The disconnect between a national tuberculosis drug resistance survey and treatment outcomes: a lost opportunity

Click, E. S.; Chirenda, J.; Kibias, S.; Menzies, H. J.; Oeltmann, J. E.; Sentle, C.; Muribe, T.; Lere, T. D.; Makombe, R.; Bamrah, S.; Moore, B. K.; Cain, K. P.

doi:10.5588/ijtld.13.0710

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The disconnect between a national tuberculosis drug resistance survey and treatment outcomes: a lost opportunity

11 2014
By Click, E. S. ; Chirenda, J. ; Kibias, S. ; ...
http://dx.doi.org/10.5588/ijtld.13.0710
Source: Int J Tuberc Lung Dis. 18(11):1319-1322

[PDF-239.87 KB]

English

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Details:

Alternative Title:

Int J Tuberc Lung Dis
Personal Author:

Click, E. S. ; Chirenda, J. ; Kibias, S. ; Menzies, H. J. ; Oeltmann, J. E. ; ... More +

Click, E. S. ; Chirenda, J. ; Kibias, S. ; Menzies, H. J. ; Oeltmann, J. E. ; Sentle, C. ; Muribe, T. ; Lere, T. D. ; Makombe, R. ; Bamrah, S. ; Moore, B. K. ; Cain, K. P. Less -
Description:

We linked results from the Fourth Botswana National Drug Resistance Survey (DRS), 2007-2008, to patient records from the national Electronic Tuberculosis Registry to determine treatment outcomes. Of 915 new patients, 651 (71%) had treatment data available. Completion or cure was achieved for 10/15 (67%, 95%CI 42-85) with isoniazid monoresistance, (6/16, 38%, 95%CI 18-61) with multidrug resistance, while 73% (391/537, 95%CI 69-76) were susceptible to first-line drugs. The analysis was limited because of unavailable treatment records and undocumented outcomes. Prospective analyses following DRSs should be considered to ensure adequate outcome data.
Subjects:

[+]

Antitubercular Agents Botswana Female Follow-Up Studies Humans Isoniazid Male Mycobacterium Tuberculosis Registries Retrospective Studies Treatment Outcome Tuberculosis, Multidrug-Resistant
Keywords:

[+]

Drug Outcome Resistance Survey Treatment
Source:

Int J Tuberc Lung Dis. 18(11):1319-1322
Pubmed ID:

25299864
Pubmed Central ID:

PMC5931357
Document Type:

Journal Article
Funding:

CC999999/Intramural CDC HHSUnited States/
Volume:

18
Issue:

11
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:9d1799972c14fc9913b610d4411887774e7b6a2840a9a21c3d56ff8261e76600
Download URL:

https://stacks.cdc.gov/view/cdc/53783/cdc_53783_DS1.pdf
File Type:

	nihms744759.nxml	xml
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