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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.3" xml:lang="en" article-type="research-article"><?properties manuscript?><processing-meta base-tagset="archiving" mathml-version="3.0" table-model="xhtml" tagset-family="jats"><restricted-by>pmc</restricted-by></processing-meta><front><journal-meta><journal-id journal-id-type="nlm-journal-id">0373220</journal-id><journal-id journal-id-type="pubmed-jr-id">3582</journal-id><journal-id journal-id-type="nlm-ta">Ergonomics</journal-id><journal-id journal-id-type="iso-abbrev">Ergonomics</journal-id><journal-title-group><journal-title>Ergonomics</journal-title></journal-title-group><issn pub-type="ppub">0014-0139</issn><issn pub-type="epub">1366-5847</issn></journal-meta><article-meta><article-id pub-id-type="pmid">36227226</article-id><article-id pub-id-type="pmc">10130228</article-id><article-id pub-id-type="doi">10.1080/00140139.2022.2136407</article-id><article-id pub-id-type="manuscript">HHSPA1871419</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Comparison of the Observer, Single-Frame Video and Computer Vision Hand Activity Levels</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Radwin</surname><given-names>Robert G.</given-names></name><xref rid="CR1" ref-type="corresp">*</xref><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Hu</surname><given-names>Yu Hen</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Akkas</surname><given-names>Oguz</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Bao</surname><given-names>Stephen</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Harris-Adamson</surname><given-names>Carisa</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>Lin</surname><given-names>Jia-Hua</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Meyers</surname><given-names>Alysha R.</given-names></name><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Rempel</surname><given-names>David</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib></contrib-group><aff id="A1"><label>1</label>University of Wisconsin, Madison, WI, USA</aff><aff id="A2"><label>2</label>SHARP Program, Washington State Department of Labor and Industries, Olympia, WA, USA</aff><aff id="A3"><label>3</label>University of California-San Francisco, San Francisco, CA, USA</aff><aff id="A4"><label>4</label>Division of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, OH, USA</aff><author-notes><corresp id="CR1"><label>*</label>Corresponding Author: Department of Industrial and Systems Engineering, University of Wisconsin-Madison, 1550 Engineering Drive, Madison, WI 53706 USA, <email>rradwin@wisc.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>24</day><month>2</month><year>2023</year></pub-date><pub-date pub-type="ppub"><month>8</month><year>2023</year></pub-date><pub-date pub-type="epub"><day>26</day><month>10</month><year>2022</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>8</month><year>2024</year></pub-date><volume>66</volume><issue>8</issue><fpage>1132</fpage><lpage>1141</lpage><abstract id="ABS1"><p id="P1">Observer, manual single-frame video, and automated computer vision measures of the Hand Activity Level (HAL) were compared. HAL can be measured three ways: 1) observer rating (HAL<sub>O</sub>), 2) calculated from single-frame multimedia video task analysis for measuring frequency (F) and duty cycle (D) (HAL<sub>F</sub>), or 3) from automated computer vision (HAL<sub>C</sub>). This study analyzed videos collected from three prospective cohort studies to ascertain HAL<sub>O</sub>, HAL<sub>F</sub>, and HAL<sub>C</sub> for 419 industrial videos. Although the differences for the three methods were relatively small on average (&#x0003c;1), they were statistically significant (<italic toggle="yes">p</italic>&#x0003c;.001). A difference between the HAL<sub>C</sub> and HAL<sub>F</sub> ratings within &#x000b1;1 point on the HAL scale was the most consistent, where more than two thirds (68%) of all the cases were within that range and had a linear regression through the mean coefficient of 1.03 (<italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.89). The results suggest that the computer vision methodology yields comparable results as single-frame video analysis.</p></abstract><abstract id="ABS2" abstract-type="summary"><title>Practitioner Summary:</title><p id="P2">The ACGIH Hand Activity Level (HAL) was obtained for 419 industrial tasks using three methods: observation, calculated using single-frame video analysis and computer vision. The computer vision methodology produced results that were comparable to single-frame video analysis.</p></abstract><kwd-group><kwd>Hand activity level</kwd><kwd>repetitive motion</kwd><kwd>computer vision</kwd></kwd-group></article-meta></front><body><sec id="S1"><label>1.</label><title>Introduction</title><p id="P3">Numerous methods have been developed for quantifying the risk of upper limb musculoskeletal injuries, including self-reports, observation, video-based single-frame analysis, and direct measurements (<xref rid="R23" ref-type="bibr">Joshi and Deshpande, 2019</xref>). Each technique has advantages and disadvantages (<xref rid="R13" ref-type="bibr">David, 2005</xref>). The hand activity level (HAL) rating is a 10-point visual analog scale based on hand speed and rest pauses, where HAL=0 when the hands are idle most of the time and there are no regular exertions, and HAL=10 when there is rapid steady motion, continuous exertion and difficulty keeping up. The observed HAL rating is recorded as an integer value. Originally introduced by <xref rid="R27" ref-type="bibr">Latko, et al. (1997)</xref>, the HAL rating has been adopted by the American Conference of Governmental Industrial Hygienists (ACGIH) in 2001 Hand Activity Threshold Limit Value<sup>&#x000ae;</sup> (TLV<sup>&#x000ae;</sup>) (ACGIH, 2021).</p><p id="P4">Epidemiological investigations demonstrated significant relationships between the TLV<sup>&#x000ae;</sup> action limit and elbow/forearm tendonitis, carpal tunnel syndrome (CTS) (<xref rid="R16" ref-type="bibr">Franzblau et al., 2005</xref>), and musculoskeletal pain (<xref rid="R35" ref-type="bibr">Werner et al., 2005</xref>). Longitudinal studies of manufacturing workers found that the TLV<sup>&#x000ae;</sup> for HAL was predictive of increased risk for carpal tunnel syndrome (<xref rid="R17" ref-type="bibr">Garg, et al., 2012</xref>, <xref rid="R38" ref-type="bibr">Yung et al., 2019</xref>, <xref rid="R25" ref-type="bibr">Kapellusch et al., 2014a</xref>), predicted increased risk for CTS while controlling for obesity and job strain (<xref rid="R9" ref-type="bibr">Burt, et al., 2013</xref>), and was associated with increased risk for flexor tendon entrapment of the digits (<xref rid="R26" ref-type="bibr">Kapellusch et al., 2014b</xref>).</p><p id="P5">The observational method for ascertaining the HAL rating for a job requires a trained observer viewing workers performing the job on-site or observing a video of the job off-site. <xref rid="R33" ref-type="bibr">Takala, et al. (2010)</xref> recommended the observational HAL rating for general screening purposes. Without training, interobserver reliability is moderate (Kappa = 0.52) but with training, reliability increases (Kappa = 0.70) (<xref rid="R14" ref-type="bibr">Ebersole and Armstrong, 2002</xref>).</p><p id="P6">In addition to observer ratings, the HAL may also be determined from a lookup table (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">T</italic></sub>), which is part of the TLV<sup>&#x000ae;</sup> by measuring exertion frequency (<italic toggle="yes">F</italic>) and percent duty cycle (<italic toggle="yes">D</italic>) where:
<disp-formula id="FD1">
<label>(1)</label>
<mml:math id="M1" display="block"><mml:mi>F</mml:mi><mml:mo>=</mml:mo><mml:mfenced separators="|"><mml:mrow><mml:mfrac><mml:mrow><mml:mi mathvariant="normal">n</mml:mi><mml:mi mathvariant="normal">o</mml:mi><mml:mo>.</mml:mo><mml:mspace width="0.25em"/><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">x</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">o</mml:mi><mml:mi mathvariant="normal">n</mml:mi><mml:mi mathvariant="normal">s</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">x</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">o</mml:mi><mml:mi mathvariant="normal">n</mml:mi><mml:mspace width="0.25em"/><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">m</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mo>+</mml:mo><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">s</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">m</mml:mi><mml:mi mathvariant="normal">e</mml:mi></mml:mrow></mml:mfrac></mml:mrow></mml:mfenced></mml:math>
</disp-formula>
and
<disp-formula id="FD2">
<label>(2)</label>
<mml:math id="M2" display="block"><mml:mi>D</mml:mi><mml:mo>=</mml:mo><mml:mn>100</mml:mn><mml:mfenced separators="|"><mml:mrow><mml:mfrac><mml:mrow><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">x</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">o</mml:mi><mml:mi mathvariant="normal">n</mml:mi><mml:mspace width="0.25em"/><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">m</mml:mi><mml:mi mathvariant="normal">e</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">x</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">o</mml:mi><mml:mi mathvariant="normal">n</mml:mi><mml:mspace width="0.25em"/><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">m</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mo>+</mml:mo><mml:mi mathvariant="normal">r</mml:mi><mml:mi mathvariant="normal">e</mml:mi><mml:mi mathvariant="normal">s</mml:mi><mml:mi mathvariant="normal">t</mml:mi><mml:mspace width="0.25em"/><mml:mi mathvariant="normal">t</mml:mi><mml:mi mathvariant="normal">i</mml:mi><mml:mi mathvariant="normal">m</mml:mi><mml:mi mathvariant="normal">e</mml:mi></mml:mrow></mml:mfrac></mml:mrow></mml:mfenced></mml:math>
</disp-formula>
where exertion times and rest times are totaled within a cycle. Radwin, et al. (2014) developed an equation for estimating HAL based on measurements of F and D using data from <xref rid="R27" ref-type="bibr">Latko, et al. (1997)</xref> to continuously predict HAL values consistent with the TLV<sup>&#x000ae;</sup> look-up table. The equation:
<disp-formula id="FD3">
<label>(3)</label>
<mml:math id="M3" display="block"><mml:mi>H</mml:mi><mml:mi>A</mml:mi><mml:mi>L</mml:mi><mml:mo>=</mml:mo><mml:mn>6</mml:mn><mml:mo>.</mml:mo><mml:mn>56</mml:mn><mml:mrow><mml:mrow><mml:mspace width="0.15em"/><mml:mtext>ln</mml:mtext></mml:mrow><mml:mrow><mml:mspace width="0.15em"/><mml:mi>D</mml:mi></mml:mrow></mml:mrow><mml:mspace width="0.25em"/><mml:mfenced open="[" close="]" separators="|"><mml:mrow><mml:mfrac><mml:mrow><mml:msup><mml:mrow><mml:mi>F</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>.</mml:mo><mml:mn>31</mml:mn></mml:mrow></mml:msup></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>+</mml:mo><mml:mn>3</mml:mn><mml:mo>.</mml:mo><mml:mn>18</mml:mn><mml:mspace width="0.25em"/><mml:msup><mml:mrow><mml:mi>F</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>.</mml:mo><mml:mn>31</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:mfrac></mml:mrow></mml:mfenced></mml:math>
</disp-formula>
can be utilized to directly measure HAL and is also part of the TLV<sup>&#x000ae;</sup>. The direct measurement method is typically applied by using video single-frame analysis.</p><p id="P7">Video single-frame analysis has been used for objectively measuring F and D utilizing software such as multimedia video task analysis (MVTA) by marking the video frames when exertions start and end in a cycle (<xref rid="R37" ref-type="bibr">Yen and Radwin, 1995</xref>). This method has been frequently used for calculating HAL directly from videos (<xref rid="R4" ref-type="bibr">Bao, et al, 2006a</xref>; <xref rid="R9" ref-type="bibr">Burt et al., 2013</xref>; <xref rid="R19" ref-type="bibr">Harris, et al., 2011</xref>). Although the method is objective, it is time intensive, requiring the video to be viewed by an analyst in slow-motion or by single-frame.</p><p id="P8"><xref rid="R5" ref-type="bibr">Bao et al. (2006b)</xref> observed poor correlation between HAL observations, self-reports, and direct measurements and noted several reasons for different ratings, including using different definitions of an exertion. <xref rid="R36" ref-type="bibr">Wurzelbacher, et al. (2010)</xref> compared more than 700 tasks for 484 workers and found that while correlated (Spearman rank = 0.49), the agreement between HAL ratings (within &#x000b1;1point) from observations and calculated from videos was 61%. An objective automated method for measuring HAL is therefore desirable, especially for routine practice in industry.</p><p id="P9"><xref rid="R10" ref-type="bibr">Chen et al. (2013)</xref> developed an automated method for measuring HAL using a cross correlation-based template matching algorithm to track the motion trajectory of a selected region of interest (ROI) over successive video frames. The authors demonstrated that HAL can be calculated by automatically measuring <italic toggle="yes">F</italic> and <italic toggle="yes">D</italic> from hand displacement, speed and acceleration signals.</p><p id="P10">To further pursue the above goal, <xref rid="R1" ref-type="bibr">Akkas et al. (2015)</xref> developed an equation to measure HAL directly from RMS hand speed (<italic toggle="yes">S</italic>) and <italic toggle="yes">D</italic> since the HAL scale is anchored against the speed of hand motion/exertions and rest pauses. Furthermore, measuring <italic toggle="yes">F</italic> of repetitive motion is more challenging when the motion becomes more complex, such as when exertions and motions coincide. The equation was:
<disp-formula id="FD4">
<label>(4)</label>
<mml:math id="M4" display="block"><mml:mi>H</mml:mi><mml:mi>A</mml:mi><mml:mi>L</mml:mi><mml:mo>=</mml:mo><mml:mn>10</mml:mn><mml:mspace width="0.25em"/><mml:mfenced open="[" close="]" separators="|"><mml:mrow><mml:mfrac><mml:mrow><mml:msup><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mo>-</mml:mo><mml:mn>15</mml:mn><mml:mo>.</mml:mo><mml:mn>87</mml:mn><mml:mo>+</mml:mo><mml:mn>0</mml:mn><mml:mo>.</mml:mo><mml:mn>02</mml:mn><mml:mi mathvariant="normal">D</mml:mi><mml:mo>+</mml:mo><mml:mn>2</mml:mn><mml:mo>.</mml:mo><mml:mn>25</mml:mn><mml:mrow><mml:mrow><mml:mspace width="0.15em"/><mml:mtext>ln</mml:mtext></mml:mrow><mml:mrow><mml:mspace width="0.15em"/><mml:mi>S</mml:mi></mml:mrow></mml:mrow></mml:mrow></mml:msup></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>+</mml:mo><mml:msup><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mo>-</mml:mo><mml:mn>15</mml:mn><mml:mo>.</mml:mo><mml:mn>87</mml:mn><mml:mo>+</mml:mo><mml:mn>0</mml:mn><mml:mo>.</mml:mo><mml:mn>02</mml:mn><mml:mi mathvariant="normal">D</mml:mi><mml:mo>+</mml:mo><mml:mn>2</mml:mn><mml:mo>.</mml:mo><mml:mn>25</mml:mn><mml:mrow><mml:mrow><mml:mspace width="0.15em"/><mml:mtext>ln</mml:mtext></mml:mrow><mml:mspace width="0.15em"/><mml:mrow><mml:mi>S</mml:mi></mml:mrow></mml:mrow></mml:mrow></mml:msup></mml:mrow></mml:mfrac></mml:mrow></mml:mfenced></mml:math>
</disp-formula></p><p id="P11">Finally, to measure <italic toggle="yes">D</italic> from single video cameras, <xref rid="R2" ref-type="bibr">Akkas et al. (2016)</xref> developed machine learning algorithms for laboratory simulations and tested them for real factory repetitive motion tasks to determine how accurately the algorithms work for different tasks (<xref rid="R3" ref-type="bibr">Akkas et al., 2017</xref>). A Feature Vector Training (FVT) algorithm was trained using corresponding phases (i.e. exertion and rest) based on the first cycle of each video clip. The first cycle of each video that were manually annotated using MVTA were inputted for the first cycle exertion and rest elemental times were used to train a k-nearest neighbor (kNN) classifier as the state estimator. The algorithm used k=1 since only one cycle was used for training. Subsequent exertion and rest states for the remaining nine cycles were automatically classified by the algorithm.</p><p id="P12">In the current study we compare the HAL values calculated using the three different methods; HAL based on an observer ratings (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">O</italic></sub>), HAL calculated from single-frame-video analysis for measuring F and D (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">F</italic></sub>) (<xref rid="R30" ref-type="bibr">Radwin et al., 2015</xref>), and HAL calculated using computer vision marker-less tracking for measuring hand speed and the kinematic properties from the hand tracking signal (i.e. location, speed and acceleration) to identify patterns when an exertion was made to measure D (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">C</italic></sub>) (<xref rid="R1" ref-type="bibr">Akkas et al., 2015</xref>; <xref rid="R2" ref-type="bibr">2016</xref>). Moreover, we provide recommendations based on these analyses for obtaining more consistent measurements of HAL.</p></sec><sec id="S2"><label>2.</label><title>Methods</title><sec id="S3"><label>2.1.</label><title>Pooled data from the NIOSH, SHARP and UCSF upper extremity consortium studies</title><p id="P13">This study considers exposure data from three sources, including prospective studies performed by the National Institute for Occupational Safety and Health (NIOSH), the Washington State Department of Labor and Industries Safety &#x00026; Health Assessment &#x00026; Research for Prevention Program (SHARP) and the University of California-San Francisco (UCSF). These data were part of a collaborative research program, the Upper Limb Musculoskeletal Disorder Consortium (ULMSDC), that included prospective cohort studies conducted by NIOSH, six universities and one state agency (<xref rid="R7" ref-type="bibr">Bao et al., 2015</xref>; <xref rid="R20" ref-type="bibr">Harris-Adamson et. al., 2013a</xref>, <xref rid="R21" ref-type="bibr">2013b</xref>; <xref rid="R22" ref-type="bibr">Harris-Adamson et. al., 2014</xref>; <xref rid="R24" ref-type="bibr">Kappellusch et al., 2013</xref>, 2014; <xref rid="R15" ref-type="bibr">Fan et al., 2015</xref>). The original pooled data for the three research studies had 1649 workers from 16 industries from a variety of industries such as Medical and Surgical Hospitals, Concrete Products, and Manufacturing. Each study collected exposure data independently using observation, direct instrumentation measurement, single-frame video analysis, or self-reports. NIOSH data were collected for 483 workers from three employers in three states. SHARP had 719 workers, from 13 different sites in Washington State. UCSF had 447 participants from 4 sites. All the above studies collected force, repetition, posture, and vibration exposure variables.</p></sec><sec id="S4"><label>2.2.</label><title>Ethical Statement</title><p id="P14">Ethical approval was obtained from the appropriate local ethics committee or Institutional Review Board (University of Wisconsin-Madison Federal Wide Assurance no. #FWA00005399), protocol number 2016-0297-CR006, and that informed consent has been obtained.</p></sec><sec id="S5"><label>2.3.</label><title>Inclusion criteria for automated analysis</title><p id="P15">While we report the number of workers in the prospective study, each worker had a job that may involve one or more tasks. This study involved individual video clips and did not consider which operators were included or excluded. Videos were created for baseline or follow-up data. No distinction was made if a particular video associated with a unique task was recorded during a baseline or during a subsequent visit.</p><p id="P16">All three studies provided videos of every task for the current study, as defined by Bao et al. (2009). Videos satisfying the pre-determined inclusion criteria for automated analysis, described below, were used in the hand tracking algorithm and extract kinematic data including velocity and acceleration.</p><p id="P17">To make an objective video selection, we defined inclusion criteria for computer vision analysis suitability. All videos provided by the ULMSDC prospective studies were originally produced in or converted to an MP4 format and had an accompanying coded MVTA data file. Because the videos were created for a different purpose, not all videos were suitable for computer vision analysis. Examples of non-suitable videos included instances of occlusion of the hand for much of the video by other body parts, tools or other workers, or non-stable camera recording which introduced an artificial signal when the hand was tracked. In the current study, work is comprised of a series of <italic toggle="yes">tasks</italic>. A <italic toggle="yes">job J</italic><sub><italic toggle="yes">i</italic></sub> could consist of primarily one or more tasks <italic toggle="yes">T</italic><sub><italic toggle="yes">j</italic></sub> &#x02208; <italic toggle="yes">J</italic><sub><italic toggle="yes">i</italic></sub> performed throughout the workday. A task may have occurred one or more times, as part of a job. In general, tasks are defined as typically having a specific goal, such as loading a machine, operating a tool , or lifting materials, and are specific to an industry or business, and their associated products or services. A cycle is a series of motions or exertions that are performed repeatedly. All the jobs studied had repetitive cycles where the task performed was repeated. The criteria for inclusion were videos containing at least five contiguous cycles with limited camera motions.</p><p id="P18">Videos were excluded if breaks were taken that were outside the primary task or the hand location was unable to be determined due to an obstructed view of the hand and arm. The inclusion test determined that 1,098 videos were initially deemed unsuitable. An additional 136 videos were subsequently excluded because they could not be tracked using the computer vison software because of extraneous body movements, occlusions, missing activity in the video, or they depicted insignificant exertion levels for determining HAL (i.e., HAL=0). A total of 419 videos remained suitable for computer vision analysis.</p><p id="P19">HAL estimates were all made at the task level. Exposures were based on a trained analyst&#x02019;s observation of each participant performing his or her usual work tasks augmented with interviews of workers and their supervisors. Frequency and duty cycle was based on detailed time studies of task-level videos.</p></sec><sec id="S6"><label>2.4.</label><title>Observer HAL (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">O</italic></sub>)</title><p id="P20">Each video was viewed by the same trained analyst who rated <italic toggle="yes">HAL</italic><sub><italic toggle="yes">o</italic></sub> for the dominant hand according to the visual-analog scale in the TLV (American Conference of Governmental Industrial Hygienists, 2020). The same analyst who conducted the below-mentioned review and re-annotation of the videos, performed the observed HAL ratings but was blinded to the HAL<sub>F</sub> calculated values.</p></sec><sec id="S7"><label>2.5.</label><title>Single-Frame Video Analysis HAL (<italic toggle="yes">HAL</italic><sub><italic toggle="yes">F</italic></sub>)</title><p id="P21">The videos were previously coded for exertion and rest time by multiple analysts from the individual institutions of the ULMSDC. Since the videos were previously coded using MVTA for a different purpose, the single-frame analysis was conducted for the current study using the following definition of exertions. An exertion was defined as a visible hand or forearm muscular effort while grasping an object or applying a force (e.g., hold, manipulate, trigger, push, pull, or handle an object) during task performance, regardless of the force required. Exertions that were less than 10% MVC were excluded and contributed to rest time. Every qualifying exertion was included, even if it was not followed by a pause (e.g., when a sequence of exertions occurred while retaining an object, or when grasp of an object was released and immediately followed by another grasp).</p><p id="P22">A review of the MVTA video data files originally created for the ULMSD Consortium prospective study was conducted for consistency with the definitions of exertions for the current study and when these were not consistent, they were revised. A total of 41 videos were reannotated to be made consistent with the above definitions.</p><p id="P23">The frequency (<italic toggle="yes">F</italic>) for each video was calculated based on <xref rid="FD1" ref-type="disp-formula">Equation 1</xref> as the number of exertions that occurred during the duration of the video clip of the task divided by the duration of the video clip. The duty cycle (<italic toggle="yes">D</italic>) for each video was calculated based on <xref rid="FD2" ref-type="disp-formula">Equation 2</xref> from the total duration of exertions in the clip (i.e. exertion time) and the difference between the duration of the video clip (i.e. total time) minus the exertion time (i.e. rest time). <italic toggle="yes">HAL</italic><sub><italic toggle="yes">F</italic></sub> was calculated using <xref rid="FD3" ref-type="disp-formula">Equation 3</xref>.</p></sec><sec id="S8"><label>2.6.</label><title>Computer Vision HAL (HAL<sub>C</sub>)</title><p id="P24">Custom tracking software (<xref rid="R11" ref-type="bibr">Chen, et al., 2014</xref>) was used for calculating the pixel coordinates of the hand for every video frame. The process for calculating HAL was fully described in <xref rid="R1" ref-type="bibr">Akkas et al. (2015</xref>, <xref rid="R2" ref-type="bibr">2016)</xref>. The analyst indicated the dominant hand and initialized the region of interest (ROI) to track starting from the first frame that captured the most active hand fully (<xref rid="F1" ref-type="fig">Figure 1</xref>). The analyst started the tracking program and manually corrected the tracked location of the hands when the algorithm failed. The dominant hand was tracked, and the hand location was scaled using hand breadth data. After the hand was tracked, the pixel data was calibrated according to the average male or female hand breadth, as described in <xref rid="R2" ref-type="bibr">Akkas et al. (2016)</xref>. Duty cycle was calculated using the kNN classifier algorithm described in <xref rid="R2" ref-type="bibr">Akkas et al. (2016)</xref> based on identifying exertions in the first cycle of the task and then HAL was calculated using <xref rid="FD4" ref-type="disp-formula">Equation 4</xref>.</p></sec><sec id="S9"><label>2.7.</label><title>Statistical Analysis</title><p id="P25">The original HAL scale used observation (<xref rid="R27" ref-type="bibr">Latko, et al., 1997</xref>) and applied a visual analog scale rating for a mono-cycle task, results in an integer value from 0 to 10. A similar convention was used for recording HAL<sub>O</sub> in this study. Since the single-frame (HAL<sub>F</sub>) and computer vision (HAL<sub>C</sub>) estimates were calculated values, they were not rounded to the nearest integer in the statistical analysis, while observed HAL values were measured as integers. Statistical analyses were performed using RStudio statistical software (Version 1.3.1093) and Microsoft Excel (Version 2207).</p><p id="P26">Analysis of variance (ANOVA) was used to test the differences between method (HAL<sub>O</sub>, HAL<sub>F</sub> and HAL<sub>C</sub>). To assess the agreement between HAL methods, we calculated percent agreement within &#x000b1;1-point since it was previously defined as consensus when raters were within a &#x000b1;1-point difference (<xref rid="R27" ref-type="bibr">Latko et al., 1997</xref>). Additionally, we utilized the Bland-Altman analysis to check agreement between the different HAL measures. The Bland-Altman analysis considers the limits of differences between two nonstandard methods to check the agreement between the different HAL measures. The limits of differences were calculated from the means (m) and standard deviations (SD) of differences between two methods. An acceptable difference was considered( &#x000b1;1.96 SD) (<xref rid="R18" ref-type="bibr">Giavarina, 2015</xref>).</p></sec></sec><sec id="S10"><label>3.</label><title>Results</title><p id="P27">The HAL values were statistically different among the three methods (HAL<sub>C</sub>, HAL<sub>F</sub> and HAL<sub>O</sub>) for calculating HAL (<italic toggle="yes">F</italic>(2, 1251)=15.71, <italic toggle="yes">p</italic>&#x0003c;.001), where the videos were treated as a random variable. The contrast between HAL<sub>C</sub> &#x02212; HAL<sub>F</sub> was 0.35, and the 95% Tukey multiple family-wise confidence interval ranged from 0.05 to 0.74 (<italic toggle="yes">p</italic>=.02). The average absolute difference between HAL<sub>C</sub> &#x02212;HAL<sub>F</sub> was 1.20 (SD=0.83, Max=4.89, 95% CI=0.11). The contrasts between HAL<sub>O</sub> &#x02212;HAL<sub>F</sub> was 0.56, and the 95% Tukey multiple family-wise confidence interval was 0.27 to 0.86 (p&#x0003c;.001). The average absolute difference between HAL<sub>O</sub> &#x02212;HAL<sub>F</sub> was 1.31 (SD=1.02, Max=5.75, 95% CI=0.12). There was no statistically significant difference in the contrasts between HAL<sub>C</sub> &#x02212;HAL<sub>O</sub> with an overall difference of &#x02212;0.220, and the 95% Tukey multiple family-wise confidence interval was &#x02212;0.52 to 0.08 (p=.19). The average absolute difference between HAL<sub>C</sub> &#x02212;HAL<sub>O</sub> was 1.38 (SD=1.14, Max=7.16, 95% CI=0.14).</p><p id="P28">Histograms for the differences between HAL<sub>C</sub> &#x02212;HAL<sub>F</sub>, HAL<sub>C</sub> &#x02212;HAL<sub>O</sub>, and HAL<sub>F</sub> &#x02212;HAL<sub>O</sub> are plotted in <xref rid="F2" ref-type="fig">Figure 2</xref>. Since the HAL scale requires an integer value between 0 and 10 (ACGIH, 2021), a difference of one HAL rounded to the nearest integer between &#x02212;1.5 &#x0003c; HAL<sub>C</sub> &#x02212; HAL<sub>F</sub> &#x0003c; 1.5 was observed for 68% (N=284 cases), and between &#x02212;2.0 &#x0003c; HAL<sub>C</sub> &#x02212;HAL<sub>F</sub> &#x0003c; 2.0 was observed for 89% (N=374 cases) of the data, as shown in <xref rid="F2" ref-type="fig">Figure 2A</xref>. A difference between &#x02212;1.5 &#x0003c; HAL<sub>C</sub> &#x02212;HAL<sub>O</sub> &#x0003c; 1.5 was observed for 64% (N=269 cases), and between and &#x02212;2.0 &#x0003c; HAL<sub>C</sub> &#x02212; HAL<sub>O</sub> &#x0003c; 2.0 was observed for 77% (N=324 cases) of the data of the data, as shown in <xref rid="F2" ref-type="fig">Figure 2B</xref>. A difference between &#x02212;1.5 &#x0003c; HAL<sub>F</sub> &#x02212;HAL<sub>O</sub> &#x0003c; 1.5 was observed for 65% (N=271 cases), and between &#x02212;2.0 &#x0003c; HAL<sub>F</sub> &#x02212;HAL<sub>O</sub> &#x0003c; 2.0 was observed for 78% (327 cases) of the data, as shown in <xref rid="F2" ref-type="fig">Figure 2C</xref>.</p><p id="P29">Scatter plots for HAL<sub>C</sub> v. HAL<sub>F</sub>, HAL<sub>C</sub> v. HAL<sub>O</sub>, and HAL<sub>F</sub> v. HAL<sub>O</sub> are provided in <xref rid="F3" ref-type="fig">Figure 3</xref>. Linear regression between HAL<sub>C</sub> v. HAL<sub>F</sub> (<xref rid="F3" ref-type="fig">Figure 3A</xref>) had a coefficient of 1.03 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.89 when the intercept was set to zero, and a coefficient of 0.83 and an intercept of 0.91 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.57. Linear regression between HAL<sub>C</sub> v. HAL<sub>O</sub> (<xref rid="F3" ref-type="fig">Figure 3B</xref>) had a coefficient of 0.91 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.84 when the intercept was set to zero, and a coefficient of 0.73 and an intercept of 0.85 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.34. Linear regression between HAL<sub>F</sub> v. HAL<sub>O</sub> (<xref rid="F3" ref-type="fig">Figure 3C</xref>) had a coefficient of 0.84 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.86 when the intercept was set to zero, and a coefficient of 0.72 and an intercept of 0.57 for a coefficient of determination <italic toggle="yes">R</italic><sup><italic toggle="yes">2</italic></sup>=0.40.</p><p id="P30">Bland-Altman plots for HAL<sub>C</sub> &#x02212;HAL<sub>F</sub>, HAL<sub>C</sub>&#x02212;HAL<sub>O</sub>, and HAL<sub>F</sub> &#x02212;HAL<sub>O</sub> are provided in <xref rid="F4" ref-type="fig">Figure 4</xref>. The plot for the HAL<sub>C</sub> &#x02212;HAL<sub>F</sub> had 95% of the data between the upper limit of 3.13 and the lower limit of &#x02212;2.44, for a range of 5.57 (<xref rid="F4" ref-type="fig">Figure 4A</xref>). The plot for the HAL<sub>C</sub> &#x02212;HAL<sub>O</sub> had 95% of the data between the upper limit of 3.26 and the lower limit of &#x02212;3.72, for a range of 6.12 (<xref rid="F4" ref-type="fig">Figure 4B</xref>). The plot for the HAL<sub>F</sub> &#x02212;HAL<sub>O</sub> had 95% of the data between the upper limit of 2.49 and the lower limit of &#x02212;3.63, for a range of 6.98 (<xref rid="F4" ref-type="fig">Figure 4C</xref>).</p></sec><sec id="S11"><label>4.</label><title>Discussion</title><p id="P31">The objective of the current study was to compare the different methods for estimating HAL. Although the differences in HAL for the three methods were relatively small on average (&#x0003c; 1), the differences were statistically significant (<italic toggle="yes">p</italic>&#x0003c;.001). On average the ratings for HAL<sub>C</sub> and HAL<sub>F</sub> were the closest. A difference within &#x000b1;1 point on the HAL scale was considered equivalent. The HAL<sub>C</sub> and HAL<sub>F</sub> ratings were the most consistent; more than half (68%) of all the task ratings were within that range. Most of the data for HAL<sub>C</sub> and HAL<sub>F</sub> (89%) had differences less than &#x000b1;2 (<xref rid="F1" ref-type="fig">Figure 1A</xref>). The absolute difference between HAL<sub>C</sub> &#x02212;HAL<sub>F</sub> was smallest on average (mean=1.20, SD=0.83, 95% CI=0.11). The Bland-Altman analysis had similar findings, where a majority of the HAL values agreed within a similar margin. HAL<sub>C</sub> and HAL<sub>F</sub> had the greatest correlation (<italic toggle="yes">R</italic><sup>2</sup>=.89).</p><p id="P32">All three methods in the current study had better correlations among the three methods than those reported among individual analysts for observed HAL ratings by <xref rid="R32" ref-type="bibr">Spielholz et al. (2008)</xref>. They compared HAL<sub>O</sub> ratings among expert raters and had a Spearman <italic toggle="yes">r</italic> correlation of 0.67 while the correlation among experts and novice raters was 0.39. These results in the current study indicate that computed HAL values (HAL<sub>C</sub> and HAL<sub>F</sub>) were the most reliable and better correlated than when multiple observers rated the same videos.</p><p id="P33"><xref rid="R36" ref-type="bibr">Wurzelbacher et. al. (2010)</xref> compared observer rated HAL (HAL<sub>O</sub>) and calculated HAL based on single-frame video analysis and the ACGIH TLV integer HAL look-up table (HAL<sub>T</sub>). They reported that the Spearman correlation <italic toggle="yes">r</italic> correlation for HAL<sub>O</sub> and HAL<sub>T</sub> was 0.49. The percent of exact agreement was 22%, while agreement within &#x000b1;1 point on the HAL scale was 61%.</p><p id="P34">The consistency between definition of exertions for obtaining the frequency (F) was likely an important factor in gaining consistency between the calculated HAL measures (HAL<sub>C</sub> and HAL<sub>F</sub>). <xref rid="R5" ref-type="bibr">Bao et al. (2006b)</xref> found that different definitions of repetitive exertions produced different measures of repetitiveness and that under those circumstances their correlations were poor. Although on average the differences between the three methods for estimating HAL were small, the impact of averages on studies involving large cohorts may be less important than for HAL values used by practitioners where unreliable data for a single subject might be more consequential.</p><p id="P35">Values for HAL<sub>F</sub> and HAL<sub>C</sub> had good agreement despite that HAL<sub>F</sub> was calculated based on frequency (F) in <xref rid="FD3" ref-type="disp-formula">Equation 3</xref> while HAL<sub>C</sub> was calculated based on hand speed (S) in <xref rid="FD4" ref-type="disp-formula">Equation 4</xref>. The HAL scale is anchored by hand speed and proportion of exertions, which is better aligned with the speed/ duty cycle relationship described in <xref rid="FD4" ref-type="disp-formula">Equation 4</xref> for HAL<sub>C</sub>, rather than the frequency/ duty cycle relationship described in <xref rid="FD3" ref-type="disp-formula">Equation 3</xref> for HAL<sub>F</sub>. This might have occurred because the origin of <xref rid="FD3" ref-type="disp-formula">Equation 3</xref> (<xref rid="R30" ref-type="bibr">Radwin, et al., 2015</xref>) was developed by aligning its values with the TLV HAL table, which is based on F and D. This agreement provides further evidence that frequency measures used in <xref rid="FD3" ref-type="disp-formula">Equation 3</xref> for HAL<sub>F</sub>, and speed measures used for HAL<sub>O</sub> and HAL<sub>C</sub> in <xref rid="FD4" ref-type="disp-formula">Equation 4</xref> are consistent measures. The large variations in HAL<sub>O</sub> indicate that the observation method is less reliable than the single-frame or computer vision measures. Comparable agreement might be expected for HAL<sub>T</sub> and HAL<sub>C</sub> although lookup table values are discrete and lack the precision of an equation.</p><p id="P36">There are several qualifications that limit these findings. Since the video database was created for a different purpose, many of the videos were unsuitable for computer vision analysis. Although 419 videos out of 1,653 video clips (25%) were available for study, there is no indication that the excluded videos were systematically related to the HAL values. Exclusions were based on independent circumstances such as the videographer&#x02019;s location, camera movements such as panning or zooming, or extraneous objects interfering with a full video of the workers&#x02019; hands. All HAL<sub>O</sub> values were evaluated by a single observer, rather than multiple observers. Although the observer may have had a bias, it is assumed the bias was consistent among all HAL<sub>O</sub> estimates.</p><p id="P37">Considering the excluded videos, it is important that in practice, recordings be made appropriately for computer vision analysis. Videos should be focused on the hands from a vantage point perpendicular, or within &#x000b1;30&#x000b0; of perpendicular to the plane of greatest motion (<xref rid="R12" ref-type="bibr">Chen, et al., 2015</xref>) to minimize parallax error. Image motion should be kept at a minimum by fixating on the hands, avoiding panning or zooming, and using fixed focus lenses. The full video frame should be used for recording the hand motion, if possible. Obstructed views of the hands should also be avoided.</p><p id="P38">Since HAL is related to muscle exertions (muscle contractions), manual single-frame HAL<sub>F</sub> can sometimes be considered more accurate than computer vision HAL<sub>C</sub>. This is because HAL is related to muscle exertions (muscle contractions) that can occur with movement (dynamic muscle contractions) or without movement (isometric muscle contractions). In some cases, such as when operating a power hand tool, although there is no observable movement during the exertions, their occurrence may be associated with corresponding events such as squeezing a trigger, or the sound made by the tool. In these cases, a human analyst may be able to detect the exertions, where computer vision may not. HAL<sub>F</sub> was demonstrated reliable (<xref rid="R36" ref-type="bibr">Wurzelbacher, et al., 2010</xref>) and utilized in the ULMSDC prospective studies that demonstrated the predictivity of the TLV<sup>&#x000ae;</sup> for HAL (<xref rid="R17" ref-type="bibr">Garg, et al., 2012</xref>; <xref rid="R38" ref-type="bibr">Yung et al., 2019</xref>; <xref rid="R25" ref-type="bibr">Kapellusch et al., 2014a</xref>; <xref rid="R38" ref-type="bibr">Yung et al., 2019</xref>; <xref rid="R25" ref-type="bibr">Kapellusch et al., 2014a</xref>; <xref rid="R9" ref-type="bibr">Burt, et al., 2013</xref>; <xref rid="R26" ref-type="bibr">Kapellusch et al., 2014b</xref>), and thus is the most validated method. Since HAL<sub>C</sub> is based on a computer algorithm, its re-test reliability should not be an issue, although it should be formally tested in follow-on studies.</p><p id="P39">While computer vision was utilized in the current study, other researchers have incorporated continuous measurement methods such as inertial measurement unit sensors (<xref rid="R34" ref-type="bibr">Thamsuwan, et al., 2020</xref>) which may be an alternative method for making direct HAL measures. These types of measures should be compared with computer vision in future investigations.</p><p id="P40">Although manual single-frame MVTA analysis is considered more time consuming than automated computer vision analysis, we are not aware of any benchmarks for which to compare times and analysis time was not recorded for the current study. The time to do a single-frame analysis is related to the frequency of exertions and the cycle time. The more frequent exertions occur, or the longer the cycle time, the more time the analyst needs to take to code them. The analysis time also depends on the required accuracy where the video has to pause longer and more often when a more accurate measure is necessary.</p></sec><sec id="S12"><label>5.</label><title>Conclusions</title><p id="P41">The results of the current study suggest that the computer vision methodology mostly yielded comparable results as single-frame video analysis. The potential advantages of an automated method include objectivity and that computer vision analysis has the potential to require considerably less analyst time than single-frame video analysis.</p><p id="P42">Given that there is external validity for the ACGIH TLV<sup>&#x000ae;</sup> for HAL, having more objective and efficient methods of applying the TLV should be useful in practice. Since there is good epidemiologic evidence of an association between the TLV<sup>&#x000ae;</sup> for HAL and incident CTS, computer vision shows promise for increasing efficiency and objectivity for assigning HAL ratings, which could improve adoption of the method by practitioners.</p><p id="P43">This study concludes that computed methods for calculating HAL are more consistent and reliable than observation. Computer vision methods for estimating HAL had better agreement with single-frame methods than with observation.</p></sec></body><back><ack id="S13"><title>Acknowledgements</title><p id="P44">The authors wish to thank John Wallner and Callahan Manuel for their assistance with data analysis.</p><sec id="S14"><title>Funding</title><p id="P45">This work was supported, in part, by a grant from the National Institute for Occupational Safety and Health (NIOSH/CDC) grant number R01-OH-011024 (Radwin). 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