Validation of a neurobehavioral test system.

Details

• Personal Author:
  Letz R
• Description:
  This study attempted to validate tests from the computerized Neurobehavioral Evaluation System (NES) for use in field investigations where repeated testing of the same subjects is required. Personal samples of styrene (100425) in the breathing zone air and post shift urinary mandelic-acid (90642) were collected for 116 workers in six fiberglass boat building companies located in New England. The average exposure to styrene was 4.6 years with an 8 hour time weighted average styrene exposure of 29.9 parts per million (ppm) and urinary mandelic-acid averaging 490 milligrams/gram creatinine. A statistically significant relationship was found between post shift performance on the Symbol/Digit test and both acute styrene exposure and mandelic-acid concentration. Other analyses comparing workers exposed to less than 50ppm and greater than 50ppm styrene also showed a significant difference in Symbol/Digit performance. All three NES tests showed test/retest correlation coefficients above 0.80, and ease of use for collection of neurobehavioral data under field conditions was demonstrated. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no pdf
• Subjects:
  Glass Nervous System Nervous System Diseases Occupational Health Safety Ships Urine
• Keywords:
  NIOSH-Grant; Neurotoxic-effects; Nervous-system-disorders; Urinalysis; Fiberglass-industry; Boat-manufacturing-industry
• Series:
  Grant Final Reports
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-35
• NIOSHTIC Number:
  nn:00197939
• NTIS Accession Number:
  PB91184572
• Citation:
  Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York 1990 Mar; :1-35
• Contact Point Address:
  Community Medicine Mount Sinai School of Medicine One Gustave L Levy Place New York, N Y 10029
• CAS Registry Number:
  Mandelic acid (CAS RN 90-64-2) ; Styrene (CAS RN 100-42-5)
• Federal Fiscal Year:
  1990
• NORA Priority Area:
  Neurotoxic Disorders ; Neurotoxic Effects
• Performing Organization:
  Mount Sinai School of Medicine, New York, New York
• Peer Reviewed:
  False
• Start Date:
  19861101
• Source Full Name:
  Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York
• End Date:
  19870831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/246217/cdc_246217_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]