Emerg Infect DiseidEmerging Infectious Diseases1080-60401080-6059Centers for Disease Control96212072640134Research ArticleClostridium septicum infection and hemolytic uremic syndrome.BarnhamM.WeightmanN.Harrogate General Hospital, United Kingdom.Apr-Jun199842321324

Five cases of Clostridium septicum infection secondary to Escherichia coli O157-induced hemolytic uremic syndrome have been reported. We report on three cases (one of which is included in the above five) of dual Cl. septicum and E. coil infection; all three patients were exposed to farm animals. A common zoonotic source for Cl. septicum and E. coli O157 infections should be considered. Patients with hemolytic uremic syndrome should be treated aggressively and monitored closely for Cl. septicum superinfection.