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- :Kagan, Valerian E. ;Chu, Charleen T.Dec 01 2013 | Chem Phys Lipids. 2013; 179:64-69.:Cardiolipins (CLs) are ancient and unusual dimeric phospholipids localized in the plasma membrane of bacteria and in the inner mitochondrial membrane ...
- :Tyurina, Yulia Y. ;Domingues, Rosario M.Dec 12 2013 | Chem Phys Lipids. 2013; 179:3-10.:Cardiolipins, a class of mitochondria-specific lipid molecules, is one of the most unusual and ancient phospholipids found in essentially all living s...
- :Belikova, Natalia A. ;Glumac, Ashley L.August 09 2011 | J Neurosci Methods. 2011; 201(1):185-190:Ascorbate is a vital reductant/free radical scavenger in the CNS, whose content defines - to a large extent - the redox status and the antioxidant res...
- :Chu, Charleen T. ;Ji, JingSep 15 2013 | Nat Cell Biol. 15(10):1197-1205.:Recognition of injured mitochondria for degradation by macroautophagy is essential for cellular health, but the mechanisms remain poorly understood. C...
- :Ray, Nancy B. ;Durairaj, LakshmiSep 19 2010 | Nat Med. 16(10):1120-1127.:Pneumonia remains the leading cause of death from infection in the US, yet fundamentally new conceptual models underlying its pathogenesis have not em...
- :Tyurina, Yulia Y. ;Polimova, Anastasia M.Mar 05 2015 | Free Radic Res. 49(5):681-691.:Exposure to rotenone in vivo results in selective degeneration of dopaminergic neurons and development of neuropathologic features of Parkinson's...
- :Kagan, Valerian E. ;Tyurina, Yulia Y.February 19 2021 | Front Endocrinol (Lausanne). 2021; 11:A huge diversification of phospholipids, forming the aqueous interfaces of all biomembranes, cannot be accommodated within a simple concept of their r...
- :Kagan, Valerian E. ;Bayir, Hülya1-15- | Biochem Biophys Res Commun. 482(3):482-490:High fidelity of biological systems is frequently achieved by duplication of the essential intracellular machineries or, removal of the entire cell, w...
- :Tyurina, Yulia Y. ;Poloyac, Samuel M.6 2014 | Nat Chem. 6(6):542-552:The central role of mitochondria in metabolic pathways and in cell-death mechanisms requires sophisticated signalling systems. Essential in this signa...
- :Balasubramanian, Krishnakumar ;Maeda, AkihiroSep 22 2015 | Sci Signal. 8(395):ra95.:Among the distinct molecular signatures present in the mitochondrion is the tetra-acylated anionic phospholipid cardiolipin, a lipid also present in p...
- :Tyurina, Yulia Y. ;Winnica, Daniel E.8 2013 | Mol Nutr Food Res. 57(8):1410-1422:ScopeRotenone is a toxicant believed to contribute to the development of Parkinson's disease.Methods and resultsUsing human peripheral blood lymphocyt...
- :Tyurina, Yulia Y. ;St. Croix, Claudette M.7 2019 | J Leukoc Biol. 106(1):57-81:In addition to the known prominent role of polyunsaturated (phospho)lipids as structural blocks of biomembranes, there is an emerging understanding of...
- :Tyurina, Yulia Y. ;Kisin, Elena R.9 27 2011 | ACS Nano. 5(9):7342-7353:It is commonly believed that nanomaterials cause nonspecific oxidative damage. Our mass spectrometry-based oxidative lipidomics analysis of all major ...
- :Konduru, Nagarjun V. ;Tyurina, Yulia Y.Feb 09 2009 | PLoS ONE. 2009; 4(2).:Broad applications of single-walled carbon nanotubes (SWCNT) dictate the necessity to better understand their health effects. Poor recognition of non-...
- :Tyurina, Yulia Y. ;Tungekar, Muhammad A.Dec 28 2011 | FEBS Lett. 2011; 586(3):235-241.:Peroxidation of cardiolipin in mitochondria is essential for the execution of apoptosis. We suggested that integration of oleic acid into cardiolipin ...
- :Mao, Gaowei ;Qu, FengJan 05 2016 | ACS Chem Biol. 11(2):530-540.:While opto-genetics has proven to have tremendous value in revealing the functions of the macromolecular machinery in cells, it is not amenable to exp...
- :Maguire, John J. ;Tyurina, Yulia Y.1 2017 | Biochim Biophys Acta. 1862(1):8-24:Since its discovery 75years ago, a wealth of knowledge has accumulated on the role of cardiolipin, the hallmark phospholipid of mitochondria, in bioen...
- :Samhan-Arias, Alejandro K. ;Ji, JingMar 23 2012 | Biochim Biophys Acta. 2012; 1818(10):2413-2423.:Oxidized phospholipid species are important, biologically relevant, lipid signaling molecules that usually exist in low abundance in biological tissue...
- :Tyurin, Vladimir A. ;Yanamala, NaveenaNov 19 2012 | Biochemistry. 51(48):9736-9750.:Ca(2+)-independent lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a member of the phospholipase A(2) superfamily with a distinguishing chara...
- :Atkinson, Jeffrey ;Kapralov, Alexandr A.10 11 2011 | Nat Commun. 2:497:The risk of radionuclide release in terrorist acts or exposure of healthy tissue during radiotherapy demand potent radioprotectants/radiomitigators. I...
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