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  • Linkage Disequilibrium (20)
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Linkage Disequilibrium
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  • Linkage Disequi (20) Remove Filter
  • South American Plasmodium falciparum after the Malaria Eradication Era Clonal Population Expansion and Survival of the Fittest Hybrids
    South American Plasmodium falciparum after the Malaria Eradication Era: Clonal Population Expansion and Survival of the Fittest Hybrids
    :
    Griffing, Sean M. ;
    Mixson-Hayden, Tonya
    Sep 16 2011 | PLoS One. 2011; 6(9).
    :
    Malaria has reemerged in many regions where once it was nearly eliminated. Yet the source of these parasites, the process of repopulation, their popul...
  • Cryptosporidium parvum IId family clonal population and dispersal from Western Asia to other geographical regions
    Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
    :
    Wang, Rongjun ;
    Zhang, Longxian
    Feb 27 2014 | Sci Rep. 2014; 4.
    :
    In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequenc...
  • Genetic Recombination and Cryptosporidium hominis Virulent Subtype IbA10G2
    Genetic Recombination and Cryptosporidium hominis Virulent Subtype IbA10G2
    :
    Li, Na ;
    Xiao, Lihua
    Oct 2013 | Emerg Infect Dis. 19(10):1573-1582.
    :
    Little is known about the emergence and spread of virulent subtypes of Cryptosporidium hominis, the predominant species responsible for human cryptosp...
  • The power of genetic diversity in genomewide association studies of lipids
    The power of genetic diversity in genome-wide association studies of lipids
    :
    Graham, Sarah E ;
    Clarke, Shoa L
    12 2021 | Nature. 600(7890):675-679
    :
    Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns...
  • SNP ascertainment bias in population genetic analyses Why it is important and how to correct it
    SNP ascertainment bias in population genetic analyses: Why it is important, and how to correct it
    :
    Lachance, Joseph ;
    Tishkoff, Sarah A.
    Jul 09 2013 | Bioessays. 35(9):780-786.
    :
    Whole genome sequencing and SNP genotyping arrays can paint strikingly different pictures of demographic history and natural selection. This is becaus...
  • GENOME WIDE IDENTIFICATION OF NEW GENES AND PATHWAYS IN PATIENTS WITH BOTH AUTOIMMUNE THYROIDITIS AND TYPE 1 DIABETES
    GENOME WIDE IDENTIFICATION OF NEW GENES AND PATHWAYS IN PATIENTS WITH BOTH AUTOIMMUNE THYROIDITIS AND TYPE 1 DIABETES
    :
    Tomer, Yaron ;
    Dolan, Lawrence M.
    Apr 27 2015 | J Autoimmun. 2015; 60:32-39.
    :
    Autoimmune thyroid diseases (AITD) and Type 1 diabetes (T1D) frequently occur in the same individual pointing to a strong shared genetic susceptibilit...
  • A genomewide association study of venous thromboembolism identifies risk variants in chromosomes 1q242 and 9q
    A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q
    :
    Heit, John A. ;
    Armasu, Sebastian M.
    8 2012 | J Thromb Haemost. 2012; 10(8):1521-1531
    :
    ObjectivesTo identify venous thromboembolism (VTE) disease-susceptibility genes.Patients/MethodsWe performed in silico genome wide association (GWAS) ...
  • New gene variants associated with venous thrombosis a replication study in White and Black Americans
    New gene variants associated with venous thrombosis: a replication study in White and Black Americans
    :
    AUSTIN, H. ;
    DE STAERCKE, C.
    3 2011 | J Thromb Haemost. 9(3):489-495
    :
    BackgroundWe evaluated 10 single-nucleotide polymorphisms (SNPs) identified in three European case–control studies as risk factors for venous thromb...
  • Characterizing Genetic Risk at Known Prostate Cancer Susceptibility Loci in Black or African American
    Characterizing Genetic Risk at Known Prostate Cancer Susceptibility Loci in Black or African American
    :
    Haiman, Christopher A. ;
    Chen, Gary K.
    May 26 2011 | PLoS Genet. 2011; 7(5).
    :
    GWAS of prostate cancer have been remarkably successful in revealing common genetic variants and novel biological pathways that are linked with its et...
  • Genetic variants in microRNAs and breast cancer risk in African American and European American women
    Genetic variants in microRNAs and breast cancer risk in African American and European American women
    :
    Yao, Song ;
    Graham, Kelly
    Sep 24 2013 | Breast Cancer Res Treat. 141(3):447-459.
    :
    MicroRNAs (miRNAs) are an integral part of the post-transcriptional machinery of gene expression and have been implicated in the carcinogenic cascade....
  • The association of variants in the FTO gene with longitudinal body mass index profiles in nonHispanic white children and adolescents
    The association of variants in the FTO gene with longitudinal body mass index profiles in non-Hispanic white children and adolescents
    :
    Hallman, D. Michael ;
    Friedel, Victoria C.
    Oct 11 2011 | Int J Obes (Lond). 36(1):61-68.
    :
    ObjectiveTo investigate possible age-related changes in associations between polymorphisms in the fat mass and obesity-associated (FTO) gene and highe...
  • Positive Selection in the Chromosome 16 VKORC1 Genomic Region Has Contributed to the Variability of Anticoagulant Response in Humans
    Positive Selection in the Chromosome 16 VKORC1 Genomic Region Has Contributed to the Variability of Anticoagulant Response in Humans
    :
    Patillon, Blandine ;
    Luisi, Pierre
    Dec 28 2012 | PLoS One. 2012; 7(12).
    :
    VKORC1 (vitamin K epoxide reductase complex subunit 1, 16p11.2) is the main genetic determinant of human response to oral anticoagulants of antivitami...
  • Raceethnic differences in the association of genetic loci with HbA1c levels and mortality in US adults the third National Health and Nutrition Examination Survey NHANES III
    Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III)
    :
    Grimsby, Jonna L. ;
    Porneala, Bianca C.
    Apr 27 2012 | BMC Med Genet. 2012; 13:30.
    :
    BackgroundHemoglobin A1c (HbA1c) levels diagnose diabetes, predict mortality and are associated with ten single nucleotide polymorphisms (SNPs) in whi...
  • Vitamin D metabolic loci and vitamin D status in Black and White pregnant women
    Vitamin D metabolic loci and vitamin D status in Black and White pregnant women
    :
    Baca, Katharyn M. ;
    Govil, Manika
    November 16 2017 | Eur J Obstet Gynecol Reprod Biol. 220:61-68
    :
    BackgroundSeveral candidate genes and genome wide association studies have reported significant associations between vitamin D metabolism genes and 25...
  • Genetic Indicators of Drug Resistance in the Highly Repetitive Genome of Trichomonas vaginalis
    Genetic Indicators of Drug Resistance in the Highly Repetitive Genome of Trichomonas vaginalis
    :
    Bradic, Martina ;
    Warring, Sally D.
    Jun 19 2017 | Genome Biol Evol. 2017; 9(6):1658-1672.
    :
    Trichomonas vaginalis, the most common non-viral sexually transmitted parasite, causes ∼283 million trichomoniasis infections annually and is associ...
  • BMI1 enhancer polymorphism underlies chromosome 10p1231 association with childhood acute lymphoblastic leukemia
    BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia
    :
    de Smith, Adam J. ;
    Walsh, Kyle M.
    12 01 2018 | Int J Cancer. 143(11):2647-2658
    :
    Genome-wide association studies of childhood acute lymphoblastic leukemia (ALL) have identified regions of association at PIP4K2A and upstream of BMI1...
  • Association of MHC region SNPs with irritant susceptibility in healthcare workers
    Association of MHC region SNPs with irritant susceptibility in healthcare workers
    :
    Yucesoy, Berran ;
    Talzhanov, Yerkebulan
    9 2016 | J Immunotoxicol. 13(5):738-744
    :
    Irritant contact dermatitis is the most common work-related skin disease, especially affecting workers in "wet-work" occupations. This study was condu...
  • A genomewide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis
    A genome-wide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis
    :
    Justice, Cristina M ;
    Cuellar, Araceli
    8 2020 | Hum Genet. 139(8):1077-1090
    :
    Our previous genome-wide association study (GWAS) for sagittal nonsyndromic craniosynostosis (sNCS) provided important insights into the genetics of m...
  • Genetic modifiers of radon induced lung cancer risk A genomewide interaction study in former uranium miners
    Genetic modifiers of radon induced lung cancer risk - A genome-wide interaction study in former uranium miners
    :
    Rosenberger, Albert ;
    Hung, Rayjean J
    11 2018 | Int Arch Occup Environ Health. 91(8):937-950
    :
    PurposeRadon is a risk factor for lung cancer and uranium miners are more exposed than the general population. A genome-wide interaction analysis was ...
  • Opioid use disorder deaths and the effects of medication therapy
    Opioid use disorder deaths and the effects of medication therapy
    :
    Mannelli, Paolo ;
    Wu, Li-Tzy
    2019 | Am J Drug Alcohol Abuse. 45(3):227-229
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