Intussusception Cases Among Children Admitted to Referral Hospitals in Kenya, 2002–2013: Implications for Monitoring Postlicensure Safety of Rotavirus Vaccines in Africa

Details

• Alternative Title:
  J Pediatric Infect Dis Soc
• Personal Author:
  Omore, Richard ; Osawa, Francis ; Musia, Janet ; Rha, Brian ; Ismail, Amina ; Kiulia, Nicholas Mukaria ; Moke, Fenny ; Vulule, John ; Wainaina, Anthony Mungai ; Tole, John ; Machoki, Stanley Mugambi ; Nuorti, J. Pekka ; Breiman, Robert F. ; Parashar, Umesh D. ; Montgomery, Joel M. ; Tate, Jacqueline E.
• Description:
  To describe the epidemiology of intussusception before introduction of the rotavirus vaccine, we reviewed the records of 280 patients younger than 5 years who were hospitalized in Kenya between 2002 and 2013. The patients who died (18 [6.4%]) had sought care later after symptom onset than the patients who survived (median, 5 vs 3 days, respectively; P = .04). Seeking prompt care may improve therapeutic outcomes.
• Subjects:
  Article Child, Preschool Childhood Mortality Female Humans Infant Infant, Newborn Intussusception Kenya Male Patient Safety Product Surveillance, Postmarketing Referral And Consultation Retrospective Studies Risk Factors Rotavirus Infections Rotavirus Vaccines

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• Source:
  J Pediatric Infect Dis Soc. 5(4):465-469
• Pubmed ID:
  26407281
• Pubmed Central ID:
  PMC8721673
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  Kenya
• Volume:
  5
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:646fe6d877f2846250cb161b5730eca3ab2add173126371f381f0579b597a269
• Download URL:
  https://stacks.cdc.gov/view/cdc/113052/cdc_113052_DS1.pdf
• File Type:
  [PDF - 62.95 KB ]