Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Bouin, Alexis; Nguyen, Yohan; Wehbe, Michel; Renois, Fanny; Fornes, Paul; Bani-Sadr, Firouze; Metz, Damien; Andreoletti, Laurent

doi:10.3201/eid2208.160186

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Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Aug 2016
By Bouin, Alexis ; Nguyen, Yohan ; Wehbe, Michel ; ...
http://dx.doi.org/10.3201/eid2208.160186
Source: Emerg Infect Dis. 22(8):1488-1490.

[PDF-432.96 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Bouin, Alexis ; Nguyen, Yohan ; Wehbe, Michel ; Renois, Fanny ; Fornes, Paul ; ... More +

Bouin, Alexis ; Nguyen, Yohan ; Wehbe, Michel ; Renois, Fanny ; Fornes, Paul ; Bani-Sadr, Firouze ; Metz, Damien ; Andreoletti, Laurent Less -
Description:

We performed deep sequencing analysis of the enterovirus 5' noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10(2) copies/μg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.
Subjects:

[+]

5′ Terminally Deleted Populations Coxsackievirus B3 Dispatch Endomyocardial Enterovirus Heart Human Idiopathic Dilated Cardiomyopathy Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations In Human Endomyocardial Tissues Viruses
Source:

Emerg Infect Dis. 22(8):1488-1490.
Pubmed ID:

27434549
Pubmed Central ID:

PMC4982168
Document Type:

Journal Article
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:d876fe50d2e61d89c68a2bc3fc973009bf13360279ac231cfb9eda4bdc53cf4f
Download URL:

https://stacks.cdc.gov/view/cdc/40868/cdc_40868_DS1.pdf
File Type:

	16-0186-F.gif	gif
	16-0186-F.jpg	jpeg
	16-0186-Techapp-s1.pdf	pdf
	16-0186.nxml	bin

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