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Impaired Mucus Detachment Disrupts Mucociliary Transport in a Piglet Model of Cystic Fibrosis

CITE Title : Impaired Mucus Detachment Disrupts Mucociliary Transport in a Piglet Model of Cystic Fibrosis Personal Author(s) : Hoegger, Mark J.;Fischer, Anthony J.;McMenimen, James D.;Ostedgaard, Lynda S.;Tucker, Alex J.;Awadalla, Maged A.;Moninger, Thomas O.;Michalski, Andrew S.;Hoffman, Eric A.;Zabner, Joseph;Stoltz, David A.;Welsh, Michael J.; Published Date : Aug 15 2014 Source : Science. 345(6198):818-822. URL : https://stacks.cdc.gov/view/cdc/30313 Hoegger, Mark J. et al. (2014). Impaired Mucus Detachment Disrupts Mucociliary Transport in a Piglet Model of Cystic Fibrosis. 345(6198). Hoegger, Mark J. et al. "Impaired Mucus Detachment Disrupts Mucociliary Transport in a Piglet Model of Cystic Fibrosis" 345, no. 6198 (2014) Hoegger, Mark J. et al. "Impaired Mucus Detachment Disrupts Mucociliary Transport in a Piglet Model of Cystic Fibrosis" vol. 345, no. 6198, 2014 Export RIS Citation Information.

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Hoegger, Mark J. ;

Fischer, Anthony J.

Aug 15 2014 | Science. 345(6198):818-822.

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Lung disease in people with cystic fibrosis (CF) is initiated by defective host defense that predisposes airways to bacterial infection. Advanced CF i...
Cell type-specific structural plasticity of the ciliary transition zone in C. elegans

CITE Title : Cell type-specific structural plasticity of the ciliary transition zone in C. elegans Personal Author(s) : Akella, Jyothi S.;Silva, Malan;Morsci, Natalia S.;Nguyen, Ken C.;Rice, William J.;Hall, David H.;Barr, Maureen M.; Published Date : February 14 2019 Source : Biol Cell. 111(4):95-107 URL : https://stacks.cdc.gov/view/cdc/83676 Akella, Jyothi S. et al. (2019). Cell type-specific structural plasticity of the ciliary transition zone in C. elegans. 111(4). Akella, Jyothi S. et al. "Cell type-specific structural plasticity of the ciliary transition zone in C. elegans" 111, no. 4 (2019) Akella, Jyothi S. et al. "Cell type-specific structural plasticity of the ciliary transition zone in C. elegans" vol. 111, no. 4, 2019 Export RIS Citation Information.

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Akella, Jyothi S. ;

Silva, Malan

February 14 2019 | Biol Cell. 111(4):95-107

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Background informationThe current consensus on cilia development posits that the ciliary transition zone (TZ) is formed via extension of nine centroso...
EFCAB7 and IQCE regulate Hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia

CITE Title : EFCAB7 and IQCE regulate Hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia Personal Author(s) : Pusapati, Ganesh V.;Hughes, Casey E;Dorn, Karolin V.;Zhang, Dapeng;Sugianto, Priscilla;Aravind, L.;Rohatgi, Rajat; Published Date : Feb 27 2014 Source : Dev Cell. 2014; 28(5):483-496. URL : https://stacks.cdc.gov/view/cdc/29962 Pusapati, Ganesh V. et al. (2014). EFCAB7 and IQCE regulate Hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia. 28(5). Pusapati, Ganesh V. et al. "EFCAB7 and IQCE regulate Hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia" 28, no. 5 (2014) Pusapati, Ganesh V. et al. "EFCAB7 and IQCE regulate Hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia" vol. 28, no. 5, 2014 Export RIS Citation Information.

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Pusapati, Ganesh V. ;

Hughes, Casey E

Feb 27 2014 | Dev Cell. 2014; 28(5):483-496.

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The Hedgehog (Hh) pathway depends on primary cilia in vertebrates, but the signaling machinery within cilia remains incompletely defined. We report ...
Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation

CITE Title : Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation Personal Author(s) : Wang, Yu;Arvanites, Anthony C.;Davidow, Lance;Blanchard, Joel;Lam, Kelvin;Yoo, Jin Woo;Coy, Shannon;Rubin, Lee L.;McMahon, Andrew P.; Published Date : 6 15 2012;6-15-; Source : ACS Chem Biol. 7(6):1040-1048 URL : https://stacks.cdc.gov/view/cdc/41941 Wang, Yu et al. (2012). Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation. 7(6). Wang, Yu et al. "Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation" 7, no. 6 (2012) Wang, Yu et al. "Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation" vol. 7, no. 6, 2012 Export RIS Citation Information.

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Wang, Yu ;

Arvanites, Anthony C.

6 15 2012 | ACS Chem Biol. 7(6):1040-1048

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Hedgehog (Hh) signaling promotes tumorigenesis. The accumulation of the membrane protein Smoothened (Smo) within the primary cilium (PC) is a key even...
Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating

CITE Title : Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating Personal Author(s) : Wyatt, T. A.;Wells, S. M.;Alsaidi, Z. A.;DeVasure, J. M.;Klein, E. B.;Bailey, K. L.;Sisson, J. H.; Published Date : Nov 06 2013 Source : Mediators Inflamm. 2013; 2013. URL : https://stacks.cdc.gov/view/cdc/22542 Wyatt, T. A. et al. (2013). Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating. 2013 Wyatt, T. A. et al. "Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating" 2013 (2013) Wyatt, T. A. et al. "Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating" vol. 2013, 2013 Export RIS Citation Information.

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Wyatt, T. A. ;

Wells, S. M.

Nov 06 2013 | Mediators Inflamm. 2013; 2013.

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The airway epithelium is exposed to alcohol during drinking through direct exhalation of volatized ethanol from the bronchial circulation. Alcohol exp...
Proteomic analysis of primary human airway epithelial cells exposed to the respiratory toxicant diacetyl

CITE Title : Proteomic analysis of primary human airway epithelial cells exposed to the respiratory toxicant diacetyl Personal Author(s) : Foster, Matthew W.;Gwinn, William M.;Kelly, Francine L.;Brass, David M.;Valente, Ashlee M.;Moseley, M. Arthur;Thompson, J. Will;Morgan, Daniel L.;Palmer, Scott M.; Published Date : 2 03 2017 Source : J Proteome Res. 16(2):538-549 URL : https://stacks.cdc.gov/view/cdc/112147 Foster, Matthew W. et al. (2017). Proteomic analysis of primary human airway epithelial cells exposed to the respiratory toxicant diacetyl. 16(2). Foster, Matthew W. et al. "Proteomic analysis of primary human airway epithelial cells exposed to the respiratory toxicant diacetyl" 16, no. 2 (2017) Foster, Matthew W. et al. "Proteomic analysis of primary human airway epithelial cells exposed to the respiratory toxicant diacetyl" vol. 16, no. 2, 2017 Export RIS Citation Information.

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Foster, Matthew W. ;

Gwinn, William M.

2 03 2017 | J Proteome Res. 16(2):538-549

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Occupational exposures to the diketone flavoring agent, diacetyl, have been associated with bronchiolitis obliterans, a rare condition of airway fibro...
Transcriptional analysis of Cystic Fibrosis airways at single cell resolution reveals altered epithelial cell states and composition

CITE Title : Transcriptional analysis of Cystic Fibrosis airways at single cell resolution reveals altered epithelial cell states and composition Personal Author(s) : Carraro, Gianni;Langerman, Justin;Sabri, Shan;Lorenzana, Zareeb;Purkayastha, Arunima;Zhang, Guangzhu;Konda, Bindu;Aros, Cody J.;Calvert, Ben A.;Szymaniak, Aleks;Wilson, Emily;Mulligan, Michael;Bhatt, Priyanka;Lu, Junjie;Vijayaraj, Preethi;Yao, Changfu;Shia, David W.;Lund, Andrew J.;Israely, Edo;Rickabaugh, Tammy M.;Ernst, Jason;Mense, Martin;Randell, Scott H.;Vladar, Eszter K.;Ryan, Amy L.;Plath, Kathrin;Mahoney, John E.;Stripp, Barry R.;Gomperts, Brigitte N.; Published Date : 5 2021;5-2021; Source : Nat Med. 27(5):806-814 URL : https://stacks.cdc.gov/view/cdc/116473 Carraro, Gianni et al. (2021). Transcriptional analysis of Cystic Fibrosis airways at single cell resolution reveals altered epithelial cell states and composition. 27(5). Carraro, Gianni et al. "Transcriptional analysis of Cystic Fibrosis airways at single cell resolution reveals altered epithelial cell states and composition" 27, no. 5 (2021) Carraro, Gianni et al. "Transcriptional analysis of Cystic Fibrosis airways at single cell resolution reveals altered epithelial cell states and composition" vol. 27, no. 5, 2021 Export RIS Citation Information.

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Carraro, Gianni ;

Langerman, Justin

5 2021 | Nat Med. 27(5):806-814

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Cystic fibrosis (CF) is a lethal autosomal recessive disorder that afflicts more than 70,000 people. People with CF experience multi-organ dysfunction...