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Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development

Personal Author:

Livio, Sofie; Strockbine, Nancy A.; Panchalingam, Sandra; Tennant, Sharon M.; Barry, Eileen M.; Marohn, Mark E.; Antonio, Martin; Hossain, Anowar; Mandomando, Inacio; Ochieng, John B.; Oundo, Joseph O.; Qureshi, Shahida; Ramamurthy, Thandavarayan; Tamboura, Boubou; Adegbola, Richard A.; Hossain, Mohammed Jahangir; Saha, Debasish; Sen, Sunil; Faruque, Abu Syed Golam; Alonso, Pedro L.; Breiman, Robert F.; Zaidi, Anita K. M.; Sur, Dipika; Sow, Samba O.; Berkeley, Lynette Y.; O'Reilly, Ciara E.; Mintz, Eric D.; Biswas, Kousick; Cohen, Dani; Farag, Tamer H.; Nasrin, Dilruba; Wu, Yukun; Blackwelder, William C.; Kotloff, Karen L.; Nataro, James P.; Levine, Myron M.;

Published Date:

Jun 23 2014

Source:

Clin Infect Dis. 2014; 59(7):933-941.

Description:

Shigella, a major diarrheal disease pathogen worldwide, is the target of vaccine development. The Global Enteric Multicenter Study (GEMS) investigated burden and etiology of moderate-to-severe diarrheal disease in children aged <60 months and matched...

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Staphylococcus aureus Bacteremia in Children of Rural Areas of The Gambia, 2008–2015

Personal Author:

Odutola, Aderonke; Bottomley, Christian; Zaman, Syed A.; Lindsay, Jodi; Shah, Muhammed; Hossain, Ilias; Ndiaye, Malick; Osuorah, Chidebere D.I.; Olatunji, Yekini; Badji, Henry; Ikumapayi, Usman N.A.; Manjang, Ahmad; Salaudeen, Rasheed; Ceesay, Lamin; Jasseh, Momodou; Adegbola, Richard A.; Corrah, Tumani; Hill, Philip C.; Greenwood, Brian M.; Mackenzie, Grant A.;

Published Date:

Apr 2019

Source:

Emerg Infect Dis. 25(4):701-709

Description:

Staphylococcus aureus bacteremia is a substantial cause of childhood disease and death, but few studies have described its epidemiology in developing countries. Using a population-based surveillance system for pneumonia, sepsis, and meningitis, we es...

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[PDF - 722.78 KB]
Exploring Household Economic Impacts of Childhood Diarrheal Illnesses in 3 African Settings

Personal Author:

Rheingans, Richard; Kukla, Matt; Adegbola, Richard A.; Saha, Debasish; Omore, Richard; Breiman, Robert F.; Sow, Samba O.; Onwuchekwa, Uma; Nasrin, Dilruba; Farag, Tamer H.; Kotloff, Karen L.; Levine, Myron M.;

Published Date:

Dec 2012

Source:

Clin Infect Dis. 2012; 55(Suppl 4):S317-S326.

Description:

Beyond the morbidity and mortality burden of childhood diarrhea in sub-Saharan African are significant economic costs to affected households. Using survey data from 3 of the 4 sites in sub-Saharan Africa (Gambia, Kenya, Mali) participating in the Glo...

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[PDF - 187.94 KB]
Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation

Personal Author:

Chaguza, Chrispin; Senghore, Madikay; Bojang, Ebrima; Gladstone, Rebecca A.; Lo, Stephanie W.; Tientcheu, Peggy-Estelle; Bancroft, Rowan E.; Worwui, Archibald; Foster-Nyarko, Ebenezer; Ceesay, Fatima; Okoi, Catherine; McGee, Lesley; Klugman, Keith P.; Breiman, Robert F.; Barer, Michael R.; Adegbola, Richard A.; Antonio, Martin; Bentley, Stephen D.; Kwambana-Adams, Brenda A.;

Published Date:

July 10 2020

Source:

Nat Commun. 11

Description:

Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little is known about genomic changes during natural colonisation. Here,...

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[PDF - 1.62 MB]