Differentiation of Acute Q Fever from Other Infections in Patients Presenting to Hospitals, the Netherlands1

Keijmel, Stephan P.; Krijger, Elmer; Delsing, Corine E.; Sprong, Tom; Nabuurs-Franssen, Marrigje H.; Bleeker-Rovers, Chantal P.

doi:10.3201/eid2108.140196

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Differentiation of Acute Q Fever from Other Infections in Patients Presenting to Hospitals, the Netherlands1

Aug 2015
By Keijmel, Stephan P. ; Krijger, Elmer ; Delsing, Corine E. ; ...
http://dx.doi.org/10.3201/eid2108.140196
Source: Emerg Infect Dis. 21(8):1348-1356.

[PDF-520.30 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Keijmel, Stephan P. ; Krijger, Elmer ; Delsing, Corine E. ; Sprong, Tom ; Nabuurs-Franssen, Marrigje H. ; ... More +

Keijmel, Stephan P. ; Krijger, Elmer ; Delsing, Corine E. ; Sprong, Tom ; Nabuurs-Franssen, Marrigje H. ; Bleeker-Rovers, Chantal P. Less -
Description:

Differentiating acute Q fever from infections caused by other pathogens is essential. We conducted a retrospective case-control study to evaluate differences in clinical signs, symptoms, and outcomes for 82 patients with acute Q fever and 52 control patients who had pneumonia, fever and lower respiratory tract symptoms, or fever and hepatitis, but had negative serologic results for Q fever. Patients with acute Q fever were younger and had higher C-reactive protein levels but lower leukocyte counts. However, a large overlap was found. In patients with an indication for prophylaxis, chronic Q fever did not develop after patients received prophylaxis but did develop in 50% of patients who did not receive prophylaxis. Differentiating acute Q fever from other respiratory infections, fever, or hepatitis is not possible without serologic testing or PCR. If risk factors for chronic Q fever are present, prophylactic treatment is advised.
Subjects:

[+]

Acute Q Fever Bacteria Case–Control Study Chronic Q Fever Clinical Practice Coxiella Burnetii Differentiation Of Acute Q Fever From Other Infections In Patients Presenting To Hospitals, The Netherlands Hospital Prophylactic Treatment Prophylaxis Q Fever Research The Netherlands
Source:

Emerg Infect Dis. 21(8):1348-1356.
Pubmed ID:

26196955
Pubmed Central ID:

PMC4517711
Document Type:

Journal Article
Volume:

21
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:5f2b8ed4eccd7e2c50f87a9023fd419148a3e91e5ee405e1a1b462095ab6d897
Download URL:

https://stacks.cdc.gov/view/cdc/32639/cdc_32639_DS1.pdf
File Type:

	14-0196.nxml	txt
	license.txt	txt

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