Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Lang, J. ; Wood, S. C.
Lang, J. ; Wood, S. C. Less -
Description:
The development of vaccines against rare emerging infectious diseases is hampered by many disincentives. In the face of growing in-house expenditures associated with research and development projects in a complex legal and regulatory environment, most pharmaceutical companies prioritize their projects and streamline their product portfolio. Nevertheless, for humanitarian reasons, there is a need to develop niche vaccines for rare diseases not preventable or curable by other means. The U.S. Orphan Drug Act of 1983 and a similar proposal from the European Commission (currently under legislative approval) provide financial and practical incentives for the research and development of drugs to treat rare diseases. In addition, updated epidemiologic information from experts in the field of emerging diseases; increased disease awareness among health professionals, patients, and the general public; a list of priority vaccines; emergence of a dedicated organization with strong leadership; and the long-term pharmacoeconomic viability of orphan products will be key factors in overcoming the complexity of orphan status and the limited need for vaccine.
Subjects:
[+]
Drug Approval European Union Health Policy Humans Orphan Drug Production Vaccines
Source:
Emerg Infect Dis. 5(6):749-756.
Document Type:
Journal Article
Place as Subject:
United States
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:607b41f7a44919eb228de5e004e3d9d87b2e45a765aaf93981ea9cafcd543a11
Download URL:
https://stacks.cdc.gov/view/cdc/14914/cdc_14914_DS1.pdf
File Type:

Supporting Files

• 	10603207.nxml	txt
  	license.txt	txt

More +