Perspectives on Cell Reprogramming with RNA

Sul, Jai-Yoon; Kim, Tae Kyung; Lee, Jae Hee; Eberwine, James

doi:10.1016/j.tibtech.2012.02.004

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Perspectives on Cell Reprogramming with RNA

Mar 27 2012
By Sul, Jai-Yoon ; Kim, Tae Kyung ; Lee, Jae Hee ; ...
http://dx.doi.org/10.1016/j.tibtech.2012.02.004
Source: Trends Biotechnol. 2012; 30(5):243-249.

[PDF-1.31 MB]

English

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Details:

Alternative Title:

Trends Biotechnol
Personal Author:

Sul, Jai-Yoon ; Kim, Tae Kyung ; Lee, Jae Hee ; Eberwine, James

Sul, Jai-Yoon ; Kim, Tae Kyung ; Lee, Jae Hee ; Eberwine, James Less -
Description:

Recent advances in cell reprogramming have permitted the development of different stem cell lines and specific differentiated cell types using distinct technologies. Cell reprogramming is largely mediated by DNA and RNA. In this review, we explore the RNA-mediated cell reprogramming to induce specific target cell generation including stem cells, brain cells and cardiac cells. The ability of RNA populations to produce direct cell to cell phenotypic conversion is called Transcriptome Induced PhenotypeRemodeling (TIPeR). The theory and utility of RNA use for cellular reprogramming is explored in this review.
Subjects:

[+]

Animals Cell Differentiation Cell Physiological Phenomena DNA Gene Expression Regulation Humans
Source:

Trends Biotechnol. 2012; 30(5):243-249.
Pubmed ID:

22459515
Pubmed Central ID:

PMC3335965
Document Type:

Journal Article
Funding:

DP004117/DP/NCCDPHP CDC HHS/United States ; DP1 OD004117/OD/NIH HHS/United States ; DP1 OD004117-05/OD/NIH HHS/United States

DP004117/DP/NCCDPHP CDC HHS/United States ; DP1 OD004117/OD/NIH HHS/United States ; DP1 OD004117-05/OD/NIH HHS/United States Less -
Volume:

30
Issue:

5
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:390c8792da1f18bbfd9cbecd97b53ddb1c49b4be711d3a460a30f3c35c2a39e5
Download URL:

https://stacks.cdc.gov/view/cdc/33350/cdc_33350_DS1.pdf
File Type:

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