The Community Guide

- gsearch

Search Results

Narrow Results:

2015 6
2014 3
2013 1

Journal Article 10

1 - 10 of 10 Results

Refine Results

Refine Results:

Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease

CITE Title : Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease Personal Author(s) : Dahlman, James E.;Abudayyeh, Omar O.;Joung, Julia;Gootenberg, Jonathan S.;Zhang, Feng;Konermann, Silvana; Published Date : 11 2015;11-2015; Source : Nat Biotechnol. 33(11):1159-1161 URL : https://stacks.cdc.gov/view/cdc/37904 Dahlman, James E. et al. (2015). Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease. 33(11). Dahlman, James E. et al. "Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease" 33, no. 11 (2015) Dahlman, James E. et al. "Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease" vol. 33, no. 11, 2015 Export RIS Citation Information.

:

Dahlman, James E. ;

Abudayyeh, Omar O.

11 2015 | Nat Biotechnol. 33(11):1159-1161

:

We have developed a CRISPR-based method that uses catalytically active Cas9 and distinct single guide (sgRNA) constructs to knock out and activate dif...
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

CITE Title : Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells Personal Author(s) : Wu, Xuebing;Scott, David A.;Kriz, Andrea J.;Chiu, Anthony C.;Hsu, Patrick D.;Dadon, Daniel B.;Cheng, Albert W.;Trevino, Alexandro E.;Konermann, Silvana;Chen, Sidi;Jaenisch, Rudolf;Zhang, Feng;Sharp, Phillip A.; Published Date : 7 2014;7-2014; Source : Nat Biotechnol. 32(7):670-676 URL : https://stacks.cdc.gov/view/cdc/30092 Wu, Xuebing et al. (2014). Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. 32(7). Wu, Xuebing et al. "Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells" 32, no. 7 (2014) Wu, Xuebing et al. "Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells" vol. 32, no. 7, 2014 Export RIS Citation Information.

:

Wu, Xuebing ;

Scott, David A.

7 2014 | Nat Biotechnol. 32(7):670-676

:

Bacterial type II CRISPR-Cas9 systems have been widely adapted for RNA-guided genome editing and transcription regulation in eukaryotic cells, yet the...
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

CITE Title : CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling Personal Author(s) : Platt, Randall J.;Chen, Sidi;Zhou, Yang;Yim, Michael J.;Swiech, Lukasz;Kempton, Hannah R.;Dahlman, James E.;Parnas, Oren;Eisenhaure, Thomas M.;Jovanovic, Marko;Graham, Daniel B.;Jhunjhunwala, Siddharth;Xavier, Ramnik J.;Langer, Robert;Anderson, Daniel G.;Hacohen, Nir;Regev, Aviv;Feng, Guoping;Sharp, Phillip A.;Zhang, Feng; Published Date : 10 9 2014;10-9-; Source : Cell. 2014; 159(2):440-455 URL : https://stacks.cdc.gov/view/cdc/30201 Platt, Randall J. et al. (2014). CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling. 159(2). Platt, Randall J. et al. "CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling" 159, no. 2 (2014) Platt, Randall J. et al. "CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling" vol. 159, no. 2, 2014 Export RIS Citation Information.

:

Platt, Randall J. ;

Chen, Sidi

10 9 2014 | Cell. 2014; 159(2):440-455

:

CRISPR-Cas9 is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of Cas9 in vivo...
Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

CITE Title : Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis Personal Author(s) : Chen, Sidi;Sanjana, Neville E.;Zheng, Kaijie;Shalem, Ophir;Lee, Kyungheon;Shi, Xi;Scott, David A.;Song, Jun;Pan, Jen Q.;Weissleder, Ralph;Lee, Hakho;Zhang, Feng;Sharp, Phillip A.; Published Date : 3 12 2015;3-12-; Source : Cell. 2015; 160(6):1246-1260 URL : https://stacks.cdc.gov/view/cdc/30747 Chen, Sidi et al. (2015). Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. 160(6). Chen, Sidi et al. "Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis" 160, no. 6 (2015) Chen, Sidi et al. "Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis" vol. 160, no. 6, 2015 Export RIS Citation Information.

:

Chen, Sidi ;

Sanjana, Neville E.

3 12 2015 | Cell. 2015; 160(6):1246-1260

:

Genetic screens are powerful tools for identifying genes responsible for diverse phenotypes. Here we describe a genome-wide CRISPR/Cas9-mediated loss-...
High-throughput functional genomics using CRISPR-Cas9

CITE Title : High-throughput functional genomics using CRISPR-Cas9 Personal Author(s) : Shalem, Ophir;Sanjana, Neville E.;Zhang, Feng; Published Date : 5 2015;5-2015; Source : Nat Rev Genet. 2015; 16(5):299-311 URL : https://stacks.cdc.gov/view/cdc/32067 Shalem, Ophir et al. (2015). High-throughput functional genomics using CRISPR-Cas9. 16(5). Shalem, Ophir and Sanjana, Neville E. and Zhang, Feng "High-throughput functional genomics using CRISPR-Cas9" 16, no. 5 (2015) Shalem, Ophir et al. "High-throughput functional genomics using CRISPR-Cas9" vol. 16, no. 5, 2015 Export RIS Citation Information.

:

Shalem, Ophir ;

Sanjana, Neville E.

5 2015 | Nat Rev Genet. 2015; 16(5):299-311

:

Forward genetic screens are powerful tools for the discovery and functional annotation of genetic elements. Recently, the RNA-guided CRISPR (clustered...
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

CITE Title : In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9 Personal Author(s) : Swiech, Lukasz;Heidenreich, Matthias;Banerjee, Abhishek;Habib, Naomi;Li, Yinqing;Trombetta, John;Sur, Mriganka;Zhang, Feng; Published Date : 1 2015;1-2015; Source : Nat Biotechnol. 2014; 33(1):102-106 URL : https://stacks.cdc.gov/view/cdc/32021 Swiech, Lukasz et al. (2015). In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. 33(1). Swiech, Lukasz et al. "In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9" 33, no. 1 (2015) Swiech, Lukasz et al. "In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9" vol. 33, no. 1, 2015 Export RIS Citation Information.

:

Swiech, Lukasz ;

Heidenreich, Matthias

1 2015 | Nat Biotechnol. 2014; 33(1):102-106

:

Probing gene function in the mammalian brain can be greatly assisted with methods to manipulate the genome of neurons in vivo. The clustered, regularl...
Brains, Genes and Primates

CITE Title : Brains, Genes and Primates Personal Author(s) : Belmonte, Juan Carlos Izpisua;Callaway, Edward M.;Churchland, Patricia;Caddick, Sarah J.;Feng, Guoping;Homanics, Gregg E.;Lee, Kuo-Fen;Leopold, David A.;Miller, Cory T.;Mitchell, Jude F.;Mitalipov, Shoukhrat;Moutri, Alysson R.;Movshon, J. Anthony;Okano, Hideyuki;Reynolds, John H.;Ringach, Dario;Sejnowski, Terrence J.;Silva, Afonso C.;Strick, Peter L.;Wu, Jun;Zhang, Feng; Published Date : 5 6 2015 Source : Neuron. 2015; 86(3):617-631 URL : https://stacks.cdc.gov/view/cdc/31991 Belmonte, Juan Carlos Izpisua et al. (2015). Brains, Genes and Primates. 86(3). Belmonte, Juan Carlos Izpisua et al. "Brains, Genes and Primates" 86, no. 3 (2015) Belmonte, Juan Carlos Izpisua et al. "Brains, Genes and Primates" vol. 86, no. 3, 2015 Export RIS Citation Information.

:

Belmonte, Juan Carlos Izpisua ;

Callaway, Edward M.

5 6 2015 | Neuron. 2015; 86(3):617-631

:

One of the great strengths of the mouse model is the wide array of genetic tools that have been developed. Striking examples include methods for direc...
Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system

CITE Title : Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system Personal Author(s) : Zetsche, Bernd;Gootenberg, Jonathan S.;Abudayyeh, Omar O.;Slaymaker, Ian M.;Makarova, Kira S.;Essletzbichler, Patrick;Volz, Sara;Joung, Julia;van der Oost, John;Regev, Aviv;Koonin, Eugene V.;Zhang, Feng; Published Date : 10 22 2015;10-22-; Source : Cell. 163(3):759-771 URL : https://stacks.cdc.gov/view/cdc/37605 Zetsche, Bernd et al. (2015). Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system. 163(3). Zetsche, Bernd et al. "Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system" 163, no. 3 (2015) Zetsche, Bernd et al. "Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system" vol. 163, no. 3, 2015 Export RIS Citation Information.

:

Zetsche, Bernd ;

Gootenberg, Jonathan S.

10 22 2015 | Cell. 163(3):759-771

:

The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Cl...
Development and Applications of CRISPR-Cas9 for Genome Engineering

CITE Title : Development and Applications of CRISPR-Cas9 for Genome Engineering Personal Author(s) : Hsu, Patrick D.;Lander, Eric S.;Zhang, Feng; Published Date : 6 5 2014;6-5-; Source : Cell. 2014; 157(6):1262-1278 URL : https://stacks.cdc.gov/view/cdc/30309 Hsu, Patrick D. et al. (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering. 157(6). Hsu, Patrick D. and Lander, Eric S. and Zhang, Feng "Development and Applications of CRISPR-Cas9 for Genome Engineering" 157, no. 6 (2014) Hsu, Patrick D. et al. "Development and Applications of CRISPR-Cas9 for Genome Engineering" vol. 157, no. 6, 2014 Export RIS Citation Information.

:

Hsu, Patrick D. ;

Lander, Eric S.

6 5 2014 | Cell. 2014; 157(6):1262-1278

:

Recent advances in genome engineering technologies based on the CRISPR-associated RNA-guided endonuclease Cas9 are enabling the systematic interrogati...
CRISPR-assisted editing of bacterial genomes

CITE Title : CRISPR-assisted editing of bacterial genomes Personal Author(s) : Jiang, Wenyan;Bikard, David;Cox, David;Zhang, Feng;Marraffini, Luciano A.; Published Date : 3 2013 Source : Nat Biotechnol. 31(3):233-239 URL : https://stacks.cdc.gov/view/cdc/22571 Jiang, Wenyan et al. (2013). CRISPR-assisted editing of bacterial genomes. 31(3). Jiang, Wenyan et al. "CRISPR-assisted editing of bacterial genomes" 31, no. 3 (2013) Jiang, Wenyan et al. "CRISPR-assisted editing of bacterial genomes" vol. 31, no. 3, 2013 Export RIS Citation Information.

:

Jiang, Wenyan ;

Bikard, David

3 2013 | Nat Biotechnol. 31(3):233-239

:

Here we use the clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated Cas9 endonuclease complexed with dual-RNAs to introduc...