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Understanding Viral Vector COVID-19 Vaccines

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    Updated Mar. 14, 2022

    What You Need to Know

    • Viral vector vaccines use a modified version of a virus that is different from the virus being targeted to deliver important instructions to our cells. The modified version of the virus is called a vector virus.

    • Like all vaccines, viral vector vaccines benefit people who get vaccinated by giving them protection against diseases like COVID-19 without them having to risk the serious consequences of getting sick.

    • CDC recommends that people who are starting their vaccine series or getting a booster dose get either Pfizer-BioNTech or Moderna (mRNA COVID-19 vaccines). The mRNA vaccines are preferred over Johnson & Johnson’s Janssen COVID-19 vaccine (viral vector) in most circumstances, but the J&J/Janssen COVID-19 vaccine may be considered in some situations.

    The Johnson & Johnson Janssen vaccine, a viral vector vaccine, is among the COVID-19 vaccines authorized for emergency use in the United States.

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