<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD with MathML3 v1.3 20210610//EN" "JATS-archivearticle1-3-mathml3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.3" xml:lang="en" article-type="research-article"><?properties manuscript?><processing-meta base-tagset="archiving" mathml-version="3.0" table-model="xhtml" tagset-family="jats"><restricted-by>pmc</restricted-by></processing-meta><front><journal-meta><journal-id journal-id-type="nlm-journal-id">9815751</journal-id><journal-id journal-id-type="pubmed-jr-id">21797</journal-id><journal-id journal-id-type="nlm-ta">Nicotine Tob Res</journal-id><journal-id journal-id-type="iso-abbrev">Nicotine Tob Res</journal-id><journal-title-group><journal-title>Nicotine &#x00026; tobacco research : official journal of the Society for Research on Nicotine and Tobacco</journal-title></journal-title-group><issn pub-type="ppub">1462-2203</issn><issn pub-type="epub">1469-994X</issn></journal-meta><article-meta><article-id pub-id-type="pmid">34792585</article-id><article-id pub-id-type="pmc">11000140</article-id><article-id pub-id-type="doi">10.1093/ntr/ntab238</article-id><article-id pub-id-type="manuscript">HHSPA1979079</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Trends in Cigar Sales and Prices, by Product and Flavor Type&#x02014;the United States, 2016&#x02013;2020</article-title></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0002-8346-3339</contrib-id><name><surname>Wang</surname><given-names>Xu</given-names></name><degrees>PhD</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Kim</surname><given-names>Yoonsang</given-names></name><degrees>PhD</degrees><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Borowiecki</surname><given-names>Mateusz</given-names></name><degrees>BA</degrees><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Tynan</surname><given-names>Michael A.</given-names></name><degrees>BA</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Emery</surname><given-names>Sherry</given-names></name><degrees>PhD</degrees><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>King</surname><given-names>Brian A.</given-names></name><degrees>PhD</degrees><xref rid="A1" ref-type="aff">1</xref></contrib></contrib-group><aff id="A1"><label>1</label>Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff><aff id="A2"><label>2</label>NORC at the University of Chicago, Chicago, IL, USA</aff><author-notes><corresp id="CR1">Corresponding Author: Xu Wang, PhD, Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, S107-7, Atlanta, GA 30341, USA. Fax: 770-488-5848; <email>wry3@cdc.gov</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>29</day><month>3</month><year>2024</year></pub-date><pub-date pub-type="ppub"><day>01</day><month>3</month><year>2022</year></pub-date><pub-date pub-type="pmc-release"><day>08</day><month>4</month><year>2024</year></pub-date><volume>24</volume><issue>4</issue><fpage>606</fpage><lpage>611</lpage><permissions><license><license-p>This work is written by (a) US Government employee(s) and is in the public domain in the US.</license-p></license></permissions><abstract id="ABS1"><sec id="S1"><title>Introduction:</title><p id="P1">Cigar smoking has increased in recent decades as the cigar product landscape has diversified. This study assessed trends in US cigar sales during 2016&#x02013;2020.</p></sec><sec id="S2"><title>Aims and Methods:</title><p id="P2">Unit sales and average unit price for cigars were assessed during January 3, 2016&#x02013;June 13, 2020, overall and by product and flavor type, for the 48 contiguous US states and D.C. Assessed cigar types were large cigars, little cigars, and cigarillos; assessed flavor types were tobacco/unflavored, candy/sweets, fruit, menthol, alcohol, coffee, other flavors, and no flavor stated. A joinpoint regression model was used to assess the magnitude and significance of sales trends.</p></sec><sec id="S3"><title>Results:</title><p id="P3">During January 3, 2016&#x02013;June 13, 2020, unit sales of cigarillos increased (average monthly percentage change [AMPC] = 0.7%, <italic toggle="yes">p</italic> &#x0003c; .001), while unit sales of large cigars (AMPC = &#x02212;0.8%, <italic toggle="yes">p</italic> &#x0003c; .001) and little cigars decreased (AMPC = &#x02212;0.2%, <italic toggle="yes">p</italic> &#x0003c; .001). The average price of cigarillos gradually decreased since mid-August 2017 (AMPC = &#x02212;0.1%, <italic toggle="yes">p</italic> &#x0003c; .001), and the average price of little cigars decreased from mid-June 2016 to mid-June 2019 (AMPC = &#x02212;0.3%, <italic toggle="yes">p</italic> &#x0003c; .001). In contrast, the average price of large cigars increased during the entire study period (AMPC = 0.6%, <italic toggle="yes">p</italic> &#x0003c; .001). Irrespective of cigar type, tobacco-flavored/unflavored products were the most commonly sold cigars during the assessed period; however, sales of other flavors varied by cigar type.</p></sec><sec id="S4"><title>Conclusions:</title><p id="P4">Cigar sales and price vary by type over time in the United States, including sales of cigarillos (94.2% of unit sales) increasing as their prices have decreased in recent years. Public health strategies are warranted to address the full scope of cigar types being used in the United States.</p></sec><sec id="S5"><title>Implications:</title><p id="P5">Surveillance of cigar sales data, including product characteristics, can provide a timely complement to self-reported survey data of cigar use. This study assessed trends in US cigar sales during 2016&#x02013;2020, including by product and flavor type. The findings indicate that sales of cigarillos, which comprise most cigar sales in the United States during the assessed period, increased as their prices decreased. Sales of certain flavors, such as candy/sweet cigarillos and coffee large cigars, increased significantly. These findings reinforce the importance of evidence-based strategies, including increasing price and restricting flavors, to reduce the affordability and consumption of cigars in the United States.</p></sec></abstract></article-meta></front><body><sec id="S6"><title>Introduction</title><p id="P6">The US Surgeon General has concluded that combustible tobacco products, such as cigarettes and cigars, are responsible for the overwhelming burden of death and disease from tobacco products.<sup><xref rid="R1" ref-type="bibr">1</xref></sup> Cigar smoking is associated with several of the same health risks as cigarette smoking, such as heart disease, lung cancer, and all-cause mortality.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R2" ref-type="bibr">2</xref></sup> The broad category of cigars includes large cigars, little cigars, and cigarillos. Large cigars include premium hand-rolled cigars and machine-made large cigars. Little cigars are the same size and shape as cigarettes and often include a filter. Cigarillos are typically unfiltered, comparable in size to little cigars.</p><p id="P7">Although cigarette consumption in the United States continues to decline, demand for cigars has increased in recent decades.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R3" ref-type="bibr">3</xref></sup> From 2002 to 2012, per capita sales of cigars increased from 30.5 cigars to 57.4.<sup><xref rid="R3" ref-type="bibr">3</xref></sup> Moreover, self-reported survey data indicate that in 2019, 3.6% (8.7 million) of US adults currently smoked cigars, making it the second most commonly used combustible tobacco product among adults behind cigarettes.<sup><xref rid="R4" ref-type="bibr">4</xref></sup> During the same year, 5.3% (1.4 million) of US middle and high school students currently used cigars, making it the second most commonly used tobacco product among US middle and high school students after e-cigarettes.<sup><xref rid="R5" ref-type="bibr">5</xref></sup></p><p id="P8">Self-reported survey data also indicate that the use of certain cigar types is particularly prominent among young people, including little cigars.<sup><xref rid="R6" ref-type="bibr">6</xref></sup> The use of little cigars among young people is partly driven by the availability of these products in flavors that are otherwise prohibited in conventional cigarettes.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R7" ref-type="bibr">7</xref></sup> Other factors potentially increasing their appeal to consumers, particularly youth, include availability in single-unit quantities and lower prices compared to cigarettes.<sup><xref rid="R8" ref-type="bibr">8</xref></sup> Some cigarette products have been modified by manufacturers by wrapping them in brown paper and increasing their weight, which classifies the products as cigars for tax purposes, thereby reducing their price relative to cigarettes.<sup><xref rid="R9" ref-type="bibr">9</xref></sup> In addition, some or all of the loose tobacco in cigars can be emptied out and replaced with marijuana while retaining the tobacco leaf wrap, which is often called a &#x0201c;blunt.&#x0201d;<sup><xref rid="R10" ref-type="bibr">10</xref></sup></p><p id="P9">Retail sales data can be a timely complement to self-reported surveys, which are frequently conducted once annually and might not fully capture emergent trends. To date, some studies have assessed trends in cigar sales<sup><xref rid="R11" ref-type="bibr">11</xref>-<xref rid="R13" ref-type="bibr">13</xref></sup>; however, little is known about more recent trends in cigar sales volume and price, particularly by product and flavor type. This study used Nielsen data to assess US trends in cigar sales during 2016&#x02013;2020, overall and by product and flavor type. Given the different types of cigars available in the United States, as well as the emergence of policies to prohibit the sale of flavored tobacco products such as little cigars,<sup><xref rid="R14" ref-type="bibr">14</xref></sup> retail sales data could provide timely subannual data to inform public health policy and practice.</p></sec><sec id="S7"><title>Methods</title><sec id="S8"><title>Data Source</title><p id="P10">Retail sales data in 4-week aggregates were obtained from The Nielsen Company (Nielsen) for January 3, 2016&#x02013;June 13, 2020. Data were included for 48 US states and the District of Columbia; data from Hawaii and Alaska were not available. These data included product-specific characteristics associated with each Universal Product Code (UPC), as well as dol-lar sales and unit sales for each UPC. These data are reflective of sales in convenience stores, food/grocery stores, pharmacies, mass merchandisers, club stores, discount/dollar stores, and US military commissaries. Sales through the Internet or tobacco specialty stores are not included.</p></sec><sec id="S9"><title>Measures</title><p id="P11">Cigar products were categorized into three product types (large cigars, little cigars, or cigarillos) based on the description, size (eg, giant, queen, large, mini), presence of tip or filter, and extensive online search on brand-specific information.<sup><xref rid="R12" ref-type="bibr">12</xref></sup> A small fraction of cigar products (0.3% of total dollar sales) could not be categorized because of insufficient information, and were excluded from the analyses.</p><p id="P12">Cigar products were categorized into eight exclusive flavor categories based on the flavor description in the dataset: tobacco/unflavored, candy/sweets, fruit, menthol, alcohol, coffee, other flavors, and not stated. The tobacco/unflavored category included tobacco-flavored products and unflavored products. The &#x0201c;other flavors&#x0201d; category included mint, cannabis, clove, and concept flavors such as &#x0201c;purple wave&#x0201d; and &#x0201c;midnight hour.&#x0201d; Products without flavor description were categorized as &#x0201c;not stated.&#x0201d;</p></sec><sec id="S10"><title>Analysis</title><p id="P13">Both unit and dollar sales were assessed. To aggregate unit sales, units were standardized following the approach by Wang et al<sup><xref rid="R13" ref-type="bibr">13</xref></sup>: one unit was equal to one large cigar, one pack of 20 little cigars, or one pack of 2 cigarillos. Average price per unit was calculated as total dollar sales divided by total standardized units. Unit sale share was calculated as unit sales of a specific category (eg, product type or flavor), divided by total unit sales.</p><p id="P14">Trends in unit sales and average unit price were assessed overall and by product and flavor type across 4-week periods (referred to as &#x0201c;month&#x0201d; henceforth). Joinpoint regression models,<sup><xref rid="R15" ref-type="bibr">15</xref></sup> accounting for autocorrelated errors, were used to detect points in time where the sales direction changed and to quantify the relative amount of change. Average monthly percentage change (AMPC) and corresponding 95% confidence intervals were estimated for the segments of changes and overall changes. For all analyses, <italic toggle="yes">p</italic> &#x0003c; .05 was used to determine statistical significance. Analyses were performed using R version 4.0.2, Joinpoint Regression Program version 4.8.0.0, and Microsoft Excel.</p></sec></sec><sec id="S11"><title>Results</title><p id="P15">During January 2016&#x02013;June 2020, monthly cigarillo unit sales increased from about 131 million to 190 million by an average of 0.7% per month (<italic toggle="yes">p</italic> &#x0003c; .001) during the entire study period (<xref rid="F1" ref-type="fig">Figure 1</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 1</xref>). For large cigars, unit sales decreased during the study period (AMPC = &#x02212;0.8%, <italic toggle="yes">p</italic> &#x0003c; .001). For little cigars, unit sales decreased (AMPC = &#x02212;0.2%, <italic toggle="yes">p</italic> &#x0003c; .001) during the entire study period; however, sales increased during January 2016&#x02013;mid-August 2016 (AMPC = 1.6%, <italic toggle="yes">p</italic> = .01), but decreased since then (AMPC = &#x02212;0.5%, <italic toggle="yes">p</italic> &#x0003c; .001).</p><p id="P16">During January 2016&#x02013;June 2020, the average cigarillo price for a pack of 2 have remained unchanged ($1.31; AMPC = 0.0%, <italic toggle="yes">p</italic> = .8) for the entire study period (<xref rid="F2" ref-type="fig">Figure 2</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 1</xref>). For large cigars, the average price for one increased from $1.44 to $2.06 during the study period (AMPC = 0.6%, <italic toggle="yes">p</italic> &#x0003c; .001). For little cigars, the average price for a pack of 20 was unchanged ($2.94) during the entire study period (AMPC = 0.0%, <italic toggle="yes">p</italic> = .6); however, it decreased during mid-June 2016&#x02013;June 2019 (AMPC = &#x02212;0.3%, <italic toggle="yes">p</italic> &#x0003c; .001).</p><p id="P17">During the study period, total unit sales and unit sale share were greatest for cigarillos (9 688 537 764, 94.2% of unit sales), followed by little cigars (318 202 059, 3.1% of unit sales), and large cigars (274 519 531, 2.7% of unit sales; <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>). Tobacco-flavored/unflavored products were the most common for all three product types assessed; annual unit sale share of tobacco-flavored/unflavored prod-ucts was 83%&#x02212;87% for large cigars, 51%&#x02212;54% for little cigars, and 49%&#x02212;52% for cigarillos during January 2016&#x02013;June 2020. For cigarillos, fruit flavor had the second greatest unit sale share, followed by candy/sweet flavors. Unit sales of tobacco-flavored/unflavored cigarillos increased by an average 0.9% per month overall <italic toggle="yes">(p &#x0003c;</italic> .001); unit sales of candy/ sweet- (AMPC = 1.0%, <italic toggle="yes">p</italic> &#x0003c; .001) and other- (AMPC = 2.5%, <italic toggle="yes">p</italic> &#x0003c; .001) flavored products also increased. For large cigars, candy/sweet and alcohol-flavored products were most popular after tobacco-flavored/unflavored products. Unit sales of tobacco-flavored/unflavored large cigars decreased overall (AMPC = &#x02212;1.0%, <italic toggle="yes">p</italic> &#x0003c; .001); unit sales of candy/sweet- (AMPC = 0.8%, <italic toggle="yes">p</italic> &#x0003c; .001) and coffee- (AMPC = 9.8%, <italic toggle="yes">p</italic> &#x0003c; .001) flavored products increased, while the unit sales of fruit-flavored products decreased (AMPC = &#x02212;4.4%, <italic toggle="yes">p</italic> &#x0003c; .001). For little cigars, menthol had the second highest proportion of overall sales, followed by fruit and candy/sweet flavors. Unit sales of tobacco-flavored/unflavored little cigars decreased overall (AMPC = &#x02212;0.3%, <italic toggle="yes">p</italic> &#x0003c; .001); unit sales of alcohol-flavored products also decreased (AMPC = &#x02212;6.6%, <italic toggle="yes">p</italic> &#x0003c; .001).</p></sec><sec id="S12"><title>Discussion</title><p id="P18">During January 2016&#x02013;June 2020, unit sales of cigars increased in the United States. This increase was driven by steady growth in cigarillo sales during the assessed period, despite decreases in sales of large cigars and little cigars. Moreover, cigarillos were the most commonly sold cigar product, comprising 94.2% of overall sales, followed by little cigars (3.1%) and large cigars (2.7%). During August 2017&#x02013;June 2020, the average price of cigarillos decreased. These findings re-inforce the importance of evidence-based strategies, including increasing price, to reduce the affordability and consumption of the full scope of cigar types being used in the United States, particularly among youth.</p><p id="P19">The current study found that decreases in unit sales of large cigars were accompanied by increases in the price of large cigars; in contrast, the price of cigarillos and little cigars re-mained unchanged during the full study period. When comparing to other higher priced products such as cigarettes, the relatively low cost of cigar products can be an appealing al-ternative to cigarettes, especially among youth.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R16" ref-type="bibr">16</xref></sup> Increasing price is the single most effective strategy for reducing cigarette consumption through both reducing initiation and increased cessation.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R17" ref-type="bibr">17</xref></sup> Similarly, studies have shown that increases in the price of cigars can effectively reduce cigar usage.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R18" ref-type="bibr">18</xref></sup> For example, Jawad et al estimated that a 10% price increase of cigars reduces cigar demand by 8%.<sup><xref rid="R18" ref-type="bibr">18</xref></sup> Therefore, pricing is an important public health strategy for reducing cigar consumption, including preventing not only youth use but also potential tobacco product substitution.</p><p id="P20">The majority of cigar products sold during the assessed period were tobacco-flavored/unflavored products (annual market share of 50%&#x02212;80%) and fruit was the second most commonly sold flavor for cigarillos and menthol was the second most commonly sold flavor for little cigars. Addressing flavored tobacco product sales, particularly candy/sweet flavored cigarillos is important for public health because flavors can mask the harshness of tobacco, making them more appealing to youth and young adults.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R7" ref-type="bibr">7</xref></sup> States and communities have adopted population-wide strategies to prevent youth use of flavored tobacco products, including policies that are specific to cigars. In 2009, New York City prohibited the sale of flavored cigars and smokeless tobacco products, though that policy excluded mint, menthol, and wintergreen and allowed flavored sales to continue in certain adult-only tobacco retailers.<sup><xref rid="R7" ref-type="bibr">7</xref></sup> Similarly, Maine adopted a law in 2009 that prohibited the sale of flavored cigars, exempting premium cigars.<sup><xref rid="R19" ref-type="bibr">19</xref></sup> An analysis of New York&#x02019;s flavor policy found that cigar sales declined by 7.4%, compared with a 12% national increase.<sup><xref rid="R20" ref-type="bibr">20</xref></sup> Similar policies later were adopted by jurisdictions in California, Minnesota, and Rhode Island.<sup><xref rid="R7" ref-type="bibr">7</xref></sup> In 2020, five states (California, Massachusetts, New Jersey, New York, and Rhode Island) adopted statewide laws that prohibited the sale of all flavored tobacco prod-ucts, including menthol.<sup><xref rid="R14" ref-type="bibr">14</xref></sup> In April 2021, the US Food and Drug Administration announced that it plans to issue product standards to ban all characterizing flavors, including menthol, in cigars. The increased sales of cigars documented in this study, coupled with the high proportion of sales that were for flavored products, reinforce the importance of such standards for preventing and reducing cigar use in the United States.</p><sec id="S13"><title>Limitations</title><p id="P21">This study is subject to at least three limitations. First, sales from Hawaii and Alaska, as well as those from the Internet and tobacco specialty shops were not included; therefore, unit sales reported in this study underestimate the total sales volume in the United States. Second, the study could not assess purchaser age; the assessed sales could reflect products purchased by adults or those obtained directly or indirectly by youths. Third, cigar products were categorized into these three product types based on product description in the data and online searches, which might be subject to misclassifica- tion; however, this only applied to 0.3% of total dollar sales. Finally, this study could not account for various factors that might have also impacted patterns of sales, including other tobacco product use (eg, e-cigarettes), tobacco control policies (eg, federal flavor prohibitions), and public health emergencies (eg, COVID-19 and EVALI [e-cigarette, or vaping, product use-associated lung injury]).</p></sec></sec><sec id="S14"><title>Conclusions</title><p id="P22">Cigarillos were the most commonly sold cigar product, with sales increasing steadily as prices remained generally un-changed with slight decreases in recent years. Sales of certain flavors increased depending on cigar type. Comprehensive strategies that address the full scope of cigar products and flavors are warranted to prevent and reduce cigar use in the United States, especially among youth and young adults. These include longstanding strategies, such as increasing price,<sup><xref rid="R1" ref-type="bibr">1</xref></sup> and emerging strategies such as the restriction on flavor sales. Further surveillance of cigar demand, including through more rapidly collected mechanisms such as retail sales, is important to inform the development, implementation, and sustainment of efforts to address cigar use at the national, state, and local levels.</p></sec><sec sec-type="supplementary-material" id="SM1"><title>Supplementary Material</title><supplementary-material id="SD1" position="float" content-type="local-data"><label>Contributorship Form</label><media xlink:href="NIHMS1979079-supplement-Contributorship_Form.pdf" id="d66e421" position="anchor"/></supplementary-material><supplementary-material id="SD2" position="float" content-type="local-data"><label>2</label><media xlink:href="NIHMS1979079-supplement-2.pdf" id="d66e424" position="anchor"/></supplementary-material></sec></body><back><ack id="S16"><title>Funding</title><p id="P24">This work was funded by the US Centers for Disease Control and Prevention (CDC).</p></ack><fn-group><fn id="FN1"><p id="P25">Supplementary Material</p><p id="P26">A Contributorship Form detailing each author&#x02019;s specific involvement with this content, as well as any supplementary data, are available online at <ext-link xlink:href="https://academic.oup.com/ntr" ext-link-type="uri">https://academic.oup.com/ntr</ext-link>.</p></fn><fn id="FN2"><p id="P27">Disclaimer</p><p id="P28">The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the US Centers for Disease Control and Prevention. CDC&#x02019;s analyses and calculations are based in part on data reported by Nielsen through its Scantrack Service for the 4-week period ending June 13, 2020, for the Total US All Outlet Combined + Convenience markets. The conclusions drawn from the Nielsen data are those of the authors and do not reflect the views of Nielsen. Nielsen is not responsible for and had no role in and was not involved in analyzing and preparing the results reported herein. Use of Nielson data does not imply an endorsement of any particular organization, service, or product.</p></fn><fn fn-type="COI-statement" id="FN3"><p id="P29">Declaration of Interests</p><p id="P30"><italic toggle="yes">None</italic> declared.</p></fn></fn-group><sec sec-type="data-availability" id="S15"><title>Data Availability</title><p id="P23">The data underlying this article were provided by The Nielsen Company (Nielsen) under license/by permission. Data will be shared on request to the corresponding author with permission of Nielsen.</p></sec><ref-list><title>References</title><ref id="R1"><label>1.</label><mixed-citation publication-type="book"><collab>US Department of Health and Human Services (USDHHS)</collab>. <source>The Health Consequences of Smoking&#x02014;50 Years of Progress: A Report of the Surgeon General</source>. <publisher-loc>Atlanta, GA</publisher-loc>: <publisher-name>US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health</publisher-name>; <year>2014</year>.</mixed-citation></ref><ref id="R2"><label>2.</label><mixed-citation publication-type="journal"><name><surname>Chang</surname><given-names>CM</given-names></name>, <name><surname>Corey</surname><given-names>CG</given-names></name>, <name><surname>Rostron</surname><given-names>BL</given-names></name>, <name><surname>Apelberg</surname><given-names>BJ</given-names></name>. <article-title>Systematic review of cigar smoking and all cause and smoking related mortality</article-title>. <source>BMC Public Health</source>. <year>2015</year>;<volume>15</volume>(<issue>1</issue>):<fpage>390</fpage>.<pub-id pub-id-type="pmid">25907101</pub-id>
</mixed-citation></ref><ref id="R3"><label>3.</label><mixed-citation publication-type="journal"><name><surname>Agaku</surname><given-names>IT</given-names></name>, <name><surname>Alpert</surname><given-names>HR</given-names></name>. <article-title>Trends in annual sales and current use of cigarettes, cigars, roll-your-own tobacco, pipes, and smokeless tobacco among US adults, 2002&#x02013;2012</article-title>. <source>Tob Control</source>. <year>2016</year>;<volume>25</volume>(<issue>4</issue>):<fpage>451</fpage>&#x02013;<lpage>457</lpage>.<pub-id pub-id-type="pmid">25899447</pub-id>
</mixed-citation></ref><ref id="R4"><label>4.</label><mixed-citation publication-type="journal"><name><surname>Cornelius</surname><given-names>ME</given-names></name>, <name><surname>Wang</surname><given-names>TW</given-names></name>, <name><surname>Jamal</surname><given-names>A</given-names></name>, <name><surname>Loretan</surname><given-names>CG</given-names></name>, <name><surname>Neff</surname><given-names>LJ</given-names></name>. <article-title>Tobacco product use among adults&#x02014;United States, 2019</article-title>. <source>MMWR <italic toggle="yes">Morb Mortal Wkly Rep</italic></source>. <year>2020</year>;<volume>69</volume>(<issue>46</issue>):<fpage>1736</fpage>&#x02013;<lpage>1742</lpage>.<pub-id pub-id-type="pmid">33211681</pub-id>
</mixed-citation></ref><ref id="R5"><label>5.</label><mixed-citation publication-type="journal"><name><surname>Wang</surname><given-names>TW</given-names></name>, <name><surname>Gentzke</surname><given-names>AS</given-names></name>, <name><surname>Creamer</surname><given-names>MR</given-names></name>, <etal/>
<article-title>Tobacco product use and associated factors among middle and high school students&#x02014;United States, 2019</article-title>. <source>MMWR Surveill Summ</source>. <year>2019</year>;<volume>68</volume>(<issue>12</issue>):<fpage>1</fpage>&#x02013;<lpage>22</lpage>.</mixed-citation></ref><ref id="R6"><label>6.</label><mixed-citation publication-type="journal"><name><surname>King</surname><given-names>BA</given-names></name>, <name><surname>Tynan</surname><given-names>MA</given-names></name>, <name><surname>Dube</surname><given-names>SR</given-names></name>, <name><surname>Arrazola</surname><given-names>R</given-names></name>. <article-title>Flavored-little-cigar and flavored-cigarette use among U.S. middle and high school students</article-title>. <source>J Adolesc Health</source>. <year>2014</year>;<volume>54</volume>(<issue>1</issue>):<fpage>40</fpage>&#x02013;<lpage>46</lpage>.<pub-id pub-id-type="pmid">24161587</pub-id>
</mixed-citation></ref><ref id="R7"><label>7.</label><mixed-citation publication-type="journal"><name><surname>Cullen</surname><given-names>KA</given-names></name>, <name><surname>Liu</surname><given-names>ST</given-names></name>, <name><surname>Bernat</surname><given-names>JK</given-names></name>, <etal/>
<article-title>Flavored Tobacco Product Use Among Middle and High School Students&#x02014;United States, 2014&#x02013;2018</article-title>. <source>MMWR Morb Mortal Wkly Rep</source>. <year>2019</year>;<volume>68</volume>(<issue>39</issue>):<fpage>839</fpage>&#x02013;<lpage>844</lpage>.<pub-id pub-id-type="pmid">31581163</pub-id>
</mixed-citation></ref><ref id="R8"><label>8.</label><mixed-citation publication-type="journal"><name><surname>Delnevo</surname><given-names>CD</given-names></name>, <name><surname>Hrywna</surname><given-names>M</given-names></name>. <article-title>&#x0201c;A whole &#x02018;nother smoke&#x0201d; or a cigarette in disguise: how RJ Reynolds reframed the image of little cigars</article-title>. <source>Am J Public Health</source>. <year>2007</year>;<volume>97</volume>(<issue>8</issue>):<fpage>1368</fpage>&#x02013;<lpage>1375</lpage>.<pub-id pub-id-type="pmid">17600253</pub-id>
</mixed-citation></ref><ref id="R9"><label>9.</label><mixed-citation publication-type="book"><collab>Government Accountability Office</collab>. <source>Tobacco Taxes: Large Disparities in Rates for Smoking Products Trigger Significant Market Shifts to Avoid Higher Taxes</source>. <publisher-loc>Washington, DC</publisher-loc>: <publisher-name>Govern-ment Accountability Office</publisher-name>; <year>2012</year>.</mixed-citation></ref><ref id="R10"><label>10.</label><mixed-citation publication-type="journal"><name><surname>Giovenco</surname><given-names>DP</given-names></name>, <name><surname>Miller Lo</surname><given-names>EJ</given-names></name>, <name><surname>Lewis</surname><given-names>MJ</given-names></name>, <name><surname>Delnevo</surname><given-names>CD</given-names></name>. <article-title>&#x0201c;They&#x02019;re pretty much made for blunts&#x0201d;: product features that facilitate marijuana use among young adult cigarillo users in the United States</article-title>. <source>Nicotine Tob Res</source>. <year>2017</year>;<volume>19</volume>(<issue>11</issue>):<fpage>1359</fpage>&#x02013;<lpage>1364</lpage>.<pub-id pub-id-type="pmid">27613943</pub-id>
</mixed-citation></ref><ref id="R11"><label>11.</label><mixed-citation publication-type="journal"><name><surname>Delnevo</surname><given-names>CD</given-names></name>, <name><surname>Giovenco</surname><given-names>DP</given-names></name>, <name><surname>Miller Lo</surname><given-names>EJ</given-names></name>. <article-title>Changes in the mass-merchandise cigar market since the Tobacco Control Act</article-title>. <source>Tob Regul Sci</source>. <year>2017</year>;<volume>3</volume>(<issue>2 Suppl 1</issue>):<fpage>S8</fpage>&#x02013;<lpage>S16</lpage>.<pub-id pub-id-type="pmid">28317004</pub-id>
</mixed-citation></ref><ref id="R12"><label>12.</label><mixed-citation publication-type="journal"><name><surname>Kuiper</surname><given-names>NM</given-names></name>, <name><surname>Gammon</surname><given-names>D</given-names></name>, <name><surname>Loomis</surname><given-names>B</given-names></name>, <etal/>
<article-title>Trends in sales of flavored and menthol tobacco products in the United States during 2011&#x02013;2015</article-title>. <source>Nicotine Tob Res</source>. <year>2018</year>;<volume>20</volume>(<issue>6</issue>):<fpage>698</fpage>&#x02013;<lpage>706</lpage>.<pub-id pub-id-type="pmid">28575408</pub-id>
</mixed-citation></ref><ref id="R13"><label>13.</label><mixed-citation publication-type="journal"><name><surname>Wang</surname><given-names>TW</given-names></name>, <name><surname>Falvey</surname><given-names>K</given-names></name>, <name><surname>Gammon</surname><given-names>DG</given-names></name>, <etal/>
<article-title>Sales trends in price-discounted cigarettes,large cigars,little cigars,and cigarillos&#x02014;United States, 2011&#x02013;2016</article-title>. <source>Nicotine Tob Res</source>. <year>2018</year>;<volume>20</volume>(<issue>11</issue>):<fpage>1401</fpage>&#x02013;<lpage>1406</lpage>.<pub-id pub-id-type="pmid">29253226</pub-id>
</mixed-citation></ref><ref id="R14"><label>14.</label><mixed-citation publication-type="webpage"><collab>Tobacco Free Kids</collab>. <source>States &#x00026; Localities That Have Restricted the Sale of Flavored Tobacco Products</source>. <comment><ext-link xlink:href="https://www.tobaccofreekids.org/assets/factsheets/0398.pdf" ext-link-type="uri">https://www.tobaccofreekids.org/assets/factsheets/0398.pdf</ext-link>.</comment>
<date-in-citation>Accessed March 19, 2021</date-in-citation>.</mixed-citation></ref><ref id="R15"><label>15.</label><mixed-citation publication-type="webpage"><collab>National Cancer Institute</collab>. <source>Joinpoint Trend Analysis Software</source>. <comment><ext-link xlink:href="https://surveillance.cancer.gov/joinpoint/" ext-link-type="uri">https://surveillance.cancer.gov/joinpoint/</ext-link>.</comment>
<date-in-citation>Accessed September 15, 2021</date-in-citation>.</mixed-citation></ref><ref id="R16"><label>16.</label><mixed-citation publication-type="journal"><name><surname>Gammon</surname><given-names>DG</given-names></name>, <name><surname>Loomis</surname><given-names>BR</given-names></name>, <name><surname>Dench</surname><given-names>DL</given-names></name>, <name><surname>King</surname><given-names>BA</given-names></name>, <name><surname>Fulmer</surname><given-names>EB</given-names></name>, <name><surname>Rogers</surname><given-names>T</given-names></name>. <article-title>Effect of price changes in little cigars and cigarettes on little cigar sales: USA, Q4 2011-Q4 2013</article-title>. <source>Tob Control</source>. <year>2016</year>;<volume>25</volume>(<issue>5</issue>):<fpage>538</fpage>&#x02013;<lpage>544</lpage>.<pub-id pub-id-type="pmid">26357952</pub-id>
</mixed-citation></ref><ref id="R17"><label>17.</label><mixed-citation publication-type="book"><collab>US Department of Health and Human Services (USDHHS)</collab>. <source>Smoking Cessation: A Report of the Surgeon General</source>. <publisher-loc>Atlanta, GA</publisher-loc>: <publisher-name>US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health</publisher-name>; <year>2020</year>.</mixed-citation></ref><ref id="R18"><label>18.</label><mixed-citation publication-type="journal"><name><surname>Jawad</surname><given-names>M</given-names></name>, <name><surname>Lee</surname><given-names>JT</given-names></name>, <name><surname>Glantz</surname><given-names>S</given-names></name>, <name><surname>Millett</surname><given-names>C</given-names></name>. <article-title>Price elasticity of demand of non-cigarette tobacco products: a systematic review and meta-analysis</article-title>. <source>Tob Control</source>. <year>2018</year>;<volume>27</volume>(<issue>6</issue>):<fpage>689</fpage>&#x02013;<lpage>695</lpage>.<pub-id pub-id-type="pmid">29363611</pub-id>
</mixed-citation></ref><ref id="R19"><label>19.</label><mixed-citation publication-type="webpage"><collab>Maine Revised Statutes</collab>. <source>Title 22, Chapter 262-A: Subchapter 5, &#x000a7;1560-D</source>. <comment><ext-link xlink:href="https://www.mainelegislature.org/legis/statutes/22/title22sec1560-D.html" ext-link-type="uri">https://www.mainelegislature.org/legis/statutes/22/title22sec1560-D.html</ext-link>.</comment>
<date-in-citation>Accessed March 19, 2021</date-in-citation>.</mixed-citation></ref><ref id="R20"><label>20.</label><mixed-citation publication-type="journal"><name><surname>Rogers</surname><given-names>T</given-names></name>, <name><surname>Brown</surname><given-names>EM</given-names></name>, <name><surname>McCrae</surname><given-names>TM</given-names></name>, <etal/>
<article-title>Compliance with a sales policy on flavored non-cigarette tobacco products</article-title>. <source>Tob Regul Sci</source>. <year>2017</year>;<volume>3</volume>(<issue>2 Suppl 1</issue>):<fpage>S84</fpage>&#x02013;<lpage>S93</lpage>.<pub-id pub-id-type="pmid">30320155</pub-id>
</mixed-citation></ref></ref-list></back><floats-group><fig position="float" id="F1"><label>Figure 1.</label><caption><p id="P31">Monthly unit sales of cigars by cigar type, January 2016&#x02013;June 2020. Cigar unit sales were calculated by 4-week period. Because of the large variation in monthly unit sales of different cigar products over time, the unit sales depicted on the y-axis were log-transformed to facilitate clearer visualization of trends. However, the labels on the y-axis display the actual unit sales values. A gap was also inserted on y-axis, between 8 million and 13 million for visualization. One unit equals one large cigar, one pack of 20 little cigars, or one pack of 2 cigarillos.</p></caption><graphic xlink:href="nihms-1979079-f0001" position="float"/></fig><fig position="float" id="F2"><label>Figure 2.</label><caption><p id="P32">Average monthly unit price of cigars by cigar type, January 2016&#x02013;June 2020. One unit equals one large cigar, one pack of 20 little cigars, or one pack of 2 cigarillos. Average price per unit was calculated as the total dollar sales divided by total standardized units.</p></caption><graphic xlink:href="nihms-1979079-f0002" position="float"/></fig></floats-group></article>