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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.3" xml:lang="en" article-type="research-article"><?properties manuscript?><processing-meta base-tagset="archiving" mathml-version="3.0" table-model="xhtml" tagset-family="jats"><restricted-by>pmc</restricted-by></processing-meta><front><journal-meta><journal-id journal-id-type="nlm-journal-id">8704773</journal-id><journal-id journal-id-type="pubmed-jr-id">1656</journal-id><journal-id journal-id-type="nlm-ta">Am J Prev Med</journal-id><journal-id journal-id-type="iso-abbrev">Am J Prev Med</journal-id><journal-title-group><journal-title>American journal of preventive medicine</journal-title></journal-title-group><issn pub-type="ppub">0749-3797</issn><issn pub-type="epub">1873-2607</issn></journal-meta><article-meta><article-id pub-id-type="pmid">30342633</article-id><article-id pub-id-type="pmc">10521032</article-id><article-id pub-id-type="doi">10.1016/j.amepre.2018.07.012</article-id><article-id pub-id-type="manuscript">HHSPA1921294</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Impact of Contraceptive Education on Knowledge and Decision Making: An Updated Systematic Review</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Pazol</surname><given-names>Karen</given-names></name><degrees>PhD, MPH</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Zapata</surname><given-names>Lauren B.</given-names></name><degrees>PhD, MSPH</degrees><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Dehlendorf</surname><given-names>Christine</given-names></name><degrees>MD, MAS</degrees><xref rid="A2" ref-type="aff">2</xref><xref rid="A3" ref-type="aff">3</xref><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Malcolm</surname><given-names>Nikita M.</given-names></name><degrees>MPH</degrees><xref rid="A5" ref-type="aff">5</xref></contrib><contrib contrib-type="author"><name><surname>Rosmarin</surname><given-names>Rachel B.</given-names></name><degrees>MPH</degrees><xref rid="A5" ref-type="aff">5</xref></contrib><contrib contrib-type="author"><name><surname>Frederiksen</surname><given-names>Brittni N.</given-names></name><degrees>PhD, MPH</degrees><xref rid="A6" ref-type="aff">6</xref></contrib></contrib-group><aff id="A1"><label>1</label>Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia</aff><aff id="A2"><label>2</label>Department of Family and Community Medicine, University of California, San Francisco (UCSF), San Francisco, California</aff><aff id="A3"><label>3</label>Obstetrics, Gynecology and Reproductive Sciences, UCSF, San Francisco, California</aff><aff id="A4"><label>4</label>Epidemiology and Biostatistics, UCSF, San Francisco, California</aff><aff id="A5"><label>5</label>Atlas Research, Washington, District of Columbia;</aff><aff id="A6"><label>6</label>Office of Population Affairs, HHS, Rockville, Maryland</aff><author-notes><corresp id="CR1">Address correspondence to: Karen Pazol, PhD, MPH, Division of Reproductive Health, Centers for Disease Control and Prevention, 4770 Buford Highway, MS F-74, Atlanta GA 30341. <email>kpazol@cdc.gov</email>.</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>25</day><month>8</month><year>2023</year></pub-date><pub-date pub-type="ppub"><month>11</month><year>2018</year></pub-date><pub-date pub-type="pmc-release"><day>26</day><month>9</month><year>2023</year></pub-date><volume>55</volume><issue>5</issue><fpage>703</fpage><lpage>715</lpage><abstract id="ABS1"><sec id="S1"><title>Context:</title><p id="P1">Educational interventions can help individuals increase their knowledge of available contraceptive methods, enabling them to make informed decisions and use contraception correctly. This review updates a previous review of contraceptive education.</p></sec><sec id="S2"><title>Evidence acquisition:</title><p id="P2">Multiple databases were searched for articles published March 2011&#x02013;November 2016. Primary outcomes were knowledge, participation in and satisfaction/comfort with decision making, attitudes toward contraception, and selection of more effective methods. Secondary outcomes included contraceptive behaviors and pregnancy. Excluded articles described interventions that had no comparison group, could not be conducted feasibly in a clinic setting, or were conducted outside the U.S. or similar country.</p></sec><sec id="S3"><title>Evidence synthesis:</title><p id="P3">A total of 24,953 articles were identified. Combined with the original review, 37 articles met inclusion criteria and described 31 studies implementing a range of educational approaches (interactive tools, written materials, audio/videotapes, and text messages), with and without healthcare provider feedback, for a total of 36 independent interventions. Of the 31 interventions for which knowledge was assessed, 28 had a positive effect. Fewer were assessed for their effect on attitudes toward contraception, selection of more effective methods, contraceptive behaviors, or pregnancy&#x02014;although increased knowledge was found to mediate additional outcomes (positive attitudes toward contraception and contraceptive continuation).</p></sec><sec id="S4"><title>Conclusions:</title><p id="P4">This systematic review is consistent with evidence from the broader healthcare field in suggesting that a range of interventions can increase knowledge. Future studies should assess what aspects are most effective, the benefits of including provider feedback, and the extent to which educational interventions can facilitate behavior change and attainment of reproductive health goals.</p></sec><sec id="S5"><title>Theme information:</title><p id="P5">This article is part of a theme issue entitled Updating the Systematic Reviews Used to Develop the U.S. Recommendations for Providing Quality Family Planning Services, which is sponsored by the Office of Population Affairs, U.S. Department of Health and Human Services.</p></sec></abstract></article-meta></front><body><sec id="S6"><title>CONTEXT</title><p id="P6">Despite the availability of a wide variety of effective contraceptive methods,<sup><xref rid="R1" ref-type="bibr">1</xref></sup> nearly half of all pregnancies in the U.S. are unintended.<sup><xref rid="R2" ref-type="bibr">2</xref></sup> Unintended pregnancy primarily occurs in women who do not use any contraception or use contraception incorrectly or inconsistently.<sup><xref rid="R3" ref-type="bibr">3</xref>,<xref rid="R4" ref-type="bibr">4</xref></sup> Contraceptive counseling provided by trained healthcare professionals may help sexually active individuals and couples identify contraceptive methods that are the most appropriate and effective for their lifestyle and preferences. An essential component of the counseling process is education. Contraceptive education aims to provide clients the information they need to make informed decisions about their use of contraception and correctly use the contraceptive methods they have selected.</p><p id="P7">The importance of contraceptive education can be seen in the impact of knowledge on method selection and correct and consistent use of contraception. Many women indicate contraceptive effectiveness is among the most important considerations for selecting a method<sup><xref rid="R5" ref-type="bibr">5</xref>&#x02013;<xref rid="R9" ref-type="bibr">9</xref></sup>; consistent with this priority, better knowledge of contraceptive effectiveness is associated with adoption of more effective methods.<sup><xref rid="R10" ref-type="bibr">10</xref>,<xref rid="R11" ref-type="bibr">11</xref></sup> Conversely, inadequate knowledge of contraception is associated with incorrect perceptions of the risks and side effects of contraceptive methods, incorrect or inconsistent use, and method discontinuation.<sup><xref rid="R12" ref-type="bibr">12</xref>&#x02013;<xref rid="R15" ref-type="bibr">15</xref></sup> Despite the importance of education, gaps in contraceptive knowledge are frequently documented.<sup><xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R16" ref-type="bibr">16</xref>,<xref rid="R17" ref-type="bibr">17</xref></sup></p><p id="P8">In 2011, the Centers for Disease Control and Prevention (CDC) and the U.S. Office of Population Affairs conducted a systematic review to better understand the aspects of educational interventions that can promote acquisition of knowledge for informed decision making and correct and continued use of contraception.<sup><xref rid="R18" ref-type="bibr">18</xref></sup> That review informed the development of the 2014 recommendations, Providing Quality Family Planning Services: Recommendations of CDC and the U.S. Office of Population Affairs.<sup><xref rid="R19" ref-type="bibr">19</xref></sup> The objective of this updated review is to summarize the body of evidence that was published subsequently.</p></sec><sec id="S7"><title>EVIDENCE ACQUISITION</title><sec id="S8"><title>Definition of Contraceptive Education</title><p id="P9">This review complements findings of the accompanying review on contraceptive counseling,<sup><xref rid="R20" ref-type="bibr">20</xref></sup> defined as an interactive process between a provider and client intended to help the client achieve a reproductive health goal. This education review focuses more narrowly on the process of helping clients increase their knowledge of contraception so they can make informed decisions about using contraception, and then correctly and consistently use their chosen method.</p></sec><sec id="S9"><title>Development of Key Questions and Search Strategy</title><p id="P10">This systematic review is reported according to the PRISMA checklist.<sup><xref rid="R21" ref-type="bibr">21</xref></sup> The approach used was similar to that implemented in previous reviews<sup><xref rid="R22" ref-type="bibr">22</xref></sup> guided by an analytic framework showing the logical relationships between the population of interest, the interventions, and the outcomes of interest (<xref rid="F1" ref-type="fig">Figure 1</xref>). This review of education interventions primarily focused on short-term outcomes related to contraceptive knowledge and decision making; studies were excluded if the intervention they described focused only on skills or behaviors. Of seven key questions (KQs; <xref rid="T1" ref-type="table">Table 1</xref>), the first five (KQ1&#x02013;KQ5) asked whether educational interventions affected the following: contraceptive knowledge, including correct method use, risks and benefits, side effects, and method effectiveness; participation in decision making; satisfaction/comfort with services and decision making; attitudes toward contraception; and for interventions providing education on the full range of methods, selection of more versus less effective methods (KQ5). KQ6 was expanded from a focus in the original review on health literacy and asked if there were any barriers or facilitators for clinics/clients; KQ7 was added to address unintended consequences.</p><p id="P11">The search strategy included terms common to the other systematic reviews in this series on contraceptive counseling, reminder systems, and patient preferences for contraceptive counseling. Articles were identified from 16 electronic databases (<xref rid="SD1" ref-type="supplementary-material">Appendix Table 1</xref>, available online), and supplemented by hand searches of the bibliographies of identified articles. The initial and updated reviews identified articles published between January 1985&#x02013;February 2011 and March 2011&#x02013;November 2017, respectively.</p><p id="P12">Retrieval and inclusion criteria were developed a priori. Included studies were conducted in a clinic-based setting where family planning services: were provided or assessed an intervention that could be implemented feasibly in a clinic-based setting (e.g., not a multisession course series); contained a comparison group; were conducted in the U.S., Canada, Australia, New Zealand, or a European country categorized as &#x0201c;very high&#x0201d; on the Human Development Index<sup><xref rid="R23" ref-type="bibr">23</xref></sup>; and addressed at least one KQ. Studies focusing primarily on sexually transmitted infections were included only if they incorporated education on condom use to prevent pregnancy. For studies meeting inclusion criteria, outcomes of interest to other systematic reviews in this series (i.e., behavioral outcomes, such as contraceptive use, and long-term outcomes, such as pregnancy) also were evaluated because of their potential to be mediated by knowledge. Outcomes related to the KQs were considered primary outcomes; all other outcomes were considered secondary outcomes.</p></sec><sec id="S10"><title>Data Abstraction</title><p id="P13">Detailed information was abstracted by a team of four abstractors and reviewed by two authors for relevance to contraceptive education; differences were reconciled by consensus. In provider-enhanced interventions, a healthcare provider/educator interacted with the intervention to help participants in at least one group understand or use the information presented. By contrast, in provider-independent interventions a healthcare provider/educator did not go beyond the standard of care to facilitate participant understanding; the participant received the intervention either before or after, rather than during their appointment, and providers were given no specific instructions to help participants understand or make use of information. Studies were classified as evaluating more than one intervention if they included distinct mediums (e.g., written materials versus audio/video) or a provider-independent and a provider-enhanced intervention, each of which was separately compared with a control arm.</p></sec><sec id="S11"><title>Assessment of Study Quality and Data Synthesis</title><p id="P14">Study quality was assessed using a modification of the grading system developed by the U.S. Preventive Services Task Force.<sup><xref rid="R24" ref-type="bibr">24</xref></sup> Studies were first rated based on the U.S. Preventive Services Task Force evidence scale and then specific criteria were used to judge whether the study had high, moderate, or low risk for bias.</p><p id="P15">Data synthesis was primarily qualitative. Meta-analysis was not performed because of the large degree of heterogeneity across studies with respect to study design, study populations, lengths of follow-up, and outcomes measured.</p><p id="P16">Evidence from the initial and updated systematic reviews (<xref rid="F2" ref-type="fig">Figure 2</xref>), including primary and secondary outcomes, is summarized in <xref rid="F3" ref-type="fig">Figure 3</xref> and presented in detail in <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref> (available online). Primary outcomes from the review update are further discussed in the text.</p></sec></sec><sec id="S12"><title>EVIDENCE SYNTHESIS</title><sec id="S13"><title>Search Results</title><p id="P17">The systematic review identified 14,796 unique abstracts. From the title and abstract review, 14,591 articles were excluded and 205 were retrieved; 17 met inclusion criteria.<sup><xref rid="R25" ref-type="bibr">25</xref>&#x02013;<xref rid="R41" ref-type="bibr">41</xref></sup> However, because three studies including the same population and intervention were described in multiple articles,<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> these articles were counted as 14 independent studies. Hand searches of references from included articles identified one additional article<sup><xref rid="R42" ref-type="bibr">42</xref></sup> providing further details on a study from the review update,<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R32" ref-type="bibr">32</xref></sup> and one article,<sup><xref rid="R43" ref-type="bibr">43</xref></sup> providing further details on a study from the original review.<sup><xref rid="R44" ref-type="bibr">44</xref></sup> Together with evidence from the original review,<sup><xref rid="R18" ref-type="bibr">18</xref></sup> 31 studies described in 37 articles are included in this review update (<xref rid="F2" ref-type="fig">Figure 2</xref>).<sup><xref rid="R25" ref-type="bibr">25</xref>&#x02013;<xref rid="R61" ref-type="bibr">61</xref></sup></p><p id="P18">Of the included studies, 17 were RCTs, of which nine were classified as having low,<sup><xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R43" ref-type="bibr">43</xref>,<xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R49" ref-type="bibr">49</xref>,<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref>,<xref rid="R58" ref-type="bibr">58</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> six moderate,<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R35" ref-type="bibr">35</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R42" ref-type="bibr">42</xref>,<xref rid="R46" ref-type="bibr">46</xref></sup> and two high<sup><xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R51" ref-type="bibr">51</xref></sup> risk for bias. Three were non-RCTs with separate groups of intervention and control participants; of these, two were classified as having moderate<sup><xref rid="R45" ref-type="bibr">45</xref>,<xref rid="R54" ref-type="bibr">54</xref></sup> and one high<sup><xref rid="R57" ref-type="bibr">57</xref></sup> risk for bias. Nine used a pre-/post-test study design, of which three were classified as having moderate<sup><xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R37" ref-type="bibr">37</xref>,<xref rid="R41" ref-type="bibr">41</xref></sup> and six high<sup><xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R50" ref-type="bibr">50</xref>,<xref rid="R55" ref-type="bibr">55</xref>,<xref rid="R56" ref-type="bibr">56</xref>,<xref rid="R59" ref-type="bibr">59</xref>,<xref rid="R61" ref-type="bibr">61</xref></sup> risk for bias. Two final studies, also with high risk for bias, used a sequential cohort analysis in which one set of participants was studied prior to implementation of an intervention and was compared with another set of participants studied during the intervention period.<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R48" ref-type="bibr">48</xref></sup></p><p id="P19">Of the 31 studies identified, five included two interventions (one included a written intervention and an audio/video intervention<sup><xref rid="R46" ref-type="bibr">46</xref></sup>; four included a provider-independent and a provider-enhanced intervention<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R43" ref-type="bibr">43</xref>,<xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>) that were each separately compared with a control arm, for a total of 36 interventions. In addition to being assessed for their effects on the a priori outcomes of interest (<xref rid="F3" ref-type="fig">Figure 3</xref>), for three interventions, knowledge gains were evaluated for their further effect on these outcomes, including positive attitudes toward oral contraceptives (OCs)<sup><xref rid="R41" ref-type="bibr">41</xref></sup> and long-acting reversible contraceptives (LARC),<sup><xref rid="R33" ref-type="bibr">33</xref></sup> intention to use OCs,<sup><xref rid="R41" ref-type="bibr">41</xref></sup> and continued use of OCs.<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup></p></sec><sec id="S14"><title>Knowledge</title><p id="P20">The review update identified 12 interventions<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R31" ref-type="bibr">31</xref>&#x02013;<xref rid="R42" ref-type="bibr">42</xref></sup> assessed for their effect on knowledge (KQ1), including knowledge of correct method use, risks and benefits, side effects, and method effectiveness; of these, ten had a significant positive effect.<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R31" ref-type="bibr">31</xref>&#x02013;<xref rid="R37" ref-type="bibr">37</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R41" ref-type="bibr">41</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup> Details are described separately for provider-independent and provider-enhanced interventions.</p><sec id="S15"><title>Provider-independent interventions.</title><p id="P21">The review update identified seven provider-independent interventions.<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R31" ref-type="bibr">31</xref>&#x02013;<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref>&#x02013;<xref rid="R42" ref-type="bibr">42</xref></sup> Of these, three were non-interactive, assessing either a video,<sup><xref rid="R28" ref-type="bibr">28</xref></sup> written materials,<sup><xref rid="R41" ref-type="bibr">41</xref></sup> or text messages<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup>; all three had a significant positive effect. The first<sup><xref rid="R28" ref-type="bibr">28</xref></sup> used a pre-/post-test analysis to assess the effect of a single online video session; the video was based on social and cognitive theories and provided information on intrauterine devices (IUDs). Immediately following the video, participants showed an increase from baseline in their knowledge that the IUD is more effective than the pill (<italic toggle="yes">p</italic>&#x0003c;0.001) and that women who have never had a child can use an IUD (<italic toggle="yes">p</italic>&#x0003c;0.001). The second intervention<sup><xref rid="R41" ref-type="bibr">41</xref></sup> also used a pre-/post-test analysis to examine knowledge among participants who received a comprehensive information brochure on OCs using either a standard evidence-based or a mental models approach. Participants receiving either type of brochure were combined into one group for analysis, which showed an increase in knowledge from baseline to immediate post-test (<italic toggle="yes">p</italic>&#x0003c;0.001), and from baseline to 3 months (<italic toggle="yes">p</italic>&#x0003c;0.001). The third intervention<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup> was evaluated through an RCT and used daily text messages to address key domains of information for OCs (mechanism of action, effectiveness, use, side effects, risks, and benefits). From baseline to 6 months, knowledge scores increased 7% in the intervention versus 3% in the control group (<italic toggle="yes">p</italic>&#x0003c;0.001). While the groups were similar at baseline, at 6 months intervention participants had higher scores related to mechanisms of action (<italic toggle="yes">p</italic>=0.004); side effects (<italic toggle="yes">p</italic>=0.03); effectiveness (<italic toggle="yes">p</italic>&#x0003c;0.001); and potential OC benefits (<italic toggle="yes">p</italic>&#x0003c;0.001).</p><p id="P22">The remaining four provider-independent interventions were interactive tools, each evaluated through an RCT.<sup><xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> Of these, two had a significant positive effect.<sup><xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R33" ref-type="bibr">33</xref></sup> The first<sup><xref rid="R31" ref-type="bibr">31</xref></sup> was based on the theory of planned behavior and was intended to fill gaps in knowledge of LARC, while also providing information on the full range of methods. Knowledge among intervention participants increased from baseline to immediate post-intervention (<italic toggle="yes">p</italic>=0.001).<sup><xref rid="R31" ref-type="bibr">31</xref></sup> The second<sup><xref rid="R33" ref-type="bibr">33</xref></sup> presented information from American College of Obstetricians and Gynecologists contraceptive education pamphlets through an interactive Facebook page with videos, diagrams, and games; control participants were given the same amount of time to review the education pamphlets on the American College of Obstetricians and Gynecologists webpage. Although control participants had higher knowledge scores at baseline (<italic toggle="yes">p</italic>=0.04), Facebook participants showed greater knowledge gains (<italic toggle="yes">p</italic>&#x0003c;0.001) and higher post-test scores (<italic toggle="yes">p</italic>&#x0003c;0.001). Of the two interactive tools that did not have a significant effect, the first<sup><xref rid="R38" ref-type="bibr">38</xref></sup> was based on CDC&#x02019;s U.S. Medical Eligibility Criteria; it allowed participants to explore their contraceptive options and then request a prescription if they wanted a method requiring one; control participants were provided a similar tool with information on chlamydia infection. Immediately following use of their respective tools, intervention and control participants did not differ in their knowledge of relative method effectiveness (LARC versus tubal ligation, <italic toggle="yes">p</italic>=0.26; patch/ring versus birth control pills, <italic toggle="yes">p</italic>=0.16), or the effectiveness of condoms for preventing pregnancy (<italic toggle="yes">p</italic>=0.49). The second tool<sup><xref rid="R40" ref-type="bibr">40</xref></sup> was a smartphone app that allowed participants to access information on a range of contraceptive options. Control participants received standard-of-care counseling from a health educator. Mean scores for knowledge related to the participant&#x02019;s selected method did not differ between the intervention and control groups immediately post-intervention (<italic toggle="yes">p</italic>=0.30).</p><p id="P23">In combination with the original review,<sup><xref rid="R18" ref-type="bibr">18</xref></sup> 21 provider-independent interventions were evaluated for their effect on knowledge. Only one<sup><xref rid="R50" ref-type="bibr">50</xref></sup> of 14<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R41" ref-type="bibr">41</xref>,<xref rid="R43" ref-type="bibr">43</xref>,<xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R46" ref-type="bibr">46</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R49" ref-type="bibr">49</xref>&#x02013;<xref rid="R53" ref-type="bibr">53</xref>,<xref rid="R58" ref-type="bibr">58</xref>&#x02013;<xref rid="R60" ref-type="bibr">60</xref></sup> non-interactive and two<sup><xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> of seven<sup><xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R54" ref-type="bibr">54</xref>,<xref rid="R56" ref-type="bibr">56</xref>,<xref rid="R57" ref-type="bibr">57</xref></sup> interactive interventions did not have a positive effect on at least one outcome (<xref rid="F3" ref-type="fig">Figure 3</xref>; <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online). Only one study compared delivery of the same information in an interactive and a non-interactive format, with participants in the interactive group showing greater knowledge gains.<sup><xref rid="R33" ref-type="bibr">33</xref></sup></p></sec><sec id="S16"><title>Provider-enhanced interventions.</title><p id="P24">The review update identified five provider-enhanced interventions evaluated for their effect on knowledge.<sup><xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R34" ref-type="bibr">34</xref>&#x02013;<xref rid="R37" ref-type="bibr">37</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> Of these, one included a video intervention<sup><xref rid="R35" ref-type="bibr">35</xref></sup> and four used written materials delivered as a script from a healthcare provider.<sup><xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R37" ref-type="bibr">37</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> The video intervention,<sup><xref rid="R35" ref-type="bibr">35</xref></sup> evaluated through an RCT, was a 9-minute DVD presenting information on Nexplanon to abortion patients considering use of this method for the first time. During their appointment, intervention participants viewed the DVD and were then given the opportunity to ask their provider questions. Immediately post-intervention, a higher percentage of intervention versus control participants correctly responded to the effect of implants on mood and skin changes (<italic toggle="yes">p</italic>=0.004), although they did not differ in knowledge related to duration of effectiveness, mechanisms of action, or return to fertility.</p><p id="P25">The first provider-enhanced intervention using written materials<sup><xref rid="R27" ref-type="bibr">27</xref></sup> also was evaluated through an RCT. Providers used a checklist to deliver information determined through a Delphi interview process of 100 gynecologists to be essential for women considering OCs for the first time. Compared with the control group, the intervention group had a higher median knowledge score (<italic toggle="yes">p</italic>&#x0003c;0.001), and for 15 of 22 questions, a higher percentage of participants with correct responses (range by response, <italic toggle="yes">p</italic>&#x0003c;0.05&#x02013;<italic toggle="yes">p</italic>&#x0003c;0.0001). The next two interventions<sup><xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R37" ref-type="bibr">37</xref></sup> similarly included the use of a flip chart to deliver information about emergency contraception during a 5-minute session; the first<sup><xref rid="R36" ref-type="bibr">36</xref></sup> was delivered in the waiting room of a women&#x02019;s clinic, and the second<sup><xref rid="R37" ref-type="bibr">37</xref></sup> was delivered at a grocery store pharmacy; both were evaluated through a pre-/post-test analysis. With the clinic-based intervention, knowledge scores increased from baseline to immediate post-test (<italic toggle="yes">p</italic>&#x0003c;0.001), and remained elevated at 1&#x02013;5 months (<italic toggle="yes">p</italic>-value not reported). With the pharmacy-based intervention, knowledge scores also increased from baseline to immediate post-test (<italic toggle="yes">p</italic>&#x0003c;0.001); at 1&#x02013;3 months follow-up, knowledge scores remained higher than at baseline (<italic toggle="yes">p</italic>=0.014), although they were lower than immediate post-test scores (<italic toggle="yes">p</italic>&#x0003c;0.001). The final provider-enhanced intervention using written materials<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> was evaluated through a sequential cohort analysis. During, but not prior to, the intervention period, providers used a checklist as a reminder to ask patients seeking walk-in services for pregnancy testing or emergency contraception about their pregnancy intentions and any unprotected sex in the past week. Providers then read a short script describing the effectiveness of LARCs relative to other methods, and offered participants emergency contraception or same-day LARC insertion, as appropriate. Immediately following their appointment, participants in the intervention versus the pre-intervention cohort had greater knowledge of LARC effectiveness and duration relative to other methods (<italic toggle="yes">p</italic>&#x0003c;0.05, both outcomes). However, findings related to knowledge of the reversibility of LARCs were mixed, as were findings related to knowledge at 3 months.</p><p id="P26">In combination with the original review,<sup><xref rid="R18" ref-type="bibr">18</xref></sup> a total of ten provider-enhanced interventions were assessed for their effect on knowledge; all ten had a significant positive effect (<xref rid="F3" ref-type="fig">Figure 3</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online).<sup><xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R34" ref-type="bibr">34</xref>&#x02013;<xref rid="R37" ref-type="bibr">37</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R43" ref-type="bibr">43</xref>&#x02013;<xref rid="R45" ref-type="bibr">45</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R55" ref-type="bibr">55</xref></sup></p></sec></sec><sec id="S17"><title>Satisfaction/Comfort With Services and Decision Making</title><p id="P27">Four interventions in the review update were assessed for their effect on satisfaction/comfort with services and decision making (KQ3): three were provider-independent interventions assessed through an RCT,<sup><xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> and one was a provider-enhanced intervention assessed through a sequential cohort analysis.<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> Of the provider-independent interventions, the first<sup><xref rid="R33" ref-type="bibr">33</xref></sup> found that intervention participants given the opportunity to interact with a Facebook page, versus control participants allowed to view pamphlets with the same information, had higher composite scores for satisfaction with the counseling they received (<italic toggle="yes">p</italic>&#x0003c;0.001). By contrast, the second intervention<sup><xref rid="R40" ref-type="bibr">40</xref></sup> found a lower percentage of intervention participants using a smartphone app, versus control participants receiving standard-of-care counseling from a health educator, who reported they were very satisfied with the counseling they received (<italic toggle="yes">p</italic>&#x0003c;0.001). The third provider-independent intervention<sup><xref rid="R26" ref-type="bibr">26</xref></sup> was a video informed by the transtheoretical model of behavioral change designed to increase awareness and dispel misconceptions about LARC. Intervention and control participants did not differ as to whether they reported that they had been given sufficient information (<italic toggle="yes">p</italic>=0.94); they had been able to make their own decision (<italic toggle="yes">p</italic>=0.21); staff had respected their decision (<italic toggle="yes">p</italic>=0.54); or that they were satisfied with their decision (<italic toggle="yes">p</italic>=0.94) and counseling received (<italic toggle="yes">p</italic>=0.82). The one provider-enhanced intervention assessed for its effect on satisfaction was the sequential cohort analysis that was previously described.<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup> In this analysis, a higher percentage of participants in the intervention versus the pre-intervention cohort, having been read a short script on LARC effectiveness, reported that all their questions about birth control had been answered (<italic toggle="yes">p</italic>&#x0003c;0.001), and that they were satisfied with the discussion (<italic toggle="yes">p</italic>=0.03).</p><p id="P28">In combination with the original review,<sup><xref rid="R18" ref-type="bibr">18</xref></sup> seven interventions were assessed for their effect on satisfaction/comfort with services and decision making (<xref rid="F3" ref-type="fig">Figure 3</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online). Findings remained mixed. Six of the seven interventions were provider-independent interventions, with three finding a significant positive effect,<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R48" ref-type="bibr">48</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> two finding no effect,<sup><xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R51" ref-type="bibr">51</xref></sup> and one finding a significant negative effect<sup><xref rid="R40" ref-type="bibr">40</xref></sup>; only one provider-enhanced intervention was identified.<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref></sup></p></sec><sec id="S18"><title>Positive Attitudes Toward Contraception</title><p id="P29">Two provider-independent interventions were identified in the review update that assessed attitudes toward contraception (KQ4), both with a positive effect. The first,<sup><xref rid="R41" ref-type="bibr">41</xref></sup> evaluated through a pre-/post-test analysis of a comprehensive information brochure, as described earlier, resulted in an immediate post-test increase in participants&#x02019; scores for a positive attitude about OCs (<italic toggle="yes">p</italic>&#x0003c;0.001); although scores dropped after 3 months, they remained higher than at baseline (<italic toggle="yes">p</italic>=0.036). Moreover, the increase was positively associated with knowledge scores, both immediately post-test (<italic toggle="yes">r</italic>=0.284, <italic toggle="yes">p</italic>=0.001) and at the 3-month follow-up (<italic toggle="yes">r</italic>=0.206, <italic toggle="yes">p</italic>=0.022). The second intervention,<sup><xref rid="R33" ref-type="bibr">33</xref></sup> also described earlier, resulted in a significantly greater proportion of participants in the interactive Facebook group expressing a preference for implants in particular (<italic toggle="yes">p</italic>&#x0003c;0.01), or LARC in general (<italic toggle="yes">p</italic>&#x0003c;0.01). Moreover, knowledge was again an important factor. For both study arms combined, greater increases in knowledge (4%, 12%, 24%, and 36%) were associated with a greater increase in the RR of stating a preference for LARC (RRs: 1.06, 1.19, 1.43, and 1.71, respectively, 95% CIs in <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online).</p><p id="P30">In combination with the original review,<sup><xref rid="R18" ref-type="bibr">18</xref></sup> six different interventions assessed the effect of educational tools on attitudes toward contraception (<xref rid="F3" ref-type="fig">Figure 3</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online). Except for one intervention using written materials alone,<sup><xref rid="R46" ref-type="bibr">46</xref></sup> each had a positive effect.<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R41" ref-type="bibr">41</xref>,<xref rid="R46" ref-type="bibr">46</xref>,<xref rid="R58" ref-type="bibr">58</xref>,<xref rid="R61" ref-type="bibr">61</xref></sup></p></sec><sec id="S19"><title>Selection of More Effective Contraceptive Methods</title><p id="P31">The review update identified four interventions, assessed through three RCTs<sup><xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> that addressed the selection of more versus less effective contraceptive methods and also provided education on the full range of contraceptive options (KQ5; <xref rid="F3" ref-type="fig">Figure 3</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online). Two of these interventions were provider-independent interactive tools described previously: one filled gaps in knowledge of LARC, while also providing information on the full range of contraceptive options,<sup><xref rid="R31" ref-type="bibr">31</xref></sup> and the other presented methods in the order of effectiveness.<sup><xref rid="R40" ref-type="bibr">40</xref></sup> Neither resulted in differences in LARC uptake among intervention versus control participants (Gilliam et al.<sup><xref rid="R31" ref-type="bibr">31</xref></sup>: <italic toggle="yes">p</italic>=0.77, Sridhar and colleagues<sup><xref rid="R40" ref-type="bibr">40</xref></sup>: <italic toggle="yes">p</italic>=0.75). The final study<sup><xref rid="R30" ref-type="bibr">30</xref></sup> found a positive effect of both a provider-independent and a provider-enhanced intervention. This study assessed a computer-based contraceptive assessment module in which intervention participants received either a generic list of methods (provider-independent), or a list of methods tailored to their responses, which they were instructed to share with their healthcare provider (provider-enhanced). Among participants in the control group who were not exposed to any tool, 65% selected an effective method (i.e., injectables, pills, patches, or rings), and 15% selected a highly effective method (i.e., IUD or implant); in comparison to these percentage for the control group, selection of effective and highly effective methods, respectively, was greater in both the generic (78% and 24%, <italic toggle="yes">p</italic>&#x0003c;0.001) and tailored information arm (75% and 22%, <italic toggle="yes">p</italic>&#x0003c;0.001), and both intervention arms had increased odds relative to controls of selecting an effective method (generic vs control: OR=1.74, 95% CI=1.35, 2.25; tailored vs control: OR=1.56, 95% CI=1.23, 1.98).</p><p id="P32">No studies from the original review<sup><xref rid="R18" ref-type="bibr">18</xref></sup> evaluated the effect of educational interventions on selection of more effective methods.</p></sec><sec id="S20"><title>Educational Attainment as a Facilitator or Barrier</title><p id="P33">The review update identified four interventions (two provider-independent<sup><xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R43" ref-type="bibr">43</xref></sup> and two provider-enhanced<sup><xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R43" ref-type="bibr">43</xref></sup>), assessed through two RCTs<sup><xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R43" ref-type="bibr">43</xref></sup> and one pre-/post-test analysis,<sup><xref rid="R36" ref-type="bibr">36</xref></sup> that asked whether a participant&#x02019;s education level impacted knowledge gains (KQ6; <xref rid="F3" ref-type="fig">Figure 3</xref>, <xref rid="SD2" ref-type="supplementary-material">Appendix Table 2</xref>, available online). One study assessed the interaction of patient education with use of text messages,<sup><xref rid="R32" ref-type="bibr">32</xref></sup> one with written materials delivered by a provider using a flip chart,<sup><xref rid="R36" ref-type="bibr">36</xref></sup> and one with use of either a summary card or full-length brochure, delivered with or without interactive questions delivered by a provider.<sup><xref rid="R43" ref-type="bibr">43</xref></sup> With three of the interventions, knowledge gains were similar across education categories (text messages: <italic toggle="yes">p</italic>=0.49; summary card or full-length brochure without interactive questions: <italic toggle="yes">p</italic>=0.9; or with interactive questions: <italic toggle="yes">p</italic>=0.6).<sup><xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R43" ref-type="bibr">43</xref></sup> Education interacted with the final intervention in which providers delivered information using a flip chart: Increases in knowledge were greater for participants with a high school education versus those with some college education or above (136% vs 51%, <italic toggle="yes">p</italic>=0.016).<sup><xref rid="R36" ref-type="bibr">36</xref></sup></p><p id="P34">No studies from the original review<sup><xref rid="R18" ref-type="bibr">18</xref></sup> assessed the effect of educational attainment on knowledge gains.</p></sec></sec><sec id="S21"><title>DISCUSSION</title><p id="P35">The initial and updated reviews identified 31 independent educational interventions using a variety of mediums (i.e., written materials, audio/videotapes, text messages, and interactive tools) assessed for their effect on knowledge.<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R31" ref-type="bibr">31</xref>&#x02013;<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R49" ref-type="bibr">49</xref>&#x02013;<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R54" ref-type="bibr">54</xref>&#x02013;<xref rid="R60" ref-type="bibr">60</xref></sup> All but three<sup><xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R50" ref-type="bibr">50</xref></sup> of the 31 interventions had a significant positive effect, and 16<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R35" ref-type="bibr">35</xref>,<xref rid="R42" ref-type="bibr">42</xref>&#x02013;<xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R46" ref-type="bibr">46</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R49" ref-type="bibr">49</xref>,<xref rid="R52" ref-type="bibr">52</xref>&#x02013;<xref rid="R54" ref-type="bibr">54</xref>,<xref rid="R58" ref-type="bibr">58</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> of those with a positive effect were evaluated through RCTs characterized by low/moderate risk for bias. These findings are consistent with the initial review<sup><xref rid="R18" ref-type="bibr">18</xref></sup> and other systematic reviews from the broader healthcare field,<sup><xref rid="R62" ref-type="bibr">62</xref>,<xref rid="R63" ref-type="bibr">63</xref></sup> in suggesting a wide range of educational interventions can help increase client understanding.</p><p id="P36">Although the original review<sup><xref rid="R18" ref-type="bibr">18</xref></sup> did not identify any interventions assessed for their interaction with client educational attainment, the review update identified four such interventions. With three,<sup><xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R36" ref-type="bibr">36</xref>,<xref rid="R43" ref-type="bibr">43</xref></sup> increases in knowledge did not differ by educational attainment; the benefit of the fourth was greater for participants with less versus more education.<sup><xref rid="R36" ref-type="bibr">36</xref></sup> Although the educational level targeted by these interventions was not described, it is possible they were effective across educational levels because they were designed for individuals with lower levels of educational attainment. This would be consistent with recommendations from evidence-based tool kits from the broader healthcare field suggesting that health education materials be easy to interpret by clients with a fourth- to sixth-grade reading level,<sup><xref rid="R64" ref-type="bibr">64</xref>&#x02013;<xref rid="R66" ref-type="bibr">66</xref></sup> and that certain basic strategies can be used to simplify information and promote comprehension for all clients. These strategies include appropriately presenting numeric quantities (e.g., by using common denominators and natural frequencies, such as &#x0201c;1 in 100 versus 5 in 100&#x0201d;),<sup><xref rid="R67" ref-type="bibr">67</xref>&#x02013;<xref rid="R79" ref-type="bibr">79</xref></sup> limiting the amount of information presented, and highlighting important facts by placing them first.<sup><xref rid="R80" ref-type="bibr">80</xref>&#x02013;<xref rid="R82" ref-type="bibr">82</xref></sup> Given the initial review identified only two studies that assessed the use of such strategies for simplifying the presentation of information (both of which had mixed results),<sup><xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> and no additional studies were identified in the review update, more detailed research specific to contraception is warranted.</p><p id="P37">Few conclusions can be drawn with respect to the secondary outcomes. For intentions to use contraception, the one secondary outcome considered a short-term outcome in the accompanying reviews, there was a positive effect in all but one<sup><xref rid="R35" ref-type="bibr">35</xref></sup> of six interventions.<sup><xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R35" ref-type="bibr">35</xref>,<xref rid="R41" ref-type="bibr">41</xref>,<xref rid="R49" ref-type="bibr">49</xref>,<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup> However, with respect to medium- and long-term outcomes (i.e., contraceptive use, including correct, consistent, or continued use, and pregnancy), a positive effect was found in a smaller proportion of interventions, which may be because broader counseling interventions are needed to address outcomes associated with behavioral change and reproductive health goals.<sup><xref rid="R83" ref-type="bibr">83</xref></sup> Nonetheless, with three interventions, knowledge mediated additional outcomes of interest, including positive attitudes toward OCs<sup><xref rid="R41" ref-type="bibr">41</xref></sup> or LARCs,<sup><xref rid="R33" ref-type="bibr">33</xref></sup> intentions to use OCs,<sup><xref rid="R41" ref-type="bibr">41</xref></sup> and continued use of OCs.<sup><xref rid="R25" ref-type="bibr">25</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup></p><p id="P38">Finally, this update adds to evidence about the extent to which educational interventions are more effective with input from a health provider/educator. With respect to knowledge (KQ1), all ten provider-enhanced versus 18 of 21 provider-independent interventions had a significant positive effect. However, for satisfaction/comfort with decision making and services (KQ3), positive attitudes (KQ4), and selection of more effective methods (KQ5), only one provider-enhanced intervention was identified, thus providing little basis for comparison. Of note, however, four RCTs with low risk for bias (three from the original review<sup><xref rid="R44" ref-type="bibr">44</xref>,<xref rid="R47" ref-type="bibr">47</xref>,<xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup> and one from the review update<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref></sup>) were identified comparing the same intervention with and without feedback from a healthcare provider. Results were mixed. In the first, participants who attended a face-to-face session with a health educator, versus those who received similar information through a video, made greater knowledge gains relative to controls.<sup><xref rid="R47" ref-type="bibr">47</xref></sup> In the second, participants who received either a simplified tool or a standard leaflet showed increases in knowledge relative to controls; however, although the increase relative to controls was even greater when the simplified tool was paired with interactive questions from a provider, there was no additive effect with the standard leaflet.<sup><xref rid="R44" ref-type="bibr">44</xref></sup> In the third RCT, the addition of a facilitator-led discussion session was no more effective than a videotape alone for increasing knowledge relative to controls,<sup><xref rid="R52" ref-type="bibr">52</xref></sup> but did result in a higher proportion of participants redeeming vouchers for free condoms.<sup><xref rid="R53" ref-type="bibr">53</xref></sup> The final RCT, described above,<sup><xref rid="R30" ref-type="bibr">30</xref></sup> found that a contraceptive assessment tool was similarly effective at promoting selection of more effective methods with and without provider enhancement. However, only participants in the provider enhanced group showed higher odds relative to controls of using their selected method correctly and continuing at 4 months.<sup><xref rid="R29" ref-type="bibr">29</xref></sup></p><p id="P39">One reason for the mixed results on provider feedback may be that educational tools by themselves are only effective for some types of learning. Research from other areas of health care has demonstrated the effectiveness of active learning techniques.<sup><xref rid="R84" ref-type="bibr">84</xref>&#x02013;<xref rid="R87" ref-type="bibr">87</xref></sup> Such learning can be readily incorporated into interactive tools, many of which have been developed recently for contraception and included in this review, with mixed results.<sup><xref rid="R29" ref-type="bibr">29</xref>&#x02013;<xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R38" ref-type="bibr">38</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> However, these tools may not enhance more complex interactions. For instance, the teach-back method, in which clients restate the most important messages in their own words, has been shown to ensure comprehension,<sup><xref rid="R88" ref-type="bibr">88</xref>,<xref rid="R89" ref-type="bibr">89</xref></sup> and was recently used to lower IUD discontinuation rates.<sup><xref rid="R90" ref-type="bibr">90</xref></sup> Similarly, interactive tools by themselves may not be sufficient for other components of counseling that build upon knowledge, such as skill building or evaluating options in light of individual needs and preferences. More recently, contraceptive decision aids have been developed as provider tools for improving contraceptive counseling.<sup><xref rid="R91" ref-type="bibr">91</xref>,<xref rid="R92" ref-type="bibr">92</xref></sup> Research is needed to assess whether contraceptive decision aids developed for this purpose can further promote satisfaction with services, and attainment of behavioral and reproductive health goals.</p><sec id="S22"><title>Limitations</title><p id="P40">This evidence summarizing the impact of educational interventions has several limitations, which should be considered when interpreting the evidence. Although several high-quality studies were identified for assessing the impact of educational interventions on knowledge, fewer were identified for the remaining primary outcomes targeted by contraceptive education. Seven studies assessed satisfaction/comfort with services and decision making, of which four were RCTs with low/moderate risk,<sup><xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> and three had high risk for bias.<sup><xref rid="R34" ref-type="bibr">34</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R48" ref-type="bibr">48</xref>,<xref rid="R51" ref-type="bibr">51</xref></sup> Of the five studies assessing positive attitudes toward contraception, three were RCTs with low/moderate risk for bias,<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R46" ref-type="bibr">46</xref>,<xref rid="R58" ref-type="bibr">58</xref></sup> and two had a high risk for bias or a less rigorous design.<sup><xref rid="R41" ref-type="bibr">41</xref>,<xref rid="R61" ref-type="bibr">61</xref></sup> Only three studies were identified that assessed selection of more effective methods, although all were RCTs with low/moderate risk for bias.<sup><xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R31" ref-type="bibr">31</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> The authors were unable to identify any studies that addressed participation in the decision-making process. Additionally, as noted above, there was insufficient evidence to assess strategies for simplifying the presentation of information or the importance of input from a healthcare provider. Lastly, it is possible that additional articles meeting the inclusion criteria for this systematic review have been published since the updated search of the literature.</p></sec></sec><sec id="S23"><title>CONCLUSIONS</title><p id="P41">This systematic review provides clear evidence that a wide range of educational interventions can effectively increase client understanding. Although the small number of studies addressing the remaining outcomes limited additional conclusions, some studies demonstrated that increases in knowledge can mediate additional outcomes of interest. Future studies should assess what aspects of interventions for increasing knowledge and promoting informed decision making are most effective with respect to contraception, the benefits of including provider feedback, and the extent to which educational interventions can facilitate behavior change and attainment of reproductive health goals.</p></sec><sec sec-type="supplementary-material" id="SM1"><title>Supplementary Material</title><supplementary-material id="SD1" position="float" content-type="local-data"><label>Appendix Table 1</label><media xlink:href="NIHMS1921294-supplement-Appendix_Table_1.pdf" id="d64e1614" position="anchor"/></supplementary-material><supplementary-material id="SD2" position="float" content-type="local-data"><label>Appendix Table 2</label><media xlink:href="NIHMS1921294-supplement-Appendix_Table_2.pdf" id="d64e1617" position="anchor"/></supplementary-material></sec></body><back><ack id="S24"><title>ACKNOWLEDGMENTS</title><p id="P42">The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention or the Office of Population Affairs.</p><p id="P43">This product was supported, in part, by a contract between the Office of Population Affairs and Atlas Research, Inc. (HHSP233201500126I, HHSP233201450040A).</p></ack><fn-group><fn fn-type="COI-statement" id="FN1"><p id="P44">No conflicts of interest or financial disclosures were reported by the authors of this paper.</p></fn><fn id="FN2"><p id="P45">THEME NOTE</p><p id="P46">This article is part of a theme issue entitled Updating the Systematic Reviews Used to Develop the U.S. Recommendations for Providing Quality Family Planning Services, which is sponsored by the Office of Population Affairs, U.S. Department of Health and Human Services.</p></fn><fn id="FN3"><p id="P47">SUPPLEMENTAL MATERIAL</p><p id="P48">Supplemental materials associated with this article can be found in the online version at doi:<ext-link xlink:href="10.1016/j.amepre.2018.07.012" ext-link-type="doi">10.1016/j.amepre.2018.07.012</ext-link>.</p></fn></fn-group><ref-list><title>REFERENCES</title><ref id="R1"><label>1.</label><mixed-citation publication-type="book"><name><surname>Hatcher</surname><given-names>R</given-names></name>, <name><surname>Trussell</surname><given-names>J</given-names></name>, <name><surname>Nelson</surname><given-names>A</given-names></name>, <name><surname>Cates</surname><given-names>W</given-names></name>, <name><surname>Kowal</surname><given-names>D</given-names></name>, <name><surname>Policar</surname><given-names>M</given-names></name>. <source>Contraceptive Technology</source>
<publisher-loc>Atlanta, GA</publisher-loc>: <publisher-name>Ardent Media</publisher-name>, <year>2011</year>.</mixed-citation></ref><ref id="R2"><label>2.</label><mixed-citation publication-type="journal"><name><surname>Finer</surname><given-names>LB</given-names></name>, <name><surname>Zolna</surname><given-names>MR</given-names></name>. <article-title>Declines in unintended pregnancy in the United States, 2008&#x02013;2011.</article-title>
<source>N Engl J Med</source>
<year>2016</year>;<volume>374</volume>(<issue>9</issue>):<fpage>843</fpage>&#x02013;<lpage>852</lpage>. <pub-id pub-id-type="doi">10.1056/NEJMsa1506575</pub-id>.<pub-id pub-id-type="pmid">26962904</pub-id></mixed-citation></ref><ref id="R3"><label>3.</label><mixed-citation publication-type="book"><name><surname>Gold</surname><given-names>RB</given-names></name>, <name><surname>Sonfield</surname><given-names>A</given-names></name>, <name><surname>Richards</surname><given-names>CL</given-names></name>, <name><surname>Frost</surname><given-names>JJ</given-names></name>. <source>Next Steps for America&#x02019;s Family Planning Program: Leveraging the Potential of Medicaid and Title X in an Evolving Health Care System</source>
<publisher-loc>New York, NY</publisher-loc>: <publisher-name>Guttmacher Institute</publisher-name>, <year>2009</year>.</mixed-citation></ref><ref id="R4"><label>4.</label><mixed-citation publication-type="journal"><name><surname>Finer</surname><given-names>LB</given-names></name>, <name><surname>Zolna</surname><given-names>MR</given-names></name>. <article-title>Unintended pregnancy in the United States: incidence and disparities, 2006.</article-title>
<source>Contraception</source>
<year>2011</year>;<volume>84</volume>(<issue>5</issue>):<fpage>478</fpage>&#x02013;<lpage>485</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2011.07.013</pub-id>.<pub-id pub-id-type="pmid">22018121</pub-id></mixed-citation></ref><ref id="R5"><label>5.</label><mixed-citation publication-type="journal"><name><surname>Stanwood</surname><given-names>NL</given-names></name>, <name><surname>Bradley</surname><given-names>KA</given-names></name>. <article-title>Young pregnant women&#x02019;s knowledge of modern intrauterine devices.</article-title>
<source>Obstet Gynecol</source>
<year>2006</year>;<volume>108</volume>(<issue>6</issue>):<fpage>1417</fpage>&#x02013;<lpage>1422</lpage>. <pub-id pub-id-type="doi">10.1097/01.AOG.0000245447.56585.a0</pub-id>.<pub-id pub-id-type="pmid">17138775</pub-id></mixed-citation></ref><ref id="R6"><label>6.</label><mixed-citation publication-type="journal"><name><surname>Grady</surname><given-names>WR</given-names></name>, <name><surname>Klepinger</surname><given-names>DH</given-names></name>, <name><surname>Nelson-Wally</surname><given-names>A</given-names></name>. <article-title>Contraceptive characteristics: the perceptions and priorities of men and women.</article-title>
<source>Fam Plann Perspect</source>
<year>1999</year>;<volume>31</volume>(<issue>4</issue>):<fpage>168</fpage>&#x02013;<lpage>175</lpage>. <pub-id pub-id-type="doi">10.2307/2991589</pub-id>.<pub-id pub-id-type="pmid">10435215</pub-id></mixed-citation></ref><ref id="R7"><label>7.</label><mixed-citation publication-type="journal"><name><surname>Forrest</surname><given-names>JD</given-names></name>. <article-title>U.S. women&#x02019;s perceptions of and attitudes about the IUD.</article-title>
<source>Obstet Gynecol Surv</source>
<year>1996</year>;<volume>51</volume>(<issue>12</issue>):<fpage>(suppl)S30</fpage>&#x02013;<lpage>S34</lpage>. <pub-id pub-id-type="doi">10.1097/00006254-199612000-00012</pub-id>.</mixed-citation></ref><ref id="R8"><label>8.</label><mixed-citation publication-type="journal"><name><surname>Steiner</surname><given-names>MJ</given-names></name>, <name><surname>Trussell</surname><given-names>J</given-names></name>, <name><surname>Mehta</surname><given-names>N</given-names></name>, <name><surname>Condon</surname><given-names>S</given-names></name>, <name><surname>Subramaniam</surname><given-names>S</given-names></name>, <name><surname>Bourne</surname><given-names>D</given-names></name>. <article-title>Communicating contraceptive effectiveness: a randomized controlled trial to inform a World Health Organization family planning handbook.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2006</year>;<volume>195</volume>(<issue>1</issue>):<fpage>85</fpage>&#x02013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajog.2005.12.053</pub-id>.<pub-id pub-id-type="pmid">16626610</pub-id></mixed-citation></ref><ref id="R9"><label>9.</label><mixed-citation publication-type="journal"><name><surname>Jackson</surname><given-names>AV</given-names></name>, <name><surname>Karasek</surname><given-names>D</given-names></name>, <name><surname>Dehlendorf</surname><given-names>C</given-names></name>, <name><surname>Foster</surname><given-names>DG</given-names></name>. <article-title>Racial and ethnic differences in women&#x02019;s preferences for features of contraceptive methods.</article-title>
<source>Contraception</source>
<year>2016</year>;<volume>93</volume>(<issue>5</issue>):<fpage>406</fpage>&#x02013;<lpage>411</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2015.12.010</pub-id>.<pub-id pub-id-type="pmid">26738619</pub-id></mixed-citation></ref><ref id="R10"><label>10.</label><mixed-citation publication-type="journal"><name><surname>Dempsey</surname><given-names>AR</given-names></name>, <name><surname>Billingsley</surname><given-names>CC</given-names></name>, <name><surname>Savage</surname><given-names>AH</given-names></name>, <name><surname>Korte</surname><given-names>JE</given-names></name>. <article-title>Predictors of long-acting reversible contraception use among unmarried young adults.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2012</year>;<volume>206</volume>(<issue>6</issue>):<fpage>526.e1</fpage>&#x02013;<lpage>526.e5</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajog.2012.02.014</pub-id>.</mixed-citation></ref><ref id="R11"><label>11.</label><mixed-citation publication-type="journal"><name><surname>Eisenberg</surname><given-names>DL</given-names></name>, <name><surname>Secura</surname><given-names>GM</given-names></name>, <name><surname>Madden</surname><given-names>TE</given-names></name>, <name><surname>Allsworth</surname><given-names>JE</given-names></name>, <name><surname>Zhao</surname><given-names>Q</given-names></name>, <name><surname>Peipert</surname><given-names>JF</given-names></name>. <article-title>Knowledge of contraceptive effectiveness.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2012</year>;<volume>206</volume>(<issue>6</issue>):<fpage>479.e1</fpage>&#x02013;<lpage>479.e9.</lpage>
<pub-id pub-id-type="doi">10.1016/j.ajog.2012.04.012</pub-id>.</mixed-citation></ref><ref id="R12"><label>12.</label><mixed-citation publication-type="journal"><name><surname>Gardner</surname><given-names>J</given-names></name>, <name><surname>Miller</surname><given-names>L</given-names></name>. <article-title>Promoting the safety and use of hormonal contraceptives.</article-title>
<source>J Womens Health (Larchmt)</source>
<year>2005</year>;<volume>14</volume>(<issue>1</issue>):<fpage>53</fpage>&#x02013;<lpage>60</lpage>. <pub-id pub-id-type="doi">10.1089/jwh.2005.14.53</pub-id>.<pub-id pub-id-type="pmid">15692278</pub-id></mixed-citation></ref><ref id="R13"><label>13.</label><mixed-citation publication-type="journal"><name><surname>Grimes</surname><given-names>DA</given-names></name>, <name><surname>Schulz</surname><given-names>KF</given-names></name>. <article-title>Nonspecific side effects of oral contraceptives: nocebo or noise?</article-title>
<source>Contraception</source>
<year>2011</year>;<volume>83</volume>(<issue>1</issue>):<fpage>5</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2010.06.010</pub-id>.<pub-id pub-id-type="pmid">21134497</pub-id></mixed-citation></ref><ref id="R14"><label>14.</label><mixed-citation publication-type="journal"><name><surname>Frost</surname><given-names>JJ</given-names></name>, <name><surname>Duberstein Lindberg</surname><given-names>L</given-names></name>, <name><surname>Finer</surname><given-names>LB</given-names></name>. <article-title>Young adults&#x02019; contraceptive knowledge, norms and attitudes: associations with risk of unintended pregnancy.</article-title>
<source>Perspect Sex Reprod Health</source>
<year>2012</year>;<volume>44</volume>(<issue>2</issue>):<fpage>107</fpage>&#x02013;<lpage>116</lpage>. <pub-id pub-id-type="doi">10.1363/4410712</pub-id>.<pub-id pub-id-type="pmid">22681426</pub-id></mixed-citation></ref><ref id="R15"><label>15.</label><mixed-citation publication-type="journal"><name><surname>Rickert</surname><given-names>VI</given-names></name>, <name><surname>Berenson</surname><given-names>AB</given-names></name>, <name><surname>Williamson</surname><given-names>AJ</given-names></name>, <name><surname>Wiemann</surname><given-names>CM</given-names></name>. <article-title>Immediate recall of oral contraceptive instructions: implications for providers.</article-title>
<source>Am J Obstet Gynecol</source>
<year>1999</year>;<volume>180</volume>(<issue>6, pt 1</issue>):<fpage>1399</fpage>&#x02013;<lpage>1406</lpage>. <pub-id pub-id-type="doi">10.1016/S0002-9378(99)70025-6</pub-id>.<pub-id pub-id-type="pmid">10368477</pub-id></mixed-citation></ref><ref id="R16"><label>16.</label><mixed-citation publication-type="journal"><name><surname>Rocca</surname><given-names>CH</given-names></name>, <name><surname>Harper</surname><given-names>CC</given-names></name>. <article-title>Do racial and ethnic differences in contraceptive attitudes and knowledge explain disparities in method use</article-title><source>? Perspect Sex Reprod Health</source>
<year>2012</year>;<volume>44</volume>(<issue>3</issue>):<fpage>150</fpage>&#x02013;<lpage>158</lpage>. <pub-id pub-id-type="doi">10.1363/4415012</pub-id>.<pub-id pub-id-type="pmid">22958659</pub-id></mixed-citation></ref><ref id="R17"><label>17.</label><mixed-citation publication-type="journal"><name><surname>Hall</surname><given-names>KS</given-names></name>, <name><surname>Casta&#x000f1;o</surname><given-names>PM</given-names></name>, <name><surname>Stone</surname><given-names>PW</given-names></name>, <name><surname>Westhoff</surname><given-names>C</given-names></name>. <article-title>Measuring oral contraceptive knowledge: a review of research findings and limitations.</article-title>
<source>Patient Educ Couns</source>
<year>2010</year>;<volume>81</volume>(<issue>3</issue>):<fpage>388</fpage>&#x02013;<lpage>394</lpage>. <pub-id pub-id-type="doi">10.1016/j.pec.2010.10.016</pub-id>.<pub-id pub-id-type="pmid">21084170</pub-id></mixed-citation></ref><ref id="R18"><label>18.</label><mixed-citation publication-type="journal"><name><surname>Pazol</surname><given-names>K</given-names></name>, <name><surname>Zapata</surname><given-names>LB</given-names></name>, <name><surname>Tregear</surname><given-names>SJ</given-names></name>, <name><surname>Mautone-Smith</surname><given-names>N</given-names></name>, <name><surname>Gavin</surname><given-names>LE</given-names></name>. <article-title>Impact of contraceptive education on contraceptive knowledge and decision making: a systematic review.</article-title>
<source>Am J Prev Med</source>
<year>2015</year>;<volume>49</volume>(<issue>2</issue>):<fpage>(suppl)S46</fpage>&#x02013;<lpage>S56</lpage>. <pub-id pub-id-type="doi">10.1016/j.amepre.2015.03.031</pub-id>.</mixed-citation></ref><ref id="R19"><label>19.</label><mixed-citation publication-type="journal"><collab>Centers for Disease Control and Prevention (CDC).</collab>
<article-title>Providing quality family planning services: recommendations of the CDC and the U.S. Office of Population Affairs.</article-title>
<source>MMWR Recomm Rep</source><year>2014</year>;<volume>63</volume>(<issue>4</issue>):<fpage>1</fpage>&#x02013;<lpage>54</lpage>.</mixed-citation></ref><ref id="R20"><label>20.</label><mixed-citation publication-type="journal"><name><surname>Zapata</surname><given-names>LB</given-names></name>, <name><surname>Pazol</surname><given-names>K</given-names></name>, <name><surname>Dehlendorf</surname><given-names>C</given-names></name>, <etal/>
<article-title>Contraceptive counseling in clinical settings: an updated systematic review.</article-title>
<source>Am J Prev Med</source>
<year>2018</year>;<volume>55</volume>(<issue>5</issue>):<fpage>677</fpage>&#x02013;<lpage>690</lpage>.<pub-id pub-id-type="pmid">30342631</pub-id></mixed-citation></ref><ref id="R21"><label>21.</label><mixed-citation publication-type="journal"><name><surname>Moher</surname><given-names>D</given-names></name>, <name><surname>Liberati</surname><given-names>A</given-names></name>, <name><surname>Tetzlaff</surname><given-names>J</given-names></name>, <name><surname>Altman</surname><given-names>DG</given-names></name>. <article-title>Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.</article-title>
<source>BMJ</source>
<year>2009</year>;<volume>339</volume>:<fpage>b2535</fpage>
<pub-id pub-id-type="doi">10.1136/bmj.b2535</pub-id>.<pub-id pub-id-type="pmid">19622551</pub-id></mixed-citation></ref><ref id="R22"><label>22.</label><mixed-citation publication-type="journal"><name><surname>Tregear</surname><given-names>SJ</given-names></name>, <name><surname>Gavin</surname><given-names>LE</given-names></name>, <name><surname>Williams</surname><given-names>JR</given-names></name>. <article-title>Systematic review evidence methodology: providing quality family planning services.</article-title>
<source>Am J Prev Med</source>
<year>2015</year>;<volume>49</volume>(<issue>2</issue>):<fpage>(suppl) S23</fpage>&#x02013;<lpage>S30</lpage>. <pub-id pub-id-type="doi">10.1016/j.amepre.2015.03.033</pub-id>.</mixed-citation></ref><ref id="R23"><label>23.</label><mixed-citation publication-type="webpage"><collab>UN Development Programme.</collab>
<source>Human development report 2016: human development for everyone</source>
<comment><ext-link xlink:href="http://hdr.undp.org/en/2016-report/" ext-link-type="uri">http://hdr.undp.org/en/2016-report/</ext-link>. Published 2016. Accessed</comment>
<date-in-citation>October 31, 2017</date-in-citation>.</mixed-citation></ref><ref id="R24"><label>24.</label><mixed-citation publication-type="journal"><name><surname>Harris</surname><given-names>RP</given-names></name>, <name><surname>Helfand</surname><given-names>M</given-names></name>, <name><surname>Woolf</surname><given-names>SH</given-names></name>, <etal/>
<article-title>Current methods of the U.S. Preventive Services Task Force: a review of the process.</article-title>
<source>Am J Prev Med</source>
<year>2001</year>;<comment>(suppl)</comment><volume>20</volume>(<issue>3</issue>):<fpage>21</fpage>&#x02013;<lpage>35</lpage>. <pub-id pub-id-type="doi">10.1016/S0749-3797(01)00261-6</pub-id>.</mixed-citation></ref><ref id="R25"><label>25.</label><mixed-citation publication-type="journal"><name><surname>Castano</surname><given-names>PM</given-names></name>, <name><surname>Bynum</surname><given-names>JY</given-names></name>, <name><surname>Andres</surname><given-names>R</given-names></name>, <name><surname>Lara</surname><given-names>M</given-names></name>, <name><surname>Westhoff</surname><given-names>C</given-names></name>. <article-title>Effect of daily text messages on oral contraceptive continuation: a randomized controlled trial.</article-title>
<source>Obstet Gynecol</source>
<year>2012</year>;<volume>119</volume>(<issue>1</issue>):<fpage>14</fpage>&#x02013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.1097/AOG.0b013e31823d4167</pub-id>.<pub-id pub-id-type="pmid">22143257</pub-id></mixed-citation></ref><ref id="R26"><label>26.</label><mixed-citation publication-type="journal"><name><surname>Davidson</surname><given-names>AS</given-names></name>, <name><surname>Whitaker</surname><given-names>AK</given-names></name>, <name><surname>Martins</surname><given-names>SL</given-names></name>, <etal/>
<article-title>Impact of a theory-based video on initiation of long-acting reversible contraception after abortion.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2015</year>;<volume>212</volume>(<issue>3</issue>):<fpage>310.e1</fpage>&#x02013;<lpage>310.e7</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajog.2014.09.027</pub-id>.</mixed-citation></ref><ref id="R27"><label>27.</label><mixed-citation publication-type="journal"><name><surname>de Reilhac</surname><given-names>P</given-names></name>, <name><surname>Plu-Bureau</surname><given-names>G</given-names></name>, <name><surname>Serfaty</surname><given-names>D</given-names></name>, <name><surname>Letombe</surname><given-names>B</given-names></name>, <name><surname>Gondry</surname><given-names>J</given-names></name>, <name><surname>Christin-Maitre</surname><given-names>S</given-names></name>. <article-title>The CORALIE study: improving patient education to help new users better understand their oral contraceptive.</article-title>
<source>Eur J Contracept Reprod Health Care</source>
<year>2016</year>;<volume>21</volume>(<issue>5</issue>):<fpage>388</fpage>&#x02013;<lpage>394</lpage>. <pub-id pub-id-type="doi">10.1080/13625187.2016.1217323</pub-id>.<pub-id pub-id-type="pmid">27530618</pub-id></mixed-citation></ref><ref id="R28"><label>28.</label><mixed-citation publication-type="journal"><name><surname>Garbers</surname><given-names>S</given-names></name>, <name><surname>Chiasson</surname><given-names>MA</given-names></name>, <name><surname>Baum</surname><given-names>R</given-names></name>, <name><surname>Tobier</surname><given-names>N</given-names></name>, <name><surname>Ventura</surname><given-names>A</given-names></name>, <name><surname>Hirshfield</surname><given-names>S</given-names></name>. <article-title>Get It and Forget It&#x0201d;: online evaluation of a theory-based IUD educational video in English and Spanish</article-title>. <source>Contraception</source>
<year>2015</year>;<volume>91</volume>(<issue>1</issue>):<fpage>76</fpage>&#x02013;<lpage>79</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2014.09.002</pub-id>.<pub-id pub-id-type="pmid">25262375</pub-id></mixed-citation></ref><ref id="R29"><label>29.</label><mixed-citation publication-type="journal"><name><surname>Garbers</surname><given-names>S</given-names></name>, <name><surname>Meserve</surname><given-names>A</given-names></name>, <name><surname>Kottke</surname><given-names>M</given-names></name>, <name><surname>Hatcher</surname><given-names>R</given-names></name>, <name><surname>Chiasson</surname><given-names>MA</given-names></name>. <article-title>Tailored health messaging improves contraceptive continuation and adherence: results from a randomized controlled trial.</article-title>
<source>Contraception</source>
<year>2012</year>;<volume>86</volume>(<issue>5</issue>):<fpage>536</fpage>&#x02013;<lpage>542</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2012.02.005</pub-id>.<pub-id pub-id-type="pmid">22445439</pub-id></mixed-citation></ref><ref id="R30"><label>30.</label><mixed-citation publication-type="journal"><name><surname>Garbers</surname><given-names>S</given-names></name>, <name><surname>Meserve</surname><given-names>A</given-names></name>, <name><surname>Kottke</surname><given-names>M</given-names></name>, <name><surname>Hatcher</surname><given-names>R</given-names></name>, <name><surname>Ventura</surname><given-names>A</given-names></name>, <name><surname>Chiasson</surname><given-names>MA</given-names></name>. <article-title>Randomized controlled trial of a computer-based module to improve contraceptive method choice.</article-title>
<source>Contraception</source>
<year>2012</year>;<volume>86</volume>(<issue>4</issue>):<fpage>383</fpage>&#x02013;<lpage>390</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2012.01.013</pub-id>.<pub-id pub-id-type="pmid">22402258</pub-id></mixed-citation></ref><ref id="R31"><label>31.</label><mixed-citation publication-type="journal"><name><surname>Gilliam</surname><given-names>ML</given-names></name>, <name><surname>Martins</surname><given-names>SL</given-names></name>, <name><surname>Bartlett</surname><given-names>E</given-names></name>, <name><surname>Mistretta</surname><given-names>SQ</given-names></name>, <name><surname>Holl</surname><given-names>JL</given-names></name>. <article-title>Development and testing of an iOS waiting room &#x0201c;app&#x0201d; for contraceptive counseling in a Title X family planning clinic.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2014</year>;<volume>211</volume>(<issue>5</issue>):<fpage>481.e1</fpage>&#x02013;<lpage>481.e8</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajog.2014.05.034</pub-id>.</mixed-citation></ref><ref id="R32"><label>32.</label><mixed-citation publication-type="journal"><name><surname>Hall</surname><given-names>KS</given-names></name>, <name><surname>Westhoff</surname><given-names>CL</given-names></name>, <name><surname>Castano</surname><given-names>PM</given-names></name>. <article-title>The impact of an educational text message intervention on young urban women&#x02019;s knowledge of oral contraception.</article-title>
<source>Contraception</source>
<year>2013</year>;<volume>87</volume>(<issue>4</issue>):<fpage>449</fpage>&#x02013;<lpage>454</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2012.09.004</pub-id>.<pub-id pub-id-type="pmid">23062523</pub-id></mixed-citation></ref><ref id="R33"><label>33.</label><mixed-citation publication-type="journal"><name><surname>Kofinas</surname><given-names>JD</given-names></name>, <name><surname>Varrey</surname><given-names>A</given-names></name>, <name><surname>Sapra</surname><given-names>KJ</given-names></name>, <name><surname>Kanj</surname><given-names>RV</given-names></name>, <name><surname>Chervenak</surname><given-names>FA</given-names></name>, <name><surname>Asfaw</surname><given-names>T</given-names></name>. <article-title>Adjunctive social media for more effective contraceptive counseling: a randomized controlled trial.</article-title>
<source>Obstet Gynecol</source>
<year>2014</year>;<volume>123</volume>(<issue>4</issue>):<fpage>763</fpage>&#x02013;<lpage>770</lpage>. <pub-id pub-id-type="doi">10.1097/AOG.0000000000000172</pub-id>.<pub-id pub-id-type="pmid">24785602</pub-id></mixed-citation></ref><ref id="R34"><label>34.</label><mixed-citation publication-type="journal"><name><surname>Lee</surname><given-names>J</given-names></name>, <name><surname>Papic</surname><given-names>M</given-names></name>, <name><surname>Baldauf</surname><given-names>E</given-names></name>, <name><surname>Updike</surname><given-names>G</given-names></name>, <name><surname>Schwarz</surname><given-names>EB</given-names></name>. <article-title>A checklist approach to caring for women seeking pregnancy testing: effects on contraceptive knowledge and use.</article-title>
<source>Contraception</source>
<year>2015</year>;<volume>91</volume>(<issue>2</issue>):<fpage>143</fpage>&#x02013;<lpage>149</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2014.11.003</pub-id>.<pub-id pub-id-type="pmid">25492313</pub-id></mixed-citation></ref><ref id="R35"><label>35.</label><mixed-citation publication-type="journal"><name><surname>Michie</surname><given-names>L</given-names></name>, <name><surname>Cameron</surname><given-names>ST</given-names></name>, <name><surname>Glasier</surname><given-names>A</given-names></name>, <name><surname>Johnstone</surname><given-names>A</given-names></name>. <article-title>Giving information about the contraceptive implant using a DVD: is it acceptable and informative? A pilot randomised study.</article-title>
<source>J Fam Plann Reprod Health Care</source>
<year>2016</year>;<volume>42</volume>(<issue>3</issue>):<fpage>194</fpage>&#x02013;<lpage>200</lpage>. <pub-id pub-id-type="doi">10.1136/jfprhc-2015-101186</pub-id>.<pub-id pub-id-type="pmid">26250853</pub-id></mixed-citation></ref><ref id="R36"><label>36.</label><mixed-citation publication-type="journal"><name><surname>Ragland</surname><given-names>D</given-names></name>, <name><surname>Payakachat</surname><given-names>N</given-names></name>, <name><surname>Ounpraseuth</surname><given-names>S</given-names></name>, <name><surname>Pate</surname><given-names>A</given-names></name>, <name><surname>Harrod</surname><given-names>SE</given-names></name>, <name><surname>Ott</surname><given-names>RE</given-names></name>. <article-title>Emergency contraception counseling: an opportunity for pharmacists.</article-title>
<source>J Am Pharm Assoc (2003)</source>
<year>2011</year>;<volume>51</volume>(<issue>6</issue>):<fpage>756</fpage>&#x02013;<lpage>761</lpage>. <pub-id pub-id-type="doi">10.1331/JAPhA.2011.10157</pub-id>.<pub-id pub-id-type="pmid">22068198</pub-id></mixed-citation></ref><ref id="R37"><label>37.</label><mixed-citation publication-type="journal"><name><surname>Ragland</surname><given-names>D</given-names></name>, <name><surname>Payakachat</surname><given-names>N</given-names></name>, <name><surname>Stafford</surname><given-names>RA</given-names></name>. <article-title>Emergency contraception counseling in a retail pharmacy setting: a pilot study.</article-title>
<source>J Pharm Pract</source>
<year>2015</year>;<volume>28</volume>(<issue>3</issue>):<fpage>261</fpage>&#x02013;<lpage>265</lpage>. <pub-id pub-id-type="doi">10.1177/0897190013516507</pub-id>.<pub-id pub-id-type="pmid">24429294</pub-id></mixed-citation></ref><ref id="R38"><label>38.</label><mixed-citation publication-type="journal"><name><surname>Schwarz</surname><given-names>EB</given-names></name>, <name><surname>Burch</surname><given-names>EJ</given-names></name>, <name><surname>Parisi</surname><given-names>SM</given-names></name>, <etal/>
<article-title>Computer-assisted provision of hormonal contraception in acute care settings.</article-title>
<source>Contraception</source>
<year>2013</year>;<volume>87</volume> (<issue>2</issue>):<fpage>242</fpage>&#x02013;<lpage>250</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2012.07.003</pub-id>.<pub-id pub-id-type="pmid">22921686</pub-id></mixed-citation></ref><ref id="R39"><label>39.</label><mixed-citation publication-type="journal"><name><surname>Schwarz</surname><given-names>EB</given-names></name>, <name><surname>Papic</surname><given-names>M</given-names></name>, <name><surname>Parisi</surname><given-names>SM</given-names></name>, <name><surname>Baldauf</surname><given-names>E</given-names></name>, <name><surname>Rapkin</surname><given-names>R</given-names></name>, <name><surname>Updike</surname><given-names>G</given-names></name>. <article-title>Routine counseling about intrauterine contraception for women seeking emergency contraception.</article-title>
<source>Contraception</source>
<year>2014</year>;<volume>90</volume>(<issue>1</issue>):<fpage>66</fpage>&#x02013;<lpage>71</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2014.02.007</pub-id>.<pub-id pub-id-type="pmid">24674042</pub-id></mixed-citation></ref><ref id="R40"><label>40.</label><mixed-citation publication-type="journal"><name><surname>Sridhar</surname><given-names>A</given-names></name>, <name><surname>Chen</surname><given-names>A</given-names></name>, <name><surname>Forbes</surname><given-names>ER</given-names></name>, <name><surname>Glik</surname><given-names>D</given-names></name>. <article-title>Mobile application for information on reversible contraception: a randomized controlled trial.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2015</year>;<volume>212</volume>(<issue>6</issue>):<fpage>774.e1</fpage>&#x02013;<lpage>774.e7</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajog.2015.01.011</pub-id>.</mixed-citation></ref><ref id="R41"><label>41.</label><mixed-citation publication-type="journal"><name><surname>Vogt</surname><given-names>C</given-names></name>, <name><surname>Schaefer</surname><given-names>M</given-names></name>. <article-title>Knowledge matters&#x02014;impact of two types of information brochure on contraceptive knowledge, attitudes and intentions.</article-title>
<source>Eur J Contracept Reprod Health Care</source>
<year>2012</year>;<volume>17</volume>(<issue>2</issue>):<fpage>135</fpage>&#x02013;<lpage>143</lpage>. <pub-id pub-id-type="doi">10.3109/13625187.2011.643837</pub-id>.<pub-id pub-id-type="pmid">22200343</pub-id></mixed-citation></ref><ref id="R42"><label>42.</label><mixed-citation publication-type="journal"><name><surname>Hall</surname><given-names>KS</given-names></name>, <name><surname>Castano</surname><given-names>PM</given-names></name>, <name><surname>Westhoff</surname><given-names>CL</given-names></name>. <article-title>The influence of oral contraceptive knowledge on oral contraceptive continuation among young women.</article-title>
<source>J Womens Health (Larchmt)</source>
<year>2014</year>;<volume>23</volume>(<issue>7</issue>):<fpage>596</fpage>&#x02013;<lpage>601</lpage>. <pub-id pub-id-type="doi">10.1089/jwh.2013.4574</pub-id>.<pub-id pub-id-type="pmid">24571282</pub-id></mixed-citation></ref><ref id="R43"><label>43.</label><mixed-citation publication-type="journal"><name><surname>Little</surname><given-names>P</given-names></name>, <name><surname>Griffin</surname><given-names>S</given-names></name>, <name><surname>Dickson</surname><given-names>N</given-names></name>, <name><surname>Sadler</surname><given-names>C</given-names></name>, <name><surname>Kelly</surname><given-names>J</given-names></name>. <article-title>Unwanted pregnancy and contraceptive knowledge: identifying vulnerable groups from a randomized controlled trial of educational interventions.</article-title>
<source>Fam Pract</source>
<year>2001</year>;<volume>18</volume>(<issue>4</issue>):<fpage>449</fpage>&#x02013;<lpage>453</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/18.4.449</pub-id>.<pub-id pub-id-type="pmid">11477055</pub-id></mixed-citation></ref><ref id="R44"><label>44.</label><mixed-citation publication-type="journal"><name><surname>Little</surname><given-names>P</given-names></name>, <name><surname>Griffin</surname><given-names>S</given-names></name>, <name><surname>Kelly</surname><given-names>J</given-names></name>, <name><surname>Dickson</surname><given-names>N</given-names></name>, <name><surname>Sadler</surname><given-names>C</given-names></name>. <article-title>Effect of educational leaflets and questions on knowledge of contraception in women taking the combined contraceptive pill: randomised controlled trial.</article-title>
<source>BMJ</source>
<year>1998</year>;<volume>316</volume>(<issue>7149</issue>):<fpage>1948</fpage>&#x02013;<lpage>1952</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.316.7149.1948</pub-id>.<pub-id pub-id-type="pmid">9641933</pub-id></mixed-citation></ref><ref id="R45"><label>45.</label><mixed-citation publication-type="journal"><name><surname>Chewning</surname><given-names>B</given-names></name>, <name><surname>Mosena</surname><given-names>P</given-names></name>, <name><surname>Wilson</surname><given-names>D</given-names></name>, <etal/>
<article-title>Evaluation of a computerized contraceptive decision aid for adolescent patients.</article-title>
<source>Patient Educ Couns</source>
<year>1999</year>;<volume>38</volume>(<issue>3</issue>):<fpage>227</fpage>&#x02013;<lpage>239</lpage>. <pub-id pub-id-type="doi">10.1016/S0738-3991(99)00014-2</pub-id>.<pub-id pub-id-type="pmid">10865688</pub-id></mixed-citation></ref><ref id="R46"><label>46.</label><mixed-citation publication-type="journal"><name><surname>Deijen</surname><given-names>JB</given-names></name>, <name><surname>Kornaat</surname><given-names>H</given-names></name>. <article-title>The influence of type of information, somatization, and locus of control on attitude, knowledge, and compliance with respect to the triphasic oral contraceptive Tri-Minulet.</article-title>
<source>Contraception</source>
<year>1997</year>;<volume>56</volume>(<issue>1</issue>):<fpage>31</fpage>&#x02013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1016/S0010-7824(97)00071-1</pub-id>.<pub-id pub-id-type="pmid">9306029</pub-id></mixed-citation></ref><ref id="R47"><label>47.</label><mixed-citation publication-type="journal"><name><surname>DeLamater</surname><given-names>J</given-names></name>, <name><surname>Wagstaff</surname><given-names>DA</given-names></name>, <name><surname>Havens</surname><given-names>KK</given-names></name>. <article-title>The impact of a culturally appropriate STD/AIDS education intervention on black male adolescents&#x02019; sexual and condom use behavior.</article-title>
<source>Health Educ Behav</source>
<year>2000</year>;<volume>27</volume> (<issue>4</issue>):<fpage>454</fpage>&#x02013;<lpage>470</lpage>. <pub-id pub-id-type="doi">10.1177/109019810002700408</pub-id>.<pub-id pub-id-type="pmid">10929753</pub-id></mixed-citation></ref><ref id="R48"><label>48.</label><mixed-citation publication-type="journal"><name><surname>Johnson</surname><given-names>LK</given-names></name>, <name><surname>Edelman</surname><given-names>A</given-names></name>, <name><surname>Jensen</surname><given-names>J</given-names></name>. <article-title>Patient satisfaction and the impact of written material about postpartum contraceptive decisions.</article-title>
<source>Am J Obstet Gynecol</source>
<year>2003</year>;<volume>188</volume>(<issue>5</issue>):<fpage>1202</fpage>&#x02013;<lpage>1204</lpage>. <pub-id pub-id-type="doi">10.1067/mob.2003.308</pub-id>.<pub-id pub-id-type="pmid">12748478</pub-id></mixed-citation></ref><ref id="R49"><label>49.</label><mixed-citation publication-type="journal"><name><surname>Kirby</surname><given-names>D</given-names></name>, <name><surname>Harvey</surname><given-names>PD</given-names></name>, <name><surname>Claussenius</surname><given-names>D</given-names></name>, <name><surname>Novar</surname><given-names>M</given-names></name>. <article-title>A direct mailing to teenage males about condom use: its impact on knowledge, attitudes and sexual behavior.</article-title>
<source>Fam Plann Perspect</source>
<year>1989</year>;<volume>21</volume>(<issue>1</issue>):<fpage>12</fpage>&#x02013;<lpage>18</lpage>. <pub-id pub-id-type="doi">10.2307/2135413</pub-id>.<pub-id pub-id-type="pmid">2703031</pub-id></mixed-citation></ref><ref id="R50"><label>50.</label><mixed-citation publication-type="journal"><name><surname>Lindenberg</surname><given-names>CS</given-names></name>, <name><surname>Solorzano</surname><given-names>RM</given-names></name>, <name><surname>Bear</surname><given-names>D</given-names></name>, <name><surname>Strickland</surname><given-names>O</given-names></name>, <name><surname>Galvis</surname><given-names>C</given-names></name>, <name><surname>Pittman</surname><given-names>K</given-names></name>. <article-title>Reducing substance use and risky sexual behavior among young, low-income, Mexican-American women: comparison of two interventions.</article-title>
<source>Appl Nurs Res</source>
<year>2002</year>;<volume>15</volume>(<issue>3</issue>):<fpage>137</fpage>&#x02013;<lpage>148</lpage>. <pub-id pub-id-type="doi">10.1053/apnr.2002.34141</pub-id>.<pub-id pub-id-type="pmid">12173165</pub-id></mixed-citation></ref><ref id="R51"><label>51.</label><mixed-citation publication-type="journal"><name><surname>Mason</surname><given-names>V</given-names></name>, <name><surname>McEwan</surname><given-names>A</given-names></name>, <name><surname>Walker</surname><given-names>D</given-names></name>, <name><surname>Barrett</surname><given-names>S</given-names></name>, <name><surname>James</surname><given-names>D</given-names></name>. <article-title>The use of video information in obtaining consent for female sterilisation: a randomised study.</article-title>
<source>BJOG</source>
<year>2003</year>;<volume>110</volume>(<issue>12</issue>):<fpage>1062</fpage>&#x02013;<lpage>1071</lpage>. <pub-id pub-id-type="doi">10.1111/j.1471-0528.2003.03041.x</pub-id>.<pub-id pub-id-type="pmid">14664877</pub-id></mixed-citation></ref><ref id="R52"><label>52.</label><mixed-citation publication-type="journal"><name><surname>O&#x02019;Donnell</surname><given-names>L</given-names></name>, <name><surname>San Doval</surname><given-names>A</given-names></name>, <name><surname>Duran</surname><given-names>R</given-names></name>, <name><surname>O&#x02019;Donnell</surname><given-names>CR</given-names></name>. <article-title>The effectiveness of video-based interventions in promoting condom acquisition among STD clinic patients.</article-title>
<source>Sex Transm Dis</source>
<year>1995</year>;<volume>22</volume>(<issue>2</issue>):<fpage>97</fpage>&#x02013;<lpage>103</lpage>. <pub-id pub-id-type="doi">10.1097/00007435-199503000-00004</pub-id>.<pub-id pub-id-type="pmid">7624818</pub-id></mixed-citation></ref><ref id="R53"><label>53.</label><mixed-citation publication-type="journal"><name><surname>O&#x02019;Donnell</surname><given-names>LN</given-names></name>, <name><surname>Doval</surname><given-names>AS</given-names></name>, <name><surname>Duran</surname><given-names>R</given-names></name>, <name><surname>O&#x02019;Donnell</surname><given-names>C</given-names></name>. <article-title>Video-based sexually transmitted disease patient education: its impact on condom acquisition.</article-title>
<source>Am J Public Health</source>
<year>1995</year>;<volume>85</volume>(<issue>6</issue>):<fpage>817</fpage>&#x02013;<lpage>822</lpage>. <pub-id pub-id-type="doi">10.2105/AJPH.85.6.817</pub-id>.<pub-id pub-id-type="pmid">7762716</pub-id></mixed-citation></ref><ref id="R54"><label>54.</label><mixed-citation publication-type="journal"><name><surname>Paperny</surname><given-names>DM</given-names></name>, <name><surname>Starn</surname><given-names>JR</given-names></name>. <article-title>Adolescent pregnancy prevention by health education computer games: computer-assisted instruction of knowledge and attitudes.</article-title>
<source>Pediatrics</source>
<year>1989</year>;<volume>83</volume>(<issue>5</issue>):<fpage>742</fpage>&#x02013;<lpage>752</lpage>.<pub-id pub-id-type="pmid">2654867</pub-id></mixed-citation></ref><ref id="R55"><label>55.</label><mixed-citation publication-type="journal"><name><surname>Pedrazzini</surname><given-names>AE</given-names></name>, <name><surname>McGowan</surname><given-names>H</given-names></name>, <name><surname>Lucking</surname><given-names>L</given-names></name>, <name><surname>Johanson</surname><given-names>RJ</given-names></name>. <article-title>The trouble with sex&#x02014;it always gets in the way&#x0201d;: an evaluation of a peer-produced teenage pregnancy video.</article-title>
<source>Br J Fam Plann</source>
<year>2000</year>;<volume>26</volume>(<issue>3</issue>):<fpage>131</fpage>&#x02013;<lpage>135</lpage>. <pub-id pub-id-type="doi">10.1783/147118900101194544</pub-id>.<pub-id pub-id-type="pmid">10920287</pub-id></mixed-citation></ref><ref id="R56"><label>56.</label><mixed-citation publication-type="journal"><name><surname>Reis</surname><given-names>J</given-names></name>, <name><surname>Tymchyshyn</surname><given-names>P</given-names></name>. <article-title>A longitudinal evaluation of computer-assisted instruction on contraception for college students.</article-title>
<source>Adolescence</source>
<year>1992</year>;<volume>27</volume> (<issue>108</issue>):<fpage>803</fpage>&#x02013;<lpage>811</lpage>.<pub-id pub-id-type="pmid">1471560</pub-id></mixed-citation></ref><ref id="R57"><label>57.</label><mixed-citation publication-type="journal"><name><surname>Roberto</surname><given-names>AJ</given-names></name>, <name><surname>Zimmerman</surname><given-names>RS</given-names></name>, <name><surname>Carlyle</surname><given-names>KE</given-names></name>, <name><surname>Abner</surname><given-names>EL</given-names></name>, <name><surname>Cupp</surname><given-names>PK</given-names></name>, <name><surname>Hansen</surname><given-names>GL</given-names></name>. <article-title>The effects of a computer-based pregnancy, STD, and HIV prevention intervention: a nine-school trial.</article-title>
<source>Health Commun</source>
<year>2007</year>;<volume>21</volume> (<issue>2</issue>):<fpage>115</fpage>&#x02013;<lpage>124</lpage>. <pub-id pub-id-type="doi">10.1080/10410230701306990</pub-id>.<pub-id pub-id-type="pmid">17523857</pub-id></mixed-citation></ref><ref id="R58"><label>58.</label><mixed-citation publication-type="journal"><name><surname>Schwarz</surname><given-names>EB</given-names></name>, <name><surname>Gerbert</surname><given-names>B</given-names></name>, <name><surname>Gonzales</surname><given-names>R</given-names></name>. <article-title>Computer-assisted provision of emergency contraception a randomized controlled trial</article-title><source>. J Gen Intern Med</source>
<year>2008</year>;<volume>23</volume>(<issue>6</issue>):<fpage>794</fpage>&#x02013;<lpage>799</lpage>. <pub-id pub-id-type="doi">10.1007/s11606-008-0609-x</pub-id>.<pub-id pub-id-type="pmid">18398664</pub-id></mixed-citation></ref><ref id="R59"><label>59.</label><mixed-citation publication-type="journal"><name><surname>Smith</surname><given-names>LF</given-names></name>, <name><surname>Whitfield</surname><given-names>MJ</given-names></name>. <article-title>Women&#x02019;s knowledge of taking oral contraceptive pills correctly and of emergency contraception: effect of providing information leaflets in general practice.</article-title>
<source>Br J Gen Pract</source>
<year>1995</year>;<volume>45</volume>(<issue>397</issue>):<fpage>409</fpage>&#x02013;<lpage>414</lpage>.<pub-id pub-id-type="pmid">7576845</pub-id></mixed-citation></ref><ref id="R60"><label>60.</label><mixed-citation publication-type="journal"><name><surname>Steiner</surname><given-names>MJ</given-names></name>, <name><surname>Dalebout</surname><given-names>S</given-names></name>, <name><surname>Condon</surname><given-names>S</given-names></name>, <name><surname>Dominik</surname><given-names>R</given-names></name>, <name><surname>Trussell</surname><given-names>J</given-names></name>. <article-title>Understanding risk: a randomized controlled trial of communicating contraceptive effectiveness.</article-title>
<source>Obstet Gynecol</source>
<year>2003</year>;<volume>102</volume>(<issue>4</issue>):<fpage>709</fpage>&#x02013;<lpage>717</lpage>. <pub-id pub-id-type="doi">10.1097/00006250-200310000-00012</pub-id>.<pub-id pub-id-type="pmid">14551000</pub-id></mixed-citation></ref><ref id="R61"><label>61.</label><mixed-citation publication-type="journal"><name><surname>Whitaker</surname><given-names>AK</given-names></name>, <name><surname>Terplan</surname><given-names>M</given-names></name>, <name><surname>Gold</surname><given-names>MA</given-names></name>, <name><surname>Johnson</surname><given-names>LM</given-names></name>, <name><surname>Creinin</surname><given-names>MD</given-names></name>, <name><surname>Harwood</surname><given-names>B</given-names></name>. <article-title>Effect of a brief educational intervention on the attitudes of young women toward the intrauterine device.</article-title>
<source>J Pediatr Adolesc Gynecol</source>
<year>2010</year>;<volume>23</volume>(<issue>2</issue>):<fpage>116</fpage>&#x02013;<lpage>120</lpage>. <pub-id pub-id-type="doi">10.1016/j.jpag.2009.09.012</pub-id>.<pub-id pub-id-type="pmid">19896397</pub-id></mixed-citation></ref><ref id="R62"><label>62.</label><mixed-citation publication-type="journal"><name><surname>Trevena</surname><given-names>LJ</given-names></name>, <name><surname>Davey</surname><given-names>HM</given-names></name>, <name><surname>Barratt</surname><given-names>A</given-names></name>, <name><surname>Butow</surname><given-names>P</given-names></name>, <name><surname>Caldwell</surname><given-names>P</given-names></name>. <article-title>A systematic review on communicating with patients about evidence.</article-title>
<source>J Eval Clin Pract</source>
<year>2006</year>;<volume>12</volume>(<issue>1</issue>):<fpage>13</fpage>&#x02013;<lpage>23</lpage>. <pub-id pub-id-type="doi">10.1111/j.1365-2753.2005.00596.x</pub-id>.<pub-id pub-id-type="pmid">16422776</pub-id></mixed-citation></ref><ref id="R63"><label>63.</label><mixed-citation publication-type="journal"><name><surname>Stacey</surname><given-names>D</given-names></name>, <name><surname>Bennett</surname><given-names>CL</given-names></name>, <name><surname>Barry</surname><given-names>MJ</given-names></name>, <etal/>
<article-title>Decision aids for people facing health treatment or screening decisions.</article-title>
<source>Cochrane Database Syst Rev</source>
<year>2011</year>;<volume>10</volume>
<fpage>CD001431</fpage>
<pub-id pub-id-type="doi">10.1002/14651858.CD001431.pub3</pub-id>.</mixed-citation></ref><ref id="R64"><label>64.</label><mixed-citation publication-type="webpage"><collab>Centers for Medicare and Medicaid Services.</collab>
<source>Toolkit for making written material clear and effective</source>
<comment><ext-link xlink:href="http://www.cms.gov/WrittenMaterialsTool-kit/01_Overview.asp#TopOfPage" ext-link-type="uri">www.cms.gov/WrittenMaterialsTool-kit/01_Overview.asp#TopOfPage</ext-link>. Published 2011.</comment></mixed-citation></ref><ref id="R65"><label>65.</label><mixed-citation publication-type="webpage"><collab>HHS, Office of Disease Prevention and Health Promotion.</collab>
<source>Health literacy online: a guide for simplifying the user experience</source>
<comment><ext-link xlink:href="https://health.gov/healthliteracyonline/" ext-link-type="uri">https://health.gov/healthliteracyonline/</ext-link>. Published 2016.</comment></mixed-citation></ref><ref id="R66"><label>66.</label><mixed-citation publication-type="book"><name><surname>DeWalt</surname><given-names>D</given-names></name>, <name><surname>Callahan</surname><given-names>L</given-names></name>, <name><surname>Hawk</surname><given-names>V</given-names></name>, <etal/>
<source>Health Literacy Universal Precautions Toolkit</source>
<publisher-name>AHRQ Publication No. 10-0046-EF.</publisher-name>
<comment><ext-link xlink:href="http://nchealth-literacy.org/toolkit/" ext-link-type="uri">http://nchealth-literacy.org/toolkit/</ext-link>. Published 2010.</comment></mixed-citation></ref><ref id="R67"><label>67.</label><mixed-citation publication-type="journal"><name><surname>Berry</surname><given-names>DC</given-names></name>. <article-title>Informing people about the risks and benefits of medicines: implications for the safe and effective use of medicinal products.</article-title>
<source>Curr Drug Saf</source>
<year>2006</year>;<volume>1</volume>(<issue>1</issue>):<fpage>121</fpage>&#x02013;<lpage>126</lpage>. <pub-id pub-id-type="doi">10.2174/157488606775252638</pub-id>.<pub-id pub-id-type="pmid">18690922</pub-id></mixed-citation></ref><ref id="R68"><label>68.</label><mixed-citation publication-type="journal"><name><surname>Berry</surname><given-names>DC</given-names></name>, <name><surname>Raynor</surname><given-names>DK</given-names></name>, <name><surname>Knapp</surname><given-names>P</given-names></name>, <name><surname>Bersellini</surname><given-names>E</given-names></name>. <article-title>Patients&#x02019; understanding of risk associated with medication use: impact of European Commission guidelines and other risk scales.</article-title>
<source>Drug Saf</source>
<year>2003</year>;<volume>26</volume>(<issue>1</issue>):<fpage>1</fpage>&#x02013;<lpage>11</lpage>. <pub-id pub-id-type="doi">10.2165/00002018-200326010-00001</pub-id>.<pub-id pub-id-type="pmid">12495359</pub-id></mixed-citation></ref><ref id="R69"><label>69.</label><mixed-citation publication-type="journal"><name><surname>Edwards</surname><given-names>A</given-names></name>, <name><surname>Elwyn</surname><given-names>G</given-names></name>, <name><surname>Mulley</surname><given-names>A</given-names></name>. <article-title>Explaining risks: turning numerical data into meaningful pictures.</article-title>
<source>BMJ</source>
<year>2002</year>;<volume>324</volume>(<issue>7341</issue>):<fpage>827</fpage>&#x02013;<lpage>830</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.324.7341.827</pub-id>.<pub-id pub-id-type="pmid">11934777</pub-id></mixed-citation></ref><ref id="R70"><label>70.</label><mixed-citation publication-type="journal"><name><surname>Galesic</surname><given-names>M</given-names></name>, <name><surname>Gigerenzer</surname><given-names>G</given-names></name>, <name><surname>Straubinger</surname><given-names>N</given-names></name>. <article-title>Natural frequencies help older adults and people with low numeracy to evaluate medical screening tests.</article-title>
<source>Med Decis Making</source>
<year>2009</year>;<volume>29</volume>(<issue>3</issue>):<fpage>368</fpage>&#x02013;<lpage>371</lpage>. <pub-id pub-id-type="doi">10.1177/0272989X08329463</pub-id>.<pub-id pub-id-type="pmid">19129155</pub-id></mixed-citation></ref><ref id="R71"><label>71.</label><mixed-citation publication-type="journal"><name><surname>Garcia-Retamero</surname><given-names>R</given-names></name>, <name><surname>Galesic</surname><given-names>M</given-names></name>. <article-title>Communicating treatment risk reduction to people with low numeracy skills: a cross-cultural comparison.</article-title>
<source>Am J Public Health</source>
<year>2009</year>;<volume>99</volume>(<issue>12</issue>):<fpage>2196</fpage>&#x02013;<lpage>2202</lpage>. <pub-id pub-id-type="doi">10.2105/AJPH.2009.160234</pub-id>.<pub-id pub-id-type="pmid">19833983</pub-id></mixed-citation></ref><ref id="R72"><label>72.</label><mixed-citation publication-type="journal"><name><surname>Garcia-Retamero</surname><given-names>R</given-names></name>, <name><surname>Galesic</surname><given-names>M</given-names></name>, <name><surname>Gigerenzer</surname><given-names>G</given-names></name>. <article-title>Do icon arrays help reduce denominator neglect?</article-title>
<source>Med Decis Making</source>
<year>2010</year>;<volume>30</volume>(<issue>6</issue>):<fpage>672</fpage>&#x02013;<lpage>684</lpage>. <pub-id pub-id-type="doi">10.1177/0272989X10369000</pub-id>.<pub-id pub-id-type="pmid">20484088</pub-id></mixed-citation></ref><ref id="R73"><label>73.</label><mixed-citation publication-type="journal"><name><surname>Gigerenzer</surname><given-names>G</given-names></name>, <name><surname>Edwards</surname><given-names>A</given-names></name>. <article-title>Simple tools for understanding risks: from innumeracy to insight.</article-title>
<source>BMJ</source>
<year>2003</year>;<volume>327</volume>(<issue>7417</issue>):<fpage>741</fpage>&#x02013;<lpage>744</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.327.7417.741</pub-id>.<pub-id pub-id-type="pmid">14512488</pub-id></mixed-citation></ref><ref id="R74"><label>74.</label><mixed-citation publication-type="journal"><name><surname>Knapp</surname><given-names>P</given-names></name>, <name><surname>Gardner</surname><given-names>PH</given-names></name>, <name><surname>Raynor</surname><given-names>DK</given-names></name>, <name><surname>Woolf</surname><given-names>E</given-names></name>, <name><surname>McMillan</surname><given-names>B</given-names></name>. <article-title>Perceived risk of tamoxifen side effects: a study of the use of absolute frequencies or frequency bands, with or without verbal descriptors.</article-title>
<source>Patient Educ Couns</source>
<year>2010</year>;<volume>79</volume>(<issue>2</issue>):<fpage>267</fpage>&#x02013;<lpage>271</lpage>. <pub-id pub-id-type="doi">10.1016/j.pec.2009.10.002</pub-id>.<pub-id pub-id-type="pmid">19896321</pub-id></mixed-citation></ref><ref id="R75"><label>75.</label><mixed-citation publication-type="journal"><name><surname>Kurz-Milcke</surname><given-names>E</given-names></name>, <name><surname>Gigerenzer</surname><given-names>G</given-names></name>, <name><surname>Martignon</surname><given-names>L</given-names></name>. <article-title>Transparency in risk communication: graphical and analog tools.</article-title>
<source>Ann N Y Acad Sci</source>
<year>2008</year>;<volume>1128</volume>:<fpage>18</fpage>&#x02013;<lpage>28</lpage>. <pub-id pub-id-type="doi">10.1196/annals.1399.004</pub-id>.<pub-id pub-id-type="pmid">18469211</pub-id></mixed-citation></ref><ref id="R76"><label>76.</label><mixed-citation publication-type="journal"><name><surname>Lipkus</surname><given-names>IM</given-names></name>. <article-title>Numeric, verbal, and visual formats of conveying health risks: suggested best practices and future recommendations.</article-title>
<source>Med Decis Making</source>
<year>2007</year>;<volume>27</volume>(<issue>5</issue>):<fpage>696</fpage>&#x02013;<lpage>713</lpage>. <pub-id pub-id-type="doi">10.1177/0272989X07307271</pub-id>.<pub-id pub-id-type="pmid">17873259</pub-id></mixed-citation></ref><ref id="R77"><label>77.</label><mixed-citation publication-type="journal"><name><surname>Paling</surname><given-names>J</given-names></name>
<article-title>Strategies to help patients understand risks.</article-title>
<source>BMJ</source>
<year>2003</year>;<volume>327</volume> (<issue>7417</issue>):<fpage>745</fpage>&#x02013;<lpage>748</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.327.7417.745</pub-id>.<pub-id pub-id-type="pmid">14512489</pub-id></mixed-citation></ref><ref id="R78"><label>78.</label><mixed-citation publication-type="journal"><name><surname>Skolbekken</surname><given-names>JA</given-names></name>. <article-title>Communicating the risk reduction achieved by cholesterol reducing drugs.</article-title>
<source>BMJ</source>
<year>1998</year>;<volume>316</volume>(<issue>7149</issue>):<fpage>1956</fpage>&#x02013;<lpage>1958</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.316.7149.1956</pub-id>.<pub-id pub-id-type="pmid">9641937</pub-id></mixed-citation></ref><ref id="R79"><label>79.</label><mixed-citation publication-type="journal"><name><surname>Visschers</surname><given-names>VH</given-names></name>, <name><surname>Meertens</surname><given-names>RM</given-names></name>, <name><surname>Passchier</surname><given-names>WW</given-names></name>, <name><surname>de Vries</surname><given-names>NN</given-names></name>. <article-title>Probability information in risk communication: a review of the research literature.</article-title>
<source>Risk Anal</source>
<year>2009</year>;<volume>29</volume>(<issue>2</issue>):<fpage>267</fpage>&#x02013;<lpage>287</lpage>. <pub-id pub-id-type="doi">10.1111/j.1539-6924.2008.01137.x</pub-id>.<pub-id pub-id-type="pmid">19000070</pub-id></mixed-citation></ref><ref id="R80"><label>80.</label><mixed-citation publication-type="book"><name><surname>McGee</surname><given-names>J</given-names></name>
<source>Toolkit for making written material cear and effective, CMS Product No. 11476</source>
<publisher-name>Centers for Medicare aned Medicaid Services.</publisher-name>
<year>2010</year>.</mixed-citation></ref><ref id="R81"><label>81.</label><mixed-citation publication-type="journal"><name><surname>Peters</surname><given-names>E</given-names></name>, <name><surname>Dieckmann</surname><given-names>N</given-names></name>, <name><surname>Dixon</surname><given-names>A</given-names></name>, <name><surname>Hibbard</surname><given-names>JH</given-names></name>, <name><surname>Mertz</surname><given-names>CK</given-names></name>. <article-title>Less is more in presenting quality information to consumers.</article-title>
<source>Med Care Res Rev</source>
<year>2007</year>;<volume>64</volume>(<issue>2</issue>):<fpage>169</fpage>&#x02013;<lpage>190</lpage>. <pub-id pub-id-type="doi">10.1177/10775587070640020301</pub-id>.<pub-id pub-id-type="pmid">17406019</pub-id></mixed-citation></ref><ref id="R82"><label>82.</label><mixed-citation publication-type="journal"><name><surname>Berry</surname><given-names>DC</given-names></name>, <name><surname>Michas</surname><given-names>IC</given-names></name>, <name><surname>Rosis</surname><given-names>Fd</given-names></name>
<article-title>Evaluating explanations about drug prescriptions: effects of varying the nature of information about side effects and its relative position in explanations.</article-title>
<source>Psychol Health</source>
<year>1998</year>;<volume>13</volume>(<issue>5</issue>):<fpage>767</fpage>&#x02013;<lpage>784</lpage>. <pub-id pub-id-type="doi">10.1080/08870449808407431</pub-id>.</mixed-citation></ref><ref id="R83"><label>83.</label><mixed-citation publication-type="journal"><name><surname>Zapata</surname><given-names>LB</given-names></name>, <name><surname>Tregear</surname><given-names>SJ</given-names></name>, <name><surname>Curtis</surname><given-names>KM</given-names></name>, <etal/>
<article-title>Impact of contraceptive counseling in clinical settings: a systematic review.</article-title>
<source>Am J Prev Med</source>
<year>2015</year>;<volume>49</volume>(<issue>2</issue>): <fpage>(suppl) S31</fpage>&#x02013;<lpage>S45</lpage>. <pub-id pub-id-type="doi">10.1016/j.amepre.2015.03.023</pub-id>.</mixed-citation></ref><ref id="R84"><label>84.</label><mixed-citation publication-type="journal"><name><surname>Belcher</surname><given-names>L</given-names></name>, <name><surname>Kalichman</surname><given-names>S</given-names></name>, <name><surname>Topping</surname><given-names>M</given-names></name>, <etal/>
<article-title>A randomized trial of a brief HIV risk reduction counseling intervention for women.</article-title>
<source>J Consult Clin Psychol</source>
<year>1998</year>;<volume>66</volume>(<issue>5</issue>):<fpage>856</fpage>&#x02013;<lpage>861</lpage>. <pub-id pub-id-type="doi">10.1037/0022-006X.66.5.856</pub-id>.<pub-id pub-id-type="pmid">9803706</pub-id></mixed-citation></ref><ref id="R85"><label>85.</label><mixed-citation publication-type="journal"><name><surname>Eldridge</surname><given-names>GD</given-names></name>, <name><surname>St Lawrence</surname><given-names>JS</given-names></name>, <name><surname>Little</surname><given-names>CE</given-names></name>, <etal/>
<article-title>Evaluation of the HIV risk reduction intervention for women entering inpatient substance abuse treatment.</article-title>
<source>AIDS Educ Prev</source>
<year>1997</year>;<volume>9</volume>(<issue>1</issue>):<fpage>62</fpage>&#x02013;<lpage>76</lpage>
<comment>(suppl).</comment><pub-id pub-id-type="pmid">9083599</pub-id></mixed-citation></ref><ref id="R86"><label>86.</label><mixed-citation publication-type="book"><name><surname>Jaccard</surname><given-names>J</given-names></name>
<source>Unlocking the Contraceptive Conundrum</source>
<publisher-loc>Washington, DC</publisher-loc>: <publisher-name>The National Campaign to Prevent Teen and Unplanned Pregnancy</publisher-name>, <year>2009</year>.</mixed-citation></ref><ref id="R87"><label>87.</label><mixed-citation publication-type="book"><name><surname>Berkman</surname><given-names>ND</given-names></name>, <name><surname>Sheridan</surname><given-names>SL</given-names></name>, <name><surname>Donahue</surname><given-names>KE</given-names></name>, <etal/>
<source>Health Literacy Interventions and Outcomes: An Updated Systematic Review</source>
<publisher-loc>Rockville, MD</publisher-loc>: <publisher-name>Agency for Healthcare Research and Quality, 2011 Evidence Report/Technology Assesment No. 199. AHRQ Publication Number</publisher-name>
<fpage>11</fpage>&#x02013;<lpage>E006</lpage>.</mixed-citation></ref><ref id="R88"><label>88.</label><mixed-citation publication-type="journal"><name><surname>Schillinger</surname><given-names>D</given-names></name>, <name><surname>Piette</surname><given-names>J</given-names></name>, <name><surname>Grumbach</surname><given-names>K</given-names></name>, <etal/>
<article-title>Closing the loop: physician communication with diabetic patients who have low health literacy.</article-title>
<source>Arch Intern Med</source>
<year>2003</year>;<volume>163</volume>(<issue>1</issue>):<fpage>83</fpage>&#x02013;<lpage>90</lpage>. <pub-id pub-id-type="doi">10.1001/archinte.163.1.83</pub-id>.<pub-id pub-id-type="pmid">12523921</pub-id></mixed-citation></ref><ref id="R89"><label>89.</label><mixed-citation publication-type="journal"><name><surname>McMahon</surname><given-names>SR</given-names></name>, <name><surname>Rimsza</surname><given-names>ME</given-names></name>, <name><surname>Bay</surname><given-names>RC</given-names></name>. <article-title>Parents can dose liquid medication accurately.</article-title>
<source>Pediatrics</source>
<year>1997</year>;<volume>100</volume>(<issue>3, pt 1</issue>):<fpage>330</fpage>&#x02013;<lpage>333</lpage>. <pub-id pub-id-type="doi">10.1542/peds.100.3.330</pub-id>.<pub-id pub-id-type="pmid">9282701</pub-id></mixed-citation></ref><ref id="R90"><label>90.</label><mixed-citation publication-type="journal"><name><surname>Garbers</surname><given-names>S</given-names></name>, <name><surname>Haines-Stephan</surname><given-names>J</given-names></name>, <name><surname>Lipton</surname><given-names>Y</given-names></name>, <name><surname>Meserve</surname><given-names>A</given-names></name>, <name><surname>Spieler</surname><given-names>L</given-names></name>, <name><surname>Chiasson</surname><given-names>MA</given-names></name>. <article-title>Continuation of copper-containing intrauterine devices at 6 months.</article-title>
<source>Contraception</source>
<year>2013</year>;<volume>87</volume>(<issue>1</issue>):<fpage>101</fpage>&#x02013;<lpage>106</lpage>. <pub-id pub-id-type="doi">10.1016/j.contraception.2012.09.013</pub-id>.<pub-id pub-id-type="pmid">23083530</pub-id></mixed-citation></ref><ref id="R91"><label>91.</label><mixed-citation publication-type="journal"><name><surname>Dehlendorf</surname><given-names>C</given-names></name>, <name><surname>Fitzpatrick</surname><given-names>J</given-names></name>, <name><surname>Steinauer</surname><given-names>J</given-names></name>, <etal/>
<article-title>Development and field testing of a decision support tool to facilitate shared decision making in contraceptive counseling.</article-title>
<source>Patient Educ Couns</source>
<year>2017</year>;<volume>100</volume>(<issue>7</issue>):<fpage>1374</fpage>&#x02013;<lpage>1381</lpage>. <pub-id pub-id-type="doi">10.1016/j.pec.2017.02.009</pub-id>.<pub-id pub-id-type="pmid">28237522</pub-id></mixed-citation></ref><ref id="R92"><label>92.</label><mixed-citation publication-type="journal"><name><surname>Koo</surname><given-names>HP</given-names></name>, <name><surname>Wilson</surname><given-names>EK</given-names></name>, <name><surname>Minnis</surname><given-names>AM</given-names></name>. <article-title>A computerized family planning counseling aid: a pilot study evaluation of smart choices.</article-title>
<source>Perspect Sex Reprod Health</source>
<year>2017</year>;<volume>49</volume>(<issue>1</issue>):<fpage>45</fpage>&#x02013;<lpage>53</lpage>. <pub-id pub-id-type="doi">10.1363/psrh.12016</pub-id>.<pub-id pub-id-type="pmid">28222240</pub-id></mixed-citation></ref></ref-list></back><floats-group><fig position="float" id="F1"><label>Figure 1.</label><caption><title>Analytic framework for systematic review of impact of contraceptive education.</title><p id="P49">KQ, key question.</p></caption><graphic xlink:href="nihms-1921294-f0001" position="float"/></fig><fig position="float" id="F2"><label>Figure 2.</label><caption><p id="P50">Flow diagram&#x02014;process of identifying studies included.</p></caption><graphic xlink:href="nihms-1921294-f0002" position="float"/></fig><fig position="float" id="F3"><label>Figure 3.</label><caption><title>Summary of evidence from systematic review on contraceptive education.</title><p id="P51"><sup>a</sup>Includes decision aids, computer games, Facebook page, and smart phone apps.</p><p id="P52"><sup>b</sup>Materials provided or read as a script.</p><p id="P53"><sup>c</sup>Interventions described in Kirby et al. 1989<sup><xref rid="R49" ref-type="bibr">49</xref></sup>; Paperny and Starn 1989<sup><xref rid="R54" ref-type="bibr">54</xref></sup>; Reis and Tymchyshyn 1992<sup><xref rid="R56" ref-type="bibr">56</xref></sup>; O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>; Smith and Whitfield 1995<sup><xref rid="R59" ref-type="bibr">59</xref></sup>; Deijen and Kornaat 1997<sup><xref rid="R46" ref-type="bibr">46</xref></sup>; Little 1998,<sup><xref rid="R44" ref-type="bibr">44</xref></sup> 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup>; DeLamater et al. 2000<sup><xref rid="R47" ref-type="bibr">47</xref></sup>; Lindenberg et al. 2002<sup><xref rid="R50" ref-type="bibr">50</xref></sup>; Johnson et al. 2003<sup><xref rid="R48" ref-type="bibr">48</xref></sup>; Mason et al. 2003<sup><xref rid="R51" ref-type="bibr">51</xref></sup>; Steiner et al. 2003<sup><xref rid="R60" ref-type="bibr">60</xref></sup>; Roberto et al. 2007<sup><xref rid="R57" ref-type="bibr">57</xref></sup>; Schwarz et al. 2008<sup><xref rid="R58" ref-type="bibr">58</xref></sup>; Castano et al. 2012<sup><xref rid="R25" ref-type="bibr">25</xref></sup>; Hall et al. 2013,<sup><xref rid="R32" ref-type="bibr">32</xref></sup> 2014<sup><xref rid="R42" ref-type="bibr">42</xref></sup>; Garbers et al. 2012<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref></sup>; Vogt and Schaefer 2012<sup><xref rid="R41" ref-type="bibr">41</xref></sup>; Schwarz et al. 2013<sup><xref rid="R38" ref-type="bibr">38</xref></sup>; Gilliam et al. 2014<sup><xref rid="R31" ref-type="bibr">31</xref></sup>; Kofinas et al. 2014<sup><xref rid="R33" ref-type="bibr">33</xref></sup>; Davidson et al. 2015<sup><xref rid="R26" ref-type="bibr">26</xref></sup>; Garbers et al. 2015<sup><xref rid="R28" ref-type="bibr">28</xref></sup>; and Sridhar et al. 2015.<sup><xref rid="R40" ref-type="bibr">40</xref></sup></p><p id="P54"><sup>d</sup>Interventions described in: O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>; Little et al. 1998,<sup><xref rid="R44" ref-type="bibr">44</xref></sup> 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup>; Chewning et al. 1999<sup><xref rid="R45" ref-type="bibr">45</xref></sup>; DeLamater et al. 2000<sup><xref rid="R47" ref-type="bibr">47</xref></sup>; Pedrazzini et al. 2000<sup><xref rid="R55" ref-type="bibr">55</xref></sup>; Whitaker et al. 2010<sup><xref rid="R61" ref-type="bibr">61</xref></sup>; Ragland et al. 2011<sup><xref rid="R36" ref-type="bibr">36</xref></sup>; Garbers et al. 2012<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R30" ref-type="bibr">30</xref></sup>; Schwarz et al. 2014<sup><xref rid="R39" ref-type="bibr">39</xref></sup>; Lee et al. 2015<sup><xref rid="R34" ref-type="bibr">34</xref></sup>; Ragland et al. 2015<sup><xref rid="R37" ref-type="bibr">37</xref></sup>; de Reilhac et al. 2016<sup><xref rid="R27" ref-type="bibr">27</xref></sup>; and Michie et al. 2016.<sup><xref rid="R35" ref-type="bibr">35</xref></sup></p><p id="P55"><sup>e</sup>Interventions described in: Kirby et al. 1989<sup><xref rid="R49" ref-type="bibr">49</xref></sup>; Paperny and Starn 1989<sup><xref rid="R54" ref-type="bibr">54</xref></sup>; Reis and Tymchyshyn 1992<sup><xref rid="R56" ref-type="bibr">56</xref></sup>; O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>; Smith and Whitfield 1995<sup><xref rid="R59" ref-type="bibr">59</xref></sup>; Deijen and Kornaat 1997<sup><xref rid="R46" ref-type="bibr">46</xref></sup>; Little 1998,<sup><xref rid="R44" ref-type="bibr">44</xref></sup> 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup>; DeLamater et al. 2000<sup><xref rid="R47" ref-type="bibr">47</xref></sup>; Lindenberg et al. 2002<sup><xref rid="R50" ref-type="bibr">50</xref></sup>; Mason et al. 2003<sup><xref rid="R51" ref-type="bibr">51</xref></sup>; Steiner et al. 2003<sup><xref rid="R60" ref-type="bibr">60</xref></sup>; Roberto et al. 2007<sup><xref rid="R57" ref-type="bibr">57</xref></sup>; Schwarz et al. 2008<sup><xref rid="R58" ref-type="bibr">58</xref></sup>; Castano et al. 2012<sup><xref rid="R25" ref-type="bibr">25</xref></sup>; Hall et al. 2013,<sup><xref rid="R32" ref-type="bibr">32</xref></sup> 2014<sup><xref rid="R42" ref-type="bibr">42</xref></sup>; Vogt and Schaefer 2012<sup><xref rid="R41" ref-type="bibr">41</xref></sup>; Schwarz et al. 2013<sup><xref rid="R38" ref-type="bibr">38</xref></sup>; Gilliam et al. 2014<sup><xref rid="R31" ref-type="bibr">31</xref></sup>; Kofinas et al. 2014<sup><xref rid="R33" ref-type="bibr">33</xref></sup>; Garbers et al. 2015<sup><xref rid="R28" ref-type="bibr">28</xref></sup>; and Sridhar et al. 2015.<sup><xref rid="R40" ref-type="bibr">40</xref></sup></p><p id="P56"><sup>f</sup>Interventions described in O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>; Little et al. 1998,<sup><xref rid="R44" ref-type="bibr">44</xref></sup> 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup>; Chewning et al. 1999<sup><xref rid="R45" ref-type="bibr">45</xref></sup>; DeLamater et al. 2000<sup><xref rid="R47" ref-type="bibr">47</xref></sup>; Pedrazzini et al. 2000<sup><xref rid="R55" ref-type="bibr">55</xref></sup>; Ragland et al. 2011<sup><xref rid="R36" ref-type="bibr">36</xref></sup>; Schwarz et al. 2014<sup><xref rid="R39" ref-type="bibr">39</xref></sup>; Lee et al. 2015<sup><xref rid="R34" ref-type="bibr">34</xref></sup>; Ragland et al. 2015<sup><xref rid="R37" ref-type="bibr">37</xref></sup>; de Reilhac et al. 2016<sup><xref rid="R27" ref-type="bibr">27</xref></sup>; and Michie et al. 2016.<sup><xref rid="R35" ref-type="bibr">35</xref></sup></p><p id="P57"><sup>g</sup>Interventions described in Johnson et al. 2003<sup><xref rid="R48" ref-type="bibr">48</xref></sup>; Mason et al. 2003<sup><xref rid="R51" ref-type="bibr">51</xref></sup>; Steiner et al. 2003<sup><xref rid="R60" ref-type="bibr">60</xref></sup>; Kofinas et al. 2014<sup><xref rid="R33" ref-type="bibr">33</xref></sup>; Davidson et al. 2015<sup><xref rid="R26" ref-type="bibr">26</xref></sup>; and Sridhar et al. 2015.<sup><xref rid="R40" ref-type="bibr">40</xref></sup></p><p id="P58"><sup>h</sup>Intervention described in: Schwarz et al. 2014<sup><xref rid="R39" ref-type="bibr">39</xref></sup>; Lee et al. 2015.<sup><xref rid="R34" ref-type="bibr">34</xref></sup></p><p id="P59"><sup>i</sup>Indicates intervention had a marginally significant effect on this outcome (0.05&#x0003c;<italic toggle="yes">p</italic>&#x0003c;0.1).</p><p id="P60"><sup>j</sup>Interventions described in Deijen and Kornaat 1997<sup><xref rid="R46" ref-type="bibr">46</xref></sup>; Schwarz et al. 2008<sup><xref rid="R58" ref-type="bibr">58</xref></sup>; Vogt and Schaefer 2012<sup><xref rid="R41" ref-type="bibr">41</xref></sup>; and Kofinas et al. 2014.<sup><xref rid="R33" ref-type="bibr">33</xref></sup></p><p id="P61"><sup>k</sup>Intervention described in Whitaker et al. 2010.<sup><xref rid="R61" ref-type="bibr">61</xref></sup></p><p id="P62"><sup>l</sup>Interventions described in Garbers et al. 2012<sup><xref rid="R30" ref-type="bibr">30</xref></sup>; Gilliam et al. 2014<sup><xref rid="R31" ref-type="bibr">31</xref></sup>; and Sridhar et al. 2015.<sup><xref rid="R40" ref-type="bibr">40</xref></sup></p><p id="P63"><sup>m</sup>Intervention described in Garbers et al. 2012.<sup><xref rid="R30" ref-type="bibr">30</xref></sup></p><p id="P64"><sup>n</sup>Interaction with educational level described in Little et al. 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup> and Hall et al. 2013.<sup><xref rid="R32" ref-type="bibr">32</xref></sup></p><p id="P65"><sup>o</sup>Interaction with educational level described in Little et al. 2001<sup><xref rid="R43" ref-type="bibr">43</xref></sup> and Regland et al. 2011.</p><p id="P66"><sup>p</sup>Interventions described in Kirby et al. 1989<sup><xref rid="R49" ref-type="bibr">49</xref></sup>; O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup>; Vogt and Schaefer 2012<sup><xref rid="R41" ref-type="bibr">41</xref></sup>; and Garbers et al. 2015.<sup><xref rid="R28" ref-type="bibr">28</xref></sup></p><p id="P67"><sup>q</sup>Interventions described in O&#x02019;Donnell et al. 1995<sup><xref rid="R52" ref-type="bibr">52</xref>,<xref rid="R53" ref-type="bibr">53</xref></sup> and Michie et al. 2016.<sup><xref rid="R35" ref-type="bibr">35</xref></sup></p><p id="P68"><sup>r</sup>Significant increase over baseline, but significance of increase relative to controls not reported.</p><p id="P69"><sup>s</sup>Interventions described in Kirby et al. 1989<sup><xref rid="R49" ref-type="bibr">49</xref></sup>; DeLamater et al. 2000<sup><xref rid="R47" ref-type="bibr">47</xref></sup>; and Schwarz et al. 2008.<sup><xref rid="R58" ref-type="bibr">58</xref></sup></p><p id="P70"><sup>t</sup>Intervention described in DeLamater et al. 2000.<sup><xref rid="R47" ref-type="bibr">47</xref></sup></p><p id="P71"><sup>u</sup>Interventions described in Deijen and Kornaat 1997<sup><xref rid="R46" ref-type="bibr">46</xref></sup>; Garbers et al. 2012<sup><xref rid="R29" ref-type="bibr">29</xref></sup>; and Castano et al. 2012<sup><xref rid="R25" ref-type="bibr">25</xref></sup>; Hall et al. 2013,<sup><xref rid="R32" ref-type="bibr">32</xref></sup> 2014.<sup><xref rid="R42" ref-type="bibr">42</xref></sup></p><p id="P72"><sup>v</sup>Interventions described in Chewning et al. 1999<sup><xref rid="R45" ref-type="bibr">45</xref></sup>; Garbers et al. 2012<sup><xref rid="R29" ref-type="bibr">29</xref></sup>; and Michie et al. 2016.<sup><xref rid="R35" ref-type="bibr">35</xref></sup></p><p id="P73"><sup>w</sup>Intervention described in Schwarz et al. 2008.<sup><xref rid="R58" ref-type="bibr">58</xref></sup></p><p id="P74"><sup>x</sup>Intervention described in Chewning et al. 1999.<sup><xref rid="R45" ref-type="bibr">45</xref></sup></p><p id="P75">KQ, key question.</p></caption><graphic xlink:href="nihms-1921294-f0003" position="float"/></fig><table-wrap position="float" id="T1" orientation="landscape"><label>Table 1.</label><caption><p id="P76">Key Questions for Systematic Review on Impact of Education Interventions</p></caption><table frame="box" rules="groups"><colgroup span="1"><col align="left" valign="middle" span="1"/><col align="left" valign="middle" span="1"/></colgroup><thead><tr><th align="left" valign="bottom" rowspan="1" colspan="1">KQ no.</th><th align="center" valign="bottom" rowspan="1" colspan="1">Question</th></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">1</td><td align="left" valign="top" rowspan="1" colspan="1">Does contraceptive education increase comprehension of risks and benefits of contraceptive choices, including potential side effects, method effectiveness, and correct method use?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">2</td><td align="left" valign="top" rowspan="1" colspan="1">Does contraceptive education increase participation in the decision-making process?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">3</td><td align="left" valign="top" rowspan="1" colspan="1">Does contraceptive education increase satisfaction/comfort with services and decision making?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">4</td><td align="left" valign="top" rowspan="1" colspan="1">Does contraceptive education increase positive attitudes about contraception?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">5</td><td align="left" valign="top" rowspan="1" colspan="1">Does contraceptive education increase selection of more as compared with less effective methods?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">6</td><td align="left" valign="top" rowspan="1" colspan="1">What are the barriers and facilitators for clinics or clients related to the provision or receipt of education?</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">7</td><td align="left" valign="top" rowspan="1" colspan="1">Are there any unintended negative consequences associated with contraceptive education?</td></tr></tbody></table><table-wrap-foot><fn id="TFN1"><p id="P77"><italic toggle="yes">Note</italic>: The key questions are put into context by the analytic framework presented in <xref rid="F1" ref-type="fig">Figure 1</xref>.</p></fn><fn id="TFN2"><p id="P78">KQ, key question.</p></fn></table-wrap-foot></table-wrap></floats-group></article>