Emerg Infect DisEIDEmerging Infectious Diseases1080-60401080-6059Centers for Disease Control and Prevention272732209-007110.3201/eid1506.090071PerspectiveCME ACTIVITY: Past, Present, and Possible Future Human Infection with Influenza Virus A Subtype H762009156859859Past, Present, and Possible Future Human Infection with Influenza Virus A Subtype H7

Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Medscape, LLC designates this educational activity for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at http://www.medscape.com/cme/eid; (4) view/print certificate.

Learning Objectives

Upon completion of this activity, participants will be able to:

Describe the transmission mechanism and attack rate for the H7 strain of influenza virus in humans

Describe clinical manifestations of H7 virus infection in humans

Identify reasons for increased prevalence of human infection with the H7 virus in future

Describe differences in clinical presentation of infection with H5N1 and H7 viruses

Identify the best strategy for protection against avian virus infection for humans

Editor

Carol Snarey, Copyeditor, Emerging Infectious Diseases. Disclosure: Carol Snarey has disclosed no relevant financial relationships.

CME AUTHOR

Désirée Lie, MD, MSEd, Clinical Professor, Family Medicine, University of California, Orange; Director, Division of Faculty Development, UCI Medical Center, Orange, California. Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships.

AUTHORS

Disclosures: Jessica A. Belser, PhD; Carolyn B. Bridges, MD; Jacqueline M. Katz, PhD; and Terrence M. Tumpey, PhD, have disclosed no relevant financial relationships.

Earning CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions and earn continuing medical education (CME) credit, please go to http://www.medscape.com/cme/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.com. If you are not registered on Medscape.com, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit is acceptable as evidence of participation in CME activities. If you are not licensed in the US and want to obtain an AMA PRA CME credit, please complete the questions online, print the certificate and present it to your national medical association.

Article Title: Past, Present, and Possible Future Human Infection with Influenza Virus A Subtype H7
CME Questions

Which of the following best describes the anticipated attack rate of a pandemic influenza virus on the basis of attack rates in past pandemics?

A. 10% to 15%

B. 25% to 35%

C. 40% to 50%

D. 55% to 65%

Which of the following is least likely to be an early clinical manifestation of H7 influenza virus?

A. Pneumonia

B. Conjunctivitis

C. Coryza

D. Encephalitis

Which of the following is the most likely reason for expectations of future human infection with the H7 avian influenza virus?

A. Increased detection in nonpoultry farm animals

B. Increased frequency of human and poultry infection

C. Increased detection of human infection in the African continent

D. All of the above

Which of the following best describes the difference between infection with H5N1 and H7 subtypes of the avian influenza virus in humans?

A. H5N1 manifests most frequently as neurologic disease

B. H7 most frequently manifests as conjunctival disease

C. H7 manifests only rarely as respiratory disease

D. The 2 infections are indistinguishable clinically

Which of the following strategies is considered the best protection of humans against avian influenza viruses?

A. Antiviral agents

B. Quarantine and slaughter of infected poultry

C. Vaccination of humans

D. Handwashing hygiene measures

Activity Evaluation
1. The activity supported the learning objectives.
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2. The material was organized clearly for learning to occur.
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3. The content learned from this activity will impact my practice.
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4. The activity was presented objectively and free of commercial bias.
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