triangulation of information
from stakeholders through focus groups, key informant interviews, document
review, and observations. Qualitative data was collected and analyzed by
trained evaluators through a variety of strategies across sites including
semi-structured interviews and focus groups. Site-specific Institutional
Review Board approvals guided data collection with most interviews audio
recorded and transcribed; in the absence of recording, detailed notes were
taken. Semi-structured interview protocols were guided by implementation
science and evaluation frameworks (e.g., the Consolidated Framework for
Implementation Research).<sup><xref rid="R11" ref-type="bibr">11</xref></sup> The interview guides included questions related to
protocols and workflows, internal and external contextual factors, patient
interactions and provider self-efficacy, and barriers and facilitators to
practice change. Convenience sampling was used to identify stakeholders who
had relevant perspectives. Interview data were analyzed using thematic
analysis.<sup><xref rid="R18" ref-type="bibr">18</xref></sup>
Content was coded by topic area and analyzed in Excel or NVIVO. Common
themes that emerged across all programs, and site-specific themes uncovered
during meetings and discussion, were included in the cross-site
evaluation.</p></sec></sec></sec><sec id="S14"><title>Results</title><sec id="S15"><title>Systems-Level Implementation Outcomes.</title><p id="P21">Using the process-related outcomes identified in the logic model (<xref rid="F1" ref-type="fig">Figure 1</xref>), systems-level implementation
outcomes were measured via a variety of data collection strategies (<xref rid="T1" ref-type="table">Table 1</xref>). Program-based components of the
SBIRT Program Matrix included: performance site descriptions, providers and
workflow; management structure, program receptivity and leadership involvement;
training format and content; use of technology; and program evaluation and
dissemination. Pandemic-driven changes, adaptations, or enhancements in service
delivery or clinic needs were identified through process evaluations (<xref rid="T2" ref-type="table">Table 2</xref>).</p><sec id="S16"><title>Risk Factors Addressed and SBI Services.</title><p id="P22">Although variation across programs in their implementation of
alcohol SBI services existed, similarities emerged in targeting risk factors
(alcohol and other substances) and services performed. All programs
implemented evidence-based alcohol and drug SBI protocols, including
prescreens (USAUDIT-C,<sup><xref rid="R19" ref-type="bibr">19</xref></sup>
Single Item Screening Questions for Drug<sup><xref rid="R20" ref-type="bibr">20</xref></sup> and Alcohol<sup><xref rid="R21" ref-type="bibr">21</xref></sup> use), full screens (USAUDIT,<sup><xref rid="R19" ref-type="bibr">19</xref></sup> WHO AUDIT,<sup><xref rid="R22" ref-type="bibr">22</xref></sup> DAST-10,<sup><xref rid="R23" ref-type="bibr">23</xref></sup> ASSIST-FC<sup><xref rid="R24" ref-type="bibr">24</xref></sup>), brief interventions (motivational
interviewing style, brief negotiated interview,<sup><xref rid="R25" ref-type="bibr">25</xref></sup> FRAMES<sup><xref rid="R26" ref-type="bibr">26</xref></sup>) and EHR-integrated referral
procedures to local substance use disorder treatment services.</p></sec><sec id="S17"><title>Performance Programs, Providers, and Workflow.</title><p id="P23">All programs provided preventive, primary, reproductive and
gender-affirming care in diverse, underserved communities but with varying
workflows and types of providers involved in care. At three of the four
programs, clinicians conducted brief intervention following patient
self-administered screening and electronic scoring or scoring by medical
assistants. In one program (HFH), an interactive computer-based SBI program
was used, supported by EHR best practice alerts for clinicians interacting
with patients with moderate- or high-risk alcohol consumption.</p></sec><sec id="S18"><title>Management Structure, Receptivity, and Leadership Involvement.</title><p id="P24">Health systems with a centralized management structure (PPGNHAIK,
PPSNE, HFH) were associated with a higher level of receptivity to SBI
implementation and greater initial leadership involvement. Health centers
independently managed within the system (BMC) experienced varying levels of
receptivity in community health centers, necessitating further engagement
strategies for buy-in.</p></sec><sec id="S19"><title>Training Format and Content.</title><p id="P25">Training format and content was similar across programs, before and
during the pandemic. Pre-pandemic, most programs included in-person
presentation-style education incorporating skills-building, practice,
role-play, and video demonstrations, with a focus on preventing AEPs and
FASDs. During the pandemic, all programs transitioned to live video
synchronous training with three programs shifting to web-based asynchronous
training. The fourth program provided support and continued technical
assistance via virtual consultation. In three programs, training content was
formalized and incorporated into health systems&#x02019; learning management
system for sustainability and delivered using technology-based engagement
strategies with some variation in systemization of adaptations due to health
center disruptions. For example, when a state of emergency was declared,
in-person experiences were limited to emergency- or essential-workers only,
clinics temporarily shut down or closed, and shifts in protocols and
workflows followed. Other disruptions included clinics adapting to
technology-based care using telehealth, staff shortages, staff reallocation,
and deployment of trained staff to other functions.</p></sec><sec id="S20"><title>Trained Staff.</title><p id="P26">Across all programs, 1,259 individuals were trained in alcohol SBI
service delivery representing: clinicians (physicians, physician assistants,
nurse practitioners, certified nurse-midwives, and behavioral health
clinicians; n=340); licensed and registered nurses and medical assistants
(n=403); administrative and front desk staff (n=191); non-clinical
leadership, including health system and/or project staff trainers (n=84);
and other types of providers (n=5) (<xref rid="T3" ref-type="table">Table
3</xref>). These numbers represent unique individuals trained even
though a majority attended multiple trainings (e.g., tailored follow-up
training). Technical assistance was provided to health centers and providers
based on identified need.</p></sec><sec id="S21"><title>Use of Technology.</title><p id="P27">Two programs incorporated screening assessments in the EHR when
electronic check-in was performed. EHRs were modified to accommodate
screening scores, facilitate documentation of brief intervention, and
provide clinical decision support, including facilitating referrals and
billing processes. One program incorporated automated patient education
materials. Technology was used to support SBI services, including
integration of training videos and materials in two programs&#x02019;
learning management system and, in one program, the development and
dissemination of a podcast to educate providers on FASDs. One program
delivered SBI services through the Computerized Intervention Authoring
System program, fully integrated with the EHR to capture SBI delivery.</p></sec><sec id="S22"><title>Program Evaluation and Dissemination.</title><p id="P28">Program evaluation and dissemination efforts included utilizing
de-identified EHR data to monitor program performance and provide regular
feedback to stakeholders, relying on already established electronic systems,
pre-existing collaborations and partnerships, project-specific data
dashboards, and routine opportunities for meetings and feedback
mechanisms.</p></sec></sec><sec id="S23"><title>Provider-Level Outcomes.</title><p id="P29">Provider-level implementation outcomes were measured across all
programs.</p><sec id="S24"><title>Practice Change Behaviors:</title><p id="P30">Intermediate provider-specific practice changes, serving as proxies
for longer-term change,<sup><xref rid="R27" ref-type="bibr">27</xref></sup>
were evaluated in three of the four programs (PPGNHAIK, PPSNE, BMC)
including: 1) self-reported assessment of skills in providing SBI services;
2) attitudes about the importance of conducting SBI services; 3)
self-efficacy/confidence in conducting SBI activities; 4) readiness to
change practice behavior; 5) training satisfaction; and, 6) knowledge about
alcohol use limits and effects on pregnancy. Results below summarize a
larger sample of questions; more details are available in <xref rid="SD1" ref-type="supplementary-material">Online Supplemental Material
1</xref>.</p><sec id="S25"><title>Skills</title><p id="P31">Skill assessment across programs (PPSNE, BMC) ranged from
questions on perceived <italic toggle="yes">effectiveness</italic> and
<italic toggle="yes">preparedness</italic> to self-rated <italic toggle="yes">ability</italic>
to conduct behavioral counseling services for risky alcohol or other
drug use. Pre- and post-training responses with unmatched samples showed
significant increases in staff&#x02019;s skills assessment: increases in
<italic toggle="yes">preparedness</italic> to talk to patients about reducing
their alcohol consumption; increased self-rated <italic toggle="yes">ability to
counsel</italic> patients about the risks of PAE; and, increased
self-rated <italic toggle="yes">ability to perform a brief intervention</italic> for
risky alcohol use.</p></sec><sec id="S26"><title>Attitudes</title><p id="P32">Two programs (PPSNE, BMC) assessed changes in attitudes before
and after trainings. Changes in attitudes did not differ significantly
for some measures, including providers&#x02019; attitudes about the
<italic toggle="yes">importance</italic> of talking to patients about reducing
their alcohol use (PPSNE). The <italic toggle="yes">importance</italic> of educating
patients about the risks of PAE in routine care significantly decreased
among respondents BMC. There was a significant decrease from
pre-training to post-training in staff&#x02019;s beliefs that patients
will get angry or annoyed if they advise them about their drinking.
While attitudes can be immediately impacted by a training leading to
behavior change, provider attitudes were generally positive prior to
training.</p></sec><sec id="S27"><title>Self-Efficacy</title><p id="P33">Programs measuring self-efficacy and confidence (PPGNHAIK,
PPSNE) exhibited significant increases from pre-training to
post-training in staff&#x02019;s confidence to perform SBI activities
(<xref rid="SD1" ref-type="supplementary-material">Online
Supplemental Material 1</xref>). These were assessed through
questions including <italic toggle="yes">confidence</italic> to ask questions about a
patient&#x02019;s risk for alcohol-related problems;
<italic toggle="yes">confidence</italic> in providing patients with educational
materials to help them reduce their drinking; improvement of their
skills to ask female-bodied individuals, including pregnant individuals,
about their alcohol use; and, improvement of their skills to educate
individuals of reproductive age, including those who are pregnant, about
the effects of alcohol on a developing fetus.</p></sec><sec id="S28"><title>Readiness to Change</title><p id="P34">One site (BMC) measured readiness to change post-training,
finding that 84.8% of providers agreed that communication with their
patients about excessive alcohol use will change and 64.8% of providers
indicated that they would implement skills in practice (screening
patients for alcohol use, performing a brief intervention for excessive
alcohol use, counseling patients about the risks of PAE, communicating
information on FASDs to patients, and applying the core principles of
motivational interviewing). Commonly-reported challenges to change were
patient resistance (53.8%), lack of support to staff to help make
changes (24.4%), or not a priority given limited time (21.8%).</p></sec><sec id="S29"><title>Training Satisfaction</title><p id="P35">Satisfaction indicators monitored acceptability and engagement
in the trainings and program activities. Two programs (PPGNHAIK, BMC)
found that providers agree that the trainings enhanced their skills and
knowledge. For example, providers at PPGNHAIK <italic toggle="yes">agreed</italic>
that they were satisfied with their experience and agreed the training
enhanced their professional expertise. Almost all BMC providers agreed
that the training gave them valuable skills (91.7%) or knowledge (90.4%)
to use in practice and were satisfied with the training (93.1%).</p></sec><sec id="S30"><title>Knowledge</title><p id="P36">In this evaluation, baseline knowledge on many indicators was
high, as expected in a well-established provider population, but offered
room for improvement around general FASD knowledge, the steps to conduct
an appropriate brief intervention, and recommended drinking guidelines.
For example, pre-training, 42.0% of providers correctly identified the
definition of excessive drinking for non-pregnant female-bodied
individuals aged 21 and over, increasing to 79.0% post-training
(PPGNHAIK). At PPSNE.0, 76.8% and 92.3% of staff correctly identified
excessive alcohol use pre-training and post-training, respectively.</p><p id="P37">Recognizing that providers operate within a larger system that
may impede practice changes, clinic workflows and protocols were
assessed to identify facilitators and barriers to providers&#x02019;
training competencies. This included long-term integration of SBI
protocols and expansion; billing processes and facilitators;
standardization of referral procedures; staff roles, responsibilities,
and connection to clinic workflow; EHR experiences, facilitators, and
barriers to documentation and data availability; and, adoption and
implementation of electronic SBI within the larger system.</p><p id="P38">To monitor SBI service delivery in the practice settings,
including changes over the course of the programs, standardized
quarterly data were reported to the CDC, obtained via de-identified EHR
data that captured alcohol and other drug screening, brief intervention,
and referral rates.</p></sec></sec><sec id="S31"><title>Performance Outcomes.</title><p id="P39">SBIRT service data were obtained from EHR records and used to
measure program performance with 48 health centers reporting data across the
four programs (<xref rid="T4" ref-type="table">Table 4</xref>). Three
programs (PPGNHAIK, PPSNE, BMC) provided data for 36 months (July 1, 2019
through June 30, 2022); HFH began 18 months later on January 1, 2021. The
target population were individuals aged 18 and older, presenting for an
annual, preventive, or reproductive health care visit (308,938 individuals,
ranging from 3,079 to 268,651). Populations served and screening information
was tracked across years for comparison within each program, not across
programs. The proportion of the target population screened for alcohol use
ranged from 9.0% (HFH) to 89.5% (PPGNHAIK) across programs with 106,826
patients screened. The proportion of patients who screened positive for
excessive alcohol use (n=10,087) ranged from 7.8% (BMC) to 26.7% (HFH).
Programs had varying proportions of patients scoring in the high-risk range
for alcohol use. All programs tracked BIs that were conducted for
<italic toggle="yes">either</italic> alcohol or another substance. Proportions of
those who screened positive for <italic toggle="yes">any</italic> substance who received
a brief intervention ranged from 13.7% (BMC) to 61.5% (PPGNHAIK). Where
possible, programs reported on screening, alcohol-only brief intervention,
and referral rates for substances other than alcohol (<xref rid="T4" ref-type="table">Table 4</xref>).</p></sec><sec id="S32"><title>Patient Characteristics.</title><p id="P40">Patient characteristic categories for race and ethnicity are
reported in the manner in which they were collected from their collaborating
health centers/sites. Three programs served predominantly female patients
(97%&#x02212;100%), while one (BMC) served more male patients (52.5%) (<xref rid="T5" ref-type="table">Table 5</xref>) with mean ages between 29 and
34 years old. HFH served a majority Black/African American (72.0%)
population while PPGNHAIK served a majority White (68.6%) population.
PPSNE&#x02019;s patient population was primarily White (46.1%) but with the
largest Hispanic population (24.7%) across programs, while BMC&#x02019;s
patient profile was 37.1% Black/African American and 24.6% White. Within the
two Planned Parenthood affiliates, approximately 42% of patients received
public assistance.</p></sec></sec></sec><sec id="S33"><title>Discussion</title><p id="P41">Successful implementation of systems-level change, such as alcohol SBI, is
essential, especially in the context of an ongoing pandemic. While these changes are
not often evaluated at the systems level, there are known barriers, including
limited time and competing demands for providers<sup><xref rid="R28" ref-type="bibr">28</xref></sup>; lack of necessary systems-level supports; and, clinician
beliefs, experiences, and self-efficacy when discussing alcohol use with
patients.<sup><xref rid="R29" ref-type="bibr">29</xref></sup> Efforts to
systematically address these barriers are relatively new and untested and may be met
with skepticism or apprehension if they are perceived as disruptive to existing
clinical operations. This program provided the opportunity to evaluate and summarize
facilitators and barriers to implementation of SBI efforts across systems. Given the
differences in context, complexity of program delivery, variety of data sources, and
analysis plans, the SBIRT Program Matrix<sup><xref rid="R10" ref-type="bibr">10</xref></sup> was used to organize implementation factors of focus of the
cross-site evaluation. This framework facilitated aggregation of information,
including facilitators and barriers, which impacted systems- and provider-level
outcomes.</p><sec id="S34"><title>SBI Services.</title><p id="P42">The adoption of standardized SBI service protocols and uptake across 53
health centers demonstrates successful implementation and reach. Protocol
adaptations across settings, clinics, and in response to external factors
improved acceptability, feasibility, and appropriateness of implementation.
Comparing SBI outcomes is difficult and must consider implementation factors
that include setting type (hospital, primary care clinic), population density
(urban, rural), provider type (medical assistant, clinician) and relative
priority (leadership).<sup><xref rid="R30" ref-type="bibr">30</xref></sup> And,
although screening rates reported here vary from 9.0% - 89.5%, the programs
collectively screened a large number of patients using validating screening
instruments and protocols (106,826 patients over 5 years).</p><p id="P43">The COVID-19 pandemic caused about six months of disruption in the
implementation and evaluation of programs. Pivoting to online and virtual
formats for training, technical assistance, assessment, and delivery of the
brief intervention changed the originally-planned protocols but facilitated
continuation of services. Furthermore, leveraging EHR and other technology
resulted in more efficient data collection. Measurement and reporting evolved as
the process evaluation informed program course corrections and modifications to
provider workflows. All programs were successful in adapting their
implementation approaches while maintaining adherence to the protocols. The
adoption of virtual training formats has shown promise in other related studies
as well. For example, in a recent study<sup><xref rid="R31" ref-type="bibr">31</xref></sup> of SBIRT training for social workers, those trained
online showed increases in SBIRT practice, confidence, and sense of
responsibility. Virtual training has clear benefits to health systems; benefits
reported here among reproductive health care providers have been similarly
demonstrated in other disciplines<sup><xref rid="R32" ref-type="bibr">32</xref></sup> during the pandemic. Virtual training is a critical feature
for sustainability of these efforts.</p></sec><sec id="S35"><title>Performance programs.</title><p id="P44">Existing literature shows that primary care programs are feasible
locations for SBI services and somewhat effective at reducing excessive drinking
among patients.<sup><xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R33" ref-type="bibr">33</xref>&#x02013;<xref rid="R35" ref-type="bibr">35</xref></sup> However, previous studies indicate that reproductive
and women&#x02019;s health providers are less likely than other clinicians to
conduct SBI.<sup><xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R37" ref-type="bibr">37</xref></sup> The high rates of screening and brief
intervention at two reproductive care systems in this project demonstrate the
feasibility of SBI when implementation is supported with training and quality
improvement feedback.</p></sec><sec id="S36"><title>Patient attributes.</title><p id="P45">The target population of focus for this project was patients attending
primary and reproductive healthcare settings to reduce excessive alcohol use in
individuals who could become pregnant. Accordingly, the population was
predominantly females of reproductive age; however, programs reflected a
racially- and ethnically-diverse mix of patients. Previous research demonstrates
effectiveness and efficacy outcomes of SBI are mixed and vary by population,
risk levels, and substance type.<sup><xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R38" ref-type="bibr">38</xref></sup> Further
understanding of the ways that patient characteristics may influence
implementation, acceptability, and overall program success is warranted.</p></sec><sec id="S37"><title>Management structure and activities.</title><p id="P46">Consistent with the literature,<sup><xref rid="R14" ref-type="bibr">14</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R33" ref-type="bibr">33</xref>&#x02013;<xref rid="R35" ref-type="bibr">35</xref></sup> readiness for implementation, leadership support, and
the ability to use available resources (especially IT and EHR platforms) were
common factors that supported the implementation and evaluation of SBI in
primary care practices. Having leadership champions at both system- and
clinic-levels facilitated uptake of the SBI protocol and collection of
evaluation data. While sometimes a strength, the ability to use and reliance on
technology and EHRs come with inherent limitations: a lack of interoperability;
inability to collect data as specified within the evaluation metrics; delays due
to systems upgrades; relying on IT staff to query and deliver the data; and,
competing demands within health systems that may delay changes or data delivery,
all of which can impact the ability to evaluate the effectiveness of an
intervention because of potential issues with data integrity. Consistent
terminology and open lines of communication between project members minimized
these impacts.</p><p id="P47">Developing and maintaining continuous feedback loops between program and
evaluation teams is a demonstrated strategy to facilitate successful
implementation.<sup><xref rid="R35" ref-type="bibr">35</xref></sup>
While there were nuances, each program used regular reflection and data reviews
to provide ongoing feedback to clinic staff and stakeholders, including data
dashboards showing screening and brief intervention rates by clinic, quarterly
reviews of data, monitoring click-through rates on web-based information links,
and/or EHR flags or best practice alerts. Consistent with previous research,
this regular feedback supported successful implementation, enabling the teams to
course-correct and to be as responsive as possible to clinician concerns
regarding SBI implementation.</p></sec><sec id="S38"><title>Provider characteristics.</title><p id="P48">Using evaluation data and learnings around provider knowledge and
beliefs can help improve the process of SBI implementation and in particular
patterns in uptake and acceptability.<sup><xref rid="R39" ref-type="bibr">39</xref></sup> Knowledge arms providers with relevant information and
new research, corrects misperceptions, and enables understanding of the larger
landscape of FASDs and their role in discussions with their patients. In all
programs, standard SBI training protocols incorporated information about FASD
risks and prevention of AEPs. Pre- and post-test surveys assessed baseline and
changes in knowledge and perceptions about the need for SBI, demonstrating
provider intention to change behavior. Assessing this is important given that
improvements in confidence and self-efficacy to perform a behavior combined with
skills to execute the behavior can lead to successful behavior change in
practice.<sup><xref rid="R27" ref-type="bibr">27</xref></sup></p></sec></sec><sec id="S39"><title>Limitations</title><p id="P49">There are some limitations in this cross-site evaluation. First, it was not
possible to assess the patient perspective and outcomes within the study timeframe.
Patient experiences could offer more nuanced explanations for successful engagement,
uptake with SBI, and effectiveness. Second, while many evaluation factors were
consistent, some programs used different assessment tools, survey questions, and
data collection strategies to fit their context and resources. Third, there was
limited ability to link the providers trained with the data in the EHR thereby
reducing our ability to link training to SBI metrics. Fourth, programs had varying
degrees of SBI trainings and activities before the funding. Fifth, there was a
reliance on secondary data collected by collaborating organizations and/or the EHR
leading to some incomplete data. Finally, follow-up evaluation activities were
limited due to resources, lack of response, and competing priorities for provider
time.</p></sec><sec id="S40"><title>Conclusion</title><p id="P50">Evaluation of multi-site, systems-based efforts is complicated, especially
when the activities and implementation of those activities differ based on the
programs&#x02019; context, resources, internal organizational structure, and other
factors. Having resources and leadership support are key to system-wide
change.<sup><xref rid="R14" ref-type="bibr">14</xref></sup> Despite the
hypothesized and proven benefits of alcohol SBI, adoption of these programs within
established healthcare settings can be challenging, potentially more so with
pandemic-related increases in substance use and shifts in clinic protocols. This
cross-site evaluation explored and described barriers and facilitators to SBI
implementation efforts and effectiveness on systems-level and provider outcomes.
Evaluations of systems-based approaches to support provider behavior in delivering
SBI are essential to understanding best practices for delivery and achieving
positive outcomes in patients. Such evaluations are even more useful for large-scale
adoption and adaptation when a variety of contexts are examined.</p></sec><sec sec-type="supplementary-material" id="SM1"><title>Supplementary Material</title><supplementary-material id="SD1" position="float" content-type="local-data"><label>Supplemental Material 1</label><media xlink:href="NIHMS2025665-supplement-Supplemental_Material_1.docx" id="d67e598" position="anchor"/></supplementary-material></sec></body><back><ack id="S41"><title>Acknowledgements.</title><p id="P51">The authors wish to acknowledge our partners and collaborators at Planned
Parenthood Great Northwest, Hawai&#x02019;i, Alaska, Indiana, Kentucky; Planned
Parenthood of Southern New England; Boston Medical Center Clinical Data Warehouse,
Boston Medical Center, and Boston HealthNet Health Centers; and Henry Ford Health,
Michigan State University, Wayne State University.</p><p id="P52"><bold><italic toggle="yes">Funding.</italic></bold> All sites and authors were supported
by cooperative agreements from the Centers for Disease Control and Prevention
awarded under CDC-RFA-DD18&#x02013;1802: [grant numbers NU84DD000001 (HFH),
NU84DD000002 (BMC), NU84DD000004 (UCH), NU84DD000005 (UAA)]. The supporting
organization had no further role in the design; in the collection, analysis, and
interpretation of the data; or in writing the manuscript.</p></ack><fn-group><fn fn-type="COI-statement" id="FN2"><p id="P53"><bold><italic toggle="yes">Declaration of Conflicting Interests</italic></bold>. The
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Model</title></caption><graphic xlink:href="nihms-2025665-f0001" position="float"/></fig><fig position="float" id="F2"><label>Figure 2.</label><caption><title>Sample Questions That Assessed Provider Skills, Knowledge, Attitudes,
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(n=4)</title></caption><graphic xlink:href="nihms-2025665-f0002" position="float"/></fig><table-wrap position="float" id="T1"><label>Table 1.</label><caption><title>Data Sources by Program</title></caption><table frame="box" rules="all"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th align="left" valign="bottom" rowspan="1" colspan="1"/><th align="center" valign="top" rowspan="1" colspan="1">University of Alaska Anchorage Center for
Behavioral Health Research Services (UAA)</th><th align="center" valign="top" rowspan="1" colspan="1">University of Connecticut School of Medicine
at UConn Health (UConn Health)</th><th align="center" valign="bottom" rowspan="1" colspan="1">Boston University School of Public Health
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informal notes, observations, etc.)</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Secondary Data Sources (i.e., technical
assistance documents, user interface data, etc.)</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Environmental Scan</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1">X</td><td align="center" valign="top" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Pre, Post, Follow-Up Surveys</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Key Informant Interviews</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Focus Groups/Group Interviews</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Site Visits</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1">X</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Training Rosters/Attendance Records</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Training Observation Forms</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Program Electronic Health Record Tracking
Data</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1">X</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Podcast Metric Data</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Continuing Medical Education Credit Data</td><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1"/><td align="center" valign="bottom" rowspan="1" colspan="1">X</td><td align="center" valign="bottom" rowspan="1" colspan="1"/></tr></tbody></table></table-wrap><table-wrap position="float" id="T2" orientation="landscape"><label>Table 2.</label><caption><title>Systems-level Implementation Outcomes by Program</title></caption><table frame="box" rules="all"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th colspan="2" align="center" valign="bottom" rowspan="1">Funded Recipient &#x00026;
Clinical Partner</th><th align="center" valign="top" rowspan="1" colspan="1">University of Alaska Anchorage Center for
Behavioral Health Research Services (UAA) &#x00026; Planned Parenthood Great
Northwest, Hawai&#x02019;i, Alaska, Indiana, Kentucky (PPGNHAIK)</th><th align="center" valign="middle" rowspan="1" colspan="1">University of Connecticut School of
Medicine at UConn Health (UConn Health) &#x00026; Planned Parenthood of
Southern New England (PPSNE)</th><th align="center" valign="bottom" rowspan="1" colspan="1">Boston University School of Public Health
(BUSPH) &#x00026; Boston HealthNet, Boston Medical Center (BMC)</th><th align="center" valign="bottom" rowspan="1" colspan="1">Center for Health and Research
Transformation (CHRT) &#x00026; Henry Ford Health (HFH)</th></tr></thead><tbody><tr><td colspan="2" align="center" valign="top" rowspan="1">
<bold>Risk Factors
Addressed</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">Alcohol, drug use</td><td align="center" valign="bottom" rowspan="1" colspan="1">Alcohol, drug use</td><td align="center" valign="bottom" rowspan="1" colspan="1">Alcohol, pregnancy, drug use</td><td align="center" valign="bottom" rowspan="1" colspan="1">Alcohol, pregnancy, drug use</td></tr><tr><td rowspan="4" align="center" valign="middle" colspan="1">
<bold>SBIRT
Services</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<italic toggle="yes">Pre-screen</italic>
</td><td align="center" valign="top" rowspan="1" colspan="1">USAUDIT-C</td><td align="center" valign="top" rowspan="1" colspan="1">USAUDIT-C</td><td align="center" valign="top" rowspan="1" colspan="1">SISQ (Drug and Alcohol)</td><td align="center" valign="top" rowspan="1" colspan="1">NIDA Quick Screen</td></tr><tr><td align="center" valign="bottom" rowspan="1" colspan="1">
<italic toggle="yes">Full screen</italic>
</td><td align="center" valign="top" rowspan="1" colspan="1">USAUDIT<break/>DAST-10</td><td align="center" valign="top" rowspan="1" colspan="1">USAUDIT<break/>ASSIST-FC</td><td align="center" valign="top" rowspan="1" colspan="1">AUDIT (WHO version)<break/>DAST-10</td><td align="center" valign="bottom" rowspan="1" colspan="1">USAUDIT-C</td></tr><tr><td align="center" valign="bottom" rowspan="1" colspan="1">
<italic toggle="yes">Brief Intervention
Approach</italic>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">Motivational Interviewing, FRAMES</td><td align="center" valign="bottom" rowspan="1" colspan="1">Brochure-driven, Motivational
Interviewing, FRAMES</td><td align="center" valign="bottom" rowspan="1" colspan="1">Brief Negotiated Interview, Motivational
Interviewing</td><td align="center" valign="top" rowspan="1" colspan="1">e-brief intervention provided to those who
screen positive; e-brief intervention messaging tailored by risk
profile; Motivational interviewing</td></tr><tr><td align="center" valign="bottom" rowspan="1" colspan="1">
<italic toggle="yes">Referral to
Treatment</italic>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">EHR-integrated referral procedures,
vetted referral lists to local SUD treatment agencies</td><td align="center" valign="bottom" rowspan="1" colspan="1">EHR-integrated referral procedures,
vetted referral lists to local SUD treatment agencies</td><td align="center" valign="top" rowspan="1" colspan="1">EHR-integrated referral procedures, referral
to specialists and resources per clinic protocols, warm hand-off to
behavioral health</td><td align="center" valign="bottom" rowspan="1" colspan="1">BPA in EHR during visit; referral to HFH
behavioral health as accepted by patient</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Performance
Programs</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">24 health centers providing reproductive
and sexual health services in Alaska, Hawai&#x02019;i, Idaho, and
Washington state.</td><td align="center" valign="bottom" rowspan="1" colspan="1">15 health centers providing reproductive,
gender-affirming, preventive and primary care services in Connecticut
and Rhode Island; 2 Patient-Centered Medical Home (PCMH) certified.</td><td align="center" valign="top" rowspan="1" colspan="1">11 health centers; Boston Medical Center
(BMC) and 10 Boston HealthNet Community Health Centers (CHC), which
include 33 practices in Boston and surrounding communities providing
integrated health care.</td><td align="center" valign="bottom" rowspan="1" colspan="1">3 women&#x02019;s health clinic sites in
southeastern (Detroit and metropolitan area) and southcentral
Michigan.</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Providers and SBIRT
Workflow</bold>
</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; Screening questions
self-administered during Mobile Check-In (patient&#x02019;s phone or
clinic iPad)<break/>&#x02022; If paper format, front desk staff/medical
assistant enters screening results into EHR<break/>&#x02022; If
indicated, clinician (physician assistant, nurse practitioner,
physician) provides BI and documents need for referral in
EHR<break/>&#x02022; Provider or referral coordinator links patients to
external services as needed</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; Screening questions
self-administered in waiting room (pencil and paper)<break/>&#x02022;
Clinic assistant tallies responses and enters scores into EHR; verbally
conveys results to clinician<break/>&#x02022; Clinician (nurse
practitioner, physician assistant, certified nurse midwives) conducts BI
during clinical visit; documented in EHR via SBI order set which also
facilitates billing<break/>&#x02022; Referrals made by clinician or
health center manager as needed; documented in EHR</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Screening questions self-administered
before provider visit (pencil and paper or
electronically)<break/>&#x02022; If paper format, medical assistant
tallies responses and enters scores into EHR; verbally conveys results
to clinician<break/>&#x02022; Clinician (primary care physicians, nurse
practitioners) conducts BI during clinical visit; documented in EHR (BI
checkbox, free text notes)<break/>&#x02022; Referrals made by clinician
as needed via warm hand-off or clinic protocol; documented in EHR</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; Screening questions
self-administered via iPad while waiting for wellness visit on the day
of appointment or as a &#x02018;direct-to-patient&#x02019; link sent prior
to appointment<break/>&#x02022; Results uploaded to EHR; a BPA is issued
prompting referral or follow-up<break/>&#x02022; Patients offered
educational videos and informational resources about risk and alcohol
consumption; motivational interviewing techniques are incorporated into
eSBI protocol</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Management Structure,
Receptivity, and Leadership Involvement</bold>
</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Centralized clinical operations
support, EHR, training, quality assurance and
decision-making<break/>&#x02022; Affiliate leadership receptive to SBI
expansion<break/>&#x02022; Multidisciplinary planning team met
semi-monthly throughout planning and implementation
phases<break/>&#x02022; Planning team included affiliate leadership,
clinical operations staff, clinicians, and quality assurance,
informatics, and training staff</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Centralized clinical operations
support, EHR, training, quality assurance and decision-making; center
managers provide on-site clinical support; regional directors provide
quality assurance oversight; training and education department maintain
patient care standards<break/>&#x02022; Affiliate leadership receptive to
adopting alcohol SBI and collaborated on funding
application<break/>&#x02022; Multidisciplinary implementation planning
team included staff in clinical operations, grants management, training
and evaluation, strategic healthcare initiatives and program management;
PPSNE leadership engaged health center managers to serve as site
champions and assist in organizing and managing the program at their
health centers</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; CHCs are independently managed with
individual fiscal management, administrative staff and clinical
leadership<break/>&#x02022; Boston HealthNet leadership supportive of
alcohol SBI implementation; however, with little influence over CHCs,
receptivity ranged from none to highly interested<break/>&#x02022;
Engagement strategies targeted Boston HealthNet management, grand round
coordinators, CME course directors, and medical and behavioral health
directors; included presentations on alcohol SBI, prenatal alcohol
exposure and FASDs; tailored education, training and technical
assistance was offered to interested CHCs</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Mixed management structure; health
systems level is centralized, top-down administrative leadership;
operations among clinics vary in management structure<break/>&#x02022;
HFH receptive to integrating technology-based alcohol SBI as universal,
standardized screening was not occurring; strong interest in integrating
primary and behavioral health care<break/>&#x02022; Physicians in
leadership roles and information technology leaders served as champions
to assist in planning, implementation procedures and troubleshooting
problems. Clinic managers were engaged as on-site champions and single
points of contact to troubleshoot and encourage participation</td></tr><tr><td colspan="2" align="center" valign="top" rowspan="1">
<bold>Training
Format</bold>
<break/>
<bold>(including COVID-19 pandemic-related
adaptations)</bold>
</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Phased, staggered on-site training
for each health center<break/>&#x02022; Hybrid of online training modules
followed by half-day, in-person training facilitated by PowerPoint
presentations. Training included role-play vignettes, training videos,
and skills practice activities<break/>&#x02022; After COVID-19 limited
in-person meetings: transitioned to online format via
organization&#x02019;s internal learning management system, followed by a
distance-format skills practice activities (asking questions,
role-playing)<break/>&#x02022; Training followed by qualitative feedback
sessions with staff to address problems as they arose</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Staggered training for each health
center, with roll-out targeting larger health centers
first<break/>&#x02022; In-person training sessions facilitated by Power
Point presentations, practice, and role-play activities<break/>&#x02022;
After COVID-19 limited in-person meetings: transitioned to virtual,
on-line training sessions facilitated by Power Point presentations with
role-play activities held on site by clinic staff trainer with live
trainers available online for support<break/>&#x02022; Transitioned to
recorded presentations with role-play activities held on site by clinic
staff trainer with live trainers online for support</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; In-person training sessions
facilitated by Power Point presentations, practice and role-play
vignettes, training videos, and resource cards<break/>&#x02022; After
COVID-19 limited in-person meetings: transitioned to virtual, on-line
training sessions facilitated by Power Point presentations hosted on
Zoom using polling, chat, videos, breakout rooms, modeling, and with
live support<break/>&#x02022; Implemented broader reach trainings through
podcast with survey, lunch and learns, and qualitative feedback sessions
with clinic leadership</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; A series of meetings and trainings
with each clinic leading up to and following implementation of alcohol
SBI.<break/>&#x02022; At the provider level, focused e-learning modules
provided to ensure consistent understanding of the importance of alcohol
SBI and of their role in carrying it out.<break/>&#x02022; Ongoing
technical assistance and support provided as needed<break/>&#x02022;
Regular meetings and performance reports to trouble-shoot and facilitate
adjustments to implementation<break/>&#x02022; At the beginning of the
pandemic (March 2020), the State of Michigan was under emergency orders
to close all non-essential work and businesses, including in health
care. HFH was closed for routine, ambulatory care visits for several
months. This delayed implementation as in-person visits were generally
impossible. As the health system ramped up telehealth visits, the eSBI
was adapted so it was available to patients through the HFH patient
portal prior to their scheduled visit. This adaptation has been
incorporated into the overall implementation plan going forward.</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Health Center/Clinic
Staff Training Content</bold>
</td><td align="left" valign="top" rowspan="1" colspan="1">Training modules included:<break/>&#x02022;
Risks of substance use during pregnancy<break/>&#x02022;
FASDs<break/>&#x02022; Preventing substance-exposed
pregnancies<break/>&#x02022; Reasons SBI is being adopted
system-wide<break/>&#x02022; SBI utility and history<break/>&#x02022; How
and when to conduct screening, make referrals<break/>&#x02022; What SBI
workflows in the clinic look like</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Starting with CDC&#x02019;s
Collaborative for Alcohol-free Pregnancy&#x02019;s online training, all
staff participated in 4 additional training modules <break/>&#x02022;
Overview and Rationale for Alcohol SBI, including preventing
substance-exposed pregnancies and FASDs<break/>&#x02022; Screening for
Substance Use<break/>&#x02022; Brief Intervention
Techniques<break/>&#x02022; SBIRT Workflow<break/>&#x02022; EHR
documentation and billing for SBI<break/>&#x02022; Technical
assistance/booster sessions provided as needed after 6-week performance
audit</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; All staff received initial training
together to establish baseline knowledge of FASDs, and how alcohol SBI
fit into their practice <break/>&#x02022; Healthcare teams trained using
existing educational venues (e.g., business meetings, grand rounds), and
subsequent trainings were targeted to roles (providers, nurses,
behavioral health, medical assistants) and additional related areas of
interest (AUD treatment, adolescent alcohol use), and tailored by
site<break/>&#x02022; Technical assistance was provided based on
additional needs and gaps in workflow as identified through surveys and
follow-up discussions with sites</td><td align="left" valign="bottom" rowspan="1" colspan="1">Additional trainings conducted to
familiarize clinic leadership and staff with CIAS platform for eSBI
delivery</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Use of
Technology</bold>
</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; EHR: NextGen&#x000ae;
<break/>&#x02022; Screening instruments incorporated into visit check-in
protocols (on paper and via electronic check in)<break/>&#x02022; Changes
made to EHR to facilitate the brief intervention and
documentation<break/>&#x02022; Training materials included in
PPGNHAIK&#x02019;s online Learning Management System</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; EHR: Athena<break/>&#x02022; EHR
modified to: 1) accommodate the USAUDIT and ASSIST-FC scores; 2)
facilitate documentation of BI and referral services (e.g., Smart
Phrases) within the clinical workflow; 3) include automatic referral
processes to local treatment agencies; and 4) add the Connecticut SBI
billing codes to PPSNE&#x02019;s fee schedule<break/>&#x02022; Alcohol SBI
and FASDs competencies training integrated into PPSNE&#x02019;s online
Learning Management System for new staff hires</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; EHR: Epic, Epic
OCHIN<break/>&#x02022; EHR modified to include SmartPhrases, SmartSets,
and added decision support plan for alcohol use disorder medications,
and automated patient education materials<break/>&#x02022; Some trainings
assisted with EHR documentation processes in specific
clinics<break/>&#x02022; Podcast dissemination integrated with
BMC&#x02019;s CME online platform</td><td align="left" valign="bottom" rowspan="1" colspan="1">&#x02022; EHR: HFH IT and CIAS developers
built a secure interface between the eSBI and Epic<break/>&#x02022; For
patients scoring above recommended cutoffs, a BPA alerts provider and
includes brief talking points for initiating a discussion with the
patient and the option to submit a referral to see a behavioral health
specialist</td></tr><tr><td colspan="2" align="center" valign="bottom" rowspan="1">
<bold>Program Evaluation and
Dissemination</bold>
</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Implementation fidelity monitored
monthly via EHR reports and clinician feedback<break/>&#x02022;
Dashboards display screening and BI rates by clinic; dashboards under
development will display clinician-specific rates to support quality
assurance efforts<break/>&#x02022; Data dashboards reviewed monthly by
leadership team, development of internal dashboards for use by clinic
leadership<break/>&#x02022; Presentations of outcomes at conferences;
papers in peer-reviewed journals</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Monthly reports using EHR data
monitor progress at each health center<break/>&#x02022; Feedback includes
screening and BI performance rates and clinician-specific BI
documentation quality provided to PPSNE leadership, regional directors,
health center managers and staff<break/>&#x02022; Presentations of
outcomes at conferences; papers in peer-reviewed journals</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Weekly updates provided at team
meetings<break/>&#x02022; Training outcomes and satisfaction tracked
through surveys (i.e., pre, post, follow-up), polling during trainings,
and reflecting questions between trainings<break/>&#x02022; Training
observations with feedback for quality monitoring<break/>&#x02022;
Quarterly reports using EHR data to monitor progress at each
center<break/>&#x02022; Feedback includes screening and BI performance
rates and clinician-specific BI documentation quality<break/>&#x02022;
Regular use of data (i.e., tracking, process, outcomes) for evaluation,
quality monitoring and improvement, and clinic
recruitment<break/>&#x02022; Multimedia (i.e., training video, podcast,
educational video, website); print (i.e., brochure, infographics
internal reports); presentations and conferences; papers in
peer-reviewed journals</td><td align="left" valign="top" rowspan="1" colspan="1">&#x02022; Piloted in one clinic with a
progressive, stepwise roll out thereafter<break/>&#x02022; Implementation
team provided regular clinic updates, progress reports and monitored
follow through on all aspects of eSBI intervention, including
click-through rates on BPAs triggered by positive screens, screening and
follow through rates on handing out iPads and feedback on impact on
workflows<break/>&#x02022; Conversations and follow up conducted
regularly, as needed, to troubleshoot and correct issues with protocol
fidelity and to identify adjustments to better facilitate uptake of the
intervention. Additionally, the CIAS software and eSBI protocol allowed
for monitoring patient engagement, satisfaction, and preferences with
the intervention. This allowed the intervention team to make adjustments
to improve user experience <break/>&#x02022; Development of a dashboard
by implementation team used with clinic managers and other leadership to
highlight progress and identify opportunities for improved
implementation.<break/>&#x02022; Presentations and papers at conferences,
Grand Rounds, etc.</td></tr></tbody></table><table-wrap-foot><fn id="TFN1"><p id="P54">UAA: University of Alaska Anchorage; PPGNHAIK: Planned Parenthood
Great Northwest, Hawai&#x02019;i, Alaska, Indiana, Kentucky; PPSNE: Planned
Parenthood of Southern New England; BMC: Boston Medical Center; BUSPH:
Boston University School of Public Health; HFH: Henry Ford Health; CHRT:
Center for Health and Research Transformation; SBIRT: screening, brief
intervention, and referral to treatment; USAUDIT-C: Alcohol Use Disorders
Identification Test, US version, items 1&#x02013;3; SISQ: Single Item
Screening Question; NIDA: National Institute on Drug Abuse; USAUDIT: Alcohol
Use Disorders Identification Test, US version; DAST-10: Drug Abuse Screening
Test, 10-item; ASSIST-FC: Alcohol Smoking and Substance Involvement
Screening Test-Frequency and Concern; WHO: World Health Organization;
FRAMES: Feedback, Responsibility, Advice, Menu Options, Empathy,
Self-efficacy; EHR: electronic health record; SUD: substance use disorder;
BPA: best practice alert; PCMH: patient-centered medical home; CHC:
community health centers; SBI: screening and brief intervention; BI: brief
intervention; eSBI: electronic screening and brief intervention; CME:
continuing medical education; FASD or FASDs: fetal alcohol spectrum
disorders; CDC: Centers for Disease Control and Prevention; CIAS:
Computerized Intervention Authoring System; AUD: alcohol use disorder; IT:
information technology</p></fn></table-wrap-foot></table-wrap><table-wrap position="float" id="T3"><label>Table 3.</label><caption><title>Number and Type of Staff Trained in Alcohol SBI Service Delivery by Program
(n=4)</title></caption><table frame="box" rules="all"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th align="center" valign="top" rowspan="1" colspan="1"/><th align="center" valign="top" rowspan="1" colspan="1">UAA/PPGNHAIK</th><th align="center" valign="top" rowspan="1" colspan="1">UConn Health/PPSNE</th><th align="center" valign="top" rowspan="1" colspan="1">BUSPH/Boston HealthNet, BMC</th><th align="center" valign="middle" rowspan="1" colspan="1">CHRT/HFH</th><th align="center" valign="middle" rowspan="1" colspan="1">TOTAL</th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Total Staff Trained</bold>
<sup>
<xref rid="TFN3" ref-type="table-fn">1</xref>
</sup>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>445</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>235</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>516</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>63</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>1,259</bold>
</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Trained by Type of
Staff</bold>
<sup>
<xref rid="TFN4" ref-type="table-fn">2</xref>
</sup>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>438</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>235</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>287</bold>
<sup>
<xref rid="TFN5" ref-type="table-fn">3</xref>
</sup>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>63</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>1,023</bold>
</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Clinicians/Providers</td><td align="center" valign="top" rowspan="1" colspan="1">40</td><td align="center" valign="top" rowspan="1" colspan="1">49</td><td align="center" valign="top" rowspan="1" colspan="1">214</td><td align="center" valign="top" rowspan="1" colspan="1">37</td><td align="center" valign="top" rowspan="1" colspan="1">340</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;&#x02003;Physician</td><td align="center" valign="top" rowspan="1" colspan="1">2</td><td align="center" valign="top" rowspan="1" colspan="1">0</td><td align="center" valign="top" rowspan="1" colspan="1">125</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">127</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;&#x02003;Physician Assistant/Nurse
Practitioner</td><td align="center" valign="top" rowspan="1" colspan="1">33</td><td align="center" valign="top" rowspan="1" colspan="1">40</td><td align="center" valign="top" rowspan="1" colspan="1">70</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">143</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;&#x02003;Certified Nurse Midwife</td><td align="center" valign="top" rowspan="1" colspan="1">5</td><td align="center" valign="top" rowspan="1" colspan="1">9</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">15</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;&#x02003;Other Clinician/Provider
(i.e., Behavioral Health, Social Worker)</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">0</td><td align="center" valign="top" rowspan="1" colspan="1">18</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">18</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Registered Nurse, Medical/Clinic
Assistant</td><td align="center" valign="top" rowspan="1" colspan="1">200</td><td align="center" valign="top" rowspan="1" colspan="1">142</td><td align="center" valign="top" rowspan="1" colspan="1">47</td><td align="center" valign="top" rowspan="1" colspan="1">14</td><td align="center" valign="top" rowspan="1" colspan="1">403</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Other administrative staff (front desk, center
manager, etc.)</td><td align="center" valign="top" rowspan="1" colspan="1">150</td><td align="center" valign="top" rowspan="1" colspan="1">29</td><td align="center" valign="top" rowspan="1" colspan="1">0</td><td align="center" valign="top" rowspan="1" colspan="1">12</td><td align="center" valign="top" rowspan="1" colspan="1">191</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Non-clinical leadership, management,
trainers</td><td align="center" valign="top" rowspan="1" colspan="1">48</td><td align="center" valign="top" rowspan="1" colspan="1">15</td><td align="center" valign="top" rowspan="1" colspan="1">21</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">84</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Other Type</td><td align="center" valign="top" rowspan="1" colspan="1">&#x02013;</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">5</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">5</td></tr></tbody></table><table-wrap-foot><fn id="TFN2"><p id="P55">SBI: screening and brief intervention; UAA: University of Alaska
Anchorage; PPGNHAIK: Planned Parenthood Great Northwest, Hawai&#x02019;i,
Alaska, Indiana, Kentucky; PPSNE: Planned Parenthood of Southern New
England; BMC: Boston Medical Center; BUSPH: Boston University School of
Public Health; HFH: Henry Ford Health; CHRT: Center for Health and Research
Transformation</p></fn><fn id="TFN3"><label>1</label><p id="P56">This number represents the total number of staff/providers trained
in each program, regardless of whether they indicated a staff type. Type of
staff was not collected of all trainees;</p></fn><fn id="TFN4"><label>2</label><p id="P57">This number represents the total number of staff trained in each
program who indicated a specialty type;</p></fn><fn id="TFN5"><label>3</label><p id="P58">This number includes staff trained virtually and for whom specialty
type was collected.</p></fn></table-wrap-foot></table-wrap><table-wrap position="float" id="T4"><label>Table 4.</label><caption><title>Alcohol and Other Drug Use Screening, Brief Intervention and Referral Rates
by Program (7/1/2019&#x02013;6/30/2022)</title></caption><table frame="box" rules="all"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th align="left" valign="middle" rowspan="1" colspan="1"/><th align="center" valign="bottom" rowspan="1" colspan="1">UAA/PPGNHAIK</th><th align="center" valign="bottom" rowspan="1" colspan="1">UConn Health/PPSNE</th><th align="center" valign="top" rowspan="1" colspan="1">BUSPH/Boston HealthNet, BMC</th><th align="center" valign="bottom" rowspan="1" colspan="1">CHRT/HFH<sup><xref rid="TFN7" ref-type="table-fn">1</xref></sup></th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of health centers reporting
data</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>24</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>15</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>6</bold>
<sup>
<xref rid="TFN8" ref-type="table-fn">2</xref>
</sup>
</td><td align="center" valign="top" rowspan="1" colspan="1">
<bold>3</bold>
</td></tr><tr><td colspan="5" align="left" valign="bottom" rowspan="1">
<bold>Screening for Alcohol
Use</bold>
</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients in target
population</bold>
<italic toggle="yes">(# of patients who should have been screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">21,171</td><td align="center" valign="bottom" rowspan="1" colspan="1">15,498</td><td align="center" valign="bottom" rowspan="1" colspan="1">268,651</td><td align="center" valign="bottom" rowspan="1" colspan="1">3,078</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients screened for
alcohol</bold>
<italic toggle="yes">(# of patients who are actually screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">18,949</td><td align="center" valign="bottom" rowspan="1" colspan="1">12,924</td><td align="center" valign="bottom" rowspan="1" colspan="1">74,676</td><td align="center" valign="bottom" rowspan="1" colspan="1">277</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients screened for
alcohol</bold>
<italic toggle="yes">(# of patients screened/# in the target
population)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">89.50%</td><td align="center" valign="bottom" rowspan="1" colspan="1">83.39%</td><td align="center" valign="bottom" rowspan="1" colspan="1">27.80%</td><td align="center" valign="bottom" rowspan="1" colspan="1">9.00%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients who screen positive
for alcohol</bold>
<italic toggle="yes">(# of patients deemed positive for risky alcohol
use)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">2,025</td><td align="center" valign="bottom" rowspan="1" colspan="1">2,189</td><td align="center" valign="bottom" rowspan="1" colspan="1">5,799</td><td align="center" valign="bottom" rowspan="1" colspan="1">74</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for alcohol</bold>
<italic toggle="yes">(# of patients who screen positive/# of patients
screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">10.69%</td><td align="center" valign="bottom" rowspan="1" colspan="1">16.90%</td><td align="center" valign="bottom" rowspan="1" colspan="1">7.77%</td><td align="center" valign="bottom" rowspan="1" colspan="1">26.71%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients who screen positive
for alcohol who receive a brief intervention</bold>
<sup>
<xref rid="TFN9" ref-type="table-fn">3</xref>
</sup>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">729</td><td align="center" valign="bottom" rowspan="1" colspan="1">43</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for alcohol who receive a brief intervention</bold>
<italic toggle="yes">(# of patients who receive a BI/# of patients who screen
positive)</italic><sup><xref rid="TFN9" ref-type="table-fn">3</xref></sup></td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">12.57%</td><td align="center" valign="bottom" rowspan="1" colspan="1">58.11%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients scoring in the
high-risk range/possible moderate to severe AUD</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">49</td><td align="center" valign="bottom" rowspan="1" colspan="1">47</td><td align="center" valign="bottom" rowspan="1" colspan="1">178</td><td align="center" valign="bottom" rowspan="1" colspan="1">47</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients scoring in the
high-risk range/possible moderate to severe AUD</bold>
<italic toggle="yes">(# of patients scoring in the high-risk range/possible moderate
to severe AUD/ # of patients screened for alcohol)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">0.26%</td><td align="center" valign="bottom" rowspan="1" colspan="1">0.36%</td><td align="center" valign="bottom" rowspan="1" colspan="1">0.24%</td><td align="center" valign="bottom" rowspan="1" colspan="1">16.97%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients referred for
additional treatment for alcohol</bold>
<sup>
<xref rid="TFN9" ref-type="table-fn">3</xref>
</sup>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">10</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">1,270</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients referred for
alcohol</bold>
<italic toggle="yes">(# of patients referred for alcohol/# of patients who should
have been referred [scoring in the high-risk range/possible moderate
to severe AUD])</italic><sup><xref rid="TFN9" ref-type="table-fn">3</xref></sup></td><td align="center" valign="bottom" rowspan="1" colspan="1">20.41%</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr><tr><td colspan="5" align="left" valign="bottom" rowspan="1">
<bold>Screening for Drug
Use</bold>
</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients in target
population</bold>
<italic toggle="yes">(# of patients who should have been screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">21,171</td><td align="center" valign="bottom" rowspan="1" colspan="1">15,498</td><td align="center" valign="bottom" rowspan="1" colspan="1">271,655</td><td align="center" valign="bottom" rowspan="1" colspan="1">3,078</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients screened for
drugs</bold>
<italic toggle="yes">(# of patients who are actually screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">17,749</td><td align="center" valign="bottom" rowspan="1" colspan="1">12,970</td><td align="center" valign="bottom" rowspan="1" colspan="1">73,621</td><td align="center" valign="bottom" rowspan="1" colspan="1">252</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients screened for
drugs</bold>
<italic toggle="yes">(# of patients screened/# in the target
population)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">83.84%</td><td align="center" valign="bottom" rowspan="1" colspan="1">83.69%</td><td align="center" valign="bottom" rowspan="1" colspan="1">27.10%</td><td align="center" valign="bottom" rowspan="1" colspan="1">8.19%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Number of patients who screen positive
for any drug</bold>
<italic toggle="yes">(# of patients deemed positive for risky drug use)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">3,484</td><td align="center" valign="bottom" rowspan="1" colspan="1">4,307</td><td align="center" valign="bottom" rowspan="1" colspan="1">2,370</td><td align="center" valign="bottom" rowspan="1" colspan="1">41</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for any drug</bold>
<italic toggle="yes">(# of patients who screen positive/# of patients
screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">19.63%</td><td align="center" valign="bottom" rowspan="1" colspan="1">33.21%</td><td align="center" valign="bottom" rowspan="1" colspan="1">3.22%</td><td align="center" valign="bottom" rowspan="1" colspan="1">16.27%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients scoring in the
high-risk range for any drug</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">62</td><td align="center" valign="bottom" rowspan="1" colspan="1">219</td><td align="center" valign="bottom" rowspan="1" colspan="1">135</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients scoring in the
high-risk range for any drug</bold>
<italic toggle="yes">(# of patients scoring in the high-risk range for drugs/# of
patients screened for drugs)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">0.35%</td><td align="center" valign="bottom" rowspan="1" colspan="1">1.69%</td><td align="center" valign="bottom" rowspan="1" colspan="1">0.18%</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr><tr><td colspan="5" align="left" valign="bottom" rowspan="1">
<bold>Screening for Alcohol
and/or Drug Use</bold>
</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients screened for alcohol
or other drugs (any substance)</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">19,052</td><td align="center" valign="bottom" rowspan="1" colspan="1">13,001</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">252<sup><xref rid="TFN10" ref-type="table-fn">4</xref></sup></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients who screen positive
for any substance</bold>
<sup>
<xref rid="TFN11" ref-type="table-fn">5</xref>
</sup>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">4,825</td><td align="center" valign="bottom" rowspan="1" colspan="1">5,251</td><td align="center" valign="bottom" rowspan="1" colspan="1">6,889</td><td align="center" valign="bottom" rowspan="1" colspan="1">117</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for any substance</bold>
<italic toggle="yes">(# of patients who screen positive/# of patients
screened)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">25.33%</td><td align="center" valign="bottom" rowspan="1" colspan="1">40.39%</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">46.43%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients who screen positive
for any substance who receive a brief intervention</bold>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">2,968</td><td align="center" valign="bottom" rowspan="1" colspan="1">2,830</td><td align="center" valign="bottom" rowspan="1" colspan="1">947</td><td align="center" valign="bottom" rowspan="1" colspan="1">46</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for any substance who receive a brief intervention</bold>
<italic toggle="yes">(# of patients who receive a BI/# of patients who screen
positive)</italic></td><td align="center" valign="bottom" rowspan="1" colspan="1">61.51%</td><td align="center" valign="bottom" rowspan="1" colspan="1">53.89%</td><td align="center" valign="bottom" rowspan="1" colspan="1">13.75%</td><td align="center" valign="bottom" rowspan="1" colspan="1">39.32%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Number of patients who screen positive
for any substance who are referred for additional
treatment</bold>
<sup>
<xref rid="TFN9" ref-type="table-fn">3</xref>
</sup>
</td><td align="center" valign="bottom" rowspan="1" colspan="1">11</td><td align="center" valign="bottom" rowspan="1" colspan="1">160</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"><bold>Percent of patients who screen positive
for any substance who are referred for additional treatment</bold>
<italic toggle="yes">(# of patients who are referred/# who screened</italic>
<bold><italic toggle="yes">positive</italic></bold>)<sup><xref rid="TFN9" ref-type="table-fn">3</xref></sup></td><td align="center" valign="bottom" rowspan="1" colspan="1">0.23%</td><td align="center" valign="bottom" rowspan="1" colspan="1">3.05%</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td><td align="center" valign="bottom" rowspan="1" colspan="1">--</td></tr></tbody></table><table-wrap-foot><fn id="TFN6"><p id="P59">SBI: screening and brief intervention; UAA: University of Alaska
Anchorage; PPGNHAIK: Planned Parenthood Great Northwest, Hawai&#x02019;i,
Alaska, Indiana, Kentucky; PPSNE: Planned Parenthood of Southern New
England; BMC: Boston Medical Center; BUSPH: Boston University School of
Public Health; HFH: Henry Ford Health; CHRT: Center for Health and Research
Transformation; BI: brief intervention; AUD: alcohol use disorder.</p></fn><fn id="TFN7"><label>1</label><p id="P60">Implementation at HFH eSBI began in January 2021 due to IT delays
and COVID-19 related clinic shutdowns. Data presented here is from January
2021-June 2022;</p></fn><fn id="TFN8"><label>2</label><p id="P61">This number reflects the number of health centers that consented to
provide EHR data for this evaluation;</p></fn><fn id="TFN9"><label>3</label><p id="P62">In some cases, it is not possible to distinguish for which substance
(alcohol or other substances) the brief intervention or referral was
conducted;</p></fn><fn id="TFN10"><label>4</label><p id="P63">This number reflects those screened for substances other than
alcohol;</p></fn><fn id="TFN11"><label>5</label><p id="P64">This is applicable when sites are using screeners that capture
multiple substances, not only alcohol. The number includes screen-positives
for any substance so that includes alcohol as well as any other substance
assessed.</p></fn></table-wrap-foot></table-wrap><table-wrap position="float" id="T5"><label>Table 5.</label><caption><title>Demographic Characteristics of Patients Served Across Programs
(7/1/2019&#x02013;6/30/2022)</title></caption><table frame="box" rules="all"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"/><th align="center" valign="middle" rowspan="1" colspan="1">UAA/PPGNHAIK (n=21,173)</th><th align="center" valign="middle" rowspan="1" colspan="1">UConn Health/PPSNE (n=15,498)</th><th align="center" valign="top" rowspan="1" colspan="1">BUSPH/Boston HealthNet, BMC (n=268,651)</th><th align="center" valign="middle" rowspan="1" colspan="1">CHRT/HFH<sup><xref rid="TFN13" ref-type="table-fn">1</xref></sup> (n=4,013)</th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Gender (% female)</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">97.4%</td><td align="center" valign="top" rowspan="1" colspan="1">100.0%</td><td align="center" valign="top" rowspan="1" colspan="1">47.5%</td><td align="center" valign="top" rowspan="1" colspan="1">100.0%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Age [mean (SD)]</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1">29.41 (7.83)</td><td align="center" valign="top" rowspan="1" colspan="1">34.08 (9.95)</td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">30.89 (7.99)</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Race/ethnicity (%)</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Alaska Native/American
Indian</bold></td><td align="center" valign="middle" rowspan="1" colspan="1">1.6%</td><td align="center" valign="middle" rowspan="1" colspan="1">0.4%</td><td align="center" valign="middle" rowspan="1" colspan="1">0.2%</td><td align="center" valign="middle" rowspan="1" colspan="1">0.0%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Asian/Pacific
Islander</bold></td><td align="center" valign="top" rowspan="1" colspan="1">8.2%</td><td align="center" valign="top" rowspan="1" colspan="1">2.6%</td><td align="center" valign="top" rowspan="1" colspan="1">2.8%</td><td align="center" valign="top" rowspan="1" colspan="1">2.0%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Black</bold></td><td align="center" valign="top" rowspan="1" colspan="1">9.5%</td><td align="center" valign="top" rowspan="1" colspan="1">20.4%</td><td align="center" valign="top" rowspan="1" colspan="1">37.1%</td><td align="center" valign="top" rowspan="1" colspan="1">72.0%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>White</bold></td><td align="center" valign="top" rowspan="1" colspan="1">Hispanic: 3.7%<break/>Non-Hispanic:
68.6%</td><td align="center" valign="bottom" rowspan="1" colspan="1">46.1%</td><td align="center" valign="bottom" rowspan="1" colspan="1">24.6%</td><td align="center" valign="bottom" rowspan="1" colspan="1">17.6%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Other/Unknown</bold></td><td align="center" valign="top" rowspan="1" colspan="1">Multi-racial /other: 7.9%; Unknown/prefer
not to answer: 0.7%</td><td align="center" valign="bottom" rowspan="1" colspan="1">5.8%</td><td align="center" valign="bottom" rowspan="1" colspan="1">Other: 13.4%; Unknown: 11.3%</td><td align="center" valign="bottom" rowspan="1" colspan="1">8.4%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Hispanic</bold></td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">24.7%</td><td align="center" valign="top" rowspan="1" colspan="1">10.6%</td><td align="center" valign="top" rowspan="1" colspan="1">5.2%</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">
<bold>Insurance type (%)</bold>
</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1">Not collected</td><td align="center" valign="top" rowspan="1" colspan="1">Not collected</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Public</bold></td><td align="center" valign="top" rowspan="1" colspan="1">42.0%</td><td align="center" valign="top" rowspan="1" colspan="1">42.7%</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Self-pay/uninsured</bold></td><td align="center" valign="top" rowspan="1" colspan="1">--</td><td align="center" valign="top" rowspan="1" colspan="1">15.4%</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">&#x02003;<bold>Commercial</bold></td><td align="center" valign="top" rowspan="1" colspan="1">58.0%</td><td align="center" valign="top" rowspan="1" colspan="1">41.9%</td><td align="center" valign="top" rowspan="1" colspan="1"/><td align="center" valign="top" rowspan="1" colspan="1"/></tr></tbody></table><table-wrap-foot><fn id="TFN12"><p id="P65">SBI: Screening and brief intervention; UAA: University of Alaska
Anchorage; PPGNHAIK: Planned Parenthood Great Northwest, Hawai&#x02019;i,
Alaska, Indiana, Kentucky; PPSNE: Planned Parenthood of Southern New
England; BMC: Boston Medical Center; BUSPH: Boston University School of
Public Health; HFH: Henry Ford Health; CHRT: Center for Health and Research
Transformation.</p></fn><fn id="TFN13"><label>1</label><p id="P66">Time period for demographic data collected at CHRT/HFH is
1/1/21&#x02013;6/30/22.</p></fn></table-wrap-foot></table-wrap></floats-group></article>