Association Between Wrist Ratio and Carpal Tunnel Syndrome: Effect Modification by Body Mass Index

Details

• Personal Author:
  Deckow-Schaefer G ; Drury DL ; Foster J ; Garg, Arun ; Hegmann KT ; Kapellusch J ; Kendall R ; Koric A ; Merryweather A ; Ott U ; Thiese MS ; Tomich S ; Wertsch J ; Wood EM
• Description:
  Introduction: Previous studies have reported higher wrist ratios (WR) related to carpal tunnel syndrome (CTS) but have not assessed effect modification by obesity and may have inadequately controlled for confounders. Methods: Baseline data of a multicenter prospective cohort study were analyzed. CTS was defined by nerve conduction study (NCS) criteria and symptoms. Results: Among the 1,206 participants, a square-shaped wrist was associated with CTS after controlling for confounders (prevalence ratio = 2.27; 95% confidence interval [95% CI], 1.33-3.86). Body mass index (BMI) was a strong effect modifier on the relationship between WR and both CTS and abnormal NCS results, with normal weight strata of rectangular versus square wrists = 8.18 (95% CI, 1.63-49.96) and 7.12 (95% CI, 2.19-23.16), respectively. Discussion: A square wrist is significantly associated with CTS after controlling for confounders. Effect modification by high BMI masked the eightfold magnitude adjusted relationship seen between WR and CTS among normal weight participants. [Description provided by NIOSH]
• Subjects:
  Body Weight Demography Musculoskeletal Diseases Musculoskeletal System Occupational Health Safety Sex Characteristics
• Keywords:
  Analytical Processes Author Keywords: Carpal Tunnel Syndrome BMI Body Mass Index Body Measurements Body Weight Carpal Tunnel Syndrome CTS Demographic Characteristics Effect Modification Gender Factors Nerve Conduction Study Nerve Damage Neuropathy Obesity Sex Factors Statistical Analysis Upper Extremities Weight Factors Wrist

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• ISSN:
  0148-639X
• Document Type:
  Text
• Funding:
  Cooperative Agreement ; Grant
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 5 ; OSHA Region 8 ; Utah ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  56
• Issue:
  6
• NIOSHTIC Number:
  nn:20052062
• Citation:
  Muscle Nerve 2017 Dec; 56(6):1047-1053
• Contact Point Address:
  M. S. Thiese, Rocky Mountain Center for Occupational and Environmental Health, University of Utah, 391 Chipeta Way, Suite C, Salt Lake City, Utah 84108, USA
• Email:
  matt.thiese@hsc.utah.edu
• Federal Fiscal Year:
  2018
• Performing Organization:
  University of Wisconsin
• Peer Reviewed:
  True
• Start Date:
  20020930
• Source Full Name:
  Muscle & Nerve
• End Date:
  20100929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6c2527eef8e5b4e4980afff8f15154c4b91f25876ceb9cc325cde187ea9d03d9c07f6160cb57fa93dbc2074a3c62cd1b2508ea97c321c2a8d5d033de8c19c4b6
• Download URL:
  https://stacks.cdc.gov/view/cdc/211666/cdc_211666_DS1.pdf
• File Type:
  [PDF - 138.89 KB ]