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Early report of serious eye infections associated with soft contact lens solution

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  • English
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    Details:

    • Journal Article:
      HAN
    • Corporate Authors:
    • Description:
      Friday, May 25, 2007, 21:39 EDT (09:39 PM EDT)

      CDCHAN-00260-2007-05-25-ADV-N

      The Centers for Disease Control and Prevention (CDC), collaborating with the Food and Drug Administration, state and other partners, has identified an outbreak of a serious but rare eye infection called Acanthamoeba keratitis (AK). This infection is caused by a free-living ameba (Acanthamoeba) a microscopic organism found everywhere in nature. Infections can result in permanent visual impairment or blindness. AK primarily affects otherwise healthy people, most of whom wear contact lenses. In the United States, an estimated 85% of cases of this infection occur in contact lens users. The incidence of the disease in the U.S. is approximately one to two cases per million contact lens users.

      CDC has received reports of 138 cases of culture-confirmed AK in 35 states and Puerto Rico, with complete patient data available for 46 case-patients. Thirty-nine of the 46 case patients wore soft contact lenses. Preliminary information obtained by CDC from patient interviews indicates that, among soft contact lens users who reported the use of any type of solution, 21 (58%) reported having used Advanced Medical Optics (AMO) Complete Moisture Plus™ Multi-Purpose Solution in the month prior to symptom onset. Out of the 37case-patients for whom clinical data was available, 9 (24%) failed medical therapy and required or are expected to undergo corneal transplantation.

    • Subjects:
    • Series:
      HAN ; 260
    • Document Type:
      HAN Health Advisory
    • Place as Subject:
      United States
    • Location:
      North America
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