Repeated Measures of FEV1 over Six to Twelve Months: What Change Is Abnormal?

Details

• Personal Author:
  Petsonk, Edward L. ; Wang, Mei Lin
• Description:
  Monitoring change in FEV1 ([DELTA]FEV1) is useful for assessing adverse respiratory effects in an individual, but high variability impedes reliable recognition of accelerated decline. The American Thoracic Society (ATS) recommends a >=15% year-to-year FEV1 decline for clinical significance. To evaluate the applicability of this criterion in health monitoring programs, we examined the mean, lower 5th percentile, and lower 5% cutoff value of [DELTA]FEV1 determined from 2 tests at 6- and 12-month intervals using data obtained with ATS-recommended equipment and procedures in 389 white male workers, each with 3 to 11 spirometry tests over 5 years. Results indicate that when healthy working males perform spirometry according to ATS standards, a yearly decline in FEV1 greater than 8% or 330 mL should not be considered normal, whereas the 15% ATS criterion could be appropriate in clinical settings. [Description provided by NIOSH]
• Subjects:
  Coal Coal Mining Lung Mining Occupational Health Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety Smokers
• Keywords:
  Airway-obstruction Airway-resistance Coal-miners Lung-function Mine-workers Pulmonary-system-disorders Respiratory-system-disorders Smoking Spirometry Surveillance Underground-miners

  More +
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  46
• Issue:
  6
• NIOSHTIC Number:
  nn:20025595
• Citation:
  J Occup Environ Med 2004 Jun; 46(6):591-595
• Contact Point Address:
  Edward L. Petsonk, MD, FCCP, NIOSH, Mail Stop H-G900.2, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  elp2@cdc.gov
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3cee4fa1103e967cbf0b8e4befc3de5af9a6741eac47b6a1a4be44f3d309721c0d6b87c2c17b88defe1b72c3a5104663f4f1e739ce5b4f1a1c5a4a5ebf024256
• Download URL:
  https://stacks.cdc.gov/view/cdc/196887/cdc_196887_DS1.pdf
• File Type:
  [PDF - 258.59 KB ]