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Genome engineering using the CRISPR-Cas9 system

CITE Title : Genome engineering using the CRISPR-Cas9 system Personal Author(s) : Ran, F. Ann;Hsu, Patrick D.;Wright, Jason;Agarwala, Vineeta;Scott, David A.;Zhang, Feng; Published Date : Oct 24 2013 Source : Nat Protoc. 2013; 8(11):2281-2308. URL : https://stacks.cdc.gov/view/cdc/29900 Ran, F. Ann et al. (2013). Genome engineering using the CRISPR-Cas9 system. 8(11). Ran, F. Ann et al. "Genome engineering using the CRISPR-Cas9 system" 8, no. 11 (2013) Ran, F. Ann et al. "Genome engineering using the CRISPR-Cas9 system" vol. 8, no. 11, 2013 Export RIS Citation Information.

:

Ran, F. Ann ;

Hsu, Patrick D.

Oct 24 2013 | Nat Protoc. 2013; 8(11):2281-2308.

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Targeted nucleases are powerful tools for mediating genome alteration with high precision. The RNA-guided Cas9 nuclease from the microbial clustered r...
Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association

CITE Title : Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association Personal Author(s) : Sarangi, Prabha;Bartosova, Zdenka;Altmannova, Veronika;Holland, Cory;Chavdarova, Melita;Lee, Sang Eun;Krejci, Lumir;Zhao, Xiaolan; Published Date : Apr 20 2014 Source : Nucleic Acids Res. 2014; 42(10):6393-6404. URL : https://stacks.cdc.gov/view/cdc/32202 Sarangi, Prabha et al. (2014). Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association. 42(10). Sarangi, Prabha et al. "Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association" 42, no. 10 (2014) Sarangi, Prabha et al. "Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association" vol. 42, no. 10, 2014 Export RIS Citation Information.

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Sarangi, Prabha ;

Bartosova, Zdenka

Apr 20 2014 | Nucleic Acids Res. 2014; 42(10):6393-6404.

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The Saccharomyces cerevisiae Rad1-Rad10 complex is a conserved, structure-specific endonuclease important for repairing multiple types of DNA lesions....
Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis

CITE Title : Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis Personal Author(s) : Farhat, Maha R.;Shapiro, B. Jesse;Kieser, Karen J.;Sultana, Razvan;Jacobson, Karen R.;Victor, Thomas C.;Warren, Robin M.;Streicher, Elizabeth M;Calver, Alistair;Sloutsky, Alex;Kaur, Devinder;Posey, Jamie E.;Plikaytis, Bonnie;Oggioni, Marco R.;Gardy, Jennifer L.;Johnston, James C.;Rodrigues, Mabel;Tang, Patrick K. C.;Kato-Maeda, Midori;Borowsky, Mark L.;Muddukrishna, Bhavana;Kreiswirth, Barry N.;Kurepina, Natalia;Galagan, James;Gagneux, Sebastien;Birren, Bruce;Rubin, Eric J.;Lander, Eric S.;Sabeti, Pardis C.;Murray, Megan; Published Date : Sep 01 2013 Source : Nat Genet. 45(10). URL : https://stacks.cdc.gov/view/cdc/28569 Farhat, Maha R. et al. (2013). Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis. 45(10). Farhat, Maha R. et al. "Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis" 45, no. 10 (2013) Farhat, Maha R. et al. "Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis" vol. 45, no. 10, 2013 Export RIS Citation Information.

:

Farhat, Maha R. ;

Shapiro, B. Jesse

Sep 01 2013 | Nat Genet. 45(10).

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M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis epidemic control. Mechanisms of resistance, including genetic ...
Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida

CITE Title : Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida Personal Author(s) : Cao, Xuanye;Tian, Tian;Steele, John W.;Cabrera, Robert M.;Aguiar-Pulido, Vanessa;Wadhwa, Shruti;Bhavani, Nikitha;Bi, Patrick;Gargurevich, Nick H.;Hoffman, Ethan N.;Cai, Chun-Quan;Marini, Nicholas J.;Yang, Wei;Shaw, Gary M.;Ross, Margaret E.;Finnell, Richard H.;Lei, Yunping; Published Date : 4 2020;4-2020; Source : Hum Mutat. 41(4):786-799 URL : https://stacks.cdc.gov/view/cdc/87325 Cao, Xuanye et al. (2020). Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida. 41(4). Cao, Xuanye et al. "Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida" 41, no. 4 (2020) Cao, Xuanye et al. "Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida" vol. 41, no. 4, 2020 Export RIS Citation Information.

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Cao, Xuanye ;

Tian, Tian

4 2020 | Hum Mutat. 41(4):786-799

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DNA damage response (DDR) genes orchestrating the network of DNA repair, cell cycle control, are essential for the rapid proliferation of neural proge...
Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders

CITE Title : Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders Personal Author(s) : Buchbinder, David;Hauck, Fabian;Albert, Michael H.;Rack, Anita;Bakhtiar, Shahrzad;Shcherbina, Anna;Deripapa, Elena;Sullivan, Kathleen E.;Perelygina, Ludmila;Eloit, Marc;Neven, Bénédicte;Pérot, Philippe;Moshous, Despina;Suarez, Félipe;Bodemer, Christine;Bonilla, Francisco A.;Vaz, Louise E.;Krol, Alfons L.;Klein, Christoph;Seppanen, Mikko;Nugent, Diane J.;Singh, Jasjit;Ochs, Hans D.; Published Date : January 03 2019 Source : J Clin Immunol. 39(1):81-89 URL : https://stacks.cdc.gov/view/cdc/99036 Buchbinder, David et al. (2019). Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders. 39(1). Buchbinder, David et al. "Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders" 39, no. 1 (2019) Buchbinder, David et al. "Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders" vol. 39, no. 1, 2019 Export RIS Citation Information.

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Buchbinder, David ;

Hauck, Fabian

January 03 2019 | J Clin Immunol. 39(1):81-89

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The association of immunodeficiency-related vaccine-derived rubella virus (iVDRV) with cutaneous and visceral granulomatous disease has been reported ...
Genetic polymorphisms modify bladder cancer recurrence and survival in a U.S. population-based prognostic study

CITE Title : Genetic polymorphisms modify bladder cancer recurrence and survival in a U.S. population-based prognostic study Personal Author(s) : Andrew, Angeline S.;Gui, Jiang;Hu, Ting;Wyszynski, Asaf;Marsit, Carmen J.;Kelsey, Karl T.;Schned, Alan R.;Tanyos, Sam A.;Pendleton, Eben M.;Ekstrom, Rebecca M.;Li, Zhongze;Zens, Michael S.;Borsuk, Mark;Moore, Jason H.;Karagas, Margaret R.; Published Date : 2 2015;2-2015; Source : BJU Int. 115(2):238-247 URL : https://stacks.cdc.gov/view/cdc/32852 Andrew, Angeline S. et al. (2015). Genetic polymorphisms modify bladder cancer recurrence and survival in a U.S. population-based prognostic study. 115(2). Andrew, Angeline S. et al. "Genetic polymorphisms modify bladder cancer recurrence and survival in a U.S. population-based prognostic study" 115, no. 2 (2015) Andrew, Angeline S. et al. "Genetic polymorphisms modify bladder cancer recurrence and survival in a U.S. population-based prognostic study" vol. 115, no. 2, 2015 Export RIS Citation Information.

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Andrew, Angeline S. ;

Gui, Jiang

2 2015 | BJU Int. 115(2):238-247

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ObjectiveTo identify genetic variants that modify bladder cancer prognosis focusing on genes involved in major biological carcinogenesis processes (ap...
Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.

CITE Title : Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents. Personal Author(s) : Byfield, J. E.;Murnane, J.;Ward, J. F.;Calabro-Jones, P.;Lynch, M.;Kulhanian, F.; Published Date : May 1981 Source : Br J Cancer. 43(5):669-683. URL : https://stacks.cdc.gov/view/cdc/22954 Byfield, J. E. et al. (1981). Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.. 43(5). Byfield, J. E. et al. "Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents." 43, no. 5 (1981) Byfield, J. E. et al. "Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents." vol. 43, no. 5, 1981 Export RIS Citation Information.

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Byfield, J. E. ;

Murnane, J.

May 1981 | Br J Cancer. 43(5):669-683.

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The relationships between DNA damage from UV radiation, alkylating drugs and the methylated xanthines (MX) have been studied in normal and malignant r...
Multiple rpoB Mutants of Mycobacterium tuberculosis and Second-order Selection

CITE Title : Multiple rpoB Mutants of Mycobacterium tuberculosis and Second-order Selection Personal Author(s) : Mokrousov, Igor Published Date : Jul 2004 Source : Emerg Infect Dis. 10(7):1337-1338. URL : https://stacks.cdc.gov/view/cdc/14449 Mokrousov, Igor (2004). Multiple rpoB Mutants of Mycobacterium tuberculosis and Second-order Selection. 10(7). Mokrousov, Igor "Multiple rpoB Mutants of Mycobacterium tuberculosis and Second-order Selection" 10, no. 7 (2004) Mokrousov, Igor "Multiple rpoB Mutants of Mycobacterium tuberculosis and Second-order Selection" vol. 10, no. 7, 2004 Export RIS Citation Information.

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Mokrousov, Igor

Jul 2004 | Emerg Infect Dis. 10(7):1337-1338.

No Description
Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

CITE Title : Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic Personal Author(s) : Nouvel, Laurent X.;Kassa-Kelembho, Eric;Dos Vultos, Tiago;Zandanga, Germain;Rauzier, Jean;Lafoz, Carmen;Martin, Carlos;Blazquez, Jesus;Talarmin, Antoine;Gicquel, Brigitte; Published Date : Sep 2006 Source : Emerg Infect Dis. 12(9):1454-1456. URL : https://stacks.cdc.gov/view/cdc/16291 Nouvel, Laurent X. et al. (2006). Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic. 12(9). Nouvel, Laurent X. et al. "Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic" 12, no. 9 (2006) Nouvel, Laurent X. et al. "Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic" vol. 12, no. 9, 2006 Export RIS Citation Information.

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Nouvel, Laurent X. ;

Kassa-Kelembho, Eric

Sep 2006 | Emerg Infect Dis. 12(9):1454-1456.

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We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligo...
Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family

CITE Title : Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family Personal Author(s) : Rad, Mina Ebrahimi;Bifani, Pablo;Martin, Carlos;Kremer, Kristin;Samper, Sofia;Rauzier, Jean;Kreiswirth, Barry;Blazquez, Jesus;Jouan, Marc;van Soolingen, Dick;Gicquel, Brigitte; Published Date : Jul 2003 Source : Emerg Infect Dis. 9(7):838-845. URL : https://stacks.cdc.gov/view/cdc/14198 Rad, Mina Ebrahimi et al. (2003). Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family. 9(7). Rad, Mina Ebrahimi et al. "Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family" 9, no. 7 (2003) Rad, Mina Ebrahimi et al. "Mutations in Putative Mutator Genes of Mycobacterium tuberculosis Strains of the W-Beijing Family" vol. 9, no. 7, 2003 Export RIS Citation Information.

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Rad, Mina Ebrahimi ;

Bifani, Pablo

Jul 2003 | Emerg Infect Dis. 9(7):838-845.

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Alterations in genes involved in the repair of DNA mutations (mut genes) result in an increased mutation frequency and better adaptability of the bact...
Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae

CITE Title : Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae Personal Author(s) : Stephenson, Adrienne P.;Mazu, Tryphon K.;Miles, Jana S.;Freeman, Miles D.;Reams, R. Renee;Flores-Rozas, Hernan; Published Date : Oct 27 2013 Source : Biomed Res Int. 2013; 2013. URL : https://stacks.cdc.gov/view/cdc/22548 Stephenson, Adrienne P. et al. (2013). Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae. 2013 Stephenson, Adrienne P. et al. "Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae" 2013 (2013) Stephenson, Adrienne P. et al. "Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae" vol. 2013, 2013 Export RIS Citation Information.

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Stephenson, Adrienne P. ;

Mazu, Tryphon K.

Oct 27 2013 | Biomed Res Int. 2013; 2013.

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Manganese (Mn) is essential for normal physiologic functioning; therefore, deficiencies and excess intake of manganese can result in disease. In human...
Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses

CITE Title : Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses Personal Author(s) : Wilson, David L.;Beharry, Andrew A.;Srivastava, Avinash;O’Connor, Timothy R.;Kool, Eric T.; Published Date : 9 24 2018;9-24-; Source : Angew Chem Int Ed Engl. 57(39):12896-12900 URL : https://stacks.cdc.gov/view/cdc/77841 Wilson, David L. et al. (2018). Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses. 57(39). Wilson, David L. et al. "Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses" 57, no. 39 (2018) Wilson, David L. et al. "Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses" vol. 57, no. 39, 2018 Export RIS Citation Information.

:

Wilson, David L.

;

Beharry, Andrew A.

9 24 2018 | Angew Chem Int Ed Engl. 57(39):12896-12900

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The DNA repair enzyme ALKBH2 is implicated in both tumorigenesis as well as resistance to chemotherapy in certain cancers. It is currently under study...
R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts

CITE Title : R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts Personal Author(s) : Liu, Zhiyan Silvia;Sinha, Sayantani;Bannister, Maxwell;Song, Axia;Arriaga-Gomez, Erica;McKeeken, Alexander J.;Bonner, Elizabeth A.;Hanson, Benjamin K.;Sarchi, Martina;Takashima, Kouhei;Zong, Dawei;Corral, Victor M.;Nguyen, Evan;Yoo, Jennifer;Chiraphapphaiboon, Wannasiri;Leibson, Cassandra;McMahon, Matthew C.;Rai, Sumit;Swisher, Elizabeth M.;Sachs, Zohar;Chatla, Srinivas;Stirewalt, Derek L.;Deeg, H. Joachim;Skorski, Tomasz;Papapetrou, Eirini P.;Walter, Matthew J.;Graubert, Timothy A.;Doulatov, Sergei;Lee, Stanley C.;Nguyen, Hai Dang; Published Date : 2 15 2024;2-15-; Source : Cancer Res. 84(4):577-597 URL : https://stacks.cdc.gov/view/cdc/151645 Liu, Zhiyan Silvia et al. (2024). R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts. 84(4). Liu, Zhiyan Silvia et al. "R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts" 84, no. 4 (2024) Liu, Zhiyan Silvia et al. "R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts" vol. 84, no. 4, 2024 Export RIS Citation Information.

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Liu, Zhiyan Silvia ;

Sinha, Sayantani

2 15 2024 | Cancer Res. 84(4):577-597

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RNA splicing factor (SF) gene mutations are commonly observed in patients with myeloid malignancies. Here we showed that SRSF2- and U2AF1-mutant leuke...
An integer optimization algorithm for robust identification of non-linear gene regulatory networks

CITE Title : An integer optimization algorithm for robust identification of non-linear gene regulatory networks Personal Author(s) : Chemmangattuvalappil, Nishanth;Task, Keith;Banerjee, Ipsita; Published Date : Sep 02 2012 Source : BMC Syst Biol. 2012; 6:119. URL : https://stacks.cdc.gov/view/cdc/22707 Chemmangattuvalappil, Nishanth et al. (2012). An integer optimization algorithm for robust identification of non-linear gene regulatory networks. 6 Chemmangattuvalappil, Nishanth and Task, Keith and Banerjee, Ipsita "An integer optimization algorithm for robust identification of non-linear gene regulatory networks" 6 (2012) Chemmangattuvalappil, Nishanth et al. "An integer optimization algorithm for robust identification of non-linear gene regulatory networks" vol. 6, 2012 Export RIS Citation Information.

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Chemmangattuvalappil, Nishanth ;

Task, Keith

Sep 02 2012 | BMC Syst Biol. 2012; 6:119.

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BackgroundReverse engineering gene networks and identifying regulatory interactions are integral to understanding cellular decision making processes. ...