Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Yadouleton, Anges ; Sander, Anna-Lena ; Moreira-Soto, Andres ; Tchibozo, Carine ; Hounkanrin, Gildas ; Badou, Yvette ; Fischer, Carlo ; Krause, Nina ; Akogbeto, Petas ; de Oliveira Filho, Edmilson F. ; Dossou, Anges ; Brünink, Sebastian ; Aïssi, Melchior A. Joël ; Djingarey, Mamoudou Harouna ; Hounkpatin, Benjamin ; Nagel, Michael ; Drexler, Jan Felix
• Description:
  We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions.
• Subjects:
  Antibodies, Viral Coronavirus Infections COVID-19 Humans SARS-CoV-2 Sensitivity And Specificity Serologic Tests
• Source:
  Emerg Infect Dis. 27(1):233-237
• Pubmed ID:
  33261717
• Pubmed Central ID:
  PMC7774555
• Document Type:
  Journal Article
• Place as Subject:
  Benin
• Location:
  Africa
• Volume:
  27
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:63d898f1292535eab05891076b0b16adfc21e3c488b2375be9d29cf7c45b6a3f
• Download URL:
  https://stacks.cdc.gov/view/cdc/99992/cdc_99992_DS1.pdf
• File Type:
  [PDF - 1.38 MB ]