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- :Chen, Sidi ;Sanjana, Neville E.3 12 2015 | Cell. 2015; 160(6):1246-1260:Genetic screens are powerful tools for identifying genes responsible for diverse phenotypes. Here we describe a genome-wide CRISPR/Cas9-mediated loss-...
- :Swiech, Lukasz ;Heidenreich, Matthias1 2015 | Nat Biotechnol. 2014; 33(1):102-106:Probing gene function in the mammalian brain can be greatly assisted with methods to manipulate the genome of neurons in vivo. The clustered, regularl...
- :Belmonte, Juan Carlos Izpisua ;Callaway, Edward M.5 6 2015 | Neuron. 2015; 86(3):617-631:One of the great strengths of the mouse model is the wide array of genetic tools that have been developed. Striking examples include methods for direc...
- :Zetsche, Bernd ;Gootenberg, Jonathan S.10 22 2015 | Cell. 163(3):759-771:The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Cl...
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