American national standard for testing and performance-verification methodologies for ventilation systems for biosafety level 3 (BSL-3) and animal biosafety level 3 (ABSL-3) facilities

Details

• Corporate Authors:
  American National Standards Institute. Z9.14 Subcommittee
• Description:
  The Z9.14 Subcommittee was chartered to develop the American National Standard, Testing and Performance-Verification Methodologies for Ventilation Systems for Biosafety Level 3 (BSL- 3) and Animal Biosafety Level 3 (ABSL-3) Facilities. Over 1,000 BSL-3/ABSL-3 laboratories and animal facilities have been constructed in the United States. The design for their ventilation systems has been largely guided by the criteria defined in successive versions of Biosafety in Microbiological and Biomedical Laboratories (BMBL) from the Department of Health and Human Services (DHHS), the Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH) (Biosafety in Microbiological and Biomedical Laboratories (BMBL) n.d.); the American Society of Heating, Refrigerating and Air Conditioning Engineers (ASHRAE) standards; U.S. Department of Agriculture Animal Research Service (USDA ARS) 242.1 Manual; World Health Organization (WHO) Biosafety Guidelines: Biosafety Manual; and the National Institutes of Health Design Requirements Manual (DRM). Many of these guidelines offer design requirements, but lack the testing and performance-verification methodology to ensure the safe operation of the ventilation system for these laboratories. Using a risk assessment and performance-based approach, this standard provides the technical specifications and background information needed to address the technical, engineering, and associated systems for ventilation within a BSL-3/ABSL-3 laboratory. As such, it is fully compatible with biorisk-management systems and national and international health and safety management systems without duplicating or contradicting their requirements. The purpose of the ventilation system is to provide the necessary environment for biocontainment, occupational health, and animal health in accordance with standards and containment guidelines. It specifically is designed to prevent unintended release of aerosolized infectious biological agents. The ANSI Z9.14 standard provides the combined knowledge acquired over the years by biosafety professionals, design professionals, and owners/operators of BSL-3/ ABSL-3 laboratories, which establishes the requirements and methodologies for the testing and performance verification of the ventilation system. The ANSI Z9.14 standard focuses specifically on the ventilation system features of BSL-3/ ABSL-3 facilities. Because the ventilation system is affected by and has an effect on other systems and equipment in a laboratory, those systems and equipment may be included in the standard, to some extent, as an associated system. ANSI Z9.14 provides testing standardization, uniformity, and consistency through the use of minimal performance-based testing and verification methodologies for BSL-3/ABSL-3 ventilation systems in facilities. [Description provided by NIOSH]
• Subjects:
  Biological Products Environmental Monitoring Hazardous Substances Laboratories Microbiology Occupational Health Quality Control Safety Ventilation Workplace
• Keywords:
  Analytical-methods Biohazards Biological-agents Biological-material Biomedical-engineering Controlled-environment Environmental-control-equipment Equipment-design Equipment-reliability Laboratory-animals Laboratory-workers Microorganisms Performance-capability Quality-standards Safety-engineering Standards Testing-equipment Ventilation-equipment Ventilation-systems Work-environment

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• Publisher:
  American Society of Safety Engineers
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  Illinois ; Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-127
• NIOSHTIC Number:
  nn:20046473
• Citation:
  Des Plaines, IL: American Society of Safety Engineers, ANSI/ASSE Z9.14-2014, 2014 Feb; :1-127
• Contact Point Address:
  Timothy R. Fisher, Secretary, American Society of Safety Engineers, 1800 East Oakton Street, Des Plaines, Illinois 60018·2187
• Email:
  tfisher@asse.org
• Federal Fiscal Year:
  2014
• Peer Reviewed:
  False
• Source Full Name:
  American national standard for testing and performance-verification methodologies for ventilation systems for biosafety level 3 (BSL-3) and animal biosafety level 3 (ABSL-3) facilities
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:094cde48627abe53abdf89e2e2b8cebcbb26bfd2698e0584a84625d7bcdb3b7e490304e9e966dc67bafefc849e6228093955f318f91d16b7ff2bfb88ce5dacfa
• Download URL:
  https://stacks.cdc.gov/view/cdc/201521/cdc_201521_DS1.pdf
• File Type:
  [PDF - 1.85 MB ]