Learning Objectives

Emerg Infect Dis

EID

Emerging Infectious Diseases

1080-60401080-6059

Centers for Disease Control and Prevention

2600400

07-0616

10.3201/eid1408.070616

Research

CME ACTIVITY: Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

82008

14812241224

Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide CME for physicians. Medscape, LLC designates this educational activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at http://www.medscape.com/cme/eid; (4) view/print certificate.

Learning Objectives

Upon completion of this activity, participants will be able to:

Describe the frequency of norovirus (NoV) infection worldwide.

Describe the prevalence of NoV infection among mild-to-moderate community-acquired diarrhea cases.

Describe the morbidity associated with severe diarrhea due to NoV infection.

Identify the most common virulent strains of NoV.

Describe the morbidity and mortality attributed to NoV infection worldwide.

Editor

Anne Mather, Technical Writer-Editor, Emerging Infectious Diseases. Disclosure: Anne Mather has disclosed no relevant financial relationships.

CME AUTHOR

Désirée Lie, MD, MSEd, Clinical Professor, Family Medicine, University of California, Orange; Director, Division of Faculty Development, UCI Medical Center, Orange, California. Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships.

AUTHORS

Disclosures: Manish M. Patel, MD; Marc-Alain Widdowson, VetMB, MSc; Roger I. Glass, MD, PhD; Kenichiro Akazawa; Jan Vinjé, PhD; and Umesh D. Parashar, MBBS, MPH, have disclosed no relevant financial relationships.

Earning CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions and earn continuing medical education (CME) credit, please go to http://www.medscape.com/cme/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.com. If you are not registered on Medscape.com, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit is acceptable as evidence of participation in CME activities. If you are not licensed in the US and want to obtain an AMA PRA CME credit, please complete the questions online, print the certificate and present it to your national medical association.

Article Title: Systematic Literature Review of Role of Noroviruses in Sporadic GastroenteritisCME Questions

Norovirus (NoV) has been documented to cause what percentage of all-cause epidemic gastroenteritis worldwide?

A. 30%

B. 50%

C. 75%

D. 90%

Among 13 studies of community- or clinic-based mild-to-moderate diarrhea cases, what was the most likely pooled proportion attributed to NoV infection?

A. 5%

B. 12%

C. 40%

D. 65%

For severe diarrhea seen in emergency departments and/or resulting in hospitalizations, which of the following best describes the pooled proportion of cases attributable to NoV infection as reported in 23 studies?

A. 2%

B. 11%

C. 23%

D. 35%

Which of the following is considered the most common strain of NoV causing diarrhea among NoV cases?

A. GII.4 cluster

B. GII.1 cluster

C. GI.1 cluster

D. GIII.2 cluster

The worldwide morbidity and mortality from NoV among children in developing countries is best described by which of the following estimations?

A. 5 million hospitalizations

B. 400,000 deaths

C. 216,000 deaths

D. 2.5 million hospitalizations

Activity Evaluation

1. The activity supported the learning objectives.
Strongly Disagree				Strongly Agree
1	2	3	4	5
2. The material was organized clearly for learning to occur.
Strongly Disagree				Strongly Agree
1	2	3	4	5
3. The content learned from this activity will impact my practice.
Strongly Disagree				Strongly Agree
1	2	3	4	5
4. The activity was presented objectively and free of commercial bias.
Strongly Disagree				Strongly Agree
1	2	3	4	5