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A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus

CITE Title : A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus Personal Author(s) : Flint, Mike;Chatterjee, Payel;Lin, David L.;McMullan, Laura K.;Shrivastava-Ranjan, Punya;Bergeron, Éric;Lo, Michael K.;Welch, Stephen R.;Nichol, Stuart T.;Tai, Andrew W.;Spiropoulou, Christina F.; Published Date : January 17 2019 Source : Nat Commun. 10 URL : https://stacks.cdc.gov/view/cdc/75846 Flint, Mike et al. (2019). A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus. 10 Flint, Mike et al. "A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus" 10 (2019) Flint, Mike et al. "A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus" vol. 10, 2019 Export RIS Citation Information.

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Flint, Mike ;

Chatterjee, Payel

January 17 2019 | Nat Commun. 10

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There are no approved therapies for Ebola virus infection. Here, to find potential therapeutic targets, we perform a screen for genes essential for Eb...
Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

CITE Title : Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture Personal Author(s) : Shrivastava-Ranjan, Punya;Lo, Michael K.;Chatterjee, Payel;Flint, Mike;Nichol, Stuart T.;Montgomery, Joel M.;O'Keefe, Barry R.;Spiropoulou, Christina F.; Published Date : November 04 2020 Source : Front Cell Infect Microbiol. 2020; 10 URL : https://stacks.cdc.gov/view/cdc/100845 Shrivastava-Ranjan, Punya et al. (2020). Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture. 10 Shrivastava-Ranjan, Punya et al. "Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture" 10 (2020) Shrivastava-Ranjan, Punya et al. "Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture" vol. 10, 2020 Export RIS Citation Information.

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Shrivastava-Ranjan, Punya ;

Lo, Michael K.

November 04 2020 | Front Cell Infect Microbiol. 2020; 10

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Andes virus (ANDV) and Sin Nombre virus (SNV), highly pathogenic hantaviruses, cause hantavirus pulmonary syndrome in the Americas. Currently no thera...
Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases

CITE Title : Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases Personal Author(s) : Lo, Michael K.;Albariño, César G.;Perry, Jason K.;Chang, Silvia;Tchesnokov, Egor P.;Guerrero, Lisa;Chakrabarti, Ayan;Shrivastava-Ranjan, Punya;Chatterjee, Payel;McMullan, Laura K.;Martin, Ross;Jordan, Robert;Götte, Matthias;Montgomery, Joel M.;Nichol, Stuart T.;Flint, Mike;Porter, Danielle;Spiropoulou, Christina F.; Published Date : October 07 2020 Source : Proc Natl Acad Sci U S A. 2020; 117(43):26946-26954 URL : https://stacks.cdc.gov/view/cdc/97659 Lo, Michael K. et al. (2020). Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases. 117(43). Lo, Michael K. et al. "Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases" 117, no. 43 (2020) Lo, Michael K. et al. "Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases" vol. 117, no. 43, 2020 Export RIS Citation Information.

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Lo, Michael K. ;

Albariño, César G.

October 07 2020 | Proc Natl Acad Sci U S A. 2020; 117(43):26946-26954

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Remdesivir is a broad-spectrum antiviral nucleotide prodrug that has been clinically evaluated in Ebola virus patients and recently received emergency...
Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing

CITE Title : Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing Personal Author(s) : Shrivastava-Ranjan, Punya;Flint, Mike;Bergeron, Éric;McElroy, Anita K.;Chatterjee, Payel;Albariño, César G.;Nichol, Stuart T.;Spiropoulou, Christina F.; Published Date : May 01 2018 Source : mBio. 9(3). URL : https://stacks.cdc.gov/view/cdc/53865 Shrivastava-Ranjan, Punya et al. (2018). Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing. 9(3). Shrivastava-Ranjan, Punya et al. "Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing" 9, no. 3 (2018) Shrivastava-Ranjan, Punya et al. "Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing" vol. 9, no. 3, 2018 Export RIS Citation Information.

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Shrivastava-Ranjan, Punya ;

Flint, Mike

May 01 2018 | mBio. 9(3).

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Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used choles...
646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans

CITE Title : 646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans Personal Author(s) : McElroy, Anita;Shrivastava-Ranjan, Punya;Harmon, Jessica;Martines, Roosecelis;Silva-Flannery, Luciana;Flietstra, Timothy;Kraft, Colleen;Mehta, Aneesh K;III, G Marshall Lyon;Varkey, Jay;Ribner, Bruce;Nichol, Stuart;Zaki, Sherif;Spiropoulou, Christina; Conference Author(s) : IDWeek (2018 October 3-7 : San Franciso, CA) Published Date : Nov 26 2018 Source : Open Forum Infect Dis. 2018; 5(Suppl 1):S234. URL : https://stacks.cdc.gov/view/cdc/60924 McElroy, Anita et al. (2018). 646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans. 5 McElroy, Anita et al. "646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans" 5 (2018) McElroy, Anita et al. "646. Activated Macrophages as Pathogenesis Factors in Ebola Virus Disease in Humans" vol. 5, 2018 Export RIS Citation Information.

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McElroy, Anita ;

Shrivastava-Ranjan, Punya

Nov 26 2018 | Open Forum Infect Dis. 2018; 5(Suppl 1):S234.

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BackgroundEbola virus disease (EVD) is associated with elevated cytokine levels that are more pronounced in fatal cases. This type of hyperinflammator...
Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1

CITE Title : Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1 Personal Author(s) : McElroy, Anita K.;Shrivastava-Ranjan, Punya;Harmon, Jessica R.;Martines, Roosecelis B.;Silva-Flannery, Luciana;Flietstra, Timothy D.;Kraft, Colleen S.;Mehta, Aneesh K.;Lyon, G. Marshall;Varkey, Jay B.;Ribner, Bruce S.;Nichol, Stuart T.;Zaki, Sherif R.;Spiropoulou, Christina F.; Published Date : Feb 2019 Source : Emerg Infect Dis. 25(2):290-298 URL : https://stacks.cdc.gov/view/cdc/75857 McElroy, Anita K. et al. (2019). Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1. 25(2). McElroy, Anita K. et al. "Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1" 25, no. 2 (2019) McElroy, Anita K. et al. "Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1" vol. 25, no. 2, 2019 Export RIS Citation Information.

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McElroy, Anita K. ;

Shrivastava-Ranjan, Punya

Feb 2019 | Emerg Infect Dis. 25(2):290-298

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Ebola virus disease (EVD) is associated with elevated cytokine levels, and hypercytokinemia is more pronounced in fatal cases. This type of hyperinfla...
25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation

CITE Title : 25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation Personal Author(s) : Shrivastava-Ranjan, Punya;Bergeron, Éric;Chakrabarti, Ayan K.;Albariño, César G.;Flint, Mike;Nichol, Stuart T.;Spiropoulou, Christina F.; Published Date : Dec 20 2016 Source : mBio. 2016; 7(6). URL : https://stacks.cdc.gov/view/cdc/43661 Shrivastava-Ranjan, Punya et al. (2016). 25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation. 7(6). Shrivastava-Ranjan, Punya et al. "25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation" 7, no. 6 (2016) Shrivastava-Ranjan, Punya et al. "25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation" vol. 7, no. 6, 2016 Export RIS Citation Information.

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Shrivastava-Ranjan, Punya ;

Bergeron, Éric

Dec 20 2016 | mBio. 2016; 7(6).

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Lassa virus (LASV) infection is a major public health concern due to high fatality rates and limited effective treatment. The interferon-stimulated ge...
Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease

CITE Title : Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease Personal Author(s) : Welch, Stephen R.;Ritter, Jana M.;Schuh, Amy J.;Genzer, Sarah C.;Sorvillo, Teresa E.;Harmon, Jessica R.;Coleman-McCray, JoAnn D.;Jain, Shilpi;Shrivastava-Ranjan, Punya;Seixas, Josilene Nascimento;Estetter, Lindsey B.;Fair, Pamela S.;Towner, Jonathan S.;Montgomery, Joel M.;Albariño, César G.;Spiropoulou, Christina F.;Spengler, Jessica R.; Published Date : 1 2023;1-2023; Source : Antiviral Res. 209:105490 URL : https://stacks.cdc.gov/view/cdc/154101 Welch, Stephen R. et al. (2023). Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease. 209 Welch, Stephen R. et al. "Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease" 209 (2023) Welch, Stephen R. et al. "Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease" vol. 209, 2023 Export RIS Citation Information.

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Welch, Stephen R. ;

Ritter, Jana M.

1 2023 | Antiviral Res. 209:105490

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Human infection with Sosuga virus (SOSV), a recently discovered pathogenic paramyxovirus, has been reported in one individual to date. No animal model...
Development of reverse genetic tools to study Chapare and Machupo viruses

CITE Title : Development of reverse genetic tools to study Chapare and Machupo viruses Personal Author(s) : Jain, Shilpi;Shrivastava-Ranjan, Punya;Flint, Mike;Montgomery, Joel M.;Spiropoulou, Christina F.;Albariño, Ćesar G.; Published Date : 11 2023;11-2023; Source : Virology. 588:109888 URL : https://stacks.cdc.gov/view/cdc/169818 Jain, Shilpi et al. (2023). Development of reverse genetic tools to study Chapare and Machupo viruses. 588 Jain, Shilpi et al. "Development of reverse genetic tools to study Chapare and Machupo viruses" 588 (2023) Jain, Shilpi et al. "Development of reverse genetic tools to study Chapare and Machupo viruses" vol. 588, 2023 Export RIS Citation Information.

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Jain, Shilpi ;

Shrivastava-Ranjan, Punya

11 2023 | Virology. 588:109888

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Arenaviruses are highly pathogenic viruses that pose a serious public health threat. Chapare virus (CHAV) and Machupo virus (MACV), two New World aren...