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Rationally engineered Cas9 nucleases with improved specificity

CITE Title : Rationally engineered Cas9 nucleases with improved specificity Personal Author(s) : Slaymaker, Ian M.;Gao, Linyi;Zetsche, Bernd;Scott, David A.;Yan, Winston X.;Zhang, Feng; Published Date : Dec 01 2015 Source : Science. 351(6268):84-88. URL : https://stacks.cdc.gov/view/cdc/37554 Slaymaker, Ian M. et al. (2015). Rationally engineered Cas9 nucleases with improved specificity. 351(6268). Slaymaker, Ian M. et al. "Rationally engineered Cas9 nucleases with improved specificity" 351, no. 6268 (2015) Slaymaker, Ian M. et al. "Rationally engineered Cas9 nucleases with improved specificity" vol. 351, no. 6268, 2015 Export RIS Citation Information.

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Slaymaker, Ian M. ;

Gao, Linyi

Dec 01 2015 | Science. 351(6268):84-88.

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The RNA-guided endonuclease Cas9 is a versatile genome-editing tool with a broad range of applications from therapeutics to functional annotation of g...
Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system

CITE Title : Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system Personal Author(s) : Zetsche, Bernd;Gootenberg, Jonathan S.;Abudayyeh, Omar O.;Slaymaker, Ian M.;Makarova, Kira S.;Essletzbichler, Patrick;Volz, Sara;Joung, Julia;van der Oost, John;Regev, Aviv;Koonin, Eugene V.;Zhang, Feng; Published Date : 10 22 2015;10-22-; Source : Cell. 163(3):759-771 URL : https://stacks.cdc.gov/view/cdc/37605 Zetsche, Bernd et al. (2015). Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system. 163(3). Zetsche, Bernd et al. "Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system" 163, no. 3 (2015) Zetsche, Bernd et al. "Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system" vol. 163, no. 3, 2015 Export RIS Citation Information.

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Zetsche, Bernd ;

Gootenberg, Jonathan S.

10 22 2015 | Cell. 163(3):759-771

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The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Cl...
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

CITE Title : C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector Personal Author(s) : Abudayyeh, Omar O.;Gootenberg, Jonathan S.;Konermann, Silvana;Joung, Julia;Slaymaker, Ian M.;Cox, David B.T.;Shmakov, Sergey;Makarova, Kira S.;Semenova, Ekaterina;Minakhin, Leonid;Severinov, Konstantin;Regev, Aviv;Lander, Eric S.;Koonin, Eugene V.;Zhang, Feng; Published Date : Jun 02 2016 Source : Science. 353(6299):aaf5573. URL : https://stacks.cdc.gov/view/cdc/42943 Abudayyeh, Omar O. et al. (2016). C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector. 353(6299). Abudayyeh, Omar O. et al. "C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector" 353, no. 6299 (2016) Abudayyeh, Omar O. et al. "C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector" vol. 353, no. 6299, 2016 Export RIS Citation Information.

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Abudayyeh, Omar O. ;

Gootenberg, Jonathan S.

Jun 02 2016 | Science. 353(6299):aaf5573.

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The clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated genes (Cas) adaptive immune system defends microbes against fo...